SWISS LEAGUE | Per Hånberg might be HC La Chaux-de-Fonds next head coach #HCC swisshockeynews.ch/en/shn/men/swiss-hockey/...

SWISS LEAGUE | HC La Chaux-de-Fonds will face HC Sierre in the playoff final #HCC #EHCVisp swisshockeynews.ch/en/shn/men/swiss-hockey/...

This review highlights aberrant #neddylation as a driver of #HepatocellularCarcinoma, influencing infection, #tumor growth, invasion, and the #TumorMicroenvironment, while assessing inhibitors like MLN4924 & TAS4464 as promising #HCC therapies.

#OpenAccess: doi.org/10.1016/j.ge...

If you know...you KNOW. Truffle time is here.

Why do we shake our cocoa butter spray paint? Because perfectly tempered cocoa butter means beautiful shine, and movement is an essential part of that process. @chefrubberofficial
#TruffleTime #CocoButter #FredericksburgTX #Bean2Bar #HCC

Characteristic Genomic and Clinicopathologic Landscape of DNA Polymerase Epsilon Mutant Colorectal Adenocarcinomas – A Retrospective Cohort Study DNA polymerase epsilon catalytic subunit A (POLE) gene plays a crucial role in DNA repair and chromosomal replication. Mutations in the POLE gene have been linked to cancer, particularly colorectal carcinoma (CRC). However, the genomic landscape and pathological significance of POLE mutant CRC remain underreported. This study aimed to characterize the clinicopathologic features and genomic landscape of CRC harboring POLE mutations and to investigate the implications of co-occurring genetic alterations.

🧬 Can AI predict liver cancer survival? A new study shows that machine learning models can help forecast outcomes in liver cancer patients, offering potential to support clinical decision-making.
#AI #LiverCancer #MachineLearning #HCC
www.xiahepublishing.com/2310-8819/JC...

SWISS LEAGUE | Janik Loosli will stay with HC La Chaux-de-Fonds #HCC swisshockeynews.ch/en/shn/men/swiss-hockey/...

We welcomes submissions to the Ther Adv Med Onc Special Collection on Combined Immunotherapy Strategies for Advanced Hepatocellular Carcinoma. We invite work on ICI combinations, biomarkers, and translational insights.
buff.ly/e8XA6kU
#HCC #Immunotherapy #Oncology

SWISS LEAGUE | Emil Molin is set to extend his contract with HC La Chaux-de-Fonds #HCC swisshockeynews.ch/en/shn/men/swiss-hockey/...

Modeling liver cancer caused by chronic hepacivirus infection. Great collab with Rice Lab
@rockefeller.edu
heavy lift by Mariana Batista #HCV #HCC #livercancer #cancer #chronicinfection
doi.org/10.1016/j.jh...

🎯 HCC treatment is evolving…
TACE + immunotherapy + targeted therapy shows stronger outcomes—but are we ready to change practice?

⚠️ Promising data, but guidelines still need phase III confirmation

#GastroAGI #HCC #MedSky #Liver

Not a coding problem.
A system design problem.

Fix the system → accuracy follows.

#HealthTech #RiskAdjustment #HCC

Alanine catabolism as a targetable vulnerability for MYC-driven liver cancer Montoya et al. uncover a role for alanine as a conserved metabolic substrate for MYC-driven liver cancer. GPT2 is a therapeutic target for MYC-overexpressing liver tumors.

Really excited to present the latest publication from our lab.

Outstanding work by Ton Montoya who really conceptualized and led this project. He finds that MYC-driven liver cancer uses alanine as a fuel. Implications for new treatments for #HCC 🧪

@ctbatucsf.bsky.social @ucsfcancer.bsky.social

Very happy to be in Bristol to present our work on #bacterial #omics in #hepatocellular #carcinoma!

Oral presentation O3 at the HCC-UK 2026 Congress.

Roger Williams Inst. of Liver Studies
@kingscollegelondon.bsky.social

#hcc #liver #cancer #livercancer #gut #microbiome #microbiota #hccuk2026

🚨 Call for Papers!
Ther Adv Med Onc invites submissions to our Special Collection on combined immunotherapy for advanced HCC.
🗓 Deadline: 30 Oct 2026
🔗 Submit: buff.ly/e8XA6kU
#HCC #LiverCancer #Immunotherapy #Oncology

durch den Squashcourt und Heimspiel 13 2025/26.

Even in the middle of #huntingseason you need to warm-up.

#rostock #seawolves #stadthalle_inrostock #basketball #bundesliga #bbl #squash #hcc #spannung #entspannung #mvtutgut #lifeislive #liveislive #lifeisgood #livingthegoodlife #primetime

Functional Liver Imaging Score Derived from Gadoxetic Acid-enhanced MRI Predicts Cachexia and Prognosis in Hepatocellular Carcinoma Patients

This research evaluated the predictive role of FLIS in #HCC patients with #Cachexia, suggesting that FLIS may facilitate early identification and #Prognostic assessment, and offering new perspectives for improving patient care. #medsky

To read: doi.org/10.1007/s115...

