Protein language models are revolutinizing protein engineering and design. Our goal is to apply them for #enzyme discovery and design for the degradation of plastic polymers

#PLMs #PlasticDegradation #BIORE2AIRCRAFT #AtracciónTalento

@comunidadmadrid.bsky.social
@icp-csic.bsky.social

The exercise-associated enzyme GPLD1 can mitigate damage in an aging brain. Areas of damage (bright red blotches in this mouse brain) are reduced by about 90% when researchers upregulate the enzyme. Image credit: Villeda lab/University of California, San Francisco.

An #enzyme released during #exercise protects the #brain from #aging and #Alzheimers. In PNAS Journal Club: https://ow.ly/l8i450YyT0N

#liver #GPLD1 #transferrin #dementia

Enzyme to Bring Onyx and Myso Protocols to Canton Network in Major Expansion - Crypto Economy Enzyme will deploy its Onyx and Myso protocols on Canton Network, an institutional network backed by Goldman Sachs and Deutsche Börse.

⚙️ Enzyme expands presence on Canton Network

Enzyme will integrate Onyx and Myso protocols into Canton Network to expand its capabilities in the financial ecosystem.

#Crypto #Enzyme #Canton #Blockchain #DeFi

Long-term Caspase-2 inhibition in liver may increase cancer risk despite short-term benefits A recent study from the University of Adelaide reveals potential long-term risks associated with blocking the enzyme Caspase-2, a strategy previously thought to help treat fatty liver disease. While Caspase-2 inhibitors can reduce fat accumulation in the liver and may offer short-term benefits, researchers found that the absence of this enzyme in genetically modified mice caused abnormal liver cell growth, increased genetic damage, and heightened inflammation. Over time, these changes led to liver scarring and significantly higher rates of liver cancer, particularly in older mice. The findings suggest that Caspase-2 plays a critical role in maintaining liver cell stability and removing damaged cells, challenging the assumption that inhibiting it is universally beneficial. The study emphasizes the need for caution in developing therapies targeting Caspase-2, as short-term improvements in fatty liver disease may come with dangerous long-term consequences, including increased susceptibility to chronic liver inflammation, fibrosis, and hepatocellular carcinoma. This research provides a crucial perspective for drug development and treatment strategies for liver disease, particularly as liver conditions continue to rise globally due to aging populations and metabolic disorders.

Long-term Caspase-2 inhibition in liver may increase cancer risk despite short-term benefits

🤖 IA: It's clickbait ⚠️
👥 Usuarios: It's clickbait ⚠️

#liver #cancer #enzyme

View full AI summary:

We have been granted a key #patent for our CRISPR-BMC genome-editing technology. This patent opens significant potential for the further commercial application of the patented nucleases. Press release: t1p.de/pbgn7 #enzyme #protein #smallmolecules #CRISPR

Original post on onedaymd.com

Lumbrokinase vs Nattokinase vs Serrapeptase: Key Differences, Benefits, Risks & Practical Guide (2026) Lumbrokinase, nattokinase, and serrapeptase are all enzymes that have been studied for the...

#anti #blood #clot #fibrinolytic #enzyme #heart #health #lumbrokinase #nattokinase

Origin | […]

Mit 80 Jahren hat der Körper nur noch 10 % seiner Enzymaktivität – Entzündungen nehmen zu, Schwellungen entstehen.
Was das mit Lymphödemen zu tun hat und wie man gegensteuert, erklärt Dr. med. Hellmut Münch im Interview.


👉 Jetzt lesen: https://qs24.run/lymphstau


#Enzyme #Lymphödem #Gesundheit

Magnolia Fleur's MAGNOLIA Enzymatic Floral Peel

Magnolia

stormsisterspatique.blogspot.com/2026/03/magn...

#Skincare #fleurs #Beauty #stormsiaterspatique #gwp #GiftWithPurchase #exfoliation #Enzyme #magnolia

Cholinestérase de la chatte

La cholinestérase est une enzyme qui dégrade l'acétylcholine, un neurotransmetteur essentiel pour la transmission des signaux nerveux. #Cholinestérase #Enzyme #Neurotransmetteur #Acétylcholine #SignalNerveux

