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12 minutes ago

Validation of the “FIRST-ROP” Algorithm at a Neonatal Intensive Care Unit Tertiary Center over Three Decades To validate the FIRST-ROP algorithm in a medium-risk cohort of infants undergoing screening for retinopathy of prematurity (ROP).

Ophthopedia Update: Validation of the “FIRST-ROP” Algorithm at a Neonatal Intensive Care Unit Tertiary Center over Three Decades: To validate the FIRST-ROP algorithm in a medium-risk cohort of infants undergoing screening for retinopathy of prematurity (ROP). #Ophthalmology #Ophthotwitter #Scicomm

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Ophthopedia

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6 hours ago

Reference Standard for Validation of Age-Related Macular Degeneration Screening Algorithms Artificial intelligence (AI)-based screening models hold promise for identifying individuals with undiagnosed age-related macular degeneration (AMD) in non-specialist settings. A standardized reference framework for image labeling is needed to enable consistent training, validation, and deployment of AI based screening algorithms.The goal of the present study is to establish expert consensus on image -based reference standard for labeling AMD

Ophthopedia Update: Reference Standard for Validation of Age-Related Macular Degeneration Screening Algorithms: Artificial intelligence (AI)-based screening models hold promise for identifying individuals with undiagnosed age-related macular degeneration… #Ophthalmology #ophthotwitter #eyecare

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Ophthopedia

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13 hours ago

| OPTH | Dove Medical Press To understand the efficiency, safety, and patient acceptability of using an artificial intelligence-based conversational agent Dora R2 in the cataract pathway.

Ophthopedia Update: Evaluation of Routine Clinical Deployment of an Autonomous Artificial Intelligence Assistant for Cataract Follow-Up in the National Health Service #Ophthomology #Eye #Ophthotwitter

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Ophthopedia

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13 hours ago

Remission in sarcoid uveitis: identification of predictive factors Objective To identify predictive factors of remission in patients with sarcoid uveitis and to evaluate recurrence rates and patterns following remission.Methods Multicentre retrospective study of patients with sarcoid uveitis and a minimum follow-up of 3 years. Remission was defined as the absence of clinical symptoms of sarcoidosis for at least 3 years without treatment. Remission-free Kaplan-Meier survival curves were constructed for selected variables. Cox proportional hazards model was then applied. HRs and 95% CIs were estimated for each variable. Statistical significance was set at the p

Ophthopedia Update: Remission in sarcoid uveitis: identification of predictive factors: Objective

To identify predictive factors of remission in patients with sarcoid uveitis and to evaluate recurrence rates and patterns following remission.Methods

Multicentre… #Ophthalmology #Ophthotwitter #BJO

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Ophthopedia

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13 hours ago

Socioeconomic status, cardiovascular health and joint associations with incident cataract: a prospective study from UK Biobank Aims To investigate the interaction and combined effects of cardiovascular health (CVH) and socioeconomic status (SES) on incident cataract risk.Methods This prospective cohort study included 236 248 UK Biobank participants free of cataract at baseline and with complete data on SES and CVH. Incident cataract was ascertained through hospital inpatient and self-reported records. SES was derived from household income, employment and education using latent class analysis, while CVH was assessed via the Life’s Essential 8 (LE8) score. Cataract risk was evaluated using multivariable Cox regression, with interaction and joint effects analyses performed to assess the interplay between SES and CVH.Results This analysis involved 236 248 participants with an average age of 55.5 years (range: 38–73); 51.6% were female and 95.6% were of white ethnicity. Over a median follow-up period of 11.7 years, 26 791 participants (11.3%) developed cataract. Compared with the high SES group, participants with low SES had a significantly higher risk of cataract (HR, 1.30; 95% CI 1.25 to 1.35). Significant additive and multiplicative interactions between SES and CVH on cataract risk were observed. Better CVH substantially mitigated the adverse association of low SES with cataract. Notably, individuals with low SES and poor CVH showed the highest cataract risk (HR, 1.74; 95% CI 1.57 to 1.93) in contrast to those with high SES and optimal CVH.Conclusions Implementing interventions aimed at enhancing both SES and CVH may prove beneficial in preventing or delaying cataract onset. Adhering to the LE8 guidelines to maintain optimal CVH has the potential to alleviate a significant portion of the excess cataract risk associated with socioeconomic disadvantage.

