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PhD + Postdoc (Italy 🇮🇹) | 5+ yrs Exp.

🧠 #Neuroscience & #CancerBiology

🌍 Seeking #Postdoc in Europe/USA

🛂 Well-versed in EU Visa/Relocation

🇮🇳 Open to Sr. Scientist R&D (Biotech) in India

PIs & Recruiters: DM for CV & Publications 📥

#AcademicSky #PostdocJobs #Hiring #Europe #USA #Biotech

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🔬Tumor microbiota: A new frontier in #CancerBiology
A @cp-cancercell.bsky.social international consensus article, co-led by CeMM Scientific Director @mrescigno.bsky.social, outlines standards for a more reliable & reproducible detection of tumor-associated microbes.
➡️ bit.ly/3NQ2Jy7
📄 bit.ly/4sV0F79

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Work by Ramón Cervantes-Rivera, Luisa Nirvana González-Fernández, Atalia Ziret Romero Rosas, Sandra Jetsamari Figueroa Ortíz, Alejandra Ochoa-Zarzosa and Joel E. López-Meza at Universidad Michoacana de San Nicolás de Hidalgo.

#LifeSciences #Reproducibility #CancerBiology

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Aging and cancer hallmarks as therapeutic targets
www.scienceopen.com/hosted-docum...
#Aging #CancerHallmarks #TherapeuticTargets #CancerBiology #PrecisionMedicine

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Genetics and biological processes can strongly influence cancer development.
This week we explain:
• Hereditary #pancreaticcancer syndromes
• KRAS mutations
• Inflammation

These concepts help researchers understand why certain cancers develop and how they progress.
#CancerBiology #Genetics

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G/C-ending and synonymous codon bias define functional translational programs that shape human tissue and cancer proteomes Abstract. Codon usage bias is a fundamental feature of the genetic code, yet its impact on messenger RNA translation is incompletely defined. Here, we inte

Excited to share our new paper in NAR Genomics and Bioinformatics (Editor’s Choice).
We show that Synonymous codons are not as interchangeable as they seem and that codon bias helps define functional translational programs in humans.

#codonbias #translation #tRNA #cancerbiology

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Dreaming of a career in cancer research?
Join the International PhD Program at DKFZ - Germany’s largest biomedical research center.
Explore #cancerresearch including #cancerbiology, #bioinformatics, #epidemiology & #medicalphysics.
The Summer Selection is open now 👉 apply here: t1p.de/hl56b

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A schematic illustration shows substrate-bound mTORC2 at the plasma membrane and mTORC1 at the surface of the lysosome

A schematic illustration shows substrate-bound mTORC2 at the plasma membrane and mTORC1 at the surface of the lysosome

Explore the structural and mechanistic basis of the the PI3K/AKT/mTORpathway in this latest review from #biochemj #mTOR #AKT #PI3K #CancerBiology https://doi.org/10.1042/BCJ20253108

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Mag-Net Strong Anion Exchange Enables Isolation of Ovarian Cancer Ascites Extracellular Vesicles for Proteomic Biomarker Discovery

Work by Tyler T. Cooper at Université de Montréal.

#LifeSciences #Reproducibility #CancerBiology

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Bio-protocol's new issue is now live! 🎉
bio-protocol.org/en/archive?v...

Check out the latest step-by-step protocols in various #LifeSciences fields.

#BioinformaticsandComputationalBiology #CancerBiology #CellBiology #Microbiology #MolecularBiology #PlantScience

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8/
Thanks to all the authors!
Happy to discuss and collaborate.

#Entosis #CellDeath #CancerBiology #Cytoskeleton #ROCK1 #PLS3

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Image describes the two talks upcoming in the April Variant Effect Seminar. Olivia Zhang's talk: KBTBD4 Cancer Hotspot Mutations Drive Neomorphic Degradation of HDAC1/2 Corepressor Complexes. Yuta Yamamoto's talk: Scaled multidimensional assays of variant effect for hypertrophic cardiomyopathy. Sign up via the QR code or at varianteffect.org/seminar-series.

