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Wishing a #HappyEaster to everyone celebrating!

Take the chance to unwind, recharge, and enjoy a bit of spring sunshine. 🌞💐

From all of us at #Genome,
Have a wonderful Easter Sunday! ✨

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Wishing everyone a peaceful, restorative #EasterWeekend 💙🤍

Whether you’re with loved ones or taking time for yourself, we hope you find a moment to pause, recharge, and enjoy the break 🐰🌼
#Genome

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🗣️ We can’t keep piloting tech that already works. The NHS needs to scale proven solutions. At #Genome, we deliver real‑time, trusted QA with ward‑to‑board visibility and shared governance, ready to deploy now.
Are we piloting too much and implementing too little?
👉 https://shorturl.at/jFTwF

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Conservation Genomics The rapid decline of global biodiversity represents one of the most pressing challenges of our time, and evolutionary genomic research has a crucial role to pla

A virtual collection @genomebiolevol.bsky.social of articles published in #Genome #Biology & #Evolution that showcase how #molecular and #computational approaches are advancing #conservation biology and improving our understanding and management of #biodiversity academic.oup.com/gbe/pages/co...

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GBE Virtual Collection on Conservation Genomics

Photo credit: Chuya Shinzato

GBE Virtual Collection on Conservation Genomics Photo credit: Chuya Shinzato

Genome Biology and Evolution launches a new virtual collection on "Conservation Genomics"

Read our accompanying Highlight: "Genome Science at the Forefront of Biodiversity's Greatest Challenges"
🔗 buff.ly/qBGcsG7

Access the new virtual collection
🔗 buff.ly/VxXZUKv

#genome #evolution #congen

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Comparative Genomics Provide Insight Into the Evolution of European Aphanomyces euteiches Strains Abstract. Aphanomyces euteiches is an oomycete pathogen causing root rot in pea and other legumes, leading to devastating yield losses in pea production. P

Kälin et al. determined the genome sequences of 68 European Aphanomyces euteiche strains, finding evidence that the southern group is a separate species; virulence-related gene families evolving differently in the Aphanomyces genus were identified.

🔗 doi.org/10.1093/gbe/evag066

#genome #evolution

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💙 The NHS is pushing toward digital‑by‑default care. Most trusts now have strong digital foundations, but real gains will come from better interoperability and usability. At #Genome, we’re helping unlock efficiency and make digital work better for staff and patients 🤝
👉 https://shorturl.at/RYcBw

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GBE | Structural Constraints Acting on the SARS-CoV-2 Spike Protein Reveal Limited Space for Viral Adaptation

GBE | Structural Constraints Acting on the SARS-CoV-2 Spike Protein Reveal Limited Space for Viral Adaptation

Herzig, Magwira & Lovell investigate protein structural constraint in SARS-CoV-2 evolution, suggesting that the SARS-CoV-2 spike protein exhibited limited genomic plasticity following zoonotic transmission into the human population.

🔗 doi.org/10.1093/gbe/evag049

#genome #evolution #sarscov2

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Happy April Fools’ to the teammate who always says:
‘I’ll just do the audit manually, it’ll be quicker.’

We admire the confidence 😇

We’ll stick to tools that save time and sanity, because we all know where manual audits lead… #Genome

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Genome Biology and Evolution | April 2026 cover

Genome Biology and Evolution | April 2026 cover

The April 2026 issue of Genome Biology and Evolution is now live, with our recent article on the genomics of Svalbard reindeer by Dussex et al. on the cover.

🔗 academic.oup.com/gbe/issue/18/4

📷 Brage B. Hansen

#genome #evolution #congen #conservation

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Chromatin organization in Asgard archaea: histones, SMC complexes, and the archaeal roots of eukaryotic chromatin
#microbiology #genetics #genome #chromatin #archaea #eukaryotes #MicroSky
@cp-trendsgenetics.bsky.social
www.sciencedirect.com/science/arti...

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Been working on some of my own figure making and made this little html tool to pull from InterPro API and enhance the sunburst plots. #evolution #taxonomy #biosky #genome #science #protein
www.schiracha.com/taxonomysunb...

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De Novo Chromosome-Level Assembly of the Endangered Pilocarpus Microphyllus Highlights Genomic Resources for Conservation and Sustainable Pilocarpine Extraction Abstract. Pilocarpus microphyllus (jaborandi) is an endangered plant species with significant bioeconomic relevance, as it is the main known source of pilo

Sobreiro, @sibellevilaca.bsky.social A. Vidal et al. present a chromosome-level genome assembly for the jaborandi, an endangered tropical American plant species with significant bioeconomic relevance.

🔗 doi.org/10.1093/gbe/...

#genome #evolution #PlantSky

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From our review now 10 years ago ... the first tick #genome www.frontiersin.org/journals/cel...