– Comment utiliser le vinaigre pour les tâches ménagères – Wikihow: https://fr.wikihow.com/utiliser-le-vinaigre-pour-les-tâches-ménagères Le vinaigre blanc peut aussi être utilisé à la place de l’adoucissant dans votre machine à laver. Il est très efficace sauf pour les serviettes qu’il rend rêches. – Et si le citron était le meilleur ami de votre maison ? – Batmaid : https://batmaid.ch/blog/fr/nettoyage-maison-avec-des-citrons?utm_source=Returning+clients&utm_campaign=7a44a5fa4d-NL_citron_20nov2018&utm_medium=email&utm_term=0_c2cf3deb26-7a44a5fa4d-570640433 Utiliser des nettoyants probiotiques dans les toilettes permet de bénéficier de leurs enzymes en continu pour éliminer les mauvaises odeurs, mais surtout ces bactéries alliées créent une barrière qui empêche les bactéries pathogènes comme E.Coli de s’installer et nous rendre malades. “Un microbiome riche et florissant agit comme une barrière contre les agents pathogènes envahissants”, écrit Ed Yong dans I contain multitudes. “Lorsque nos vieux amis disparaissent, cette barrière disparaît [et] des espèces plus dangereuses peuvent exploiter les […] vides écologiques”. – Quelle est la différence entre le nettoyage enzymatique et le nettoyage probiotique ?: https://covetrushelp.zendesk.com/hc/fr-be/articles/360017911317-Quelle-est-la-diff%C3%A9rence-entre-le-nettoyage-enzymatique-et-le-nettoyage-probiotique- – Découvrez le cœur d’Enzynov : le procédé enzymatique: https://www.enzynov.fr/a-propos/enzymes – Pourquoi le nettoyage probiotique est essentiel en 2021: https://www.mylene.eu/fr/blog/post/pourquoi-le-nettoyage-probiotique-est-essentiel-en-2021.html – Nettoyant Muc-off: https://muc-off.com/pages/product-initiatives – 4 reasons why Muc-off’s punk powder is the greenest way to clean your bike – Redbull: https://www.redbull.com/gb-en/theredbulletin/muc-off-punk-powder-plastic-free-bike-cleaner – Utilisez un savon d’Alep détachant pour enlever les taches sur les vêtements (plus efficace que les détachants…

Le #confort #écolo, un #modedevie: www.aurianneor.org/lecolo-confo...

#Alep #architecture #art #bio #biologique #bois #eau #compost #température #détachant #écologie #environnement #enzyme #hydrochasse #linge #ménage #nettoyage #panneauxsolaires #probiotique #répulsif #responsable #linge #tondeuse

Enzyme assays for measuring soil microbial activity Soil enzymology has a long history. The earliest report of soil enzymes was by Woods (1899), who determined the activity of oxidizing enzymes and hypothesized that these enzymes occurred in the extrac...

Nuevo capítulo de libro en el que la investigadora Carmen Trasar grupo #IMiSPla @mbgcsic.bsky.social es coautora: "Enzyme assays for measuring soil microbial activity"
@digitalcsic.bsky.social @csicgalicia.bsky.social
#Enzyme #Soil #MicrobialActivity

link.springer.com/chapter/10.1...

New article to read from @upcite.bsky.social! Increased intervals in enzyme replacement therapy for stable type 1 #Gaucher disease.

➡️ Supporting personalized spacing strategies that may improve quality of life and reduce healthcare costs.

🔗 doi.org/10.1111/joim.70079

#lysosomal #enzyme

Invista: Kooperation mit Epoch Biodesign bei Nylon-Recycling renewable-carbon.eu/news/?p=173668 #bionylon #enzyme #kreislaufwirtschaft #künstlicheintelligenz #polyamide6 #recycling #rezyklate #RenewableCarbon

How an exercise-activated enzyme helps to keep the brain young A protein reinforces the blood–brain barrier, which becomes leaky with age.

How an #exercise- activated #enzyme helps to keep the #brain young

www.nature.com/articles/d41...

A bacterium that degrades and assimilates poly(ethylene terephthalate) Two specialized enzymes from a newly isolated bacterium break down plastic into its simplest building blocks. [Also see Perspective by Bornscheuer]

"Some bacteria think plastic is fantastic" The first #enzyme degrading #PET, found in bacteria isolated near a bottle recycling site, is one of our references on the road to complex polymer degradation 👉 shre.ink/Auep #AtracciónTalento @comunidadmadrid.bsky.social #BIORE2AIRCRAFT

Comprehensive new book by Mann et al.:

‘Cutting Edge Technologies for Developing Future Crop Plants’

Fig.13.1

tinyurl.com/y9jha5vt

#WIS

#PlantandEnvironmentalScience

#AntiOxidant

#Oxidation

#Enzyme

#Stress

#OxidativeBurst

Braess’ Paradox in Enzyme Kinetics: Asymmetry from Population Balance without Direct Cooperativity The ATPase ABCE1, a member of the ubiquitous ATP-Binding Cassette protein superfamily, is essential in eukaryotic and archaeal ribosome recycling. It comprises a pair of homologous nucleotide-binding ...

📜 We present our most recent joint publication with Robert and Colin "Braess’ Paradox in Enzyme Kinetics: Asymmetry from Population Balance without Direct Cooperativity" in the Journal of Chemical #Theory and #Computation! #ATPase #enzyme #MarkovModelling 🔗 pubs.acs.org/doi/10.1021/...