Ophthopedia Update: Socioeconomic status, cardiovascular health and joint associations with incident cataract: a prospective study from UK Biobank: Aims

To investigate the interaction and combined effects of cardiovascular health (CVH) and socioeconomic status… #Ophthalmology #Ophthotwitter #BJO

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Ophthopedia

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13 hours ago

Trends in incidence and survival for uveal melanoma in Norway, 1993-2021 Background/aims Understanding uveal melanoma incidence and survival trends is crucial for improving patient outcomes and allocating healthcare resources. We aimed to investigate the incidence and survival for uveal melanoma in Norway, 1993–2021, including information on tumour site, tumour (T) category and summary stage.Methods The Cancer Registry of Norway provided data on all patients diagnosed with a first primary uveal melanoma in Norway between 1 January 1993 and 31 December 2021. We calculated age-standardised incidence rates using the European standard population and estimated net survival and crude probability of death. Net survival estimates were obtained using the Pohar-Perme estimator, period approach and cohort approach.Results Altogether, 1497 patients (49.6% men) were diagnosed with a primary uveal melanoma in 1993–2021. The age-standardised incidence rate increased from 6.8 (95% CI 5.7 to 7.9) per million person-years in 1993–1997 to 9.8 (95% CI 8.8 to 11.0) per million person-years in 2017–2021, with an overall rate of 9.0 (95% CI 8.6 to 9.5). This increase was primarily driven by localised, T1 and T2 choroidal melanomas. Ten-year net survival for patients with uveal melanoma remained relatively stable between 57.2% (95% CI 36.2% to 73.5%) in 1993–1997 and 65.5% (95% CI 53.8% to 74.9%) in 2017–2021. Over the same periods, there was a notable net survival improvement in patients with choroidal melanoma from 53.4% (95% CI 27.9% to 73.4%) to 74.8% (95% CI 59.8% to 84.9%).Conclusion The increased uveal melanoma incidence in Norway was mainly due to localised choroidal tumours. Improved detection of choroidal tumours is likely to have contributed to both the increased incidence and long-term net survival, highlighting the potential benefits of early detection strategies.

Ophthopedia Update: Trends in incidence and survival for uveal melanoma in Norway, 1993-2021: Background/aims

Understanding uveal melanoma incidence and survival trends is crucial for improving patient outcomes and allocating healthcare resources. We aimed to… #Ophthalmology #Ophthotwitter #BJO

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Ophthopedia

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13 hours ago

Prevention of endophthalmitis with cataract surgery: where are we now 20 years after the ESCRS Study? Acute postoperative endophthalmitis in cataract surgery, while rare, occurs despite efforts at prevention. Risk factors include host-related characteristics and technique-related aspects. The ocular surface plays a pivotal role, with external microbial flora serving as a pervasive potential source of organisms for infection. Innate natural defence mechanisms are capable of protecting against infection, despite evidence of microbial contamination, with organisms recovered from aqueous humour even in uncomplicated cataract surgeries. With acute endophthalmitis after cataract surgery, coagulase-negative Staphylococci species are the most commonly recovered organisms, followed by other Gram-positive organisms and, less frequently, Gram-negative organisms. Strategies to prevent infection aim to limit organisms entering the eye by reducing organisms on the ocular surface, preventing intraoperative intraocular bacterial contamination and preventing postoperative bacterial contamination with watertight wound closure. Secondary strategies target the eradication of organisms that (despite all precautions) might have entered the eye, including intracameral antibiotic administration. Topical ophthalmic antisepsis with administration of povidone-iodine reduces the clinical occurrence of endophthalmitis with cataract procedures. Evidence demonstrates similar low rates of postoperative endophthalmitis after cataract surgery using standardised preoperative preparation alone, with or without intracameral antibiotic administration, in routine, uncomplicated cases. Stratification of risk guides possible adjunctive intracameral antibiotic administration in addition to standardised prevention practices, with individuals at higher risk, including those undergoing same-day bilateral surgery or with complicated and combined procedures.

