📚 New Review for your weekend reading!
Liquid biopsy epigenetics: establishing a molecular profile based on cell-free DNA
🔓 buff.ly/4a4AmPZ
#Epigenetics #LiquidBiopsy #CellFreeDNA #cfDNA
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#cfDNA
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Epigenetics Update - Cell-free DNA fragmentomes for noninvasive detection of liver cirrhosis and other diseases bit.ly/4aQzmEw
Jillian Phallen, Robert B. Scharpf, and Victor E. Velculescu (Johns Hopkins) reporting in Sci TM
#Epigenetics #cfDNA
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Discover the breakthrough at epigenometech.com
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Wisdom Bioscience establishes SAB with leading experts in #cfDNA, #oncology screening & #moleculardiagnostics: Drs Giulia Kennedy, Arnold Levine , John Sninsky, Martin Goldberg & Prof Tin Tin Su. #pressrelease🗞️https://wisdombioscience.com/ #oralcancer #dental #NGS #messengersinscience
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Can we reuse NIPT cfDNA datasets to decode cfDNA biology? Nature Communications presents the first large-scale cfGWAS (28,016 pregnancies), revealing genetic regulators of cfDNA end motifs - promising for better liquid biopsy design. doi.org/10.1038/s414...
#cfDNA #cfGWAS #LiquidBiopsy #Genomics
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Epigenetics Update – A pan-cancer compendium of 1,294 plasma cell-free DNA methylomes and fragmentomes enabling multicancer detection go.nature.com/4qGhUaj
#Epigenetics #cfDNA #Cancer #DNAm
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High-resolution insights without cell sorting; epigenometech.com
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🥳 Our 8th most downloaded #REVIEW in 2025:
Genomic and fragmentomic landscapes of cell-free DNA for early cancer detection
#cfDNA #liquidbiopsy @NatResCancer
#NRCtop10of2025
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MobiCT: a UMI-based circulating tumor DNA analysis pipeline. #UMIs #cfDNA #Nextflow #Bioinformatics #Genomics #NARgenomicsAndBioinformatics 🧪🧬 🖥️
academic.oup.com/nargab/artic...
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New study: blood test using #cfDNA methylation detects multiorgan damage from immune checkpoint inhibitors — found in all patients with #irAE, sometimes weeks before symptoms. Suggests therapy causes systemic loss of immune tolerance. www.nejm.org/doi/full/10.... @funchainmd.bsky.social
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The December #ISHLTJournalWatch highlights pulmonology research, edited by @sirusjj.bsky.social.
Topics include gliptins and #CLAD, #cfDNA in #EVLP perfusate, lung allocation strategy, and #connectivetissue diseases in #lungtx.
#ISHLT #pulmsky #transplantsky
www.ishlt.org/about/news-d...
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Universal noninvasive prenatal diagnosis for monogenic disorders using cell-free plasma DNA. #cfDNA #MonogenicDisorders #PrenatalDiagnosis #GenomeMedicine
link.springer.com/article/10.1...
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The effects of bioinformatics preprocessing on cell-free DNA fragment analysis. #cfDNA #Bioinformatics #DataProcessing #FragmentAnalysis @gigascience.bsky.social 🧪🧬 🖥️
academic.oup.com/gigascience/...
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Heat, cold & time degrade liquid biopsy samples. The TAG FLEX-LB™ BCT stabilizes cfDNA, cfRNA, & total RNA for 7 days. One tube. Multiple biomarkers.
Protect Your Science. Perfect Your Signal. Meet us at #AMP2025 (Boston, Nov 11-15) to get your eval kit. #LiquidBiopsy #cfDNA
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We’re heading to Orlando for the International Society for Liquid Biopsy Annual Congress!
Booth #208 | 📅 Nov 1–3
Meet Giuseppe & Nuria to talk all things #LiquidBiopsy and #SamplePrep.
#cfDNA #cfRNA #Exosomes
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Proud to share a new study advancing non-invasive immune monitoring in cancer. Researchers found tumor-derived TCR clonotypes enriched in cfDNA and persisting >50 weeks in circulating T cells.
Proud that MiXCR powered large-scale TCR sequencing across tumor, blood, and cfDNA.
