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Just over a month to go!
The #DayofImmunology webinar, “Regulatory T Cells: Guardians of Immune Balance,” is coming together 🧬

Will we see you there?
https://loom.ly/SY4rF60

#DOI2026 #RegulatoryTCell #Tregs #ImmunologyWithoutBorders

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🙌👏 Congrats on this creative event!
#DayofImmunology #Tregs #RegulatoryTCell

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🎤 #Interview with Carolin Daniel

Prof. Carolin Daniel is the Director of the newly established Institute for Metabolism and Immunology at #HelmholtzMunich.
She strives to cultivate an environment that promotes curiosity-driven research.

👉 t1p.de/zvnao

#Immunology #Metabolism #Tregs #prevention

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Lower frequencies of #Tregs are reported with more impaired behaviors impacting individuals with #autism. 🥼

Scientists explore whether adoptive transfer of Tregs into maternal immune activation offspring recipients could rescue immune activation.

🔗 https://bit.ly/3NCqU2P

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So far in March, we've featured papers on:

• how inflammatory #ILC2 migrate
• engineering #CAR-TCells to restore #checkpoint sensitivity
• capturing the earliest events of #TCell #development
• how certain dietary antigens recognized by #Tregs help mediate #OralTolerance

New content every week!

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🎨 Celebrate the 2026 Day of #Immunology with
@nextgenimmuno.bsky.social!

Join this creative event on 19 March 2026 at the Anna Spiegel Research Building on the AKH Campus.

Open to everyone, come explore #Tregs through art, music & discussions!

👉 Register here: bit.ly/4qSTbj4

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Less than 2 months to go.
April 29 is approaching fast 🏃‍♀️🏃‍♂️🏃

Are you joining the webinar?
Launching a campaign?
Competing for the DoI Awards?

💭 What’s your plan for #DayofImmunology 2026?
https://loom.ly/yWRSIP0

#DOI2026 #RegulatoryTCell #Tregs #ImmunologyWithoutBorders

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Regulatorische T-Zellen: Hilfe bei Allergie, Entzündung und Organabstoßung Die Zellen kontrollieren die Reaktion des Immunsystems und verhindern Schäden durch Selbstangriffe. Forschende arbeiten daran, sie zur Therapie einzusetzen.

Für die Entdeckung der regulatorischen T-Zellen #Tregs wurden drei Forscher:innen 2025 mit dem Medizin-Nobelpreis ausgezeichnet. HZI-Immunologe Jochen Hühn erklärt im @ndr.de, wie Tregs als "Dirigenten" des Immunsystems für eine ausbalancierte Immunantwort sorgen.
www.ndr.de/ndr-text/fer...

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💶 Recently, we told you how to enter the #DayofImmunology Awards. Now here’s why it’s worth it.

Top campaigns in 2026 can win up to EUR 3,000 — plus global recognition.
Swipe for prize details.

📩 info@iuis.org
🔗 https://loom.ly/yWRSIP0
#DOI2026 #Tregs #ImmunologyWithoutBorders #ScienceOutreach

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Tissue-adapted regulatory T cells integrate inflammatory cues to drive intestinal repair following therapy-related injury, highlighting context-specific immune regulation.
doi.org/10.1038/s413...
#Tregs #IntestinalRepair #ImmuneRegulation #Inflammation #GutImmunity

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Tissue Regulatory T Cells FOXP3+ regulatory T cells (Tregs) have well-defined roles in limiting systemic immune responses against diverse stimuli. However, the observation that a subset of Tregs also enter nonlymphoid tissues,...

Our latest review is out, a comprehensive synthesis of #tissue #Tregs. It has been a decade since @annualreviews.bsky.social #immunology last reviewed #TissueTregs, and there have been enormous advances and conceptual leaps forward in the field

www.annualreviews.org/content/jour...

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📢Registration for the #DayofImmunology webinar is open!

🔬Regulatory T Cells: Guardians of Immune Balance
🗓️April 29 at 15:00 CET

💥 Start the buzz & register to save your spot at this rock star webinar featuring outstanding speakers!

🔗 loom.ly/q1XCaxA

#DOI2026 #RegulatoryTCell #Tregs

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🚀 Registration is open.

#DayofImmunology 2026 is underway.
🧬 Regulatory T Cells: Guardians of Immune Balance.
📅 29 April 2026

Sign up for the live webinar and start planning your campaign.
🔗 https://loom.ly/q1XCaxA

#DOI2026 #RegulatoryTCell #Tregs #ImmunologyWithoutBorders

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The image shows a diagram depicting immune activation in primary sclerosing cholangitis, with annotations labeling various tissues, cells, and processes involved in the immune response.

The image shows a diagram depicting immune activation in primary sclerosing cholangitis, with annotations labeling various tissues, cells, and processes involved in the immune response.

🔎Distinct immune signatures define #PSC beyond #IBD

🔸Th17-driven inflammation is upregulated
🔸 #Tregs are reduced vs IBD
🔸Liver: ↑ IL-1β/TNF-α, ↓IL-2/IL-10
🔸Blood: ↑effector T cells and pro-inflammatory cytokines

Read the full article in UEG Journal 👉 https://bit.ly/4pK9LBi

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💡Got an idea that can make an impact this #DayofImmunology 2026?