Ophthopedia Update: Prevention of endophthalmitis with cataract surgery: where are we now 20 years after the ESCRS Study?: Acute postoperative endophthalmitis in cataract surgery, while rare, occurs despite efforts at prevention. Risk factors include host-related… #Ophthalmology #Ophthotwitter #BJO

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Ophthopedia

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17 hours ago

| OPTH | Dove Medical Press Evaluating preoperative macular OCT provides additional predictive information for early postoperative visual acuity after phacoemulsification cataract surgery

Ophthopedia Update: Incremental Predictive Value of Preoperative Macular Optical Coherence Tomography for Postoperative Visual Acuity After Phacoemulsification Cataract Surgery: A Retrospective Cohort Study #Ophthomology #Eye #Ophthotwitter

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Ophthopedia

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17 hours ago

Retraction Note: Ultrasound biomicroscopy qualitative and quantitative signs of phacoantigenic uveitis Eye, Published online: 16 April 2026; doi:10.1038/s41433-026-04458-5Retraction Note: Ultrasound biomicroscopy qualitative and quantitative signs of phacoantigenic uveitis

Ophthopedia Update: Retraction Note: Ultrasound biomicroscopy qualitative and quantitative signs of phacoantigenic uveitis: Eye, Published online: 16 April 2026; doi:10.1038/s41433-026-04458-5Retraction Note: Ultrasound biomicroscopy qualitative and quantitative… #Ophthalmology #Eye #Ophthotwitter

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Ophthopedia

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21 hours ago

| OPTH | Dove Medical Press Assessing pediatric patients aged

Ophthopedia Update: Spectrum of Pediatric Visual Disorders in Outpatient and Inpatient Settings at a Tertiary Hospital: A 10-Year Retrospective Study #Ophthomology #Eye #Ophthotwitter

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Ophthopedia

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23 hours ago

Reply We thank Adelekan-Kamara et al. for their thoughtful comments on the association of age and socioeconomic status with visual axis opacification (VAO) following pediatric cataract surgery and welcome the opportunity to further discuss the important points raised.

Ophthopedia Update: Reply: We thank Adelekan-Kamara et al. for their thoughtful comments on the association of age and socioeconomic status with visual axis opacification (VAO) following pediatric cataract surgery and welcome the opportunity to further… #Ophthalmology #ophthotwitter #eyecare

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Ophthopedia

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23 hours ago

Re Lee et al.:Visual Axis Opacification after Pediatric Cataract Surgery in the IRIS® Registry (Intelligent Research in Sight) (Ophthalmology. 2025;132:1317–9) We read with interest the recent report by Lee et al utilising selective administrative health data in a retrospective study of outcomes following cataract surgery in children and young people aged under 19 years.1 Lee et al described an increased risk of visual axis opacification (VAO) in those with a history of trauma, uveitis and retinitis of prematurity. The investigators also explored associations with age, ocular comorbidity, ethnicity and insurance status, using the latter as a marker of socioeconomic status.

Ophthopedia Update: Re Lee et al.:Visual Axis Opacification after Pediatric Cataract Surgery in the IRIS® Registry (Intelligent Research in Sight) (Ophthalmology. 2025;132:1317–9): We read with interest the recent report by Lee et al utilising selective… #Ophthalmology #ophthotwitter #eyecare

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Ophthopedia

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1 day ago

Association of Deep Optic Nerve Head Structural Remodeling with Choroidal Microvasculature Dropout in Glaucoma with and without Myopia To evaluate associations between parapapillary choriocapillaris microvascular dropout (MvD) and optical coherence tomography (OCT)-detected deep optic nerve head (ONH) structures in glaucomatous eyes with and without myopia.

