The exercise-associated enzyme GPLD1 can mitigate damage in an aging brain. Areas of damage (bright red blotches in this mouse brain) are reduced by about 90% when researchers upregulate the enzyme. Image credit: Villeda lab/University of California, San Francisco.

An #enzyme released during #exercise protects the #brain from #aging and #Alzheimers. In PNAS Journal Club: https://ow.ly/l8i450YyT0N

#liver #GPLD1 #transferrin #dementia

Transferrin is a drug candidate for the treatment of dry age-related macular degeneration (AMD) - PubMed Dysregulation of iron homeostasis plays a crucial role in retinal diseases, contributing to oxidative stress, inflammation, and ferroptosis, key processes that drive the degeneration of the retinal…

Transferrin supplementation restores iron balance, prevents ferroptosis, and protects retinal cells, implying a novel therapeutic path for dry AMD.
#AMD #Retina #Ophthalmology #Ferroptosis #Transferrin #IronMetabolism #Neuroprotection #CellDeathDisease buff.ly/xt4Anvk

This perspective summarizes practical approaches for diagnosing iron deficiency anemia, highlighting essential tests, underlying pathophysiology, clinical implications, and global contributing factors.
#IJCTM #Iron #anemia #ferritin #transferrin
www.sciltp.com/journals/ijc...