Epigentics Update - Distinctive DNA sequence features define epigenetic longevity of inflammatory memory bit.ly/4bBbd5l
thefuchslab.bsky.social in Science
#Epigenetics #Psoriasis #DNAm #Inflammation
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Epigenetics Update - Cell-type-specific transposon demethylation and TAD remodeling in aging mouse brain bit.ly/46UPsdZ
M. Margarita Behrens and Joseph R. Ecker (Salk) reporting in Cell
#Epigenetics #DNAm #Chromatin #ChromatinConformation #Aging
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Epigenetics Update - Photorespiration is linked to DNA methylation by formate as a one-carbon source go.nature.com/4aPmjSs
Martin Groth (Helmholtz Munich) reporting in Nat Plants
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Epigenetics Update - Nucleosome spacing regulates linker methylation by DNMT3A2/3B3 bit.ly/4rugnFA
Evan J. Worden (Van Andel Institute) reporting in Mol Cell
#Epigenetics #DNAm #DNMTs
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Epigenetics Update – A pan-cancer compendium of 1,294 plasma cell-free DNA methylomes and fragmentomes enabling multicancer detection go.nature.com/4qGhUaj
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Epigenetics Update - M-PACT leverages cell-free DNA methylomes to achieve robust classification of pediatric brain tumors go.nature.com/3ZCyugn
Paul A. Northcott reporting in Nat Cancer
#Epigenetics #DNAm #Cancer
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New Epigenome Technologies Blog post! bit.ly/4rfD3JA
"What Can Epigenomic Foundation Models Reveal About Biology?"
Part 2: Modeling DNA Methylation
#EpigenomeTech #Blog #FoundationModels #DNAm
Epigenetics Update - Chromatin binding and N-terminal domains of DNMT3B1 confer specificity for developmentally regulated CpG island methylation bit.ly/4aqP086
Neil Brockdorff reporting in Genes Dev
#Epigenetics #Chromatin #DNAm
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Epigenetics Update - Aging drives a program of DNA methylation decay in plant organs bit.ly/3NNXiiL
Ben P. Williams (University of California, Berkeley) reporting in Science
#Epigenetics #Aging #Plants #DNAm
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Epigenetics Update - Aberrant methylation limits antitumoral inflammation in lung adenocarcinoma by restricting RIPK3 expression bit.ly/4qr8gZU
Philipp J. Jost and Adam Wahida reporting in Sci Adv
#Epigenetics #LungCancer #DNAm
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Epigenetics Update - A robust computational framework for methylation age and disease-risk prediction based on pairwise learning go.nature.com/49wDPu4
#Epigenetics #DNAm #Aging #PairwiseLearning
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Epigenetics Update - DNA methylation shapes transcription factor binding beyond canonical CpG contexts bit.ly/4s54ruK
Ariel Afek (Weizmann Institute of Science) reporting in PNAS
#Epigenetics #DNAm
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Epigenetics Update – Investigation of a global mouse methylome atlas reveals subtype-specific copy number alterations in pediatric cancer models go.nature.com/4rWwxIG
Marc Zuckermann/Ulrich Schüller in Nat Genet
#Epigenetic #DNAm #Cancer
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Epigenetics Update - CDCA7 facilitates MET1-mediated CG DNA methylation maintenance in centromeric heterochromatin via linker histone H1 bit.ly/4pAjdbg
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Epigenetics Update - Iron homeostasis and cell clonality drive cancer-associated intestinal DNA methylation drift in aging go.nature.com/4ijta9Y
Francesco Neri reporting in Nat Aging
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Epigenetics Update - A chromatin-linked CPL2–PHD2/3 module sustains multiple DNA methylation pathways and Polycomb silencing bit.ly/3LYXKd5
Jian-Kang Zhu reporting in PNAS
#Epigenetics #Chromatin #DNAm #Polycomb #Plants
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Epigenetics Update – Transcription factors instruct DNA methylation patterns in plant reproductive tissues go.nature.com/4rbGrFR
Julie A. Law reporting in Nat Cell Biol
#Epigenetics #DNAm #Plants #Chromatin
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Epigenetics Update - Genetic elements promote retention of extrachromosomal DNA in cancer cells go.nature.com/4rqIyWz
Paul S. Mischel and Howard Y. Chang (Stanford University) reporting in Nature
#Epigenetics #ecDNA #DNAm
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Epigenetics Update - Adenine DNA methylation associated with transcriptionally permissive chromatin is widespread across eukaryotes go.nature.com/4r4V8KN
Alex de Mendoza (QMU, London) in Nat Genet
#Epigenetics #DNAm #Chromatin
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Epigenetics Update – Reprogramming of H3K36me2 guides lineage-specific post-implantation de novo DNA methylation go.nature.com/43jkfzm
#Epigenetics #DNAm #H3K36me2 #Development
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Epigenetics Update - Blood methylome signatures in children exposed to maternal type 1 diabetes are linked to protection against islet autoimmunity go.nature.com/4nFnd8s
#Epigenetics #DNAm #T1D #Diabetes
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Epigenetics Update - Roles of transposable elements and DNA methylation in the formation of CpG islands and CpG-depleted regulatory elements bit.ly/4ocNpsi
#Epigenetics #DNAm #DNAme #CpGIslands
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Epigenetics Update - Mechanisms of DNMT3A–3L-mediated de novo DNA methylation on chromatin go.nature.com/3X4LVUP
Peter A. Jones and Ting-Hai Xu reporting in NSMB
#Epigenetics #DNAm #Chromatin
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Epigenetics Update - Single-cell multi-omic detection of DNA methylation and histone modifications reconstructs the dynamics of epigenomic maintenance go.nature.com/46qdNsh
#Epigenetics #Chromatin #SingleCell #Multiomics #DNAm
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Epigenetics Update - Cell-type-specific DNA methylation dynamics in the prenatal and postnatal human cortex bit.ly/4gH3vYd
Alice Franklin/Jonathan Mill (University of Exeter) reporting in Cell Genomics
#Epigenetics #DNAme #DNAm
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Epigenetics Update - Systems Age: a single blood methylation test to quantify aging heterogeneity across 11 physiological systems go.nature.com/42qOLqf
#Epigenetics #Aging #DNAme #DNAm #EpigeneticAging
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Epigenetics Review - Non-CG DNA methylation in animal genomes go.nature.com/41NGOLH
Alex de Mendoza and Ozren Bogdanovic reporting in Nat Genet
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Epigenetics Update - DNA methylation cooperates with genomic alterations during non-small cell lung cancer evolution go.nature.com/4m7ipYV
Peter Van Loo and Nnennaya Kanu reporting in Nat Genet
#Epigenetics #DNAme #DNAm #Cancer
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Epigenetics Update - Fluctuating DNA methylation tracks cancer evolution at clinical scale go.nature.com/3Ve4OUy
#Epigenetics #Cancer #DNAme #DNAm
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Epigenetics Update - DNA methylation influences human centromere positioning and function go.nature.com/4mGYiSi
Nicolas Altemose (Stanford) and Daniele Fachinetti (Sorbonne Université) reporting in Nat Genet
#Epigenetics #DNAme #DNAm #DNAmethylation
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