Thank you to @williamohmd.bsky.social for presenting #GrandRounds today on the future of #precisionmedicine. Watch his talk:
youtu.be/p0rLHE2pNhM?si…

The AudioGene Translational Dashboard for Diagnosing Autosomal Dominant Nonsyndromic Hearing Loss: Phenotypic Data Visualization and Analysis Study Background: Autosomal dominant nonsyndromic hearing loss (ADNSHL) is highly heterogeneous, with more than 64 genes implicated in its etiology. This complexity limits the diagnostic power of clinical examinations and audiometry alone, while existing computational approaches have achieved only moderate accuracy and often lack interpretability. As precision medicine increasingly emphasizes genotype-phenotype correlations, there is a recognized need for diagnostic tools that provide clinicians with transparent, interpretable outputs. Objective: This study aimed to develop and evaluate the AudioGene Translational Dashboard, an interpretable clinical informatics tool that integrates machine learning models and interactive visualizations to enhance genotype-phenotype correlations and support diagnostic decision-making in ADNSHL. Methods: We developed the AudioGene Translational Dashboard, integrating 2 machine learning models (AudioGene version 4 and AudioGene version 9.1) with 6 interactive visualization tools. AudioGene version 4 uses a multi-instance support vector machine classifier for patients with multiple audiograms, while AudioGene version 9.1 combines adaptive boosting, k-nearest neighbors, random forest models, and logistic regression for patients with a single audiogram. Visualizations include audiometric profile plots, audioprofile surfaces, clustering analyses, and data distribution charts designed to facilitate clinical interpretation. Results: The AudioGene Translational Dashboard was developed to address the “70/30” phenomenon, indicating a 74% likelihood that the causative gene is among the top 3 predicted genes, thereby providing clinicians with a clear confidence indicator (“green flag”) or a caution alert (“red flag”) during diagnosis. While this level of performance is well suited for hypothesis generation, the remaining uncertainty underscores the need for interpretive context in clinical decision-making. Visualization tools enhanced clinicians’ ability to interpret and correlate phenotypic data with predicted genetic outcomes, improving diagnostic confidence and interpretability. Conclusions: The AudioGene Translational Dashboard advances clinical informatics in genetic diagnosis of ADNSHL by integrating explainable artificial intelligence with interactive visualizations, enhancing clinical interpretability and diagnostic accuracy. This approach facilitates informed clinical decision-making, highlights the translational potential of genotype-phenotype computational models, and supports precision medicine in hearing loss diagnostics. Future enhancements will target improving class balance and incorporating additional user-customizable features to further optimize clinical applicability.

The AudioGene Translational Dashboard for Diagnosing Autosomal Dominant Nonsyndromic Hearing Loss: Phenotypic Data Visualization and Analysis Study #HearingLoss #GenotypePhenotype #PrecisionMedicine #DataVisualization #MachineLearning

#truenorthspatial #spatialbiology #genomics #lifesciences #biotech #precisionmedicine #innovation #research #canada #quebec #science #partnerships | PANORAMICS - A Vision INC. 🚀 True North Spatial 2026: a first edition made possible thanks to visionary partners like Illumina! 👌 As the summit concluded two weeks ago with remarkable success, we want to take a moment to recog...

🙏 PANORAMICS, founder of True North Spatial, would like to warmly thank illumina, a major partner, for their outstanding commitment.
+info: www.linkedin.com/feed/update/...
#TrueNorthSpatial #SpatialBiology #Genomics #LifeSciences #Biotech #PrecisionMedicine

Just scheduled!

The next @WCMEnglanderIPM #PrecisionMedicine #AI Working Group, "A Foundation Model Augmented Polygenic Risk Score for Neural Tube Defects," will be presented by #neuroscientist Dr. Alokkumar Jha next Friday at 11 am.

Register today!

A new drug doubles one-year survival in pancreatic cancer.
🙂 Another encouraging piece of news from Groupe UIG!
Read: medicalxpress.com/news/2026-04...
#Oncology #ClinicalTrials #PancreaticCancer #Biotech #Innovation #PrecisionMedicine #Healthcare

Decoding the "Logic Gates" of gRNA: Chemical Modifications as Control Switches
Latest in Molecules: A masterclass in how chemical engineering is solving the biggest bottlenecks of the #CRISPR system: off-target effects and lack of spatiotemporal control.
#PlantGenetics #PrecisionMedicine

What is a menin inhibitor? What are menin inhibitors? Leukemia expert Elias Jabbour, M.D., discusses which patients make the best candidates for this novel cancer therapy, how they work and possible side effects.

