Impact of Baseline BCVA on Outcomes with Aflibercept 8 mg in Patients with DME Aflibercept 8 mg demonstrated comparable visual and anatomic improvements versus 2 mg in patients with diabetic macular edema at week 96, regardless of baseline best-corrected visual acuity ≤20/50 versus ≥20/40.

Ophthopedia Update: Impact of Baseline BCVA on Outcomes with Aflibercept 8 mg in Patients with DME: Aflibercept 8 mg demonstrated comparable visual and anatomic improvements versus 2 mg in patients with diabetic macular edema at week 96, regardless of baseline… #Ophthalmology #Retina #Ophthotwitter

🌍 This gives researchers worldwide a powerful starting point to develop therapies to preserve vision.

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Maculopathy in Paclitaxel Users: Nationwide Drug Use, Incidence, and Risk Factors To determine the real-world incidence and risk factors for maculopathy among new paclitaxel users in South Korea.

Ophthopedia Update: Maculopathy in Paclitaxel Users: Nationwide Drug Use, Incidence, and Risk Factors: To determine the real-world incidence and risk factors for maculopathy among new paclitaxel users in South Korea. #Ophthalmology #Retina #Ophthotwitter

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Proliferative Vitreoretinopathy Exhibiting Metaplastic Pseudovascular Morphology A 54-year-old patient presented with light perception vision after a right open-globe repair. B-scan ultrasonography demonstrated an open-funnel retinal detachment. Vitrectomy revealed grade C proliferative vitreoretinopathy. Preretinal membranes were peeled, followed by 360° retinectomy. Inverting the retina revealed a circinate, vascularized-appearing subretinal membrane; histopathology revealed a proliferation of spindled, mesenchymal-transformed appearing retinal pigment epithelial cells, immunohistochemically pancytokeratin positive (A, B).

Ophthopedia Update: Proliferative Vitreoretinopathy Exhibiting Metaplastic Pseudovascular Morphology: A 54-year-old patient presented with light perception vision after a right open-globe repair. B-scan ultrasonography demonstrated an open-funnel retinal… #Ophthalmology #Retina #Ophthotwitter

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Cataract Progression and Risk Factors for Cataract Surgery after Pars Plana Vitrectomy in Phakic Eyes – an IRIS® Registry Analysis To investigate the probability of cataract surgery after pars plana vitrectomy (PPV) in phakic eyes using the IRIS® Registry (Intelligent Research in Sight), and to identify risk factors for subsequent cataract surgery.

Ophthopedia Update: Cataract Progression and Risk Factors for Cataract Surgery after Pars Plana Vitrectomy in Phakic Eyes – an IRIS® Registry Analysis: To investigate the probability of cataract surgery after pars plana vitrectomy (PPV) in phakic eyes using… #Ophthalmology #Retina #Ophthotwitter

Rapid-Onset Choroidal Neovascularization following Welding Arc Injury A 26-year-old welder presented with sudden, progressive vision loss in the right eye (OD) after a welding arc injury. Near-infrared imaging 12 days postinjury showed ring-shaped foveal hyperreflectance surrounded by hyporeflectivity OD and foveolar hyperreflectivity in the left eye (A, B). Spectral-domain OCT revealed central subretinal hyperreflective material and surrounding subretinal fluid OD, whereas the left eye showed focal ellipsoid line disruption (C, D). OCT angiography confirmed a choroidal neovascular membrane OD (E).

Ophthopedia Update: Rapid-Onset Choroidal Neovascularization following Welding Arc Injury: A 26-year-old welder presented with sudden, progressive vision loss in the right eye (OD) after a welding arc injury. Near-infrared imaging 12 days postinjury showed… #Ophthalmology #Retina #Ophthotwitter

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Timing and Determinants of Post-Injection Endophthalmitis After First-Time Anti-VEGF Administration: A Retrospective National Study in the American Academy of Ophthalmology IRIS® Registry (Intelligent Research in Sight) To investigate the epidemiology of post-injection endophthalmitis (PIE) after first anti-VEGF administration and evaluate the association of sociodemographic and clinical factors with incidence, timing of onset, and presenting visual acuity (VA) using the IRIS® Registry (Intelligent Research in Sight).

Ophthopedia Update: Timing and Determinants of Post-Injection Endophthalmitis After First-Time Anti-VEGF Administration: A Retrospective National Study in the American Academy of Ophthalmology IRIS® Registry (Intelligent Research in Sight): To investigate the… #Ophthalmology #Retina #Ophthotwitter

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Some papers stand out from the rest. After Evelyne's passing, we all felt a strong desire to complete this project in her honour. It's more than just a paper; it's a tribute to her memory and her passion for retinal wave
#retina #microglia #retinalwaves #development

www.biorxiv.org/content/10.6...

