[eMicrobe]When cerebrospinal fluid cultures are negative, a study evaluates mNGS for CNS infections, showing positive clinical impact in 65.6% of patients.
www.sciltp.com/journals/eMi...
#metagenomicnextgenerationsequencing #cerebrospinalfluid #centralnervoussysteminfection #pathogen #clinicalimpact
28 THE CENTRAL NERVOUS SYSTEM, BRAIN AND SPINAL CORD EXPLAINED #50LAM_ANATOMY_ENG
youtube.com/shorts/TfCb7...
#centralnervoussystem #brain #spinalcord #cnsanatomy #neuroscience #nervoussystem #cerebrum #cerebellum #brainstem #cerebrospinalfluid
A Prediction Model for Detecting Dysthyroid Optic Neuropathy Based on Clinical Factors and Imaging Markers of the Optic Nerve and Cerebrospinal Fluid in the Optic Nerve Sheath
A noninvasive model combining #OpticNerve imaging and #CerebroSpinalFluid sheath metrics predicts #DysthyroidOpticNeuropathy in #ThyroidAssociatedOphthalmopathy with high accuracy, supporting early detection and risk stratification in clinical practice.
Read: doi.org/10.1007/s115...
🧠 Precise #tumour classification — without tumour tissue?
An international team incl. #MedUniVienna developed an #AI-based method to classify #braintumours via genetic material from #cerebrospinalfluid & monitor disease progression.
📖 @natcancer.nature.com
The paper reveals neurological disease outcomes of tick-borne #encephalitis #virus (#TBEV), and associated #metabolomics in the #CerebrospinalFluid (#CSF).
The group investigated the host #immune and metabolic responses with specific TBEV neurological infectious outcomes.
New Episode: youtu.be/ssy9vK03Tyo
#mindfulness #mindfulnessbasedcognitivetherapy #mindfulnessbasedprograms #mindfulnessbasedstressreduction #depression #anxiety #stress #cerebrospinalfluid #Alzheimers #dementia
This has significant implications for brain health, particularly around cognitive decline from aging or illness.
www.pnas.org/doi/10.1073/...
#mindfulness #mentalhealth #brainhealth #cerebrospinalfluid #focusedattention #attentionregulation #neurodegeneration #alzheimers #dementia
Study by Hugh Markus, et al. at Cambridge found impaired movement of #CerebrospinalFluid predicted #Dementia risk later in life among 40,000 adults recruited to the @ukbiobank.bsky.social. @alzdemjournals.bsky.social @alzassociation.bsky.social
➡️ alz-journals.onlinelibrary.wiley.com/doi/10.1002/...
Homeostasis in Action: How the Brain Stays Sharp and Healthy
#BrainScience #NeuroscienceExplained #BrainHealth #Neurobiology #CerebrospinalFluid #CSF #BrainBarrier #Hydrocephalus #Neurotrophins #BrainFacts #MindMatters #Homeostasis #BrainFunction #GlialLymphatic
youtube.com/shorts/P9vYt...
From Ventricles to Vitality: The Fluid That Keeps You Thinking
#BrainScience #NeuroscienceExplained #CerebrospinalFluid #CSF #BrainHealth #Neurobiology #Hydrocephalus #BrainFacts #MindMatters #AnatomyOfTheBrain #Neurotrophins #BrainHomeostasis #BrainFunction
youtube.com/shorts/IaekV...
Excited to share our new paper: "Genome-wide cfDNA fragmentation patterns in cerebrospinal fluid reflect medulloblastoma groups."
nature.com/articles/s41...
#Medulloblastoma #Fragmentomics #LiquidBiopsy #cfDNA #CerebrospinalFluid
Coupled neuronal activity, gGM, PFI, and CSF fMRI signals during burst-suppression anesthesia. Top left: Experimental design: fMRI recording under deep sevoflurane anesthesia in a Philips Achieva 3.0T scanner. Bottom left: Example scan positioning in a representative subject. Schematic depiction of the fMRI volume superimposed on a sagittal T1-weighted image with representative slice positions for the gGM and PFI masks and slice 1, which contains the CSF mask. Middle: Simultaneous recordings of the EEG with an MRI-compatible, 64-electrode cap with equidistantly arranged electrodes (Easycap) and of three fMRI masks, depicted in representative slices: gGM (white), PFI (blue), and CSF (red). Right: Simultaneously recorded signal time courses from one subject under burst-suppression anesthesia: EEG (green), gGM fMRI (black), PFI fMRI (blue), and CSF fMRI (red). Suppression and burst periods are indicated in light blue and light orange, respectively.
