Decoding the Bite: Sensory cues, host heterogeneity, and pathogen manipulation in mosquito host-seeking behavior

This review highlights heterogeneity in #MosquitoBiting preferences, gaps in host factor and #microbiota insights, and explores emerging solutions like omics, #MicrobiomeEngineering, and #CRISPR sensory disruption to advance #VectorBorneDisease control.
Read: doi.org/10.1016/j.dc...

Rothamsted Research (@rothamsted.bsky.social) Rothamsted gene-edited barley crop becomes first to receive a UK Precision Bred Organism marketing notice 🎉 By increasing lipid content in plant tissues, the barley provides a high-energy forage crop for ruminant livestock, improving feed efficiency👇 https://www.rothamsted.ac.uk/news/rothamsted-gene-edited-barley-crop-becomes-first-receive-uk-precision-bred-organism-marketing

🌱Researchers at Rothamsted Research used #CRISPR #GenomeEditing to develop high-energy barley for livestock feed that may help cut methane emissions. 👇
https://ow.ly/o3xj50Yzzv5

News from the lab: Genotyping genome-edited mutants made easier: Emeric Louis and colleagues introduce a parallel qPCR approach with an iGenotype index and R workflow for fast, robust, and scalable analysis. #GenomeEditing #CRISPR #Bioinformatics #Xenopus

New Epigenome Technologies Blog! bit.ly/4m4rZwY

"Engineering Epigenetic Editors Takes Gene Silencing Platforms A Step Closer to Therapeutic Evaluations"

Based on a preprint from jdfev.bsky.social at scribetx.bsky.social

#Epigenetics #Blogs #EpigeneticEditors #CRISPR #DNAm

We build on CROP-seq #CRISPR screening, whole-cell ATAC-seq and 10xGenomics Multiome protocols from @leifludwig.bsky.social @caleblareau.bsky.social, and mtDNA and gRNA enrichment approaches, to study how nuclear gene perturbations impact mtDNA heteroplasmy and copy number in mouse fibroblasts.

MitoPerturb-Seq identifies gene-specific single-cell responses to mitochondrial DNA depletion and heteroplasmy - Nature Structural & Molecular Biology Burr and Auckland et. al develop MitoPerturb-Seq, which combines single-cell screening with multiomics to link nuclear genes to mitochondrial DNA (mtDNA) dynamics. They unveil core regulators of mtDNA...

Really pleased to see this out @natsmb.nature.com: www.nature.com/articles/s41.... MitoPerturb-Seq combines #singlecell #CRISPR screening with whole-cell Multiome, to identify nuclear modifiers of mtDNA dynamics. @mitocamb.bsky.social @mrc-mbu.bsky.social @prudentlab.bsky.social and Stephen Burr

OR 'mosquito season' grows, scientists find what bugs them The threat of rare, but deadly disease is rising alongside mosquito populations in the Northwest. In response, scientists are researching how mosquitoes detect a common compound in natural…

#Mosquito season in the Pacific Northwest has grown by a month in some areas. The bugs are developing insecticide resistance. Dengue- and Zika-carrying species are already in CA — and could reach Seattle in 50 years.
UW researchers are using #CRISPR to find stronger repellents. The clock is ticking.

Why is the #BigBang shown as a #Tube? : Medium

Single-celled #Organism with no #Brain is capable of #Pavlovian #Learning : New Sci

#CRISPR makes enhanced #Cancer-fighting #Immune #Cells inside #Mice : Nature

Latest #KnowledgeLinks

knowledgezone.co.in/resources/bo...

🥔 In vivo hairy root system + #RUBY reporter → 100% #potato transformation WITHOUT sterile conditions

🔴 Red pigment = visual selection (no #GUS/GFP needed)
⚡ 2-week #CRISPR validation (StDL1): 96% #editing efficiency
🌱 Optimized: 2-week-old shoots, Atlantic variety

Synthego Celebrates Supreme Court’s Ruling Invalidating Agilent's CRISPR Patents Synthego has welcomed the U.S. Supreme Court's decision to invalidate Agilent's patents on CRISPR technology, marking a significant moment for gene editing innovation.

