New Study Offers Hope for Better Treatment Strategies: Understanding Blast Phase Chronic Myeloid Leukemia | Cancer News A Cleveland Clinic leukemia expert explains findings from a multicenter study on blast phase CML, exploring treatment strategies, TKIs, transplantation, and global access challenges.

A new multicenter study led by Dr. Akriti Jain sheds light on how blast phase CML is currently treated in the U.S. and which strategies may offer the best outcomes: binaytara.org/cancernews/a...
#LeukemiaResearch #CML #ASH2025 #Hematology #CancerCare #Binaytara

Chromatin Accessibility Shapes Developmental-Specific Lineage Plasticity in Hematopoiesis Cell differentiation is governed by dynamic changes in chromatin accessibility, and its dysregulation underlies multiple disease states. Prior to birth, development of the hematopoietic system constit...

Don’t miss our new preprint!
We mapped chromatin accessibility in human first-trimester HSPCs, revealing key fetal vs adult differences in hematopoiesis.
🔗 doi.org/10.64898/202...
#Hematopoiesis #StemCells #Chromatin #Epigenetics #LeukemiaResearch

We are grateful for all of the researchers who are making a difference in the lives of so many people impacted by leukemia. Happy Thanksgiving from the Leukemia Research Foundation.
#LeukemiaResearch #ThankYouResearchers

Investigation of the Expression of P-Element-Induced Wimpy Testis-Interacting Rnas in Human Acute Myeloid Leukemia Research found two small RNAs are more active in leukemia, potentially aiding early diagnosis. #LeukemiaResearch #Biomarkers

Research found two small RNAs are more active in leukemia, potentially aiding early diagnosis. #LeukemiaResearch #Biomarkers
www.rimpacts.com/rd/p?c=10160...

This study demonstrates that circ_0012152 promotes #AML cell proliferation through the miR-652-3p/SOX4 axis and serves as an independent poor prognostic factor for overall survival. #LeukemiaResearch #medsky

Read more: link.springer.com/article/10.1...

MERIT Award Fuels Pediatric Leukemia Research Exploring reasons behind treatment resistance in leukemia.

Dr. Matt Witkowski has received an R37 MERIT award to extend his leukemia research looking at how to improve treatment outcomes for pediatric cancer patients who relapse after advanced therapies. #LeukemiaResearch #PediatricCancer #OncSky

The Leukemia Research Foundation announces 2025-2027 research grant recipients Northfield, IL - The Leukemia Research Foundation is pleased to announce the recipients of the 2025-2027 New Investigator Research Grant Program. Grants

We’re thrilled to announce the 2025–2027 New Investigator Research Grant recipients—13 outstanding scientists from across the country who are pushing the boundaries of leukemia research.

Meet the 2025–2027 awardees: bit.ly/474sfGP

#LeukemiaResearch #ScientificDiscovery #FundingtheFuture

Three researchers receive Barncancerfonden funding to investigate the causes of childhood leukemia Lund University. This spring Barncancerfonden, the Swedish Childhood Cancer Foundation, awarded SEK 64 million to 29 researchers across the country. The funding includes positions of up to six years f...

🎗️What causes childhood leukemia to develop?

With funding from Barncancerfonden, 3 early-career researchers at Lund Stem Cell Center are investigating the origins & progression of the disease.

Read more in our full Q&A:
www.stemcellcenter.lu.se/article/thre...

#ChildhoodCancer #LeukemiaResearch

open.substack.com/pub/stefanodangello/p/to...
#BloodCancer #LeukemiaAwareness #CancerFighter #LeukemiaSurvivor #FightLeukemia #CancerWarrior #HopeForLeukemia #LeukemiaResearch #LeukemiaSupport #EndLeukemia

Do you have Acute Myeloid Leukemia? Would you participate in an Advisory Board? Tell us about your journey, Quality of Life, Treatments with AML.
For more details, email us at: admin@healcanada.org
#AcuteMyeloidLeukemia #LeukemiaAwareness #CancerSupport #PatientJourney #LeukemiaResearch #AML

Featured today by @MSKLibrary: Assessing AML-based risk criteria in patients with accelerated/blast-phase MPN treated with less-intensive therapy dx.doi.org/10.1182/bloo...

