This image is from Abs Khan and Yuqi Shen’s recent paper. Read the full paper here: www.cell.com/cell-stem-ce....
#Organoids #3DCellCulture #BoneMarrow #Immunology #CellBiology #SciComm
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#BoneMarrow
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🩸 Further insights into anemia management strategies in Myelofibrosis
#Hematology #Myelofibrosis #Anemia #MyeloproliferativeNeoplasms #MPN #BloodDisorders #HemOnc #Oncology #MedEd #MedicalEducation #BoneMarrow #IronOverload #Thrombosis #HEMEHUB
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🩸 Happening next week!
Register: hemehub.org/live-webinars
Submit your cases: hemehub.org/case-submiss...
#Myelofibrosis #MPN #Hematology #BloodCancer #JAKInhibitors #BoneMarrow #Transplantation #HemeHub #BloodDisorders @mayocliniccancer.bsky.social @mayoclinic.org
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🩸 Happening next week!
🔗Register: hemehub.org/live-webinars
💬Case submissions: hemehub.org/case-submiss...
#Myelofibrosis #MPN #Hematology #BloodCancer #JAKInhibitors #BoneMarrow #Transplantation #HemeHub #PatientCare #MedicalEducation #BloodDisorders @mayocliniccancer.bsky.social @mayoclinic.org
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🩸 Join our upcoming session on myelofibrosis featuring insights from Ayalew Tefferi, MD, and Taha Bat, MD!
🔗Register: hemehub.org/live-webinars
💬Submit your cases: hemehub.org/case-submiss...
#Myelofibrosis #MPN #Hematology #BoneMarrow #Transplantation #HemeHub @mayocliniccancer.bsky.social
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🩸Today’s questions!
Swipe to see the answers and their explanations!
#Myelofibrosis #MPN #Hematology #HemeOnc #Ruxolitinib #Selinexor #Pelabresib #JAKInhibitors #Hepcidin #Erythropoiesis #Splenomegaly #BoneMarrow #BloodDisorders #MedEd #ClinicalHematology #MPNResearch #BloodCancer #HEMEHUB
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🩸Facts about Myelofibrosis:
JAK Inhibitor Therapy
#Myelofibrosis #MPN #Hematology #JAKInhibitors #Ruxolitinib #Momelotinib #ACVR1 #Hepcidin #Erythropoiesis #Splenomegaly #BoneMarrow #BloodDisorders #ClinicalHematology #MedEd #HemeOnc #HEMEHUB
@gmpnsf.bsky.social @rarediseaseadvisor.bsky.social
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🩸 Don’t miss our upcoming session on myelofibrosis featuring Ayalew Tefferi, MD, and Taha Bat, MD!
🔗Register: hemehub.org/live-webinars
💬Submit your cases: hemehub.org/case-submiss...
#Myelofibrosis #MPN #Hematology #JAKInhibitors #BoneMarrow #HemeHub @mayocliniccancer.bsky.social @mayoclinic.org
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🩸Additional insights into disease pathogenesis and diagnosis in Myelofibrosis
#Myelofibrosis #PrimaryMyelofibrosis #Hematology #MPN #HemeOnc #MedEd #BoneMarrow #Anemia #Neutrophils #BloodDisorders #HemeTwitter #HemeHub
@mpnjournal.bsky.social @gmpnsf.bsky.social @rarediseaseadvisor.bsky.social
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Deepen your diagnostic expertise with this essential reference from #AmericanRegistryOfPathology.
A must-read for pathologists and trainees.
📚Find out more: tinyurl.com/yc5cs9ep
#Pathology #BoneMarrow
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📢 New in Cell Stem Cell!
Researchers led by Dr. Abdullah Khan at @imm.ox.ac.uk have developed a scalable iPSC-derived #BoneMarrow organoid that models human lympho-myeloid hematopoiesis and disease.
1️⃣ Study: https://bit.ly/3P7lZan
2️⃣ Discussion: https://bit.ly/46sLQQe
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CXCR4hi #CARTcells boost #TumorTracking, #BoneMarrow homing, and persistence, enhancing #Antitumor activity; early trial data in B cell malignancies show multiple complete responses, supporting #CXCR4 modification.
#OpenAccess in #STTT: doi.org/10.1038/s413...
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🩸 Join us for an expert-led session with Ayalew Tefferi, MD, and Taha Bat, MD on patient cases and clinical insights in #myelofibrosis.
➡️Register: hemehub.org/live-webinars
➡️Case submissions: hemehub.org/case-submiss...
#MPN #Hematology #BoneMarrow #MedEd #HemeHub @mayocliniccancer.bsky.social
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🩸 This Month on HemeHub: #Myelofibrosis
Join us as we explore diagnosis, JAK inhibitor therapy, combination & emerging treatments, anemia management, and transplantation in myelofibrosis.