Synthego Celebrates Supreme Court’s Ruling Invalidating Agilent's CRISPR Patents #USA #Redwood_City #CRISPR #Synthego #Agilent

Sign above my new desk saying “welcome to the Urnov lab Lauren” with pictures of microscopes and science tools

First day of work!! Got my ID card and my email and scheduled meetings so I’ll call it a win. lucky to be here, honored as always to represent the #RareDisease community 🥲 #CRISPR

CasY7: An optimized Cas12i system for enhanced genome editing in monocot crops The Cas12i-derived nuclease CasY7 system achieved high editing efficiency in rice, maize, and wheat, notably enabling multiplex editing. This establishes CasY7 as a robust CRISPR tool for crop improv...

✂️This comprehensive validation of CasY7 across 942 #transgenic #plants confirmed robust editing in #maize, #rice, and #wheat, establishing CasY7 as a high-efficiency addition to the #CRISPR toolkit.

🧬 doi.org/10.1111/jipb...
@wileylifesci.bsky.social
#PlantSci #CropSci

Vet voer zorgt voor veel meer bijen Voer bijen een beetje bij met 6 specifieke sterolen, en de bijensterfte lijkt verleden tijd. Dat suggereert de uitkomst van een onderzoek naar de vraag…

Vet voer zorgt voor veel meer bijen
www.foodlog.nl/artikel/vet-...
#bijen #bijensterfte #pollen #sterolen #nutrienten #crispr

Traditional breeding methods have limits, and transgenic tools face regulatory barriers. Transgene‑free #GenomeEditing with #CRISPR offers a more precise path to improved crops 🌱
Check out the review 👉 https://ow.ly/9yEt50YzxqW

Aufgeklärt❗️🌱 Die Zulassungsbeschränkungen neuer Züchtungsmethoden treffen vor allem kleinere Akteure – und stärken damit genau die Marktmacht, die häufig kritisiert wird. #NGT #CRISPR #Innovation Mehr dazu hier: swiss-food.ch/artikel/waru...

How gene-targeting technology is transforming STI diagnosis Most people who have heard of clustered regularly interspaced short palindromic repeats (more commonly known as CRISPR) associate it with gene editing—the precise molecular scissors that allow…

How #gene-targeting #technology is transforming #STI #diagnosis ...

| #CRISPR | #microbiology | #bacteria | #microbes | By @unimelb.edu.au via @sciencex.bsky.social

🚀 Big buzz at #ASGCT25: #GeneEditing & #CRISPR headlines, 20% data-driven talk, 85% positive vibes on breakthrough therapies for #DMD & #rarediseases!🧬 Download our full #socialmedia report! http://dlvr.it/TRpD9k #GeneTherapy #SocialListening #LucidQuest
@ASGCTherapy @ESGCT

GRACE plasmids for mapping #CRISPR activity patterns can be found at www.addgene.org/browse/artic...
Thanks for sharing!

👁️👁️ In a new paper, IGI's Niren Murthy & collaborators use #CRISPR to attack melanoma in the eye. Read more: https://ow.ly/Is3l50Yzr6V

Entradas Música electrónica con BROMO en Teatros del Canal - Teatros del Canal Un viaje musical y visual cargado de significados y mensajes, de sonidos contundentes y texturas orgánicas, de paisajes imposibles de imágenes generativas

Esta noche acudiremos a los Teatros del Canal para ver un espectáculo musical y visual creado por Bromo-IDM y Paloma Peñarrubia concebido alrededor de las herramientas #CRISPR Promete ser muy interesante e innovador: ciencia y arte
www.teatroscanal.com/espectaculo/...
youtu.be/Zw9KPz_yyHU

Are you a #Masters student interested in translational
#cancer research, tumor immunology and #CRISPR screens? Then apply to our lab at the @impvienna.bsky.social in Vienna:

www.imp.ac.at/career/open-...