The directed motion of #CerebrospinalFluid #CSF in the #brain is key for the distribution & removal of solutes, but how is this flux modulated? @bzottlab.bsky.social &co show that changes in total cerebral #blood volume drive the flow of CSF in humans @plosbiology.org 🧪 plos.io/4lOrHKm
Coupled neuronal activity, gGM, PFI, and CSF fMRI signals during burst-suppression anesthesia. Top left: Experimental design: fMRI recording under deep sevoflurane anesthesia in a Philips Achieva 3.0T scanner. Bottom left: Example scan positioning in a representative subject. Schematic depiction of the fMRI volume superimposed on a sagittal T1-weighted image with representative slice positions for the gGM and PFI masks and slice 1, which contains the CSF mask. Middle: Simultaneous recordings of the EEG with an MRI-compatible, 64-electrode cap with equidistantly arranged electrodes (Easycap) and of three fMRI masks, depicted in representative slices: gGM (white), PFI (blue), and CSF (red). Right: Simultaneously recorded signal time courses from one subject under burst-suppression anesthesia: EEG (green), gGM fMRI (black), PFI fMRI (blue), and CSF fMRI (red). Suppression and burst periods are indicated in light blue and light orange, respectively.
The directed motion of #CerebrospinalFluid #CSF in the #brain is key for the distribution & removal of solutes, but how is this flux modulated? @bzottlab.bsky.social &co show that changes in total cerebral #blood volume drive the flow of CSF in humans @plosbiology.org 🧪 plos.io/4lOrHKm
Coupled neuronal activity, gGM, PFI, and CSF fMRI signals during burst-suppression anesthesia. Top left: Experimental design: fMRI recording under deep sevoflurane anesthesia in a Philips Achieva 3.0T scanner. Bottom left: Example scan positioning in a representative subject. Schematic depiction of the fMRI volume superimposed on a sagittal T1-weighted image with representative slice positions for the gGM and PFI masks and slice 1, which contains the CSF mask. Middle: Simultaneous recordings of the EEG with an MRI-compatible, 64-electrode cap with equidistantly arranged electrodes (Easycap) and of three fMRI masks, depicted in representative slices: gGM (white), PFI (blue), and CSF (red). Right: Simultaneously recorded signal time courses from one subject under burst-suppression anesthesia: EEG (green), gGM fMRI (black), PFI fMRI (blue), and CSF fMRI (red). Suppression and burst periods are indicated in light blue and light orange, respectively.
The directed motion of #CerebrospinalFluid #CSF in the #brain is key for the distribution & removal of solutes, but how is this flux modulated? @bzottlab.bsky.social &co show that changes in total cerebral #blood volume drive the flow of CSF in humans @plosbiology.org 🧪 plos.io/4lOrHKm
Everything went well. Procedure was uncomfortable and a little painful.
Here is a bit of my brain fluid in a sample tube.
#BrainFluid #CerebrospinalFluid #lumbarpuncture
Effect of Sleeping pills
www.linkedin.com/pulse/effect...
#sleepingpills #ambien #zolpidem #benzodiazepine #norepinephrine #MaikenNedergaard #detoxifying #cerebrospinalfluid #CSF #NREM #qlymphaticsystem #bloodvessels #memory
#ChoroidPlexus #CerebrospinalFluid #CSF #LongCovid #hEDS
Is this what links The Trifecta? #EDS #POTS #MCAS
A look from above, nuclei in 🟢
Shown from a different angle without arteriole. The thin lines on the fibroblasts are primary cilia.
Closeup of macrophage between fibroblast processes.
As my first post on #Bluesky I am showing my #3Drendering of a pial #macrophage 🔵 squeezing between #fibroblast 🟡 processes next to a #penetratingarteriole. Nuclei in 🟢. Macrophages move around and help clean up waste in the #cerebrospinalfluid. www.biorxiv.org/content/10.1...
Yoda1, a #Piezo1 activator, rescues Mengineal #LymphaticVessel-mediated #CerebroSpinalFLuid drainage in🐭with #Aging (2 yr) or #Craniosynostosis (Twist1 deficiency)
45kD Ovalbumin tracer
How many regulatory layers of🧠CSF drainage can be controlled by Piezo1?
#JCI 2024
www.jci.org/articles/vie...
