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The Treatment of Antibody-Mediated Encephalitis: Current, Future Therapies, Unmet Need and Patient Management With growing insight into the underlying pathogenic mechanisms, treatment now targets multiple immune pathways, including emerging third-line therapies. What are the options for immunotherapy and…

With growing insight into the underlying pathogenic mechanisms, autoimmune #encephalitis treatment now targets multiple immune pathways, including emerging third-line therapies.

What are the options for immunotherapy and symptomatic management?

👉 buff.ly/80GB0SN

#NeuroSky

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PET reveals disease activity in autoimmune encephalitis PET revealed brain region-specific astrogliosis corresponding to clinical manifestations and disease severity.

Autoimmune encephalitis is a serious condition where the immune system attacks the brain, causing inflammation, cognitive decline, and psychiatric symptoms #radiology #encephalitis #PETimaging

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💙We need your help
🧠 Have you/your child had Encephalitis?
We’re carrying out important research & need your lived experience - your voice can make a difference!📢

⏰ It only takes a few mins - get involved today & help shape real change
📩 Email: contact@edendoratrust.org
Thank you
#Encephalitis #ABI

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Proud to support @cbituk.bsky.social by funding all the ‘UCABI’ workshops, with all attendees taking part at no additional cost to themselves 🧠
Ensuring everyone can become more informed about ABI & a YP’s needs after an ABI, enabling correct support for all 🙏

#ABI #Encephalitis #childhoodABI

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Role for NF-κB in #herpes #encephalitis pathology in mice genocopying an inborn error of IRF3-IFN immunity. From from Manja Idorn, Søren R. Paludan and colleagues: rupress.org/jem/article/...

📘 In our #InnateImmunity collection: rupress.org/jem/collecti...

#KSInnateImmune26

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Herpes Simplex Virus Encephalitis - Lucy's Story | Encephalitis International One moment I was living a normal life and the next everything changed. Lucy shares her story of herpes simplex virus encephalitis.

Almost identical to my own experience with HSV #Encephalitis in 2014

Diagnosed with Temporal Lobe Epilepsy in 2017.

www.encephalitis.info/story/herpes...

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Great to see the launch of this new #Encephalitis learning collection on BMJ Learning, designed to support doctors, trainees and the wider healthcare workforce with practical, evidence-based education.

Well done to everyone involved!

www.encephalitis.info/global-training-modules-on-encephalitis/

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#Facts Republicans #WhiteEvangelicals #VaccinesSavesLives #COVID Unvaccinated #children are at high risk from preventable infectious diseases like #measles and #influenza, which can lead to fatal #encephalitis or severe respiratory illness #Leukemia brain cancers top killers.Hib (Haemophilus

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Unusual Clinical Features of Toscana Virus Central Nervous System Infections in Italy Analysis of 35 neuroinvasive Toscana virus cases shows mostly mild meningitis with recovery, rare encephalitis needing ICU care, and rising neurotropic severity

This #Zoonoses study demonstrates that #ToscanaVirus is often asymptomatic or mild, yet its #Neurotropic nature can drive severe #NeurologicalDiseases, like #Meningitis & #Encephalitis, warranting further research to understand its broader impact on human health.

#OpenAccess: tinyurl.com/2a3gab5s

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What's Wrong With Them (Living with Autoimmune Encephalitis)
What's Wrong With Them (Living with Autoimmune Encephalitis) YouTube video by Miko

Please watch this documentary about anti-NMDAR autoimmune encephalitis. It might save the life of someone you love.
#encephalitis #autoimmuneencephalitis

m.youtube.com/watch?v=rLH-...

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Extreme flu? Weird encephalitis? It may be your genes Subtle mutations can undermine our ability to fend off a specific bug

#Medsky🧪#immunosky #pedsky #publichealth @casanovalab.bsky.social via @sciam.bsky.social The infection enigma . Extreme #flu? Weird #encephalitis? It may be your genes
Subtle mutations can undermine our ability to fend off a specific bug

www.scientificamerican.com/article/extr...

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Autoimmune Brain Disease: New Treatment Target Found - TIme News PORTLAND, Ore. – January 14, 2026 – Scientists have pinpointed a crucial target for treating a…

OHSU researchers identified specific binding sites on the NMDA receptor that, if blocked, could halt disease progression in people with anti-NMDA receptor autoimmune #encephalitis. time.news/autoimmune-brain-disease...