#MPN #Hematology #BoneMarrow #MedEd #HemeHub #BloodDisorders @mayocliniccancer.bsky.social @mayoclinic.org
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Every day, your bone marrow produces ~500 billion blood cells, replacing your entire blood supply about every 120 days.
#FridayFunFact #BoneMarrow #LabSymplified
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Single-cell #multiomics profiling of #CML #bonemarrow shows reduced #CD4 naïve cells, expanded #CD8 terminal effectors, reduced TCR diversity, and altered immune signaling, highlighting CD8 TE cells as key drivers and therapeutic targets.
#OpenAccess: doi.org/10.1016/j.ge...
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Join us in congratulating the award winners from the National Heart, Lung, and Blood Institute, @niaidnews.bsky.social, and the Keystone Symposia Future of Science Fund at #KSHemato26 in Keystone! 👏
#FutureofScience #hematopoiesis #bonemarrow
@bloodgenes.bsky.social @beaudinlab.bsky.social
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#SingleCellTranscriptomics of #bonemarrow in #Type2Diabetes reveals impaired #cytokinesignaling, reduced #osteoclast activity, and diminished Cd36+ precursor differentiation, driven by dysregulated AP-1 transcription factor activity.
#OpenAccess: doi.org/10.1016/j.ge...
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One of the best meals to have on a winter day. This is the #bonemarrow special #pho with a melon tea to drink. The place is called #phohoanggia #foodstagram #viatnamesefood
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🩸 This Month on HemeHub: Multiple Myeloma
Join us as we explore the latest advances in diagnosis, risk assessment, and emerging therapies for multiple myeloma.
Stay tuned for our expert-led session with Paul Richardson, MD & Adeel Khan, MD.
#Hematology #MultipleMyeloma #BoneMarrow #PatientCare
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Scientists show that engineering #CARTcells to overexpress #CXCR4 restores #CXCL12-guided migration, enhances #tumortracking and #BoneMarrow homing, promotes memory persistence, and improves #antitumor efficacy in #BcellLymphoma and #myeloma.
#STTT: doi.org/10.1038/s413...
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#TGFβ1 drives maladaptive #BoneMarrow endothelial repair, impairing #VascularRegeneration and #hematopoietic support; inhibition restores EC and promotes multilineage recovery, underscoring a therapeutic path for regeneration. @pku1898.bsky.social
#STTT: doi.org/10.1038/s413...
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Polycythemia: Types (Primary vs Secondary), CRAB Symptoms, Diagnostics, Treatment & Nursing Interventions
#hematology #medicine #health #nursing #blooddisorders #RBC #thrombosis #bonemarrow #VikaasShandily #nurselife #medstudent #nclex #pathophysiology
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#Chemotherapy alters #GutBacteria, increasing the #MicrobialMetabolite indole-3-propionic acid, which travels to the #BoneMarrow to reduce #immunosuppressive cells and limit #CancerMetastasis.
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Multiple Myeloma: Plasma Cell Cancer, CRAB Symptoms, Labs, Risk Factors | Oncology
#Cancer #oncology #medicine #Nursing #multiplemyeloma #myeloma #bloodcancer #hematology #plasma #bonemarrow #nurselife #medstudent #NCLEX #VikaasShandily
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Scientists reveal that #MesenchymalStromalCell transplantation induces #BoneMarrow neutrophil aggregation to generate #ExtracellularVesicle storms, which balance Th17/Treg cells, drive immune tolerance, and predict therapeutic efficacy in #SLE.
#STTT: doi.org/10.1038/s413...
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A Silent Bone Marrow Shift May Predict Leukemia Years Before It Starts #Science #HealthandMedicine #Oncology #Leukemia #BoneMarrow #CancerResearch
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Gating strategy and immunohistochemistry
Non‑severe #AcquiredAplasticAnemia patients show persistently reduced circulating #Tregs even after #ImmunosuppressiveTherapy, highlighting that combining relative and absolute Treg counts may improve distinction of #BoneMarrow failure syndromes.
Read: doi.org/10.1007/s115...
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💡These findings led to clinical interventions, from preventative care and urgent treatments like #bonemarrow transplant. Detecting genetic conditions earlier reduces the need for late-stage, resource-intensive treatment, supporting #humanhealth.
#PediatricGenomics
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Researchers at the University of Basel developed #BoneMarrow #organoids that recapitulate molecular and cellular features of native endosteal niches, enabling the study of pathophysiological interactions with HSCs.
📝 https://bit.ly/48mU0cH
🗨️ https://bit.ly/48dmghX
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