This study shows that single-cell profiling of #HCC under anti-PD-1 therapy reveals #Tcell exhaustion trajectories linked to tumor–immune crosstalk, highlighting exhaustion as a key target to improve #immunotherapy outcomes. #SingleCellRNASequencing
#OpenAccess: doi.org/10.1016/j.ge...
#TrastuzumabEmtansine achieved a 47.2% response rate with manageable safety in #HER2positive #MetastaticBreastCancer after pyrotinib/trastuzumab+pertuzumab failure, identifying potential #biomarkers through #SingleCellRNASequencing.
#OpenAccess in #STTT: doi.org/10.1038/s413...
What Does Single-Cell RNA Sequencing Tell Us?
🎥 Watch Episode #27 with Dr. Verena Haage to explore how #SingleCellRNASequencing, #Microglia, and #Transcriptomics are transforming our understanding of #brain health, #aging, and #disease.
Watch the full episode on this link: youtu.be/ZRQzm6BKyqo?...
This study maps the immune landscape of #POAG using #SingleCellRNASequencing of 1.4 million #PBMCs, revealing immune remodeling with increased CD4+ & myeloid cells, and a disrupted balance between inflammatory & #NeuroprotectiveSignaling.
#OpenAccess #STTT: doi.org/10.1038/s413...
DeepSeq: High-Throughput Single-Cell RNA Sequencing Data Labeling via Web Search-Augmented Agentic Generative AI Foundation Models
Al Dajani, S. A., Sanchez, A. et al.
Paper
Details
#DeepSeq #SingleCellRNASequencing #AIFoundationModels
The integration of single-cell RNA sequencing and spatial transcriptomics reveals the tumor microenvironment and spatial organization of testicular diffuse large B-cell lymphomas
This new study combined #singlecellRNAsequencing (scRNA-seq) and spatial transcriptomics to reveal the #TumorMicroenvironment (TME) and spatial organization of primary testicular diffuse large B-cell lymphoma (PT-DLBCL). #medsky
#OpenAccess: www.sciencedirect.co...
Single-cell RNA sequencing reveals a distinct profile of bone immune microenvironment and decreased osteoclast differentiation in type 2 diabetic mice
This study systematically analyzes #bonemarrow (BM) cells in #Type2Diabetes (T2D) mice by #SingleCellRNASequencing (scRNA-seq) and explores the T2D-induced cellular and molecular changes in the BM microenvironment. #medsky
#OpenAccess: buff.ly/FD7OKbC
The integration of single-cell RNA sequencing and spatial transcriptomics reveals the tumor microenvironment and spatial organization of testicular diffuse large B-cell lymphomas
A new study combined #singlecellRNAsequencing (scRNA-seq) and spatial transcriptomics to reveal the #TumorMicroenvironment (TME) and spatial organization of primary testicular diffuse large B-cell lymphoma (PT-DLBCL).
#OpenAccess: www.sciencedirect.co...