Ophthopedia Update: Association of Deep Optic Nerve Head Structural Remodeling with Choroidal Microvasculature Dropout in Glaucoma with and without Myopia: To evaluate associations between parapapillary choriocapillaris microvascular dropout (MvD) and optical… #Ophthalmology #Ophthotwitter #Scicomm

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Ophthopedia

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1 day ago

| OPTH | Dove Medical Press This study evaluated the effectiveness of intraoperative 9-0 nylon thread insertion (NTI) technique in preventing hypotony-related complications.

Ophthopedia Update: Efficacy of Intraoperative 9-0 Nylon Thread Insertion for Preventing Hypotony-Related Complications Following PreserFlo MicroShunt Implantation in Japanese Patients: A Comparative Study #Ophthomology #Eye #Ophthotwitter

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Ophthopedia

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1 day ago

| OPTH | Dove Medical Press The dual-pathway inhibition VEGF-A Ang-2 achieved rapid hemorrhage clearance and meaningful vision gains, offering clinical hope for this high-risk population

Ophthopedia Update: Visual and Anatomic Outcomes of Faricimab in Naïve Neovascular Age-Related Macular Degeneration with Subretinal Hemorrhage: A Multi-Centre Retrospective Analysis #Ophthomology #Eye #Ophthotwitter

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Ophthopedia

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1 day ago

Quantitative aqueous PCR viral load predicts poor visual outcome in acute retinal necrosis Background/aims Acute retinal necrosis (ARN) is a rare herpetic uveoretinitis that frequently results in severe vision loss. Evidence from large single-centre cohorts remains limited. We evaluated clinical characteristics and prognostic factors in 148 ARN cases.Methods We retrospectively reviewed 148 consecutive patients with ARN treated at a tertiary referral centre (1985–2021). Causative virus and aqueous viral DNA copy number at presentation were determined by PCR. Associations of final best-corrected visual acuity (BCVA, logMAR) with aqueous viral load, timing of antiviral initiation and extent of retinal necrosis (quadrants involved) were analysed. Quantitative aqueous viral-load data were available in 73 of 148 patients.Results Varicella-zoster virus accounted for 125/148 (84.5%) cases; herpes simplex virus (HSV-1) for 16 (10.8%) and HSV-2 for 7 (4.7%). Mean age at onset was 50.8 years. Mean interval from symptom onset to antiviral initiation was 11.5±7.0 days; median interval from onset to vitrectomy was 22 days. Mean BCVA worsened from 0.71 logMAR at presentation to 1.20 logMAR at final visit (p

Ophthopedia Update: Quantitative aqueous PCR viral load predicts poor visual outcome in acute retinal necrosis: Background/aims

Acute retinal necrosis (ARN) is a rare herpetic uveoretinitis that frequently results in severe vision loss. Evidence from large… #Ophthalmology #Ophthotwitter #BJO

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Ophthopedia

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1 day ago

Deep learning in population-based screening for glaucoma Background/aims Deep learning algorithms have shown promise for glaucoma detection using retinal imaging. The Northern Finland Birth Cohort Eye Study is a randomised prospective cohort designed to evaluate the efficacy and cost-effectiveness of glaucoma screening in a middle-aged population. This study assessed the performance and generalisability of G-RISK, a deep learning model for glaucoma screening from fundus images, in individuals aged 45–49 years with low glaucoma prevalence (1.1%).Methods Four screening scenarios were evaluated: detection of (1) glaucoma eyes, (2) glaucoma patients, (3) glaucoma and glaucoma suspect eyes and (4) glaucoma and glaucoma suspect patients. Performance across four photographic modalities was assessed using the area under the receiver operating characteristic curve (AUC), the precision–recall AUC (PR-AUC), and sensitivity at 95% specificity.Results G-RISK achieved its highest performance when screening for glaucoma eyes using colour fundus photographs, with an AUC of 0.83 (95% CI 0.75 to 0.90), PR-AUC of 0.16 (95% CI 0.05 to 0.28) and sensitivity at 95% specificity of 0.43 (95% CI 0.28 to 0.59). Furthermore, discrimination remained consistent across other modalities (AUC 0.75–0.78). Performance was higher for confirmed glaucoma than combined glaucoma and glaucoma suspect cases (AUC 0.83 vs 0.67).Conclusions G-RISK achieved the best results on colour fundus images, while maintaining discrimination across other imaging modalities. Screening metrics were constrained by the relatively young age and low glaucoma prevalence of the cohort. The reduced performance observed when including glaucoma suspects may relate to variability and uncertainty in their clinical definition.