Image describes the two talks upcoming in the April Variant Effect Seminar. Olivia Zhang's talk: KBTBD4 Cancer Hotspot Mutations Drive Neomorphic Degradation of HDAC1/2 Corepressor Complexes. Yuta Yamamoto's talk: Scaled multidimensional assays of variant effect for hypertrophic cardiomyopathy. Sign up via the QR code or at varianteffect.org/seminar-series.

Save the date for April's Variant Effects Seminar, where we will be joined by two more speakers with talks covering cancer and cardiology topics.

#Genomics #CancerBiology #VariantInterpretation #DeepMutationalScanning #FunctionalGenomics #ResearchTalk #StructuralBiology #AtlasOfVariantEffect

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Follow @biohackingpathway for more

#CancerBiology #MetabolicCancer #InsulinResistance #TumorGrowth #CellBiology #Oncology #CancerResearch #ScientificDiscovery #wellnesscommunity #wellnesslife #wellnesshote l#wellbeingjourney #HealthScience #MedicalResearch

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Thank you @oncodaily.bsky.social for featuring this piece on GATA6 and treatment response in #PancreaticCancer. Not my day job, but I am glad to support #scicomm efforts that help deepen our understanding of one of the deadliest #cancers. #cancer #cancerbiology oncodaily.com/voices/melvi...

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Check out the latest step-by-step protocols in various #LifeSciences fields.

#Biochemistry #BioinformaticsandComputationalBiology #CancerBiology #CellBiology #Microbiology #MolecularBiology #Neuroscience #PlantScience #StemCell

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🧬 Oncogenic KRAS mutations (pancreatic, colorectal, lung cancers) stabilize these complexes, sustaining growth signalling.

Explore RAS at the complex level → new therapeutic insights.

#RAS #KRAS #RASopathies #CancerBiology #ComplexPortal

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🧬 New open access review from 'Genes to Cells'
📖 Processing of DNA Topoisomerase II–DNA–Protein Crosslinks Associated With Anticancer Drugs
👉 https://ow.ly/AhR550YlTbe

#DNARepair #CancerBiology #OpenAccess

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Illustration of TFAP4-mediated reactivation of TERT in non-HBV-associated hepatocellular carcinoma. Alcohol exposure increases CTCF expression, which promotes transcription of TFAP4. TFAP4 binds the TERT promoter (at approximately −111 nt), enhancing TERT gene transcription. Elevated TERT expression increases telomerase activity, stabilizes telomeres, and supports hepatocellular carcinoma progression and metastasis. The pathway is depicted within the nucleus of an HCC cell, leading to tumor growth in non-viral-associated liver cancer.

Illustration of TFAP4-mediated reactivation of TERT in non-HBV-associated hepatocellular carcinoma. Alcohol exposure increases CTCF expression, which promotes transcription of TFAP4. TFAP4 binds the TERT promoter (at approximately −111 nt), enhancing TERT gene transcription. Elevated TERT expression increases telomerase activity, stabilizes telomeres, and supports hepatocellular carcinoma progression and metastasis. The pathway is depicted within the nucleus of an HCC cell, leading to tumor growth in non-viral-associated liver cancer.

📎 Commentary Spotlight
Eversole & Chakraborty discuss how TFAP4 “unleashes” TERT activity in non-viral liver cancers and highlight therapeutic implications of targeting the TFAP4–TERT interaction.
🔗 doi.org/10.47248/chp...
#HCC #CancerBiology

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Illustration of TFAP4-mediated reactivation of TERT in non-HBV-associated hepatocellular carcinoma. Alcohol exposure increases CTCF expression, which promotes transcription of TFAP4. TFAP4 binds the TERT promoter (at approximately −111 nt), enhancing TERT gene transcription. Elevated TERT expression increases telomerase activity, stabilizes telomeres, and supports hepatocellular carcinoma progression and metastasis. The pathway is depicted within the nucleus of an HCC cell, leading to tumor growth in non-viral-associated liver cancer.

Illustration of TFAP4-mediated reactivation of TERT in non-HBV-associated hepatocellular carcinoma. Alcohol exposure increases CTCF expression, which promotes transcription of TFAP4. TFAP4 binds the TERT promoter (at approximately −111 nt), enhancing TERT gene transcription. Elevated TERT expression increases telomerase activity, stabilizes telomeres, and supports hepatocellular carcinoma progression and metastasis. The pathway is depicted within the nucleus of an HCC cell, leading to tumor growth in non-viral-associated liver cancer.

