With growing insight into the underlying pathogenic mechanisms, autoimmune #encephalitis treatment now targets multiple immune pathways, including emerging third-line therapies.
What are the options for immunotherapy and symptomatic management?
👉 buff.ly/80GB0SN
#NeuroSky
Autoimmune encephalitis is a serious condition where the immune system attacks the brain, causing inflammation, cognitive decline, and psychiatric symptoms #radiology #encephalitis #PETimaging
💙We need your help
🧠 Have you/your child had Encephalitis?
We’re carrying out important research & need your lived experience - your voice can make a difference!📢
⏰ It only takes a few mins - get involved today & help shape real change
📩 Email: contact@edendoratrust.org
Thank you
#Encephalitis #ABI
Proud to support @cbituk.bsky.social by funding all the ‘UCABI’ workshops, with all attendees taking part at no additional cost to themselves 🧠
Ensuring everyone can become more informed about ABI & a YP’s needs after an ABI, enabling correct support for all 🙏
#ABI #Encephalitis #childhoodABI
Role for NF-κB in #herpes #encephalitis pathology in mice genocopying an inborn error of IRF3-IFN immunity. From from Manja Idorn, Søren R. Paludan and colleagues: rupress.org/jem/article/...
📘 In our #InnateImmunity collection: rupress.org/jem/collecti...
#KSInnateImmune26
Almost identical to my own experience with HSV #Encephalitis in 2014
Diagnosed with Temporal Lobe Epilepsy in 2017.
www.encephalitis.info/story/herpes...
Great to see the launch of this new #Encephalitis learning collection on BMJ Learning, designed to support doctors, trainees and the wider healthcare workforce with practical, evidence-based education.
Well done to everyone involved!
www.encephalitis.info/global-training-modules-on-encephalitis/
#Facts Republicans #WhiteEvangelicals #VaccinesSavesLives #COVID Unvaccinated #children are at high risk from preventable infectious diseases like #measles and #influenza, which can lead to fatal #encephalitis or severe respiratory illness #Leukemia brain cancers top killers.Hib (Haemophilus
This #Zoonoses study demonstrates that #ToscanaVirus is often asymptomatic or mild, yet its #Neurotropic nature can drive severe #NeurologicalDiseases, like #Meningitis & #Encephalitis, warranting further research to understand its broader impact on human health.
#OpenAccess: tinyurl.com/2a3gab5s
Please watch this documentary about anti-NMDAR autoimmune encephalitis. It might save the life of someone you love.
#encephalitis #autoimmuneencephalitis
m.youtube.com/watch?v=rLH-...
#Medsky🧪#immunosky #pedsky #publichealth @casanovalab.bsky.social via @sciam.bsky.social The infection enigma . Extreme #flu? Weird #encephalitis? It may be your genes
Subtle mutations can undermine our ability to fend off a specific bug
www.scientificamerican.com/article/extr...
OHSU researchers identified specific binding sites on the NMDA receptor that, if blocked, could halt disease progression in people with anti-NMDA receptor autoimmune #encephalitis. time.news/autoimmune-brain-disease...
In honour of #WorldEncephalitisDay, we want to highlight the need for greater understanding, support, and research into #Encephalitis.
N-ABLES works closely with the @edendoratrust.bsky.social, who support young people affected by Encephalitis.
More information:
What a read!
Inspiring to see the global reach and impact of World Encephalitis Day and the community driving awareness forward. Congratulations @encephalitisint.bsky.social
encephalitis.info/22-highlight...
#encephalitis #worldencephalitisday
Nearly two decades after first being identified, a rare and life-threatening #brain-inflammation disease known as anti-NMDA #encephalitis may soon have new treatment candidates.
Research Discovery: Autoimmune encephalitis is more common than previously thought, and it is often dismissed as stress or fatigue. It describes inflammation that disrupts normal brain function, sometimes caused by an infection, but not always.
Diseases Affected: Autoimmune encephalitis.
Key Findings: While the disease is rare (affecting approximately 14 out of 100,000 people annually), testing and increased awareness suggest that this may be an underestimate, because the symptoms overlap with other common conditions and may not be visible.
What’s Next? There isn’t one single test to confirm autoimmune encephalitis, but researchers are developing better methods of assessment and symptom tracking that could aid in diagnosis.