Cleveland Researchers Discover Enzyme That Controls Both Weight Gain and Cholesterol Levels in Animal Models New Study from University Hospitals and Case Western Reserve University published in Science Signaling.

Enzyme that controls both weight gain and cholesterol levels discovered [via Cleveland Medical Center] 🧪🥼⚕️🩺

"blocking this nitric oxide-removing enzyme #SCoR2 prevented weight gain and liver injury [and] also lowered bad cholesterol.

news.uhhospitals.org/news-release...

#Obesity #enzyme #disease

#bskyart #surrealism #iconoplasm #AIArt #AIArtist #AIArtwork #AIimages #GenArt #DigitalArt #AIArtGallery #AIGeneratedArt #AIArtCommunity #synthart #sigil #enzyme

Sigil Enzyme 4004

Complex For Simple: Nature's Overkill Engineering

Complex For Simple: Nature's Overkill Engineering

#Catalase #Enzyme #Biochemistry #Protein #Hydrogenperoxide

sciencehumor.io/biology-memes/complex-fo...

From left: Adrian Tripp, Markus Braun and Gustav Oberdorfer from the Institute of Biochemistry at TU Graz as well as Mélanie Hall from the Institute of Chemistry at Uni Graz. Image Source: IBC - TU Graz

Neue KI-Methode revolutioniert das Design von Enzymen renewable-carbon.eu/news/?p=172753 #biokatalysatoren #bioökonomie #biotechnologie #enzyme #kreislaufwirtschaft #künstlicheintelligenz #RenewableCarbon

Wie Mikroben Plastik abbauen und verwerten können renewable-carbon.eu/news/?p=172700 #biorecycling #enzyme #kreislaufwirtschaft #mikroben #pilze #recycling #RenewableCarbon

Researchers say resurrected ancient enzyme could explain early life on Earth and beyond Researchers use synthetic biology to reverse-engineer modern nitrogenases and rebuild their possible ancestors, in an effort to better understand the origins of life on Earth and beyond.

Resurrected ancient #enzyme could explain early #life on #Earth and beyond ...

| #nitrogenases | #astrobiology | #Nitrogen | By @utahstate.bsky.social via eurekalert .org

Original post on sci.news

Biologists ‘Resurrect’ 3.2-Billion-Year-Old Enzyme A team of researchers led by the University of Wisconsin-Madison has reverse-engineered a primordial nitrogen-fixing enzyme, illuminating how ...

#Astrobiology #Biology #Bacteria #Biosignature #DNA #Enzyme […]

[Original post on sci.news]

Original post on sci.news

Biologists ‘Resurrect’ 3.2-Billion-Year-Old Enzyme A team of researchers led by the University of Wisconsin-Madison has reverse-engineered a primordial nitrogen-fixing enzyme, illuminating how ...

#Astrobiology #Biology #Bacteria #Biosignature #DNA #Enzyme […]

[Original post on sci.news]

An evolutionarily diverged CCD4 #enzyme negatively regulates mesocotyl elongation in #rice

A #Letter by Zhang et al.
👇

📖 nph.onlinelibrary.wiley.com/doi/10.1111/...

#LatestIssue

Enzyme Catalysis in Action!
#Enzyme shown here (PDB 7GCH) is #Chymotrypsin from Bos taurus and rendered with the help of @UCSFChimeraX molecular visualization program and Blender 3D software!

#scientificillustration #biochemistry #enzymes #biology #3dmodel #lockandkeymodel

Artikel + Zusammenfassung:

www.reddit.com/r/hanf/comme...

Die Entwicklung von #Cannabinoiden in #Cannabis ist eine #Geschichte der langsamen #Evolution & #Innovation. Durch die Wiederbelebung und Untersuchung antiker #Enzyme haben Wissenschaftler Einsichten in die chemische Entwicklung.

Origins of THC, CBD and CBC in cannabis revealed Wageningen researchers reconstruct millions-of-years-old ‘ancestral enzymes’ from cannabis Reconstruction of extinct ‘ancestral enzymes’ from cannabis opens new avenues for innovative medicinal plants

Researchers discover the origins of THC, CBD, and CBC in Cannabis [via Wageningen U] 🧪🥼🚬🌿🧘

"researchers reconstructed extinct enzymes that were active millions of years ago in ancestors of the cannabis plant"

www.wur.nl/en/news/orig...

#cannabis #marijuana #THC #CBD #CBC #origin #enzyme

What Really Happens Inside Sourdough? Scientists Uncover the Secret Life of Wheat Fibers Sourdough fermentation reshapes wheat fibers through enzyme activity, influencing bread texture, nutrition, and flavor. Bread has been a dietary cornerstone for millennia, and sourdough has recently returned to prominence. Many people value it for its natural image, nutritional profile, and rich taste. Yet the science behind sourdough fermentation remains complex. What changes occur as the [...]