Lente hangt in de lucht op de Boerenmarkt Losser zaterdag 28 maart Lente hangt in de lucht op de Boerenmarkt Losser zaterdag 28 maart

Lente hangt in de lucht op de Boerenmarkt Losser zaterdag 28 maart

#boerenmarkt #pasen #kinderen #feest #cvhoalthakkers #streekproducten #paashaas #cml #paasmarkt #lente #losser #beuningen #delutte #overdinkel #glane

Merck Acquires Terns Pharmaceuticals for $6.7B Merck buys Terns Pharmaceuticals for $6.7B, gaining leukemia drug TERN-701 to offset Keytruda's 2028 patent cliff. Learn what this means for CML treatment.

Merck Acquires Terns Pharmaceuticals for $6.7B
Merck buys Terns Pharmaceuticals for $6.7B, gaining leukemia drug TERN-701 to offset Keytruda's 2028 patent cliff. Learn what this means for CML t...

#MerckTerns #TERN701 #CML #MRK #BiotechMergers
https://scrollworthy.org/trending/terns-pharmaceuticals

Anton Vorobets (@antonvorobets) Watch the Conditional Maximum Loss (CML) presentation from CQF Institute’s Portfolio Management conference. You can now find the replay on CQF Institute’s website under Resources > Videos > Portfolio...

Watch the Conditional Maximum Loss (CML) presentation from CQF Institute’s Portfolio Management conference:

substack.com/profile/1707...

#quant #quantsky #finance #markets #python #investing #conditionalmaximumloss #cml #maximumloss #investment

Day 2199: On Daffodil Day I’m glad to walk 😊 Cancwr awareness is everything #100daysofwalking #cml #365daysofwalking #leukaemia

Operação Lúmen: secretário-geral da Câmara Municipal de Lisboa é um dos detidos por causa de iluminações de Natal Alberto Laplaine Guimarães é considerado suspeito pelo Ministério Público de ter, alegadamente, beneficiado a maior empresa do mercado nos contratos para as luzes de Natal em Lisboa ao longo dos últim...

A #CML é um ninho de criminalidade.

Secretário-geral da Câmara Municipal de Lisboa e militante histórico do CDS, é um dos quatro detidos esta terça-feira na megaoperação da PJ por suspeitas de corrupção.

Interplay Between Psychological Burden, Economic Stress, and Quality of Life in Chronic Myeloid Leukemia Care: An Integrated Analysis | JCO Oncology Practice PURPOSEAs survival rates among patients with chronic myeloid leukemia (CML) have improved significantly, treatment goals have expanded from disease control to optimizing long-term quality of life…

Shift in #CML care in era of 📈 treatment options: many patients still have poor quality of life when experiencing multiple side effects of their TKIs despite excellent disease control. Justifies need for tx-free remissions, wider STAMPi access @jco-asco.bsky.social

ascopubs.org/doi/10.1200/...

Subsidie van provincie voor sterker en toekomstbestendig centrum Losser Subsidie van provincie voor sterker en toekomstbestendig centrum Losser

Subsidie van provincie voor sterker en toekomstbestendig centrum Losser

#gemeentelosser #provincieoverijssel #wethouderlahdo #wethouder #cml #centrummanagementlosser #subsidie #ondernemers #biz #bedrijveninvesteringszone #losser #beuningen #delutte #overdinkel #glane #glanebeek #twente

🔬 In our latest issue, we invite you to discover the Editor's Choice article exploring deubiquitination mechanism involved in resistance to tyrosine kinase inhibitors in chronic myeloid leukemia, accompanied by an insightful Commentary.
Discover, here ➡️ buff.ly/jdODi5z
#CML #ubiquitin #TKI

Deep learning analysis of over 1500 #CML marrow slides reveals overlooked cytomorphologic features that strongly predict TKI response. A new Morphoclinical model markedly outperforms current risk scores, supporting more precise frontline therapy selection in CML.  👉https://bit.ly/4rP6imf

I decided to do a DHCPv6 lab. Router "iol-0" is the DHCPv6 server and is supplying IPv6 addresses to 2 Linux PCs. I had to install DHCPCD on the Alpine Linux PC. I also had to modify the NETPLAN .yaml file on the Ubuntu PC to handle DHCPv6.

#cisco #ciscomodelinglabs #cml #IPV6 #DHCPv6

This is a simple DHCP Lab which uses VLANs. Anyone doing the CCNA exam should know this stuff. I have VLAN10 and VLAN20 encapsulated and trunked up to the router. Very simple for those getting into the field.

#cisco #ciscomodelinglabs #cml #DHCP #VLAN #TRUNK

I modified my DHCP lab to show a DHCP Relay Agent (iol-1) forwarding DHCP information to the server (iol-0). . The "ip helper-address 10.0.1.1" command on iol-1 is used to initiate forwarding to the server.

#cisco #ciscomodelinglabs #cml #DHCP

Here's another look at DHCP in action. This time Router "iol-0" is offering addresses to two subnets. The attached packet capture also shows "DORA" - Discover, Offer, Request and Acknowledge in action.

#cisco #ciscomodelinglabs #cml #DHCP

I look forward to presenting at CQF Institute’s Portfolio Management in Quant Finance conference next week.

I will present from 15:10 to 15:45 (GMT) according to the schedule below.

Read more and register here: cqfinstitute.org/events/confe...

#quant #finance #markets #investment #tailrisk #cml

Enliven Therapeutics Shares Encouraging Financial Results and Future Clinical Trial Plans Enliven Therapeutics recently reported its financial results for 2025 and provided insights into its promising new drug developments and clinical trials, paving the way for future growth.