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Eden Dora Trust | for Children with Encephalitis

In honour of #WorldEncephalitisDay, we want to highlight the need for greater understanding, support, and research into #Encephalitis.

N-ABLES works closely with the @edendoratrust.bsky.social, who support young people affected by Encephalitis.

More information:

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What a read!

Inspiring to see the global reach and impact of World Encephalitis Day and the community driving awareness forward. Congratulations @encephalitisint.bsky.social

encephalitis.info/22-highlight...

#encephalitis #worldencephalitisday

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Rare 'Brain on Fire' disorder highlighted in Netflix film may soon have new treatments No standard treatments for the sometimes deadly disorder have been developed, but that may change due to the newly published research.

Nearly two decades after first being identified, a rare and life-threatening #brain-inflammation disease known as anti-NMDA #encephalitis may soon have new treatment candidates.

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Research Discovery: Autoimmune encephalitis is more common than previously thought, and it is often dismissed as stress or fatigue. It describes inflammation that disrupts normal brain function, sometimes caused by an infection, but not always.

Research Discovery: Autoimmune encephalitis is more common than previously thought, and it is often dismissed as stress or fatigue. It describes inflammation that disrupts normal brain function, sometimes caused by an infection, but not always.

Diseases Affected: Autoimmune encephalitis.

Diseases Affected: Autoimmune encephalitis.

Key Findings: While the disease is rare (affecting approximately 14 out of 100,000 people annually), testing and increased awareness suggest that this may be an underestimate, because the symptoms overlap with other common conditions and may not be visible.

Key Findings: While the disease is rare (affecting approximately 14 out of 100,000 people annually), testing and increased awareness suggest that this may be an underestimate, because the symptoms overlap with other common conditions and may not be visible.

What’s Next? There isn’t one single test to confirm autoimmune encephalitis, but researchers are developing better methods of assessment and symptom tracking that could aid in diagnosis.

What’s Next? There isn’t one single test to confirm autoimmune encephalitis, but researchers are developing better methods of assessment and symptom tracking that could aid in diagnosis.

Yesterday, February 22, was #WorldEncephalitisDay, founded by our partners @encephalitisint.bsky.social. The Conversation shares that autoimmune #encephalitis is rare but may be more common than once thought, because it can be easily misdiagnosed. #EncephalitisAwareness

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Thank you so much @cbituk.bsky.social for your birthday wishes 🫶
We love our relationship with you. Making a difference together is key 💙

#ABI #Encephalitis #ChildhoodEncephalitis #WorldEncephalitisDay #edtbirthday #12years #collaboration #TeamWork

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World Encephalitis Day | Encephalitis International Get involved with World Encephalitis Day on 22 February - the global awareness day for encephalitis (inflammation of the brain).

Today is World Encephalitis Day

#science #medicine #health #encephalitis
www.encephalitis.info/world-enceph...

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& the viruses can still cause primary infection of the brain or post infectious autoimmune responses.
These are 3 viruses that can cause #encephalitis.
The #MMRVvaccine protects children against all-3 of these viruses,

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Human TBK1 deficiency: An expanded spectrum from #autoinflammation to viral #encephalitis. New report from Yemsratch Akalu, Dusan Bogunovic @bogunoviclab.bsky.social @columbiamed.bsky.social and colleagues: rupress.org/jhi/article/...

#InbornErrorsOfImmunity
@clinimmsoc.bsky.social

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Rare 'Brain on Fire' disorder highlighted in Netflix film may soon have new treatments No standard treatments for the sometimes deadly disorder have been developed, but that may change due to the newly published research.

A treatment for anti-NMDA #encephalitis may soon emerge after OHSU researchers discovered neurotransmitter receptors in the #brain that, if blocked, could reverse the disease's progression.

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Figure. 2. Clinical manifestations of West Nile virus infections.

Figure. 2. Clinical manifestations of West Nile virus infections.

- Most patients were male (55%) with mean age of 52 years .
Overall mortality rate was 6.23%, rising to 62% among #ICU patients
-CNS symptoms were most frequent (39.39%), followed by systemic symptoms (31.21%)
Fever, headache & #encephalitis were the most commonly reported symptoms .