Menin inhibitors are an exciting new form of cancer therapy for certain leukemias, helping target disease at its genetic core. Precision medicine is not just coming, it is already changing cancer care. #Leukemia #TargetedTherapy #PrecisionMedicine #TCSC
www.mdanderson.org/cancerwise/w...

Remote care shouldn't feel like guesswork. 🙅‍♂️ Clinicians need data they can trust. RE.DOCTOR delivers hospital-grade vitals (ECG, SpO2, HR) directly to your platform via advanced smartphone optics. Get the precision of a clinic with the convenience of a pocket. Precision meets Portability: https://re.doctor #HealthTech #PrecisionMedicine #MedData #Telemedicine #REDOCTOR

Remote care shouldn't feel like guesswork. 🙅‍♂️

Clinicians need data they can trust. RE.DOCTOR delivers hospital-grade vitals (BG, SpO2, HR) directly to your platform via advanced smartphone optics.

Precision meets Portability: https://re.doctor

#HealthTech #PrecisionMedicine #Telemedicine

AI is powerful — but it’s not the whole story.
Dr. Dale Bredesen explores why evolutionary intelligence (EI) may be the real breakthrough driving improvements in cognition, biomarkers, and chronic disease outcomes.
Read more: https://www.apollohealthco.com/ai-or-ei/ #PrecisionMedicine

#Cancer #Treatment #Webcast #Virtual #April #Research #MinimalResidualDisease #DalhousieU #Leukemia #Lymphoma #CancerResearch #CancerCare #LLSCanada #PrecisionMedicine

#Cancer #Treatment #Webcast #Virtual #Genetics #April #Research #VCHhealthcare #Leukemia #Lymphoma #CancerResearch #CancerCare #LLSCanada #PrecisionMedicine

대장암 치료제 효과 예측, AI 기술로 생존율 높이는 3가지 이유 - IT Mania 도전인생 최근 영국 NHS에서 도입한 대장암 치료제 베바시주맙이 화제입니다. 하지만 모든 환자에게 효과가 있는 것은 아니며, 심각한 부작용 위험도 존재합니다. 이런 상황에서 암 환자의 치료 반응을 미리 예측하는 인공지능 기술이 등장해 주목받고 있습니다.

대장암 치료제 효과 예측, AI 기술로 생존율 높이는 3가지 이유

https://bit.ly/3Q7xpLV

#대장암 #인공지능 #정밀의료 #항암치료 #ColorectalCancer #AI #PrecisionMedicine

🧑‍🔬 Authors: Jialu Zhao, Xia Hu, Shujing Fu, Jialin Wang, Yan Zheng, Chen Chen, Jingchun Luo
📅 Year: 2026
📄 DOI: 10.1007/s43657-026-00314-4

#Metabolism #PublicHealth #MachineLearning #PrecisionMedicine #HealthTech #DataScience

Molecular Diagnostics -- How Gene Tests Can Help Guide Your Breast Cancer Treatment Plan You want the most effective treatment for your breast cancer. Learn how molecular diagnostics can guide your doctors toward a treatment that works best for your tumor.

These tests give your doctor a “molecular fingerprint” of your #breastcancer, helping them not only tailor your treatment but also understand how the cancer is behaving in your body. @webmd.com

#bcsm #precisionmedicine

Monaco's Royal & Sporting Excellence: Robots, Awards, Leclerc! #shorts: Princess Grace Hospital Center showcases the revolutionary da Vinci 5 surgical robot. Featuring force feedback and advanced visualization for enhanced precision and patient outcomes. #SurgicalRobot #PrecisionMedicine…

Without the right diagnostics, the best medicines make no difference – BioNews Central A new analysis argues that diagnostics, which match patients to appropriate treatments, are being overlooked globally, hindering progress against major diseases despite advances in targeted therapies and precision health. ...

