But we wondered if the epigenetic edits would remain stable during #hematopoiesis, particularly given dramatic changes in DNA methylation during differentiation as shown by @bocklab.bsky.social, @goodell-lab.bsky.social, and others?
🩸Additional facts about transplantation & curative intent in Myelofibrosis
#Myelofibrosis #MF #Hematology #Spleen #BloodCancer #JAKInhibitors #Engraftment #AML #Hematopoiesis #BoneMarrowFibrosis #PatientCare #BloodDisorders #MedEd #HEMEHUB
🚨🧬🩸 Delighted to have this @naturerevgenet.bsky.social review w/ Michael Poeschla published today - Genetic Influences on #hematopoiesis: rdcu.be/e9vlD
👋Our March issue is out!
Cover: #Adipose – #tumor in #immune escape
👉Reviews on: #metabolism #hematopoiesis ; #amnion ; #brain #lipids
🔬 #mitochondria #LipidDroplets #aging #autophagy #mechanobiology #neurodegeneration #ferroptosis #chromatin #metastasis & more!
www.nature.com/ncb/volumes/...
Explore Novogene's case study: CRISPR/dCas9 DNA methylation editing in human HSPCs shows heritable p15 hypermethylation affects haematopoiesis in vivo. See methods, results & implications. #Epigenetics #CRISPR #Hematopoiesis https://tinyurl.com/2n47mrwm
Missed the meeting? Catch it on demand.
The joint Keystone Symposia on Hematopoiesis & Myeloid Cells: Functional Heterogeneity with Therapeutic Promise is now available to watch anytime.
🎥 keysym.us/KSHemato26OD
🎥 keysym.us/KSMyeloid26OD
#KSHemato26 #KSMyeloid26 #hematopoiesis #myeloidcells
Discuss advances in #epigenetics, #immunity and more in the EMBO Workshop "Aged #hematopoiesis & myeloid #leukemia: Molecular medicine insights" in #Kolkata, India, 16–19 Nov 2026.
Deadline: 15 July
https://meetings.embo.org/event/26-hematopoiesis
#EMBOAgedHematopoiesis #EMBOevents 🧪
Delve into recent JEM studies in the fields of #hematopoiesis and #myeloid lineages, incl. the role of neutrophils in myocardial & vascular injury, the characterization of intrarenal myeloid cells, a deeper understanding of the origin & function of #DendriticCells & more: rupress.org/jem/collecti...
A must-listen #Hematopoiesis podcast with so many wisdom pearls from the incredible
@carrawayhetty.bsky.social and #AlfredLee. A thoughtful and high-yield conversation with insights that resonate far beyond the episode. @ash.edu.hematology.org
open.spotify.com/episode/0zVJ...
To my friends who are @keystonesymposia.bsky.social #hematopoiesis and #myeloid meetings— please check out two talks from my group TOMORROW: Ruoqiong Cao on central #trainedimmunity Thursday morning and Arushana Maknojia unravels #microbiome dependent hematopoiesis in the pm! 🔥🔥🔥
Molecular and phenotypic blueprint of human #hematopoiesis links proliferation stress to #StemCell #aging. From Emanuele Lettera et al. @dimiccolab.bsky.social: rupress.org/jem/article/...
📘 In Hematopoiesis and #Myeloid Cells collection: rupress.org/jem/collecti...
#KSMyeloid26 #KSHemato26
Tet2 deficiency–induced expansion of monocyte-derived #macrophages promotes liver #fibrosis. From Jiuxing Feng, Baitong Wu, Yujiang Geno Shi and colleagues: rupress.org/jem/article/...
📘 In #Hematopoiesis and #Myeloid Cells collection: rupress.org/jem/collecti...
#KSMyeloid26 #KSHemato26
Join us in congratulating the award winners from the National Heart, Lung, and Blood Institute, @niaidnews.bsky.social, and the Keystone Symposia Future of Science Fund at #KSHemato26 in Keystone! 👏
#FutureofScience #hematopoiesis #bonemarrow
@bloodgenes.bsky.social @beaudinlab.bsky.social
pDCs amplify tissue-resident memory CD8⁺ T cell responses during viral reinfection. From Elena Hernández-García, Salvador Iborra and colleagues: rupress.org/jem/article/...
📘 In #Hematopoiesis and #Myeloid Cells collection: rupress.org/jem/collecti...
#KSMyeloid26 #KSHemato26
Thymic myeloid cells are heterogenous and include a novel population of transitional #DendriticCells. From Matouš Vobořil, Kristin Hogquist and colleagues: rupress.org/jem/article/...
📘 In #Hematopoiesis and #Myeloid Cells collection: rupress.org/jem/collecti...