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Phacovitrectomy versus vitrectomy for primary rhegmatogenous retinal detachment in phakic eyes: a multicentre propensity-matched study To compare anatomical and visual outcomes of pars plana vitrectomy (PPV) versus phacovitrectomy for primary rhegmatogenous retinal detachment (RRD) repair in phakic eyes using a large multicentre database.

Ophthopedia Update: Phacovitrectomy versus vitrectomy for primary rhegmatogenous retinal detachment in phakic eyes: a multicentre propensity-matched study: To compare anatomical and visual outcomes of pars plana vitrectomy (PPV) versus phacovitrectomy for… #Ophthalmology #Retina #Ophthotwitter

Stroke Risk After Ischemic Ocular Events: A Real-World Study of an Electronic Health Record Database Acute ischemic ocular events (IOEs), including retinal artery occlusion (RAO) and amaurosis fugax, pose significant risk for impending ischemic stroke (IS) or transient ischemic attack (TIA). The objective is to investigate clinical characteristics that impact IS/TIA risk following the first RAO or amaurosis fugax among adult patients.

Ophthopedia Update: Stroke Risk After Ischemic Ocular Events: A Real-World Study of an Electronic Health Record Database: Acute ischemic ocular events (IOEs), including retinal artery occlusion (RAO) and amaurosis fugax, pose significant risk for impending… #Ophthalmology #Retina #Ophthotwitter

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#immunofluorescenceassay #staining #retina

Este suplemento puede evitar el deterioro de la retina producto del envejecimiento Un nuevo estudio investigó los efectos de la planta Centella asiatica por sus propiedades antioxidantes, antiinflamatorias y citoprotectoras ...

Este #suplemento puede evitar el deterioro de la #retina producto del envejecimiento

Retinal Astrocytic Hamartoma Complicated by a Branch Retinal Vein Occlusion with Secondary Preretinal Neovascularization A 39-year-old patient was referred for an asymptomatic retinal lesion in the left eye. Fundus examination (A) revealed a well-circumscribed, whitish intraretinal mass located along the inferior temporal arcade (white arrow), associated with adjacent preretinal neovascularization (green arrow). Autofluorescence imaging (B) showed a homogeneous, round, hyperautofluorescent lesion, with a raspberry-like heterogeneous intraretinal mass on OCT B-scan (D). Fluorescein angiography (C) revealed homogeneous staining of the lesion, inferior temporal retinal ischemia, and preretinal neovascularization, suggesting a branch retinal vein occlusion secondary to a mechanical mass effect.

Ophthopedia Update: Retinal Astrocytic Hamartoma Complicated by a Branch Retinal Vein Occlusion with Secondary Preretinal Neovascularization: A 39-year-old patient was referred for an asymptomatic retinal lesion in the left eye. Fundus examination (A) revealed… #Ophthalmology #Retina #Ophthotwitter

PULSAR: Clinical Outcomes of Aflibercept 8 mg with Extended Dosing and 2 mg in nAMD in Subgroups Defined by Baseline Characteristics To evaluate the impact of baseline disease severity on clinical outcomes with aflibercept 8 mg with extended dosing intervals versus aflibercept 2 mg in patients with treatment-naïve neovascular age-related macular degeneration (nAMD).

Ophthopedia Update: PULSAR: Clinical Outcomes of Aflibercept 8 mg with Extended Dosing and 2 mg in nAMD in Subgroups Defined by Baseline Characteristics: To evaluate the impact of baseline disease severity on clinical outcomes with aflibercept 8 mg with… #Ophthalmology #Retina #Ophthotwitter

Hyperreflective Retinal Nerve Fiber Layer Lesion with Neovascularization A 27-year-old woman presented with a 2-week history of blurred vision in the left eye. Best-corrected visual acuity was 20/12.5. Fundus examination showed an inferotemporal whitish lesion (A). Ultra-widefield fluorescein angiography demonstrated early hyperfluorescence of retinal neovascularization and late perivenular fernlike leakage with cystoid macular edema (B). OCT revealed a thickened, hyperreflective lesion confined to the retinal nerve fiber layer (C), with corresponding hyperreflectivity and neovascular flow signal on OCT angiography (D).

Ophthopedia Update: Hyperreflective Retinal Nerve Fiber Layer Lesion with Neovascularization: A 27-year-old woman presented with a 2-week history of blurred vision in the left eye. Best-corrected visual acuity was 20/12.5. Fundus examination showed an… #Ophthalmology #Retina #Ophthotwitter

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