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Genomic Exaptation and Regulatory Landscape Shifts as Key Mechanisms Enabling Flatworm Terrestrialization Abstract. Understanding the genomic toolkit that enabled animal terrestrialization, the shift from aquatic to terrestrial habitats, is key to uncovering th

Carbonetto, @rosafernandez.bsky.social et al. explored genetic changes supporting terrestrial adaptation in planarians, identifying a major burst of gene gain preceding the radiation of terrestrial planarians.

🔗 doi.org/10.1093/gbe/...

#genome #evolution

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🧬 Boosting #pathogen detection! A novel #genome mining algorithm finds short identical repeats (IRSs) that amplify multiple #DNA regions—making PCR assays more sensitive, even with low pathogen DNA.
💻 GitHub: https://ow.ly/Beg450Yh2oa
📝 Study: https://ow.ly/kOt550Yh2oc

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GBE | Genome Assemblies of the Daisy Gorteria diffusa Elucidate the Molecular-Genomic Basis of Pollination by Sexual Deception

The image depicts morphotypes (subspecies) and intraspecific hybrids of Gorteria diffusa L., a South African daisy that is pollinated by sexual deception of male bombyliid flies. Between the inflorescences is a graphic representation of the new reference genome assembly of the G. diffusa ‘Springbok’ morphotype (upper left corner), which, together with genomic analysis of hybrid zones, enabled the discovery of structural genomic changes underlying the evolution of plant sexual deception.

GBE | Genome Assemblies of the Daisy Gorteria diffusa Elucidate the Molecular-Genomic Basis of Pollination by Sexual Deception The image depicts morphotypes (subspecies) and intraspecific hybrids of Gorteria diffusa L., a South African daisy that is pollinated by sexual deception of male bombyliid flies. Between the inflorescences is a graphic representation of the new reference genome assembly of the G. diffusa ‘Springbok’ morphotype (upper left corner), which, together with genomic analysis of hybrid zones, enabled the discovery of structural genomic changes underlying the evolution of plant sexual deception.

Kellenberger @joanameier.bsky.social @beverleycubg.bsky.social et al. studied sexual deception in South African daisy, identifying inverted genomic segments that may maintain the distinct identity of some floral forms in secondary contact zones.

🔗 doi.org/10.1093/gbe/evag065

#genome #evolution

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It’s #WorldBackupDay!
In healthcare, protecting data is protecting patients.
At #Genome we build resilient, real‑time systems, because insights only matter when the data behind them is secure.
Back up, stay safe, keep care running. 💙 https://www.worldbackupday.com/en

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Lifespan Predicts Mitochondrial Substitution Rates across Vertebrates, but Methodology Matters Abstract. Why do some species live for mere months, while others persist for centuries? A leading explanation implicates mitochondria. The mitochondrial th

Sterling, Zwonitzer & Havird explored the relationship between mtDNA evolution and species' lifespans, showing long-lived vertebrates showed reduced synonymous and nonsynonymous substitution rates, suggesting lower mtDNA mutation.

🔗 doi.org/10.1093/gbe/...

#genome #evolution #mtDNA

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This square design has a background suggestive of a DNA molecule in green tones. The headline asks, “Is there a little wolf in your Chihuahua?” Farther down it says, “Adventures in Dog Genetics.” Credits: Upper left Wolf: Andrew Spear for the New York Times. Center: Lance of Fran-Jo, ancestor of most US German shepherds. Lower right: a Pomeranian and a Chihuahua mix by Calla Kessler for the New York Times.

This square design has a background suggestive of a DNA molecule in green tones. The headline asks, “Is there a little wolf in your Chihuahua?” Farther down it says, “Adventures in Dog Genetics.” Credits: Upper left Wolf: Andrew Spear for the New York Times. Center: Lance of Fran-Jo, ancestor of most US German shepherds. Lower right: a Pomeranian and a Chihuahua mix by Calla Kessler for the New York Times.

Is there a little wolf in your Chihuahua? Recent #research made possible by all those #dog #genome tests is opening new insights on the changes dogs have undergone since #domestication.
www.nytimes.com/2025/11/24/s...

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How Does Transcription-Associated Mutagenesis Shape tRNA Microevolution? Abstract. Transfer RNAs (tRNAs) are among the most highly conserved and frequently transcribed genes. Recent studies have demonstrated that tRNAs experienc

Baños, @annalisepaaby.bsky.social et al. propose a model of tRNA microevolution driven by transcription-associated mutagenesis (TAM) and demonstrate that the observed secondary structure characteristics align with predicted TAM-biased patterns.

🔗 doi.org/10.1093/gbe/...

#genome #evolution

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GBE | A Deep Dive into the Globin Superfamily of Sharks, Skates, and Rays: Contrasting Patterns of Gene Loss and Retention Relative to Bony Vertebrates

Walt et al. leveraged genomic and transcriptomic datasets to investigate the evolutionary history of the globin gene superfamily in cartilaginous fishes. The illustration depicts representatives from the three major lineages of cartilaginous fishes: the whale shark (top), the giant manta ray (right), and the elephant fish (left). The three cartilaginous fishes are surrounding an illustration of the tertiary structure of a hemoglobin subunit. The illustration was prepared by Amber E. McDonald.

