Braess’ Paradox in Enzyme Kinetics: Asymmetry from Population Balance without Direct Cooperativity The ATPase ABCE1, a member of the ubiquitous ATP-Binding Cassette protein superfamily, is essential in eukaryotic and archaeal ribosome recycling. It comprises a pair of homologous nucleotide-binding ...

📜 We present our most recent joint publication with Robert and Colin "Braess’ Paradox in Enzyme Kinetics: Asymmetry from Population Balance without Direct Cooperativity" in the Journal of Chemical #Theory and #Computation! #ATPase #enzyme #MarkovModelling 🔗 pubs.acs.org/doi/10.1021/...

Structural modeling and biochemical characterization of MSMEG_0748, a MoxR ATPase from Mycobacterium smegmatis. Computational and Structural Biotechnology Journal, DOI: https://doi.org/10.1016/j.csbj.2025.11.010

🔗 Structural modeling and biochemical characterization of MSMEG_0748, a MoxR ATPase from Mycobacterium smegmatis. Computational and Structural Biotechnology Journal, DOI: doi.org/10.1016/j.cs...

📚 CSBJ: www.csbj.org

#Mycobacterium #ATPase #AlphaFold #StructuralBiology #Biophysics #Microbiology

Advance your kinase and ATPase research.

The ADP-Glo™ Max Assay offers sensitive luminescent detection of ATPase and kinase activity, even at ATP concentrations up to 5mM, delivering reliable IC₅₀ values without radioactivity.

More info at: https://tinyurl.com/ADPGlo 

#KinaseResearch #ATPase

Lipid-Protein Interplay: How the Plant Plasma Membrane H-ATPase Dynamically Interacts with Its Lipid Environment - A Review - Premier Science Keywords: H+-atpase regulation, Lipid-protein interactions, Plant plasma membrane, Sterol influence, Sphingolipid role.

doi.org/10.70389/PJP...

#lipid #protein #plant #plasmamembrane #atpase

Braess' Paradox in Enzyme Kinetics: Asymmetry from Population Balance without Direct Cooperativity The ATPase ABCE1, a member of the ubiquitous ATP-Binding Cassette protein superfamily, is essential in eukaryotic and archaeal ribosome recycling. It comprises a pair of homologous nucleotide-binding ...

📝 We proudly present our most recent preprint @biorxiv-biophys.bsky.social about Braess' Paradox in #Enzyme Kinetics: Asymmetry from Population Balance without Direct Cooperativity with Colin and Robert 🤝 #ATPase #ABCE1 #MarkovModel #allostery📜Happy reading: www.biorxiv.org/content/10.1...

Here you can see a cryoEM structure of one of the intermediates of the Cdc48 AAA+ ATPase protein unfolding pathway (PDB code: 8UA1)

Rendering by Francisco J. Enguita made with #ProteinImager

3dproteinimaging.com/protein-imag...

#SciArt #molecularart #atpase #aaa #unfolding

Molecular Tweezers Block the Functional Pore of a Protein Machine We present symmetric multivalent tweezers as the first class of supramolecular elements designed to cover and functionally block a protein pore. As a model, we chose the enzyme p97, a hexameric AAA-AT...

New Paper out in @jacs.acspublications.org ! 🧪 The Schrader Lab developed multivalent tweezers that symmetrically block the pore of #ATPase #p97, inhibiting substrate unfolding. A new supramolecular approach to target protein machines. doi.org/10.1021/jacs...
#SupramolecularChemistry #Tweezers