📎 Commentary Spotlight
Eversole & Chakraborty discuss how TFAP4 “unleashes” TERT activity in non-viral liver cancers and highlight therapeutic implications of targeting the TFAP4–TERT interaction.
🔗 doi.org/10.47248/chp...
#HCC #CancerBiology

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How does exercise influence #cancerbiology ?

At Loughborough University, Dr Mhairi Morris explains how her team uses the CellTiter-Glo® 3D Cell Viability #Assay to study breast cancer, obesity, and physical activity in 3D cell models.

Watch at: https://youtu.be/AYPimoDG_gU

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Weekly reads 16/2/26 From ecDNA to epigenomic priming: modeling what averages miss

Weekly reads 16/2/26:
From ecDNA to epigenomic priming: modeling what averages miss
open.substack.com/pub/behindth...

Overall theme: Averages hide, structure reveals.

#SingleCell #SpatialOmics #CancerBiology #ComputationalBiology #MultiOmics #AIinBiology

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Sensing Local Fibers in Pancreatic Tumors, Cancer Cells ‘Choose’ to Either Grow or Tolerate Treatment Pancreatic cancer cells’ surroundings determine whether they grow fast or become resistant to chemotherapy, a new study led by NYU Langone researchers shows.

New NYU-led research shows pancreatic cancer cells adapt dynamically to their environment, toggling between growth and treatment-survival states; a potential target for next-gen therapies. #CancerBiology #TCSC nyulangone.org/news/sensing...

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Check out the latest step-by-step protocols in various #LifeSciences fields.

#BioinformaticsandComputationalBiology #CancerBiology #CellBiology #DevelopmentalBiology #DrugDiscovery #Immunology #Mechanobiology #Microbiology #MolecularBiology

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Created by Dr. Spencer Watson uses hyperplexed immunofluorescence data. This work shows how microscopy and computer vision can be combined to better understand complex cellular systems.

#sciart #microscopy #computervision #cancerbiology #tumormicroenvironment #immunofluorescence #artinscience

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Weekly reads 9/2/25 Systemic programs and structured models across cancer and aging

Weekly reads 9/2/25:
Systemic programs and structured models across cancer and aging

open.substack.com/pub/behindth...

Mechanism + structure > scale alone.

#CancerBiology #SingleCell #Genomics #Aging #Immunology #AIinBiology #LineageTracing

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FEBS Press This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial-to-mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP-binding pa....

What if the extracellular matrix actively reprograms TGFβ signaling to drive metastasis?

Our new study reveals that the COMP–PMEPA1 axis promotes EMT and shifts signaling toward pSMAD1/5 in breast cancer cells.

🔗 doi.org/10.1002/1878...
#BreastCancer #EMT #CancerBiology #TumorMicroenvironment

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Weekly reads 2/2/26 How space, context, and uncertainty reshape cancer and single-cell biology

Weekly reads 2/2/26 :
How space, context, and uncertainty reshape cancer and single-cell biology

open.substack.com/pub/behindth...

Big theme: space + context + mechanism > black-box scale alone.

#SpatialOmics #SingleCell #CancerBiology #TumorMicroenvironment #AIinBiology #Immunology

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Check out the latest step-by-step protocols in various #LifeSciences fields.

#Biochemistry #BioinformaticsandComputationalBiology #CancerBiology #DevelopmentalBiology #Environmentalscience #Immunology #Mechanobiology #Microbiology #Neuroscience #PlantScience #StemCell

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🧬Mechanisms Linking Gut Microbiota Dysbiosis & RCC Progression Discover how microbial imbalance drives immune remodeling and tumor microenvironments in RCC.
📍 Global Microbiome Congress (GMC 2026)
🗓 June 15–16, 2026 | Boston, USA (Hybrid)
🔗 microbiomecongress.org
#Microbiome #RCC #CancerBiology

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Follow @biohackingpathway for more

#CancerBiology #MetabolicCancer #InsulinResistance #TumorGrowth #CellBiology #Oncology #CancerResearch #ScientificDiscovery #wellnesscommunity #wellnesslife #wellnesshote l#wellbeingjourney #HealthScience #MedicalResearch

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