FKBP5 Regulates the Osteogenesis of Human Adipose-derived Mesenchymal Stem Cells
This research shows that #FKBP5 promotes ASC #OsteogenicDifferentiation, highlighting the potential of FKBP5 targeted therapies for #BoneDisorders & proposing a controllable strategy for ASC based #Transplantation in #BoneDefect repair. #medsky
Read: doi.org/10.1007/s115...
AJT Highlights April 2026 Editor's Picks
🎙️ New AJT Highlights episode now available!
🎧 Listen here: ajthighlights.podbean.com
#Transplantation #OrganTransplantation #Transplant
#TBT to this week's featured top downloaded paper from 2024: CHALF Score: A Novel Tool to Rapidly Risk Stratify Children in Need of Liver Transplant Evaluation During Acute Liver Failure #Transplantation #Med tinyurl.com/2s3trazs
👉 Check out From Insight to Action: Integrating Cell-Free DNA Testing into Daily Transplant Care by #Natera, which is now available on-demand. Leading voices in #transplantation have a dynamic discussion on #cfDNA technology.💡📽️ Watch now at 🔗 bit.ly/4bYH7aU
A UK-based study have reported the successful transplantation of a lab-grown oesophagus into pigs for the first time and led to the restoration of normal swallowing in the animals.
Read more for FREE in BioNews ⬇️
progress.org.uk/lab-grown-oe...
#Transplantation #Oesophagus #Science
Over 20 years of data show that DCD islets perform as well as DBD islets—with a trend toward better diabetes reversal. A promising way to increase donor availability for type 1 diabetes treatment. #TXPforall #Transplantation tinyurl.com/4p255ryk
Figure 1 Proportion of the follow-up time among solid organ transplant recipients in the United States during 1995-2021, by calendar year, according to attained age in years (A) or years since first transplant (B).
🔓 Open Access
"Population-level cancer trends among solid organ transplant recipients in the United States during 1995-2021," by Engels et al is now online & in press!
doi.org/10.1016/j.aj...
#Transplantation #Oncology #CancerEpidemiology #PopulationHealth #PublicHealth #TransplantOncology
This study shows persistent socioeconomic disparities in England—affecting access, donor type, and outcomes—while Northern Ireland shows more equitable access. Healthcare delivery models clearly matter! #TXPforall #Transplantation tinyurl.com/mr7aj24c
The 4th #ECTORSmeeting offers two highly focused days of cutting-edge science, translational insight and in-depth discussion, with strong interaction across career stages.
#ECTORSmeeting #Transplantation #RegenerativeMedicine #CellTherapy
Supplementary figure
Online & In press: "Racial and immunologic disparities impact access to kidney rewaitlisting and retransplantation," by Lovasik et al
www.amjtransplant.org/article/S160...
#OpenAccess #KidneyTransplant #Transplantation #HealthEquity
Can alkaline phosphatase (ALP) protect donor kidneys? In a porcine model, adding ALP during preservation improved energy status and reduced metabolic stress after reperfusion. Promising strategy to reduce delayed graft function #TXPforAll #Transplantation tinyurl.com/muyxpww6
Banff Foundation for Allograft Pathology logo
🔓 Open Access
"The Banff 2024 Kidney Meeting Report: Rejection as a spectrum of phenotypes and focus on differential diagnostic reasoning," Naesens et al.
www.amjtransplant.org/article/S160...
#Transplantation #KidneyTransplant #Banff #TransplantPathology #DifferentialDiagnosis #OpenAccess
#TBT to this week's featured top downloaded paper from 2025: The Fourth International Consensus Guidelines on the Management of Cytomegalovirus in Solid Organ Transplantation #Transplantation #Med tinyurl.com/y3wffwxj
#ZdK begrüßt geplante Änderung des Transplantationsgesetzes
Stetter-Karp: „Aktive Entscheidung pro #Organspende wird immer wichtiger“
Zur #Pressemitteilung: www.zdk.de/presse/2026/...
#Transplantation #Kirche #Katholisch #ZdK
Selon les nouvelles directives du Vatican, les catholiques peuvent recevoir des greffes d’organes provenant d’animaux #Vatican #ÉgliseCatholique #GreffesDOrganes #Transplantation #Bioéthique
Preclinical and clinical studies indicate that NKX6.1 mRNA expression could serve as a biomarker to predict islet graft function independently of islet mass, purity, and viability #transplantation #T1D www.science.org/doi/10.1126/...
