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Too fast, too short: mini-hearts, genome editing, and the new biology of sudden cardiac death This editorial refers to ‘SLC4A3-related short QT syndrome assessed in human induced pluripotent stem cell-derived cardiomyocytes: mechanisms of ventricula

Thanks to the #EuropeanHeartJournal for inviting me to write an #editorial on the important topic and article on #SuddenCardiacDeath 🫀

academic.oup.com/eurheartj/ad...

@escardio.bsky.social #arrhythmia #fibrillation #organoid #crispr #stemcell #SQTS

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Photo of Hans Clevers

Photo of Hans Clevers

Our new Special Issue has launched with a fascinating interview with @hansclevers.bsky.social where he discusses the future of #organoid and #StemCell research

"My personal opinion is that the strength of the organoids is their simplicity."

doi.org/10.1242/dmm....
@hubrechtinstitute.bsky.social

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Effects of human embryonic stem cell–derived Schwann cells for nerve regeneration after facial nerve injury
doi.org/10.1177/0963...
#stemcell #schwann #nerve #regeneration
@journals.sagepub.com

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Image cytometry differentiates CD34+ and CD133+ profiles of very small embryonic-like stem cells
doi.org/10.1177/0963...
#stemcell
@journals.sagepub.com

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Advancing the Battle against Cystic Fibrosis: Stem Cell and Gene Therapy Insights

Advancing the Battle against Cystic Fibrosis: Stem Cell and Gene Therapy Insights

This review examines #CysticFibrosis (CF) pathophysiology and the emerging role of #StemCell and #GeneTherapies, highlighting how these strategies could redefine CF management and improve #PatientOutcomes. #medsky

Full article here: doi.org/10.1007/s115...

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Dad’s social media plea to save his son’s life goes viral Juan Uribe said he left his job last year to focus his efforts on his son Max.

www.aol.com/dad-issues-u...

#stemcell #transplant

Save a life! Sign up to donate.

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StemRenu | #1 High-Performance Stem Cell Technology StemRenu is an advanced antioxidant containing signalling peptides, activating direct adult stem cells to promoting health, harnessing power of cell protection.

StemRenu a supercharged formula works at cellular level supporting health, restores body to balanced state. bit.ly/1YlOdbI #Stemcell

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How do cell lineages evolve, and how does that shape trait evolution?

Join our symposium Tracing Evolution Through Cell Lineages (Plön, 12–14 October). Hear perspectives from leading scientists and contribute with your own.
Read more at: bit.ly/3PCSkpQ

#EvoDevo #DevBio #StemCell #evolution

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新しい美容体験!凍結幹細胞培養上清液の施術メニューが登場 2026年4月1日より、3つのサロンで凍結幹細胞培養上清液を使用した施術メニューが開始。美しさを体感できる新しい美容体験をご紹介します。

新しい美容体験!凍結幹細胞培養上清液の施術メニューが登場 #東京都 #中央区 #アートネイチャー #幹細胞 #STEMCELL

2026年4月1日より、3つのサロンで凍結幹細胞培養上清液を使用した施術メニューが開始。美しさを体感できる新しい美容体験をご紹介します。

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Weekly reads: the thymus and aging, Aspen upbeat 1 year data, paired organoids - The Niche Stem cell biologist discusses recent research including on Aspen encouraging data at 1 year, thymus and aging, paired organoids.

Weekly reads: intriguing links between the thymus and aging, Aspen upbeat 1 year data on #stemcells for Parkinson's, paired organoids, more ipscell.com/2026/03/week... #stemcell

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Insights from derivation of human IPS #stemcell derived islet-like or off-target enterochromaffin (EC)-like cells in the pancreas #diabetes www.nature.com/articles/s41...

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StemRenu | #1 High-Performance Stem Cell Technology StemRenu is an advanced antioxidant containing signalling peptides, activating direct adult stem cells to promoting health, harnessing power of cell protection.

StemRenu provides growth factors, amino acids, biological sugars, minerals & antioxidants at cellular level. bit.ly/1YlOdbI #Stemcell

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What is in vivo reprogramming, its potential pros & cons? - The Niche Stem cell biologist discusses in vivo reprogramming, its pros and cons, and the potential applications in regenerative medicine.

What is in vivo reprogramming, its potential pros & cons? ipscell.com/2025/10/what... Why do people & biotechs want very much to only do partial in vivo reprogramming in humans? #stemcells #stemcell

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Illustration of a cell undergoing division, showing two nuclei forming within a translucent cell membrane.

Illustration of a cell undergoing division, showing two nuclei forming within a translucent cell membrane.