Retrospective Analysis of Radiofrequency Ablation in Patients with Small Solitary Hepatocellular Carcinoma: Survival Outcomes and Development of a Machine Learning Prognostic Model

Using the #SEERDatabase, this study demonstrates promising #SurvivalOutcomes for patients with solitary #HCC lesions ≤5 cm treated with #RFA, validated by stratified analyses & #AIDriven models, promising a novel #therapeutic strategy. #medsky

Read: doi.org/10.1007/s115...

SWISS LEAGUE | HC La Chaux-de-Fonds signs Santiago Näf from EHC Chur #HCC #EHCChur swisshockeynews.ch/en/shn/men/swiss-hockey/...

This study shows that single-cell profiling of #HCC under anti-PD-1 therapy reveals #Tcell exhaustion trajectories linked to tumor–immune crosstalk, highlighting exhaustion as a key target to improve #immunotherapy outcomes. #SingleCellRNASequencing

#OpenAccess: doi.org/10.1016/j.ge...

MEDICAL REPORT | HCC's Noam Micheletti done for the season #HCC swisshockeynews.ch/en/medical-feed/nl-med/h...

DISCIPLINARY | Four-game suspension for HCC's Loïc In-Albon #HCC swisshockeynews.ch/en/shn/disciplinary/four...

HCC Subgroups May Guide Personalized Treatment, Patient Selection | Docwire News Machine learning-identified subgroups of patients with unresectable HCC treated with atezo-bev may help guide personalized treatment strategies and patient selection.

Researchers used machine learning to identify subgroups of patients with unresectable #HepatocellularCarcinoma treated with #atezolizumab and #bevacizumab with different patterns of progression and prognostic trajectories.
#HCC #hepatology #oncology

SheBelieves Cup Matchday 2 of 3 starts today, but we’re already working up an appetite for the FINAL. 😋

Don't forget to support local this weekend! 💜

#HCC #KenameSport #SheBelievesCup #Newark #Ironbound

#HCC: 3 enfoques terapéuticos que están cambiando el panorama clínico
🔹 PD-1
🔹 Anti-VEGF
🔹 TKI

📎 Más información: dengyuepharma.com
📧 info@dengyuemed.com
#CarcinomaHepatocelular #InmunoOncología #AntiVEGF #TKI #PD1 #TerapiaSistémica #DengYueMedicinasEnHongKong

#ICE and #LEO presence was reported at/on #HCC Houston City College - Eastside Campus at 6815 Rustic St. near Bldg D. early A.M. Eastside is also a polling location. Be vigilant.
Check www.harrisvotes.com/Vote-Centers for nearby options & wait times. Get out and #vote #Houston! #HarrisCo #TX #Texas

ASCO Publications

Adición de camrelizumab y rivoceranib a la quimioembolización transarterial mejora la supervivencia libre de progresión en pacientes con carcinoma hepatocelular irresecable #HCC #TACE ascopubs.org/doi/full/10....

DISCIPLINARY | Loïc In-Albon has been provisionally suspended #HCC swisshockeynews.ch/en/shn/disciplinary/loic...

Illustration of TFAP4-mediated reactivation of TERT in non-HBV-associated hepatocellular carcinoma. Alcohol exposure increases CTCF expression, which promotes transcription of TFAP4. TFAP4 binds the TERT promoter (at approximately −111 nt), enhancing TERT gene transcription. Elevated TERT expression increases telomerase activity, stabilizes telomeres, and supports hepatocellular carcinoma progression and metastasis. The pathway is depicted within the nucleus of an HCC cell, leading to tumor growth in non-viral-associated liver cancer.

📎 Commentary Spotlight
Eversole & Chakraborty discuss how TFAP4 “unleashes” TERT activity in non-viral liver cancers and highlight therapeutic implications of targeting the TFAP4–TERT interaction.
🔗 doi.org/10.47248/chp...
#HCC #CancerBiology

Schematic model of telomerase reactivation in non-HBV-associated hepatocellular carcinoma. CTCF binds to the TFAP4 promoter and increases TFAP4 expression. TFAP4 then binds directly to the TERT promoter, enhancing TERT mRNA transcription. Increased TERT expression leads to elevated telomerase activity and stabilization of telomeres. Ethanol exposure further upregulates TFAP4 and TERT in non-HBV HCC cells, while this regulatory pathway appears limited in HBV-associated HCC.

📘 CHP Archive Spotlight #08
Original Research (2024) | Lim et al.
TFAP4 directly reactivates TERT in non-HBV HCC — independent of promoter mutation.
CTCF → TFAP4 → TERT axis drives telomerase activation, especially in alcohol-related tumors.
🔗 doi.org/10.47248/chp...
#HCC #TERT #Telomerase

Illustration of TFAP4-mediated reactivation of TERT in non-HBV-associated hepatocellular carcinoma. Alcohol exposure increases CTCF expression, which promotes transcription of TFAP4. TFAP4 binds the TERT promoter (at approximately −111 nt), enhancing TERT gene transcription. Elevated TERT expression increases telomerase activity, stabilizes telomeres, and supports hepatocellular carcinoma progression and metastasis. The pathway is depicted within the nucleus of an HCC cell, leading to tumor growth in non-viral-associated liver cancer.

📎 Commentary Spotlight
Eversole & Chakraborty discuss how TFAP4 “unleashes” TERT activity in non-viral liver cancers and highlight therapeutic implications of targeting the TFAP4–TERT interaction.
🔗 doi.org/10.47248/chp...
#HCC #CancerBiology