A new analysis argues that #diagnostics, which match patients to appropriate #treatments, are being overlooked globally, hindering progress against major diseases despite advances in #TargetedTherapies and #PrecisionHealth.
#PrecisionMedicine #MedicalDiagnostics

The future of medicine = DNA + data. This study shows how combining genetic data with health records could transform precision care, if we fix the data gaps. sciencedirect.com/science/arti...
@CellCellPress

@dgsomucla
#glp1 #precisionmedicine

📚 Published by: Mengna Xu, Weixiao Liu, Fan Liu, Ping Xie et al.
📅 Published in: 2026
📄 DOI: 10.1007/s43657-025-00233-w

🔗 A promising new direction for #PrecisionMedicine and #CancerTreatment 🚀

Published by: Xiang Chen, Yuxi Chen, Tiantian Xiao, et al.
📅 Published on: November 11, 2021📄 Full Study: [DOI: 10.1007/s43657-021-00028-9] 🔗#PediatricResearch #GeneticMarkers #IbuprofenTherapy #Neonatology #PrecisionMedicine

By simply identifying biomarkers that are known to increase the severity of toxicities, pharmacogenomics testing allows clinicians to tailor treatment choices to improve tolerability and ultimately patient outcomes #oncologynursing #precisionmedicine
www.ons.org/publications...

Who’s most at risk for prostate cancer, and how is treatment evolving?

This episode breaks down risk factors, screening, and how care is becoming more personalized.

Listen here: buff.ly/WikqXR0

#ProstateCancer #ArteraAI #PrecisionMedicine

This #CVIA editorial emphasizes #CardiacMyosinInhibitors serve as a model for advancing #PrecisionMedicine underscoring importance of integrating mechanistic research with #clinical development to shape the next generation of #Cardiovascular treatments.

#OpenAccess cvia-journal.org/cardiac-myos...

UCLA researchers receive $13.9 million CIRM grant to identify drug targets for autism and schizophrenia using human stem cell models UCLA researchers have secured a $13.9 million grant from the California Institute for Regenerative Medicine to investigate the molecular and cellular mechanisms of autism and schizophrenia. Utilizing human stem cell models, the study aims to identify potential drug targets for these prevalent neurodevelopmental disorders.

The left image above shows stem cell-derived brain organoid (thanks @novitchlab.bsky.social). Right image: a cell-derived assembloid (thanks Drs. Samarasinghe & Miranda) #Neuroscience #PrecisionMedicine #Neurodevelopment www.uclahealth.org/news/release...

AI is reshaping oncology from diagnosis to personalized treatment.

Join AIIM-2026
📅 May 04–05, 2026 | 📍 Boston & Online
🔗 ai-medicalcongress.com

#AIIM2026 #AIinMedicine #OncologyAI #Radiology #PrecisionMedicine #HealthcareInnovation

AI in Radiomics Using Imaging Data to Predict Treatment Response
www.ekascloud.com/our-blog/ai-...
#ArtificialIntelligence #AI #MachineLearning #DeepLearning #DataScience #PredictiveAnalytics #AIHealthcare#Radiomics #MedicalImaging #Radiology #HealthcareAI #DigitalHealth #PrecisionMedicine

From biological principles to AI and back again | EMBL Key takeaways from a conference that brought together scientists from all over the world to discuss the role of AI in the life sciences

"Here are seven key takeaways from this transformative gathering." Apply it to data collection for anamneses. #estimates #affordability #precisionmedicine
#DebunkAI #statistics Thanks @embl.org
www.embl.org/news/science...

Stay ahead in healthcare innovation.
Subscribe to #LucidQuest's Weekly LQ AI Report for #AI breakthroughs, #PrecisionMedicine insights & #DigitalHealth trends.
Get tips & success stories delivered to your inbox. http://dlvr.it/TRxF27

Precision medicine and genetics are transforming epilepsy care.
At Quantum Neurodiagnostics, combining genetic insights with continuous EEG monitoring helps neurologists better understand seizures and deliver more personalized treatment.
#Epilepsy #Neurology #PrecisionMedicine

How can digital twins (DTs) help design cardiac therapies?

Personalized DTs can test epicardial “support jackets” on the right ventricle virtually, guiding doctors to pick the best material and thickness.

Link: doi.org/10.1016/j.jb...

#DigitalTwin #Cardio #PrecisionMedicine #EpicardialRestraint