Opinion piece: The #FDA must regulate #StemCell therapies to mitigate risks to patients and the public. In PNAS Front Matter: https://ow.ly/4cVk50Ywta2

#StemCellTherapy #HHS #Evidence-basedMedicine #AdultStemCells #EmbryonicStemCells

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Hi from the new Community Manager - the Node An introduction to the Node's new Community Manager, Andrea Murillo

Hi from the new Community Manager

The Node welcomes Andrea Murillo as the new Community Manager. Here, @andreamurillo.bsky.social introduces herself to our #DevBio and #StemCell communities.

thenode.biologists.com/hi-from-the-...

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Schematics showing the mechanism of how ERK activity coordinates ME differentiation and cell cycle. When the pluripotent stem cells (PSCs) differentiate towards mesendoderm (ME), ERK activity increases. Multiple morphogens controlling ME differentiation contribute to the increase of ERK activity, which also quantitatively modulate ERK activity. Increased ERK activity promotes efficient TBXT expression without dramatic remodeling of cell cycle during ME differentiation. This is because the ranges of ERK activity that promote cell cycle progression and TBXT protein production are distinct. The distinct ERK activity response ranges are reflective of gene-specific variations in sensitivity to ERK regulation at both the transcriptional and translational levels. Created with the help of BioRender. Liang, H. (2025)

Schematics showing the mechanism of how ERK activity coordinates ME differentiation and cell cycle. When the pluripotent stem cells (PSCs) differentiate towards mesendoderm (ME), ERK activity increases. Multiple morphogens controlling ME differentiation contribute to the increase of ERK activity, which also quantitatively modulate ERK activity. Increased ERK activity promotes efficient TBXT expression without dramatic remodeling of cell cycle during ME differentiation. This is because the ranges of ERK activity that promote cell cycle progression and TBXT protein production are distinct. The distinct ERK activity response ranges are reflective of gene-specific variations in sensitivity to ERK regulation at both the transcriptional and translational levels. Created with the help of BioRender. Liang, H. (2025)

ERK regulates both proliferation & lineage specification during #embryo development, but how? This study shows that ERK levels modulate human pluripotent #StemCell differentiation into mesendoderm by fine-tuning its differentiation potential & cell division speed @plosbiology.org 🧪 plos.io/4seESa5

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Schematics showing the mechanism of how ERK activity coordinates ME differentiation and cell cycle. When the pluripotent stem cells (PSCs) differentiate towards mesendoderm (ME), ERK activity increases. Multiple morphogens controlling ME differentiation contribute to the increase of ERK activity, which also quantitatively modulate ERK activity. Increased ERK activity promotes efficient TBXT expression without dramatic remodeling of cell cycle during ME differentiation. This is because the ranges of ERK activity that promote cell cycle progression and TBXT protein production are distinct. The distinct ERK activity response ranges are reflective of gene-specific variations in sensitivity to ERK regulation at both the transcriptional and translational levels. Created with the help of BioRender. Liang, H. (2025)

Schematics showing the mechanism of how ERK activity coordinates ME differentiation and cell cycle. When the pluripotent stem cells (PSCs) differentiate towards mesendoderm (ME), ERK activity increases. Multiple morphogens controlling ME differentiation contribute to the increase of ERK activity, which also quantitatively modulate ERK activity. Increased ERK activity promotes efficient TBXT expression without dramatic remodeling of cell cycle during ME differentiation. This is because the ranges of ERK activity that promote cell cycle progression and TBXT protein production are distinct. The distinct ERK activity response ranges are reflective of gene-specific variations in sensitivity to ERK regulation at both the transcriptional and translational levels. Created with the help of BioRender. Liang, H. (2025)

ERK regulates both proliferation & lineage specification during #embryo development, but how? This study shows that ERK levels modulate human pluripotent #StemCell differentiation into mesendoderm by fine-tuning its differentiation potential & cell division speed @plosbiology.org 🧪 plos.io/4seESa5

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Schematics showing the mechanism of how ERK activity coordinates ME differentiation and cell cycle. When the pluripotent stem cells (PSCs) differentiate towards mesendoderm (ME), ERK activity increases. Multiple morphogens controlling ME differentiation contribute to the increase of ERK activity, which also quantitatively modulate ERK activity. Increased ERK activity promotes efficient TBXT expression without dramatic remodeling of cell cycle during ME differentiation. This is because the ranges of ERK activity that promote cell cycle progression and TBXT protein production are distinct. The distinct ERK activity response ranges are reflective of gene-specific variations in sensitivity to ERK regulation at both the transcriptional and translational levels. Created with the help of BioRender. Liang, H. (2025)

Schematics showing the mechanism of how ERK activity coordinates ME differentiation and cell cycle. When the pluripotent stem cells (PSCs) differentiate towards mesendoderm (ME), ERK activity increases. Multiple morphogens controlling ME differentiation contribute to the increase of ERK activity, which also quantitatively modulate ERK activity. Increased ERK activity promotes efficient TBXT expression without dramatic remodeling of cell cycle during ME differentiation. This is because the ranges of ERK activity that promote cell cycle progression and TBXT protein production are distinct. The distinct ERK activity response ranges are reflective of gene-specific variations in sensitivity to ERK regulation at both the transcriptional and translational levels. Created with the help of BioRender. Liang, H. (2025)