#KSMyeloid26 #KSHemato26
#Radiotherapy induces YTHDF2 in #DendriticCells impairing cross-presentation and T cell function, from Dapeng Chen, Chuan He, Hua Laura Liang, Ralph Weichselbaum et al: rupress.org/jem/article/...
📘 In #Hematopoiesis & #Myeloid Cells collection: rupress.org/jem/collecti...
#KSMyeloid26 #KSHemato26
Mechanometabolism instructs hematopoietic stem cell specification, from Paulina Horton, Pamela Wenzel and colleagues: rupress.org/jem/article/...
📘 In #Hematopoiesis and #Myeloid Cells collection: rupress.org/jem/collecti...
#KSMyeloid26 #KSHemato26
A #circadian checkpoint relocates #neutrophils to minimize injury, from Aroca-Crevillén, Hidalgo @drusqui.bsky.social and colleagues: rupress.org/jem/article/...
📘 In #Hematopoiesis and #Myeloid Cells collection: rupress.org/jem/collecti...
#KSMyeloid26 #KSHemato26
Heart of the matter: #Neutrophils, #cancer, and #CardiovascularDisease. Review from Ambreen, McCarthy, Hidalgo, and @adrover.bsky.social: rupress.org/jem/article/...
📘 In #Hematopoiesis and #Myeloid Cells collection: rupress.org/jem/collecti...
#KSMyeloid26 #KSHemato26
A human-mouse atlas of intrarenal myeloid cells identifies conserved disease-associated #macrophages in #lupus #nephritis. From Hoover, Hacohen, Davidson & colleagues: rupress.org/jem/article/...
📘 In #Hematopoiesis & #Myeloid Cells collection: rupress.org/jem/collecti...
#KSMyeloid26 #KSHemato26
XPR1 regulates fetal liver #macrophage development, identity and pyrenocyte clearance. From Sebastian Stifter, Melanie Greter and colleagues: rupress.org/jem/article/...
📘 In #Hematopoiesis and #Myeloid Cells collection: rupress.org/jem/collecti...
#KSMyeloid26 #KSHemato26
See our collection of recent findings in the fields of #hematopoiesis and #myeloid lineages, including the role of #neutrophils in myocardial and vascular injury, the characterization of intrarenal myeloid cells, and more: rupress.org/jem/collecti...
Explore recent findings in the fields of #hematopoiesis and #myeloid lineages, including the role of #neutrophils in myocardial and vascular injury, the characterization of intrarenal myeloid cells, & more, to accompany @keystonesymposia.bsky.social meeting on the topic: rupress.org/jem/collecti...
Thank you to Dr. Vijay Sankaran @bloodgenes.bsky.social
@bostonchildrens.bsky.social for presenting our annual Richard Frisbee, III Grand Rounds Lecture on how human genetic variation can teach us about #hematopoiesis.
@yale-hematology.bsky.social
Online now in Stem Cell Reports! Erythropoietin exposure disrupts B cell development and drives the emergence of myeloid-biased biphenotypic progenitors #lymphopoiesis #hematopoiesis #myelopoiesis https://ow.ly/Po5Q50YacSq
ISSCR | Cell Press | The Gairdner Foundation | SickKids Foundation
RESEARCH PAPER: B-lineage commitment is dependent on a reversible epigenetic switch
By Tingvall-Gustafsson et al., and Mikael Sigvardsson
➡️ https://genesdev.cshlp.org/content/40/3-4/233.full
Linköping University @lunduniversity.bsky.social
#hematopoiesis #Bcell #transcriptionfactor #epigenetics
Meet the Ditadi lab, based at the San Raffaele Telethon Institute for Gene Therapy, in the north-east corner of Milan, Italy. 👇
#BloodCells #Hematopoiesis
thenode.biologists.com/lab-meeting-...
New study analyzes 532 RNA-seq datasets to map promoter activity in #hematopoiesis, providing insights into promoter-mediated regulation and a foundation for targeting promoter-specific mechanisms in disease.
ISSCR
www.cell.com/stem-cell-reports/fullte...
In vivo CRISPR/Cas9 screens identify new regulators of B cell activation and plasma cell differentiation. New study from Lesly Calderón @lesly-calderon.bsky.social, Meinrad Busslinger and colleagues @impvienna.bsky.social: rupress.org/jem/article/...
#Hematopoiesis
🩸More insights on emerging therapies & future directions in Inherited Bone Marrow Failure Syndromes
#AndrogenTherapy #Danazol #Telomeres #BoneMarrowFailure #IBMFS #Eltrombopag #ClonalEvolution #CD117 #Hematopoiesis #StemCellTherapy #Hematology #ClinicalUpdates #MedEd #HEMEHUB