GBE | A Deep Dive into the Globin Superfamily of Sharks, Skates, and Rays: Contrasting Patterns of Gene Loss and Retention Relative to Bony Vertebrates Walt et al. leveraged genomic and transcriptomic datasets to investigate the evolutionary history of the globin gene superfamily in cartilaginous fishes. The illustration depicts representatives from the three major lineages of cartilaginous fishes: the whale shark (top), the giant manta ray (right), and the elephant fish (left). The three cartilaginous fishes are surrounding an illustration of the tertiary structure of a hemoglobin subunit. The illustration was prepared by Amber E. McDonald.

Walt et al. leverage newly available cartilaginous fish genomes to investigate globin gene family evolution, revealing both similar and contrasting patterns of globin gene evolution between cartilaginous and bony vertebrates.

🔗 doi.org/10.1093/gbe/...

🖌️ Amber E. McDonald

#genome #evolution

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Whatever the future
holds in store,
we’ll make sure
you are part of it
#cloning #dna #clones #medical
#human #humanity #Geneticengineering #biotech #Artificalintelligence #futurehumans #fertility #robotics #genetics #genome #elon
#elonmusk

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Inside the stealthy startup that pitched brainless human clones
www.technologyreview.com
#cloning #dna #clones #medical
#human #humanity #Geneticengineering #biotech #Artificalintelligence #futurehumans #fertility #robotics #genetics #genome #elon
#elonmusk

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GBE | Allelic Variation at tRNA Genes in Three Nematode Species Indicates Mutation Load Despite Strong Purifying Selection

Transfer RNAs (tRNAs) are ancient, essential molecules with a consistent ‘cloverleaf’ structure (gray points here), but the genes that encode them vary substantially within populations of nematodes (like the C. elegans worm pictured here). This variation, represented by the pie charts here, has been governed by mutation and natural selection and likely impacts tRNA function.

GBE | Allelic Variation at tRNA Genes in Three Nematode Species Indicates Mutation Load Despite Strong Purifying Selection Transfer RNAs (tRNAs) are ancient, essential molecules with a consistent ‘cloverleaf’ structure (gray points here), but the genes that encode them vary substantially within populations of nematodes (like the C. elegans worm pictured here). This variation, represented by the pie charts here, has been governed by mutation and natural selection and likely impacts tRNA function.

@averydb.bsky.social @annalisepaaby.bsky.social et al. show that cytosolic transfer RNAs genes in three Caenorhabditis nematodes carry signatures of high rates of historical transcription-associated mutagenesis and of purifying selection.

🔗 doi.org/10.1093/gbe/evag053

#genome #evolution

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GBE | The Missing Piece: Functional Telomerase Restored in the Beetle Model

GBE | The Missing Piece: Functional Telomerase Restored in the Beetle Model

Fajkus et al. identify two telomerase RNA paralogs in red flour beetle, confirm their expression, and reconstitute active telomerase in vitro, illuminating the evolutionary plasticity of beetle telomere maintenance.

🔗 doi.org/10.1093/gbe/evag069

#genome #evolution

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Decoding the complete genome of the fungus responsible for Cercospora leaf spot in olive trees Collaboration between the UCO's Agronomy and Genetics departments was key to sequencing the genome of this pathogen, which is responsible for losses of up to €50 million per year. Cercospora leaf…

Decoding the complete #genome of the #fungus responsible for #Cercospora leaf spot in #olive #trees ...

| #fungi | #pathogen | #CercosporaLeafSpot | #Pseudocercospora | Via @sciencex.bsky.social

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GBE | Unraveling the Genome of Epidendrum Fulgens: Demographic History and Gene Family Dynamics in a Resilient Neotropical Orchid

Photo: Fábio Pinheiro

Epidendrum fulgens is an endemic Brazilian orchid species distinguished by its bright orange flowers and its distribution along coastal sand dunes.

GBE | Unraveling the Genome of Epidendrum Fulgens: Demographic History and Gene Family Dynamics in a Resilient Neotropical Orchid Photo: Fábio Pinheiro Epidendrum fulgens is an endemic Brazilian orchid species distinguished by its bright orange flowers and its distribution along coastal sand dunes.

@jacqmattos.bsky.social et al. present the first chromosome-scale assembly from the orchid Epidendrum, and identify two events of population expansion and retraction in E. fulgens demographic history.

🔗 doi.org/10.1093/gbe/evag057

📷 Fábio Pinheiro

#genome #evolution #PlantSky

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Petr Heneberg publishes a new Letter urging caution on the interpretation of evidence linking regulatory processes to eusocial traits in bees.

🔗 doi.org/10.1093/gbe/evag032

#genome #evolution

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Today @ 12pm CT! Dr. Javier Rodriguez-Casariego presents the Monthly Seminar on Physical Genomics: "Epigenetic Mechanisms Of Rapid Environmental Plasticity In Reef-Building Corals", live on Zoom. Join us!

Registration is free, but required at tinyurl.com/2rw8n7bt

#epigenetics #corals #genome

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