Bei dem neuen Gesetzentwurf geht es um sog. Neue Genomische Techniken (NGTs). Das sind neuere Methoden, um vorhandene Gene in Organismen zu verändern. Die bekannteste ist die nobelpreisgekrönte Genschere #CRISPR. Damit kann man gezielt kleine genetische Veränderungen erzeugen.
5/

Too fast, too short: mini-hearts, genome editing, and the new biology of sudden cardiac death This editorial refers to ‘SLC4A3-related short QT syndrome assessed in human induced pluripotent stem cell-derived cardiomyocytes: mechanisms of ventricula

Thanks to the #EuropeanHeartJournal for inviting me to write an #editorial on the important topic and article on #SuddenCardiacDeath 🫀

academic.oup.com/eurheartj/ad...

@escardio.bsky.social #arrhythmia #fibrillation #organoid #crispr #stemcell #SQTS

🌾 CHROMOSOME ENGINEERING: #CRISPR targets satellite #DNA repeats to reshape entire #wheat chromosomes

✂️ Achieved:
• Chromosome truncation (9.8% rate)
• Whole #chromosome elimination (25% rate)
• Isochromosome formation
• New telomere addition
doi.org/10.1093/plph...

En el número de este mes de @muyinteresante.com se incluye un artículo que escribí sobre la posibilidad de editar genéticamente (por ejemplo con #CRISPR) embriones humanos. Algo ilegal, imprudente, científicamente arriesgado y éticamente controvertido en la España de hoy en día.

I am so happy to see @stedhammer.bsky.social last thesis chapter taking the shape of a publication. We looked into the role of the elusive GGAs cargo sorting adaptors. Alex‘s works hints at a role in the modulation of the binding of AP-1 adaptors to its clients #membranes #trafficking #CRISPR

Gene Editing Therapy in Cardiovascular Disease: 2026 ACC Scientific Statement: A Report of the American College of Cardiology Download article citation: If you have the appropriate software installed, you can download article citation data to the citation manager of your choice. Simply select your manager software from the list below and click Download.

New 2026 ACC scientific statement reviews gene editing therapy in #CVD, covering the science, early targets (monogenic diseases), and key ethical and cost challenges. Clinicians play a critical role in guiding safe, equitable use. https://bit.ly/4rYSW6W

#JACC #CRISPR #cvGenetics #CardioSky

CTGCT Science Talks April - Dr. Thomas Fox - CTGCT On Monday, 13th of April 2026, 2:00 PM (Ljubljana/Berlin time),Dr. Thomas Fox, from the Dana-Farber Cancer Institute & Boston Children’s Hospital, Harvard Medical School and UCL Institute of Immunity ...

⏰ Don't miss the next #CTGCT #ScienceTalks with Dr. Thomas Fox! Explore the future of Programmable T Cell Therapies:

📅 Monday, April 13, 2026 🕒 2:00 PM
ctgct.si/en/objave/ct...

#Biotech #TCell #CRISPR

🥝 SURPRISING FIND: #Kiwifruit LEAFY genes sculpt flowers but DON'T control flowering time

🔬 Two AcLFY genes regulate:
✓ Flower organ development (petals, stamens)
✓ Plant architecture
✗ Flowering time (unlike other plants!)

#CRISPR double #knockout → severe flower defects, poor #pollination

Rusland ontwikkelt tarwe die tot dubbel zoveel graan produceert Key takeaways Onderzoekers van het Skolkovo Institute of Science and Technology hebben een belangrijke stap gezet in de tarweproductie. Ze bewerkten het tarwegenoom succesvol met de CRISPR-Cas9-techniek. Daarmee passen Russische wetenschappers deze methode voor het eerst toe op tarwe, blijkt uit nieuw onderzoek van Skoltech. Onverwacht neveneffect Aanvankelijk richtte het team zich op een gen […]

Rusland ontwikkelt tarwe die tot dubbel zoveel graan produceert #Rusland #tarwe #graan #CRISPR #genetischeModificatie

Whatever the future
holds in store,
we’ll make sure
you are part of it
#cloning #dna #rna #geneticengineering #stem #humans #genome #artificalintelligence #crispr #elon #elonmusk #biotech

Endless Cloning Myth Challenged as Mouse Line Fails at Generation 58
discoverwildscience.com
#cloning #dna #rna #geneticengineering #stem #humans #genome #artificalintelligence #crispr #elon #elonmusk #biotech

Supercoiling not only brings DNA to life (and makes it dance) but also changes how key proteins such as #CRISPR interact with it. Thanks @qmsmith.bsky.social for the brilliant collaboration, Sylvia for developing an amazing new #imageanalysis pipeline & @eddierollins.bsky.social for beautiful #AFM.

Structural basis of supercoiling-induced CRISPR–Cas9 off-target activity - Nature Cas9 structures explain topology sensing and off-target activation.

1/11 In our story out today in @nature.com , we showcase the molecular mechanisms that enable Cas9 to bind and cleave negatively supercoiled ((-)SC) off-targets! 🧬🧵

🔗 www.nature.com/articles/s41...

#CRISPR #Cas9 #DNATopology #AFM #CryoEM #SingleMolecule #Biophysics

🧪 96-well plate analysis with CleanFinder

From FASTQ to full editing overview in seconds:
• Plate-wide genotyping heatmap
• Efficiency & frameshift
• KO detection in diploid cells
• Repairome signatures (NHEJ, MMEJ, HDR)

In your browser.
🔗 cleanfinder.org

#CRISPR #GenomeEditing #Bioinformatics

#Genètica #CRISPR
A l' @agenciasinc.es  llegim 
Logran reprogramar células inmunitarias contra el cáncer dentro del organismo
🔗 www.agenciasinc.es/Noticias/Logran-reprogra...