#cfDNA #TCRseq #TCR
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See you @ #ISLB2025 2025.islb.info TAG R&D Director Emily Medina, PhD presents a poster on Nov 1, 11:15am on TAG FLEX-LB performance results under real world thermal stress (37C/4C/ambient) and shares data on NGS apps, and stabilizing tricks for #cfRNA & #cfDNA. #LiquidBiopsy
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New in Pathology in Practice: Dr Stephanie Anderson (Promega UK) explores donor-derived cfDNA as a non-invasive biomarker for kidney transplant monitoring, offering earlier insight into graft health
Read the full article in the October issue: https://tinyurl.com/PiPOct2025
#Transplantation #cfDNA
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Expanding the scope of non-invasive prenatal screening. #NIPS #cfDNA #cfRNA #Genetics @natgenet.nature.com
www.nature.com/articles/s41...
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Quantitative analysis of BLV #cfDNA in cattle plasma achieves 100% sensitivity and specificity for diagnosing enzootic bovine leukosis - highlighting cfDNA as a highly effective #biomarker for veterinary #retrovirus #diagnostics🐄🧬🔍
📄 https://doi.org/10.1111/1348-0421.13231
👤 EVBC: Arif Ansori
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Cell-free DNA as a potential alternative to genomic DNA in genetic studies. #cfDNA #DNAseq #GeneticStudies #NARgenomicsAndBioinformatics
academic.oup.com/nargab/artic...
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The Role of cfDNA in Biliary Tract Cancer: Clinical and Prognostic Perspectives
oncodaily.com/oncolibrary/...
#OncoDaily #Oncology #Cancer #Health #Medicine #MedEd #MedOnc #MedNews #cfDNA #BiliaryTractCancer #BTC
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Synapse: Your Connection to our MSK Authors
Meet: Jennifer Ann Kennedy
Research Focus: Medicine; Senior Genetic Counselor
Detection and characterization of RB1 mosaicism in patients with retinoblastoma receiving cfDNA test
synapse.mskcc.org/synapse/work...
#Retinoblastoma #RB1 #cfDNA
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FinaleToolkit: Accelerating Cell-Free DNA Fragmentation Analysis with a High-Speed Computational Toolkit. #cfDNA #FragmentationAnalysis #genomics #bioinformatics @biorxiv-bioinfo.bsky.social
www.biorxiv.org/content/10.1...
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Excited to share our new paper: "Genome-wide cfDNA fragmentation patterns in cerebrospinal fluid reflect medulloblastoma groups."
nature.com/articles/s41...
#Medulloblastoma #Fragmentomics #LiquidBiopsy #cfDNA #CerebrospinalFluid
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NIPT is one of the fastest growing tools in modern prenatal care. But how does it work and why does it matter?
Our latest blog breaks it down in a clear, accessible way.
🔗 Read here: norgenbiotek.com/blog/non-inv...
#NIPT #Genomics #cfDNA #PrenatalScreening #Biotech #NorgenBiotek
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Exciting news! We’re thrilled to have @biomodalhq sponsoring and presenting at www.esconference25.com! Catch their session on how multiomic 6-base sequencing improves early colorectal cancer detection from cell-free DNA.
🔗 biomodal.com/events/2025-...
#epigenetics #cfDNA #colorectalcancer
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🧬 What causes a stroke when no cause is found?
The CANTO study explores cell-free DNA as a clue to cryptogenic strokes. Blood & clot analyses may reveal hidden mechanisms — a step toward better diagnosis, prevention & precision medicine.
#Stroke #cfDNA #ClinicalResearch
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We're actively developing a novel high-sensitive method for #cfDNA analysis and anticipate a preprint on that approach very soon. Exciting times ahead for #LiquidBiopsy in #GBM research! Kudo's to @tgenresearch.bsky.social for supporting this work and #PrecisionMedicine in general!
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We are excited to share our latest work highlighting the potential of liquid biopsies for pediatric CNS tumor patients - just published in Acta Neuropathologica Communications! Thank you to everyone who contributed to this study! doi.org/10.1186/s404... #LiquidBiopsy #cfDNA #PediatricNeuroOncology
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[NEW Blog] Looking for the best way to utilize #liquidbiopsy as a diagnostic tool? The new, minimally invasive PeCan-Seq deep sequencing method brings cost-effective analysis of #cfDNA to pediatric cancer. From @stjuderesearch.bsky.social
🎗️ bit.ly/44Ejt0J
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Join our 🧬 #LiquidBiopsy team at Queen Mary University of London’s Blizard Institute Genome Centre as a 🔬 Research Technician. Develop cutting-edge pipelines to extract genetic and epigenetic information from #cfDNA and RNA.
🗓️ Deadline: 24th July 2025
✅ Apply: tinyurl.com/bdercjp4
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