ERK regulates both proliferation & lineage specification during #embryo development, but how? This study shows that ERK levels modulate human pluripotent #StemCell differentiation into mesendoderm by fine-tuning its differentiation potential & cell division speed @plosbiology.org 🧪 plos.io/4seESa5

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#NIH #RESEARCH #STEMCELL
'IS IT POSSIBLE TO REPAIR AND REGENERATE NIH TO ITS ORIGINAL FORM AND FUNCTION?
DON'T GET ME WRONG THERE WERE ISSUES WITH THE NIH BUT IT IS PART OF A SHITHOLE COUNTRY!'
BARBARA NOVAK

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Two researchers in white lab coats and blue medical gloves looking at a slide in a stem cell lab

Two researchers in white lab coats and blue medical gloves looking at a slide in a stem cell lab

Dean's POV 📸 Introducing the Center for #StemCell Engineering in the Doheny Building, a collaboration between @USCStemCell and @USCViterbi Biomedical Engineering. It will engineer cells and tissues and advance tools in physiology, omics, computation, AI, and machine learning. https://bit.ly/4qnDd1e

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Serum coating enables feeder-free culture of naive human pluripotent stem cells preserving developmental potential - The EMBO Journal Naive human pluripotent stem cells (hPSCs) represent a pre-implantation epiblast state able to efficiently differentiate into embryonic and extraembryonic pre-implantation lineages and to self-organis...

Eliminating the confounding effects of human pluripotent #stemcell co-culture with MEFs:
@grazianomartello.bsky.social @leeboratory.bsky.social @jzylicz.bsky.social and collaborators describe a serum coating approach for feeder-free culture of naïve hPSCs
link.springer.com/article/10.1...

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llustration of a cell undergoing division, showing two nuclei forming within a translucent cell membrane

llustration of a cell undergoing division, showing two nuclei forming within a translucent cell membrane

Opinion piece: The #FDA must regulate #StemCell therapies to mitigate risks to patients and the public. In PNAS Front Matter: https://ow.ly/RRoL50Yttgt

#StemCellTherapy #HHS #Evidence-basedMedicine #AdultStemCells #EmbryonicStemCells

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Thanks for sharing the incredible work of @crumplab.bsky.social #StemCell

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RESEARCH PAPER: Transcriptional derepression of negative regulators of MAP kinase supports maintenance of diapause ES cells in the pluripotent state
By Zhang et al., and Alexander Tarakhovsky
➡️ https://genesdev.cshlp.org/content/40/5-6/319.full

The Rockefeller University
#embryo #stemcell

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At #GfE2026, Thomas Bosch from Kiel University (CAU) challenges the host gene-centric view of biology, demonstrating in beautiful work how microbes change #development, #StemCell differentiation, and even #behaviour. Check out doi.org/10.1073/pnas... doi.org/10.1016/j.cu... doi.org/10.1101/2024...

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Early encouraging UC Davis trial data on cell therapy for spina bifida - The Niche Stem cell biologist discusses a new Lancet paper describing early results on a cell therapy for spina bifida.

ICYMI from Friday --> Upbeat news as early UC Davis trial data on cell therapy for spina bifida looks very encouraging so far ipscell.com/2026/03/earl... #stemcells #stemcell

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Funding Results - Stem Cell Network Learn more about SCN’s funded projects On June 16 2025, SCN was pleased to allocate $13.5M to support 36 research projects and clinical trials across the country, with 63 partner organizations committ...

(1/5) This #IWD2026, SCN celebrates the women whose leadership is advancing world-class #StemCell and #RegenMed research across Canada. 🇨🇦

From developmental research to commercialization, women are driving innovation, mentoring future leaders, and accelerating progress for patients and families. ✨

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🧬 HISTORIC: Japan approved the world's first iPS cell therapies as products.
"ReHeart" — cell sheet repairing damaged hearts
"Amshepri" — dopamine neurons for Parkinson's
20 years from Yamanaka's Nobel discovery to real medicine.
#iPSCells #StemCell #RegenerativeMedicine

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An Updated Guide To #HairFollicle #StemCell Markers And Changes In Their Expression With #Aging https://ow.ly/ztsG50YkYcC #Dermatology #HairResearch #CutaneousBiology #dermsky

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Check out the latest step-by-step protocols in various #LifeSciences fields.

#Biochemistry #BioinformaticsandComputationalBiology #CancerBiology #CellBiology #Microbiology #MolecularBiology #Neuroscience #PlantScience #StemCell

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