🧬 CleanFinder Genome Viewer

Visualize gene structure, gRNA cut sites, CDS and protein sequences, all in one place.
Includes prediction of mRNA decay to better interpret editing outcomes.

From sequence → function.
🔗 cleanfinder.org/genome_viewer

#CRISPR #GenomeEditing #Bioinformatics

Samelson et al. (2026) just dropped a *Cell* paper on tau proteostasis! They used CRISPR screens in iPSC-derived neurons to find that CRL5-SOCS4 ubiquitinates tau. This looks like a key mechanism in Alzheimer's resilience. #Alzheimers #Neuroscience #CRISPR
Check out the video.
youtu.be/jJr7fQ49HaI

📚#EpigeneticEditing
Rewires gene expression without altering #DNA—via reversible DNA & histone modifications. Promising for #GeneRegulation in genetic disorders & cancer Challenges: delivery, epigenetic memory, biomarkers. A shift from gene repair → reprogramming beyond #CRISPR
🔗 ow.ly/9JcL50Yw9AT

The need for causal data is clear: ​​the brain is one of the most complex systems​, unlocking this biology requires massively multiplexed gene perturbation directly within its native context.

This is the future of scalable drug discovery.
#SystemsBiology #CRISPR #AI #BiotechInnovation

4 years ago, we launched our #CellEDITService. #FluidFM mechanically delivers #CRISPR RNPs directly to the nucleus without vectors. No more probability or endless screening. KI, multiplex, iPSCs... You name it, we edit it. www.cytosurge.com/solutions/services/fluid...

Digital medical interface displaying detailed anatomical diagrams of the heart, lungs, kidneys, and digestive system on a dark purple background.

Hot off the presses — our 2026 review of #CRISPR in #ClinicalTrials. Read here for the latest on CRISPR for #cancer, #HeartDisease, #AutoimmuneDisorders, #infections, #RareDisease, and more: https://ow.ly/XkI550YxSPv

CleanFinder

🚀 Introducing CleanFinder

A browser-native framework for comprehensive genome editing analysis.

Deterministic, scalable, and designed to resolve complex editing outcomes across Illumina and ONT datasets, including PE and BE.

Try it: cleanfinder.org

#CRISPR #GenomeEditing #Bioinformatics

We have been granted a key #patent for our CRISPR-BMC genome-editing technology. This patent opens significant potential for the further commercial application of the patented nucleases. Press release: t1p.de/pbgn7 #enzyme #protein #smallmolecules #CRISPR

🇨🇳 BREAKTHROUGH: #WIMI Biotech & Shanghai Jiao Tong University unveil #CasY7 - China's first fully independent #CRISPR gene editing system

✂️ 87.7% efficiency in #maize (2.7× better than #Cpf1)
🌾 Validated across 12 major crops
🧬 100% proprietary IP - no foreign dependencies

🌾 NEW SERVICE: #FoxtailMillet #GeneEditing from WIMI Biotech

✂️ #CRISPR #knockout validated
🧬 Agrobacterium-mediated transformation
⏱️ 6-8 months to T₀ plants
✅ Molecular verification + seeds included

Elite inbred lines | Single-copy insertion | Fast & stable

sales@wimibiotech.com

I'll take "pickled punks" for $500, Alex.

Source: Alien Resurrection (1997).

#SanFrancisco #LosAngeles #California #SiliconValley #Biotechnology #Crispr #NetworkState #FreedomCities #PeterThiel #JDVance #ElonMusk #CurtisYarvin #AlexKarp #SamAltman

🚀 Big buzz at #ASGCT25: #GeneEditing & #CRISPR headlines, 20% data-driven talk, 85% positive vibes on breakthrough therapies for #DMD & #rarediseases!🧬 Download our full #socialmedia report! http://dlvr.it/TRdbxW #GeneTherapy #SocialListening #LucidQuest
@ASGCTherapy @ESGCT

Original post on webpronews.com

A Grass That Could Transform Your Steak: Inside the UK’s Bold Bet on Gene-Edited Ryegrass for Cattle The UK has approved the first outdoor trial of gene-edited ryegrass designed to boost fat cont...

#HealthRevolution #CRISPR #cattle #feed #gene-edited […]

[Original post on webpronews.com]

Diagnostic assay shows potential for culture-negative fungal keratitis Researchers have developed a CRISPR assay that has shown good accuracy for diagnosing fungal keratitis in patients with negative smear and culture results.

#MedNews - Researchers have developed a #CRISPR assay that has shown good accuracy for diagnosing fungal #keratitis in patients with negative smear and culture results.

Full story 👉 buff.ly/MDYy2ch

#EyeSky

Synergistic engineering of Casδ nuclease for robust genome editing A hierarchical engineering strategy was used to enhance the editing activity of Casδ, yielding an optimized variant termed enCasδ. This variant enables robust genome editing in animal cells and plant...

Meet a hierarchical engineering strategy that improves Casδ-1 #genome editing activity by enhancing its interactions with crRNA, PAM duplex, single-stranded #DNA substrate, and #RNA–DNA heteroduplex.
Read it for free!
doi.org/10.1111/jipb...
@wileylifesci.bsky.social
#PlantSci #CRISPR #OpenAccess