Enliven Therapeutics Shares Encouraging Financial Results and Future Clinical Trial Plans #United_States #CML #Boulder #Enliven_Therapeutics #ELVN-001

My story was published on the @bloodcancerunited.bsky.social website 😊 Next Wednesday, it’s 26 yrs since I heard those fateful words, “You have Leukemia.” I’m still here telling my story 🧡💚

bloodcancerunited.org/about-us/sto...

pages.lls.org/ltn/chi/Metr...

#cml #bmt #ltn #michellessunrisecrew

Single-cell #multiomics profiling of #CML #bonemarrow shows reduced #CD4 naïve cells, expanded #CD8 terminal effectors, reduced TCR diversity, and altered immune signaling, highlighting CD8 TE cells as key drivers and therapeutic targets.

#OpenAccess: doi.org/10.1016/j.ge...

Conditional Maximum Loss Article This post contains the latest version of the Conditional Maximum Loss Portfolio Optimization article by Kristensen and Vorobets (2026).

An updated version of the Conditional Maximum Loss (CML) Portfolio Optimization article.

Laura Kristensen and I have recently added some minor clarifications.

Find the latest version of the article and its Python code below.

#quant #quantsky #finance #markets #python #investment #risk #cml

Anton Vorobets (@antonvorobets) Understanding the Fully General Investment Framework (FGIF). The name comes from the fact that the market is represented by fully general Monte Carlo simulation paths. These can contain plain-vanill...

Understanding the Fully General Investment Framework (FGIF):

substack.com/profile/1707...

#quant #quantsky #finance #markets #python #investing #investment #cvar #cml #tailrisk

Foundational Mean-Variance Problems February 2026 edition of the Portfolio Construction newsletter, summarizing the foundational problems with variance-based investment approaches.

This newsletter tells a story that I have told many times. Still, I present new perspectives here.

At the end, there is the usual popular posts recap. Make sure to check it out :-)

#quant #quantsky #finance #markets #python #investing #investment #data #risk #cvar #cml

Conditional Maximum Loss Portfolio Optimization This article summarizes the new Conditional Maximum Loss (CML) investment risk measure and presents an exclusive risk budgeting Python case study.

Conditional Maximum Loss (CML) is a game changer for path-dependent tail risk optimization.

This article introduces a new investment risk measure specifically designed for fully general Monte Carlo path simulations.

#quant #quantsky #finance #markets #python #investing #investment #cvar #cml

In this Review authors discuss that atypical #CML has sig. dx challenges, diverse mutations & no standard of care, stressing need for better prognostic tools & confirm that allogeneic transplant remains the sole curative therapy, w/ targeted agents under investigation👉https://bit.ly/3XL9xOM

New Study Offers Hope for Better Treatment Strategies: Understanding Blast Phase Chronic Myeloid Leukemia | Cancer News A Cleveland Clinic leukemia expert explains findings from a multicenter study on blast phase CML, exploring treatment strategies, TKIs, transplantation, and global access challenges.

A new multicenter study led by Dr. Akriti Jain sheds light on how blast phase CML is currently treated in the U.S. and which strategies may offer the best outcomes: binaytara.org/cancernews/a...
#LeukemiaResearch #CML #ASH2025 #Hematology #CancerCare #Binaytara

Aftrap eerste Boerenmarkt Losser 2026  Aftrap eerste Boerenmarkt Losser 2026 

Aftrap eerste Boerenmarkt Losser 2026 

#boerenmarkt #horeca #markt #centrumlosser #cml #losser #beuningen #delutte #overdinkel #glane #lonneker #glanerbrug #gronau

We reflect on a key breakthrough in the treatment of #CML with Dr. Jorge Cortes, who has been involved in the development of #TKIs since the early days.

👉 buff.ly/nqiq2ZY

#CancerTreatments

Enliven Therapeutics Reports Encouraging Progress for ELVN-001 in CML Treatment and Sets 2026 Goals Enliven Therapeutics shares promising initial Phase 1b results for ELVN-001, indicating its potential as a leading treatment for chronic myeloid leukemia, and outlines significant milestones for 2026.

Enliven Therapeutics Reports Encouraging Progress for ELVN-001 in CML Treatment and Sets 2026 Goals #USA #CML #Boulder #Enliven_Therapeutics #ELVN-001

Single-cell sequencing maps expanded and diverse T-cell subsets in the CML bone marrow microenvironment, giving insight into immune dysregulation.
#CML #SingleCell #TCells #CancerImmunity
www.sciencedirect.com/science/arti...

Just testing out a new screen recorder. May need to lower the resolution a bit. Works well though. Have a look:

👇👇👇
youtu.be/g5RI9vnYwWk

#cisco #ciscomodelinglabs #cml

Sutterella species promote MyD88/Trif-dependent cytotoxic T cell exhaustion, thereby impairing anti-leukemic immunity and accelerating #CML progression @cp-cellreports.bsky.social
www.cell.com/cell-reports...

One cell at a time — A decade of exploring chronic myeloid leukaemia stem cells | The Stellenbosch Institute for Advanced Study For 25 years, the Stellenbosch Institute for Advanced Study (STIAS) has cultivated a unique environment where unexpected connections lead to groundbreaking insights.

Why #CML returns after treatment is central to Göran Karlsson’s research @lundstem.bsky.social. Using single-cell genomics, he studies the cancer stem cells behind relapse. During a STIAS fellowship in South Africa, he’s working to make this data globally accessible.

www.stias.ac.za/news/one-cel...