Yesterday, February 22, was #WorldEncephalitisDay, founded by our partners @encephalitisint.bsky.social. The Conversation shares that autoimmune #encephalitis is rare but may be more common than once thought, because it can be easily misdiagnosed. #EncephalitisAwareness
Thank you so much @cbituk.bsky.social for your birthday wishes 🫶
We love our relationship with you. Making a difference together is key 💙
#ABI #Encephalitis #ChildhoodEncephalitis #WorldEncephalitisDay #edtbirthday #12years #collaboration #TeamWork
Today is World Encephalitis Day
#science #medicine #health #encephalitis
www.encephalitis.info/world-enceph...
& the viruses can still cause primary infection of the brain or post infectious autoimmune responses.
These are 3 viruses that can cause #encephalitis.
The #MMRVvaccine protects children against all-3 of these viruses,
Human TBK1 deficiency: An expanded spectrum from #autoinflammation to viral #encephalitis. New report from Yemsratch Akalu, Dusan Bogunovic @bogunoviclab.bsky.social @columbiamed.bsky.social and colleagues: rupress.org/jhi/article/...
#InbornErrorsOfImmunity
@clinimmsoc.bsky.social
A treatment for anti-NMDA #encephalitis may soon emerge after OHSU researchers discovered neurotransmitter receptors in the #brain that, if blocked, could reverse the disease's progression.
Figure. 2. Clinical manifestations of West Nile virus infections.
- Most patients were male (55%) with mean age of 52 years .
Overall mortality rate was 6.23%, rising to 62% among #ICU patients
-CNS symptoms were most frequent (39.39%), followed by systemic symptoms (31.21%)
Fever, headache & #encephalitis were the most commonly reported symptoms .
In @jhumimmunity.org, Akalu et al. @bogunoviclab.bsky.social report new and long-term follow-up cases of human #TBK1 deficiency, revealing that, beyond systemic #autoinflammation, affected individuals are also vulnerable to severe viral #encephalitis. rupress.org/jhi/article/...
Akalu et al. @bogunoviclab.bsky.social @columbiamed.bsky.social report new and long-term follow-up cases of human #TBK1 deficiency, revealing that, beyond systemic #autoinflammation, affected individuals are also vulnerable to severe viral #encephalitis. rupress.org/jhi/article/...
“A straightforward case of measles is nasty—but the disease’s complications are even worse. One of those complications has been confirmed in the ongoing, record-breaking #measles outbreak in South Carolina: #encephalitis, or #BrainSwelling.”
www.scientificamerican.com/article/sout...
www.wired.com/story/measle...
#measles. #encephalitis
Some children affected by measles in the ongoing South Carolina outbreak have developed a serious complication of the disease called #encephalitis, or swelling of the brain, state epidemiologist Linda Bell said on Wednesday.
The SC measles outbreak began in October with a handful of infections.
#Virologist warns of #Nipah #virus risk from #bats ...
| #pathogen | #Thailand | #encephalitis | #publichealth | Via bangkokpost .com
Here you can see a cryoEM structure of the Eastern Equine Encephalitis Virus (PDB code: 6MX4)
Rendering by Francisco J. Enguita made with #ProteinImager
3dproteinimaging.com/protein-imag...
#SciArt #molecularart #virus #cryoem #equine #encephalitis
Multipanel figure showing pathological changes in the brains and the peripheral organs of the investigated mouse models. Panel A: Images of the brains obtained from C57BL/6J mice not infected with JEV (Control), C57BL/6J, NCG and NCG-hSTAT2+/+ mice showing retention of Evans Blue. Panel B: Images, showing histopathological changes of the hippocampal area in the brains of mice as described in panel A. Panel C: a graph shoeing quantification of neuronal cell density in the hippocampus of the mice as described in panel B. Panel D: Images showing immunofluorescence staining of neuronal cells in the dentate gyrus region. Panel E: Histological images of liver and spleen tissues in mice, showing pathological changes in these peripheral organs.
Caiqin Zhang, Yangchao Don, Changhong Shi, & co developed a humanised STAT2 #MouseModel of Japanese #encephalitis #virus, which exhibited a phenotype resembling clinical human infections, characterised by elevated viral load and increased proinflammatory cytokines.
Read doi.org/10.1242/dmm....