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Human TBK1 deficiency: An expanded spectrum from autoinflammation to viral encephalitis Akalu et al. report new and long-term follow-up cases of human TBK1 deficiency, revealing that, beyond systemic autoinflammation, affected individuals are

In @jhumimmunity.org, Akalu et al. @bogunoviclab.bsky.social report new and long-term follow-up cases of human #TBK1 deficiency, revealing that, beyond systemic #autoinflammation, affected individuals are also vulnerable to severe viral #encephalitis. rupress.org/jhi/article/...

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Akalu et al. @bogunoviclab.bsky.social @columbiamed.bsky.social report new and long-term follow-up cases of human #TBK1 deficiency, revealing that, beyond systemic #autoinflammation, affected individuals are also vulnerable to severe viral #encephalitis. rupress.org/jhi/article/...

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Brain swelling is one of measles’ nastiest side effects, and it’s happening in South Carolina The South Carolina measles outbreak has triggered rare but serious brain swelling in some children

“A straightforward case of measles is nasty—but the disease’s complications are even worse. One of those complications has been confirmed in the ongoing, record-breaking #measles outbreak in South Carolina: #encephalitis, or #BrainSwelling.”

www.scientificamerican.com/article/sout...

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Measles Is Causing Brain Swelling in Children in South Carolina In the ongoing measles outbreak in South Carolina that has infected more than 800 people, some children have developed a rare but serious complication called encephalitis.

www.wired.com/story/measle...

#measles. #encephalitis

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Measles Is Causing Brain Swelling in Children in South Carolina In the ongoing measles outbreak in South Carolina that has infected more than 800 people, some children have developed a rare but serious complication called encephalitis.

Some children affected by measles in the ongoing South Carolina outbreak have developed a serious complication of the disease called #encephalitis, or swelling of the brain, state epidemiologist Linda Bell said on Wednesday.

The SC measles outbreak began in October with a handful of infections.

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Virologist warns of Nipah virus risk from bats Thailand is at risk from the Nipah virus because it is carried by fruit bats, which are found nationwide, according to prominent virologist Yong Poovorawan.

#Virologist warns of #Nipah #virus risk from #bats ...

| #pathogen | #Thailand | #encephalitis | #publichealth | Via bangkokpost .com

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Here you can see a cryoEM structure of the Eastern Equine Encephalitis Virus (PDB code: 6MX4)

Rendering by Francisco J. Enguita made with #ProteinImager

3dproteinimaging.com/protein-imag...

#SciArt #molecularart #virus #cryoem #equine #encephalitis

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Multipanel figure showing pathological changes in the brains and the peripheral organs of the investigated mouse models. Panel A: Images of the brains obtained from C57BL/6J mice not infected with JEV (Control), C57BL/6J, NCG and NCG-hSTAT2+/+ mice showing retention of Evans Blue. Panel B: Images, showing histopathological changes of the hippocampal area in the brains of mice as described in panel A. Panel C: a graph shoeing quantification of neuronal cell density in the hippocampus of the mice as described in panel B. Panel D: Images showing immunofluorescence staining of neuronal cells in the dentate gyrus region. Panel E: Histological images of liver and spleen tissues in mice, showing pathological changes in these peripheral organs.

Multipanel figure showing pathological changes in the brains and the peripheral organs of the investigated mouse models. Panel A: Images of the brains obtained from C57BL/6J mice not infected with JEV (Control), C57BL/6J, NCG and NCG-hSTAT2+/+ mice showing retention of Evans Blue. Panel B: Images, showing histopathological changes of the hippocampal area in the brains of mice as described in panel A. Panel C: a graph shoeing quantification of neuronal cell density in the hippocampus of the mice as described in panel B. Panel D: Images showing immunofluorescence staining of neuronal cells in the dentate gyrus region. Panel E: Histological images of liver and spleen tissues in mice, showing pathological changes in these peripheral organs.

Caiqin Zhang, Yangchao Don, Changhong Shi, & co developed a humanised STAT2 #MouseModel of Japanese #encephalitis #virus, which exhibited a phenotype resembling clinical human infections, characterised by elevated viral load and increased proinflammatory cytokines.

Read doi.org/10.1242/dmm....

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