#oncology, #cancerresearch, #CRISPR

Figure showing the principle of the GRACE reporter: CRISPR mutagenesis inactivates an uORF that inhibits GFP translation. Below are several examples of Drosophila wing imaginal discs expressing GRACE and Cas12a+ under control of different Gal4 drivers.

Mapping #CRISPR activity patterns with GRACE. In vivo gene editing sometimes happens at unexpected places. Reporters, such as GRACE, light up the cells that have been mutated. Flies are at @vdrc-flies.bsky.social and plasmids @addgene.bsky.social

Described here:
www.nature.com/articles/s41...

CRISPR-Cas: The New "Molecular Lens" for H. pylori 🦠🧪

In ACS Sensors: A deep dive into the hierarchical design of CRISPR-Cas enabled biosensors for Helicobacter pylori.
#ScienceUpdate #CRISPR #MolecularBiology #Diagnostics #Hpyolori #BioEngineering

Efficiency vs. Specificity? #BroadInstitute's new Jacquere library says: "Why not both?" 🧬✨ Published in #CellGenomics, the Doench team introduces a data-driven balance using the aggregate CFD threshold of 4.8. It rescued 97 essential genes missed by previous libraries! 🌽📈
#CRISPR #GeneEditing

Tijdens het KAALSTAART festival,o.a. 4- 6 april in Amersfoort zijn speculatieve organen te zien, van Nicole Spit, van glas, keramiek en polymeerklei.

Wat voor (gepersonaliseerde) organen zouden we in een laboratorium kunnen creëren? Wat zijn de voor- en nadelen? #CRISPR #kaalstaart #artscience

DNA shape explains crucial gene-therapy challenges Researchers at Imperial College London, the MRC Laboratory of Medical Sciences (LMS), and the University of Sheffield have shown that the physical tw...

🧬 It’s not just #DNA code that matters – it’s the shape.

Scientists from @imperialinfect.bsky.social, @mrc-lms.bsky.social & @sheffielduni.bsky.social show that twisting DNA can trigger #CRISPR errors, opening the door to safer #GeneEditing.

Read more 👇 www.imperial.ac.uk/news/article... #Genomics

Digital interface displaying 'CRISPR in Clinical Trials 2026 Review' with futuristic medical graphics on a dark purple background.

The latest on #CRISPR in #ClinicalTrials, including testing treatments for high cholesterol, lupus, GI cancer, sepsis, hemophilia, and many many more. Read here: https://ow.ly/s4c150YzswO

Bei dem neuen Gesetzentwurf geht es um sog. Neue Genomische Techniken (NGTs). Das sind neuere Methoden, um vorhandene Gene in Organismen zu verändern. Die bekannteste ist die nobelpreisgekrönte Genschere #CRISPR. Damit kann man gezielt kleine genetische Veränderungen erzeugen.
5/

Too fast, too short: mini-hearts, genome editing, and the new biology of sudden cardiac death This editorial refers to ‘SLC4A3-related short QT syndrome assessed in human induced pluripotent stem cell-derived cardiomyocytes: mechanisms of ventricula

Thanks to the #EuropeanHeartJournal for inviting me to write an #editorial on the important topic and article on #SuddenCardiacDeath 🫀

academic.oup.com/eurheartj/ad...

@escardio.bsky.social #arrhythmia #fibrillation #organoid #crispr #stemcell #SQTS

🌾 CHROMOSOME ENGINEERING: #CRISPR targets satellite #DNA repeats to reshape entire #wheat chromosomes

✂️ Achieved:
• Chromosome truncation (9.8% rate)
• Whole #chromosome elimination (25% rate)
• Isochromosome formation
• New telomere addition
doi.org/10.1093/plph...