🌟Together with @iuis-online.bsky.social, #EFIS is proud to recognize the most creative and impactful campaign that our members organize to celebrate #DOI2026 with DoI Awards 🎉

More ℹ️ iuis.org/day-of-immun...

#RegulatoryTCell #Tregs

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💭 Planning a campaign for #DayofImmunology 2026?

Make it count — and get recognised.
The DoI Awards honour bold, creative outreach from IUIS Member Societies & Federations.

📅 Campaigns run around April 29.
📩 Questions? info@iuis.org

#DOI2026 #Tregs #ImmunologyWithoutBorders #ScienceOutreach

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Cellistic launches new iPSC-based platforms to expand immuno-oncology therapies - PharmaTimes New manufacturing technologies aim to accelerate next-generation cell therapy development

#Cellistic #iPSCbasedplatforms #immunooncologytherapies #celltherapydevelopment #GMPmanufacturing #iPSCderivedcelltherapies #immunooncology #regenerativemedicine #EchoT #EchoCardio #EchoEndothelial #allogeneiccelltherapy #EchoNKsystem #celltherapy #autologousTcelltherapies #Tregs
zurl.co/EF2mP

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#Article in #MedComm
Low Dose of #IL_2 Application for Graft-Versus-Host Disease (#GVHD) Prophylaxis Following Haploidentical Stem Cell Transplantation doi.org/10.1002/mco2...

#Tregs #interleukin_2 #NKcell

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Mark your calendars for April 29th as this year's #DayofImmunology webinar highlights the #RegulatoryTCell; the guardians within our immune system!
Learn more👇
#DOI2026 #Tregs #ImmuneBalance

@yefis-immunology.bsky.social @iuis-online.bsky.social

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🧬 Regulatory T cells are the unsung heroes keeping your immune system in check. And this year, they’re the stars of #DayofImmunology.
📅 April 29 is coming fast.
🎥 Catch up on past webinars: https://loom.ly/2L-Vo74
🔗 Learn more: https://loom.ly/yWRSIP0
#DOI2026 #Tregs #ImmunoHub #ImmuneBalance

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🥁 Drum roll, please…
The 2026 #DayofImmunology theme is here:
🧬 Regulatory T Cells: Guardians of Immune Balance
IUIS & EFIS will lead a global campaign + live event on April 29.
🧠 Bold stories. Global reach. And, of course, the #DoIAwards!
Start planning
🔗 https://loom.ly/yWRSIP0
#DOI2026 #Tregs

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Engineered extracellular vesicles reprogram T cells by targeting PD-1 and PHB1 signaling in inflammatory bowel disease - Signal Transduction and Targeted Therapy Signal Transduction and Targeted Therapy - Engineered extracellular vesicles reprogram T cells by targeting PD-1 and PHB1 signaling in inflammatory bowel disease

A #bioengineered #ExtracellularVesicle therapy with #PDL1 and #miR27a3p reprograms T‑cell immunity in #InflammatoryBowelDisease by suppressing Th17 #bioenergetics, expanding #Tregs, reducing inflammation, and preserving gut epithelial integrity.

#STTT: doi.org/10.1038/s413...

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🔥Hot Off the Press | #Tregs detoxify #ammonia through the urea cycle by upregulating #ASL
🔸Anti-PD-1-triggered tumor cell death➡️ammonia released➡️drives resistance by boosting Tregs
💡Ammonia serves as a promising target to suppress Tregs in cancer immunotherapy

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Gut microbiota promotes immune tolerance at the maternal-fetal interface Microbiota-dependent tryptophan-derived indole deficiency is linked to mouse fetal resorption and human recurrent miscarriage. Tryptophan-derived indoles prime MDSCs and RORγt+ Tregs to suppress…

"microbiota-dependent immune tolerance mechanisms that promote fetal development."

#science
#immunology
#Tregs
#microbiota
#tolerance

buff.ly/etkvjWF

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 Gating strategy and 
immunohistochemistry

Gating strategy and immunohistochemistry

Non‑severe #AcquiredAplasticAnemia patients show persistently reduced circulating #Tregs even after #ImmunosuppressiveTherapy, highlighting that combining relative and absolute Treg counts may improve distinction of #BoneMarrow failure syndromes.

Read: doi.org/10.1007/s115...

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In head & neck squamous cell carcinoma, Bcl6 shapes Treg stability + suppressive activity—offering promise for immune-based therapies.
#HNSCC #Immunotherapy #Tregs #CancerImmunology
www.sciencedirect.com/science/arti...

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Researchers reveal that #CigaretteSmoke worsens #CrohnsDisease but protects #UlcerativeColitis by modulating GPR15+ T cells, which amplify harmful Th17 cells in CD yet increase protective #Tregs in UC. #InflammatoryBowelDisease

#OpenAccess in #STTT: doi.org/10.1038/s413...

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Their discovery and achievements have really benefited humanity!

#Tregs

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🔥Hot Off the Press | A study identifies #JMJD1C as a key regulator of tumor #Tregs, a promising selective cancer target.
🧐 Researchers identified #193D7, a potent inhibitor that suppresses #tumor growth without systemic autoimmunity, using the #AI platform #EquiScore.

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