Figure 1 Most likely scenario simulation. The figure presents the total number of new donors (A), the family voucher coverage (B), and the overall voucher program coverage (C) over the 100-year time horizon.
Featured in our March issue, "A 100-year simulation of the National Kidney Registry’s voucher program," by Cooper et al.
doi.org/10.1016/j.aj...
#KidneyTransplant #Transplantation #OrganDonation #Nephrology #NationalKidneyRegistry #TransplantResearch
COMMENT: ‘Hello Hugo! First UK birth following a uterus transplant from a deceased donor’.
Read more for free in BioNews⬇️
progress.org.uk/hello-hugo-f...
#UterusTransplant #Birth #Gestation #Uterus #FamilyFormation #Transplantation #UK #WombTransplantUK #Ethics #ClinicalTrials
Figure 1 Dynamics of donor-specific immunoglobulin (Ig) E and basophils over time.
Check out, "Donor major histocompatibility complex–specific immunoglobulin E augments the T and B cell alloresponse in a CD23-dependent manner," by Weijler et al in our March issue.
doi.org/10.1016/j.aj...
#Transplantation #Immunology #TransplantImmunology #IgE #CardiacTransplantation
❤️ This study by Rosethal et al. shows that clinical follow-up + echocardiography (TDI) may safely monitor rejection, with high graft survival and low detection yield from routine biopsies. Less invasive care looks promising! #TXPforAll #Transplantation tinyurl.com/cnwc64wr
Figure 1 Functional MerTK promotes cardiac allograft survival and limits vascular injury.
Check out, "Suppression of cardiac allograft vasculopathy by a macrophage efferocytosis receptor," by Shah et al, in our March issue!
www.amjtransplant.org/article/S160...
#HeartTransplant #Transplantation #Cardiology
This review by Cantarelli et al. highlights how EPO promotes tolerance, dampens inflammation, and shapes T cells and macrophages in kidney disease and #transplantation. #TXPforAll #Immunology tinyurl.com/5x79n7b5
✈️ Looking forward to my trip to Thailand 🇹🇭 with lectures on various #transplantation topics over the next few days including:
1️⃣ Post-transplantation diabetes
2️⃣ Post-transplant cancer (and the EpCOT study)
3️⃣ UK experience with marginal donors and pre-implant biopsies
🇬🇧 🇹🇭
Injectable “satellite livers” could offer an alternative to liver #transplantation.
#science #news
www.lifescience.net/news/7044/in...
🩸 Happening next week!
Register: hemehub.org/live-webinars
Submit your cases: hemehub.org/case-submiss...
#Myelofibrosis #MPN #Hematology #BloodCancer #JAKInhibitors #BoneMarrow #Transplantation #HemeHub #BloodDisorders @mayocliniccancer.bsky.social @mayoclinic.org
Presenters at the meeting
Dr. Suzanne Watnick
👏👏👏Thank you to Dr. Suzanne Watnick for her amazingly powerful testimony at a Health Subcommittee Hearing in DC, providing insights and answers on the state of #dialysis care & #transplantation for Americans living with #kidney diseases. Watch: asn.click/4sVAVY2
#nephsky @uwmedicine.bsky.social
Deceased diabetic #kidneydonors: what are the graft and patient outcomes following kidney #transplantation? #CKD
@unityhealthto.bsky.social
@csnscn.bsky.social
doi.org/10.1177/2054...
Figure 1 Hypothesis. CRC, colorectal cancer; dMMR, deficient mismatch repair; HGD, high-grade dysplasia; HP, hyperplastic polyp; LGD, low-grade dysplasia; pMMR, proficient mismatch repair; SSL, sessile serrated lesion; SSL-D, sessile serrated lesion with dysplasia; TSA, traditional serrated adenoma.
From our March issue, "Risk of deficient mismatch repair colorectal cancer and precursors after kidney transplantation: A nationwide study," by Zwart et al
doi.org/10.1016/j.aj...
#KidneyTransplant #ColorectalCancer #Transplantation #Immunosuppression
Does the logistics of normothermic machine perfusion matter in liver transplantation from donation after circulatory death donors is discussed in this paper by Alderete et al. #TXPforAll #Transplantation #OpenAccess tinyurl.com/4zjt47ae
The History of Transplant specialty podcast
🎙️ New Podcast: The History of Transplant
🎧 Listen here! ajthighlights.podbean.com
#Transplantation #TransplantHistory #MedicalHistory