Ophthopedia Update: Deep learning in population-based screening for glaucoma: Background/aims

Deep learning algorithms have shown promise for glaucoma detection using retinal imaging. The Northern Finland Birth Cohort Eye Study is a randomised prospective cohort… #Ophthalmology #Ophthotwitter #BJO

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Ophthopedia

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1 day ago

Real-world effect of vitrectomy combined with intravitreal conbercept for treatment of vitreous haemorrhage in proliferative diabetic retinopathy (QILIN I): a prospective cohort study Aims To evaluate the efficacy of intravitreal conbercept (IVC) combined with pars-plana vitrectomy (PPV) for severe, non-clearing vitreous haemorrhage (VH) caused by proliferative diabetic retinopathy (PDR) in real-world practice.Methods This prospective, observational, multicentre, cohort study enrolled 523 patients with VH due to PDR at 26 hospitals from August 2022 to June 2024. Patients were treated with preoperative IVC (3–7 days prior to PPV), intraoperative IVC (at completion of PPV) and PPV alone as control. The primary outcome was the incidence of early (7–30 days) postoperative VH (POVH). Secondary outcomes included late POVH (30–180 days), postoperative best-corrected visual acuity (BCVA) and distribution of POVH severity.Results Of 425 participants (425 eyes) finally enrolled, 406 completed 30-day-visit, and 341 completed 180-day-visit. The incidence of early POVH was 24.0% (36 of 150) in preoperative IVC versus 23.2% (33 of 142) intraoperative IVC compared with 37.6% (50 of 133) in control (p=0.0160, 0.0122). The incidence of late POVH was 11.9% (16 of 134) in preoperative IVC versus 17.5% (20 of 114) intraoperative IVC versus 17.8% (19 of 107) in control (p=0.4109, 0.4661). The early POVH was less severe in preoperative and intraoperative IVC cohorts compared with control (p=0.0067, 0.0304), while the severity of late POVH was comparable (p=0.4860, 0.8353). Mean postoperative BCVA was all improved but showed no significant intergroup differences (p>0.05).Conclusions This study, with the largest participants to date, demonstrates that IVC administered preoperatively or intraoperatively effectively reduces early POVH incidence, rather than late POVH. Preoperative IVC may be preferable for patients with more severe baseline disease characteristics.

Ophthopedia Update: Real-world effect of vitrectomy combined with intravitreal conbercept for treatment of vitreous haemorrhage in proliferative diabetic retinopathy (QILIN I): a prospective cohort study: Aims

To evaluate the efficacy of intravitreal conbercept… #Ophthalmology #Ophthotwitter #BJO

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Ophthopedia

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1 day ago

Effect of intraocular pressure-lowering agents in highly myopic eyes Background/Aims To evaluate the effects of intraocular pressure (IOP)-lowering agents in highly myopic eyes.Methods Highly myopic patients with axial length (AL) data for longer than 5 years were included. The changes in IOP, AL and myopic macular complications during the study period were compared between the eyes treated with IOP-lowering agents (treatment group) and those never treated (control group).Results The treatment (30 eyes of 30 patients) and control (90 eyes of 90 patients) groups had comparable baseline characteristics except for IOP, which was significantly higher in the treatment group (p=0.020). During the study period, the treatment group showed a greater mean percentage decrease in IOP per year compared with the control group (–2.13±2.51% /year vs+0.30 ± 2.31% /year; p

Ophthopedia Update: Effect of intraocular pressure-lowering agents in highly myopic eyes: Background/Aims

To evaluate the effects of intraocular pressure (IOP)-lowering agents in highly myopic eyes.Methods

Highly myopic patients with axial length (AL) data for… #Ophthalmology #Ophthotwitter #BJO

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Ophthopedia

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1 day ago

Optic nerve intraneural pressure trend under intraocular-intracranial pressure effects The imbalance between intraocular pressure (IOP) and intracranial pressure (ICP) is a recognised contributor to optic nerve (ON) injury. Clinically, the translaminar pressure difference is often simplistically interpreted as the direct subtraction of ON cerebrospinal fluid pressure (ON – CSFp) from IOP. While finite element analyses suggest that the transition between these two pressure compartments is neither abrupt nor uniform, instead forming a spatially graded finite transition zone, this concept remains unconfirmed from a fluid dynamics perspective. Given the inability to directly measure intraneural pressure in vivo, we modelled the ON as a continuous fluid medium. Using a mathematical approach, we visually illustrate how IOP and ON–CSFp interact to generate spatially varying intraneural hydrostatic pressure gradients. Our results show that these gradients assume a three-dimensional conical configuration. Elevation of IOP or reduction of ON–CSFp expands this conical gradient field, contributing to ON injury, whereas elevation of ICP produces an inverted conical gradient. The steepest gradients occur in the peripheral region posterior to the lamina cribrosa, rendering this area most vulnerable to damage. This study challenges the clinical oversimplification that pressure difference is equivalent to a mere subtraction of two values. It thereby improves clinicians’ understanding of the biomechanical mechanisms underlying IOP and ICP imbalance-related ON injury. Importantly, it also highlights the often-overlooked phenomenon of intraneural pressure gradients, extending beyond the conventional focus on the translaminar pressure gradient alone.

Ophthopedia Update: Optic nerve intraneural pressure trend under intraocular-intracranial pressure effects: The imbalance between intraocular pressure (IOP) and intracranial pressure (ICP) is a recognised contributor to optic nerve (ON) injury. Clinically, the… #Ophthalmology #Ophthotwitter #BJO

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1 day ago

Pediatric Macular Hole Outcomes with Surgical and Non-Surgical Management: An IRIS® Registry Study To compare visual outcomes, recovery trajectories, and complication rates between surgical and observational management of pediatric macular hole (PMH) using a large national registry.

Ophthopedia Update: Pediatric Macular Hole Outcomes with Surgical and Non-Surgical Management: An IRIS® Registry Study: To compare visual outcomes, recovery trajectories, and complication rates between surgical and observational management of pediatric macular… #Ophthalmology #Retina #Ophthotwitter

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Ophthopedia

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1 day ago

Comment on: Impact of Phacoemulsification on Vitreomacular Traction Release and Complications We read with great interest the study by Bala et al1 regarding the impact of phacoemulsification on vitreomacular traction (VMT) release. The authors present the largest comparative cohort to date, providing important evidence suggesting that cataract surgery may not significantly influence the rate or timing of VMT release. This study is a significant contribution, as it dispels a common clinical assumption and appropriately shifts our focus toward intrinsic patient factors.

Ophthopedia Update: Comment on: Impact of Phacoemulsification on Vitreomacular Traction Release and Complications: We read with great interest the study by Bala et al1 regarding the impact of phacoemulsification on vitreomacular traction (VMT) release. The… #Ophthalmology #Ophthotwitter #Scicomm

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Ophthopedia

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2 days ago

Table of Contents Login to your account Email/Username Your email address is a required field. E.g., j.smith@mail.com Password Show Your password is a required field. Forgot password? Remember me Don’t have an account? Create a Free Account If you don't remember your password, you can reset it by entering your email address and clicking the Reset Password button. You will then receive an email that contains a secure link for resetting your password Email* If the address matches a valid account an email will be sent to __email__ with instructions for resetting your password Cancel

Ophthopedia Update: Table of Contents #Ophthalmology #Ophthotwitter #Scicomm

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2 days ago

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Ophthopedia Update: Masthead #Ophthalmology #Ophthotwitter #Scicomm

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2 days ago

Editorial Board

Ophthopedia Update: Editorial Board #Ophthalmology #Ophthotwitter #Scicomm

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2 days ago

Safety and Efficiency Reducing Retinopathy of Prematurity Guideline Sensitivity: An External Validation Using a Large US-based Dataset Recent publications have proposed alternative retinopathy of prematurity (ROP) screening guidelines balancing efficiency with safety. We used the 28-hospital ROP CheckⓇ higher-risk, racially diverse database to perform external validation. ROP Check is neonatology/ophthalmology software that combines customizable, guideline-based screening and ophthalmology monitoring of staging ROP examinations and treatment.

Ophthopedia Update: Safety and Efficiency Reducing Retinopathy of Prematurity Guideline Sensitivity: An External Validation Using a Large US-based Dataset: Recent publications have proposed alternative retinopathy of prematurity (ROP) screening guidelines… #Ophthalmology #Ophthotwitter #Scicomm

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Ophthopedia

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2 days ago

Optical Coherence Tomography Radiomics and Machine Learning Enable Accurate Detection of Forme Fruste Keratoconus Keratoconus (KC) is a bilateral progressive corneal thinning disorder that, without timely intervention, can lead to severe visual loss or even blindness.1 With a prevalence of about 1.38 per 1000 individuals, it remains a major indication for corneal transplantation worldwide.2 Early detection is therefore critical, particularly for forme fruste keratoconus (FFKC), the earliest subclinical stage of the disease.3,4 Identifying FFKC is of great importance in refractive surgery candidates, as missed diagnosis is a major cause of postoperative ectasia, and timely recognition may allow early intervention.

Ophthopedia Update: Optical Coherence Tomography Radiomics and Machine Learning Enable Accurate Detection of Forme Fruste Keratoconus: Keratoconus (KC) is a bilateral progressive corneal thinning disorder that, without timely intervention, can lead to severe… #Ophthalmology #Ophthotwitter #Scicomm

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Ophthopedia

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2 days ago

Obstructive sleep apnea and risk of age-related macular degeneration: A systematic review and meta-analysis We evaluated whether obstructive sleep apnea (OSA) is associated with an increased risk of age-related macular degeneration (AMD). The population included adults with and without OSA. Outcomes included overall AMD risk and AMD stage–specific outcomes, including neovascular AMD (nAMD), non-neovascular AMD, late AMD with geographic atrophy (GA), and anti-VEGF therapy requirement.

Ophthopedia Update: Obstructive sleep apnea and risk of age-related macular degeneration: A systematic review and meta-analysis: We evaluated whether obstructive sleep apnea (OSA) is associated with an increased risk of age-related macular degeneration (AMD).… #Ophthalmology #Ophthotwitter #Scicomm

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2 days ago

Prevalence and Associated Features of Reticular Pseudodrusen in Neovascular Age-Related Macular Degeneration in an Asian Population Age-related macular degeneration (AMD) is one of the leading causes of irreversible vision loss among older people.1-3 The number of affected patients is estimated to be 300 million by 2040, threatening patients’ quality of vision in the aging society.4 Drusen, extracellular deposits beneath the retinal pigment epithelium (RPE), are considered the hallmark of AMD.5

Ophthopedia Update: Prevalence and Associated Features of Reticular Pseudodrusen in Neovascular Age-Related Macular Degeneration in an Asian Population: Age-related macular degeneration (AMD) is one of the leading causes of irreversible vision loss among… #Ophthalmology #Ophthotwitter #Scicomm

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2 days ago

The Association Between Diabetic Retinopathy Severity and Dementia Risk: A TriNetX Longitudinal Cohort Study Diabetes mellitus (DM) and diabetic retinopathy (DR) have been associated with higher incidence of dementia and may serve as clinical indicators for underlying cognitive disease. This study investigated whether severity of DR is linked to increased risk of dementia.

Ophthopedia Update: The Association Between Diabetic Retinopathy Severity and Dementia Risk: A TriNetX Longitudinal Cohort Study: Diabetes mellitus (DM) and diabetic retinopathy (DR) have been associated with higher incidence of dementia and may serve as… #Ophthalmology #Ophthotwitter #Scicomm

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