#MPNResearch #AMLInsights #LeukemiaResearch #RiskStratification #LessIntensiveTherapy #BlastPhaseMPN #PrecisionOncology

Exciting T-ALL research from The #FASEBJournal. 🔬 Scientists discovered how to force leukemia cells to "grow up" and die naturally using KLF4 protein. Drug APTO-253 shows promise for gentler childhood cancer treatments.
Read full study: buff.ly/nl3jA0d
#LeukemiaResearch #PedatricCnacer

Dr. Maggie Ferris dives into AML biology:
🧬 RXR & KMT2A/C play key roles
⚡️ ATRA works for acute promyelocytic leukemia
💡 MENIN inhibition strategies for MLL-rearranged AML
Can we combine ATRA + Bexarotene?
#LeukemiaResearch #PedsOnc #AML

📢 We’re heading to Dublin!

Irmela Jeremias will be attending the 4th Translational Research Conference: Acute Lymphoblastic Leukaemia (ALL).

We’re excited to share our latest research during the poster session.

#ESHALL2025 #LeukemiaResearch #CRISPR #PDXmodels #TranslationalResearch

Featured today by @MSKLibrary: Mis-splicing-derived neoantigens and cognate TCRs in splicing factor mutant leukemias dx.doi.org/10.1016/j.ce...

#Neoantigens #LeukemiaResearch #CancerImmunotherapy #TCellReceptors #PrecisionOncology #TumorImmunology #CancerGenomics #TargetedTherapies

Reprogramming Leukemia: A New Frontier in AML Treatment Scientists reprogram leukemia cells to combat AML—discover the groundbreaking therapy offering new hope.

Scientists reprogram leukemia cells to combat AML—discover the groundbreaking therapy offering new hope. #LeukemiaResearch #CancerTherapy #AMLBreakthrough

Hidden Role of Key Protein Could Transform Leukemia Treatment Northwestern researchers discovered a hidden metabolic role for Menin in leukemia—offering a powerful new target for more effective, personalized treatments.

A key protein has a hidden role fueling leukemia. Scientists say this discovery could lead to smarter, more effective treatments. #LeukemiaResearch #CancerBreakthrough #TargetedTherapies

MPI-NAT Seminar: Targeting epigenetic regulators in leukemia development 2025, Max-Planck-Gesellschaft

Don't miss Hannah Uckelmann's talk today on targeting epigenetic regulators in leukemia development! ▶️ At 3pm @mpi-nat.bsky.social Join us for a compelling session! @hannahuckelmann.bsky.social #leukemiaresearch #epigenetics

Longitudinal omics data and preclinical treatment suggest the proteasome inhibitor carfilzomib as therapy for ibrutinib-resistant CLL | Nature Communications Chronic lymphocytic leukemia is a malignant lymphoproliferative disorder for which primary or acquired drug resistance represents a major challenge. To investigate the underlying molecular mechanisms, we generate a mouse model of ibrutinib resistance, in which, after initial treatment response, relapse under therapy occurrs with an aggressive outgrowth of malignant cells, resembling observations in patients. A comparative analysis of exome, transcriptome and proteome of sorted leukemic murine cells during treatment and after relapse suggests alterations in the proteasome activity as a driver of ibrutinib resistance. Preclinical treatment with the irreversible proteasome inhibitor carfilzomib administered upon ibrutinib resistance prolongs survival of mice. Longitudinal proteomic analysis of ibrutinib-resistant patients identifies deregulation in protein post-translational modifications. Additionally, cells from ibrutinib-resistant patients effectively respond to several proteasome inhi

Carfilzomib might be key for ibrutinib-resistant CLL! Mouse model shows aggressive relapse. Omics: exon, transcript, proteome data back it up. #LeukemiaResearch PMID:39863584, Nat Commun 2025, @NatureComms https://doi.org/10.1038/s41467-025-56318-7 #Medsky 🧪

🏃‍♀️🏃‍♂️ Attending #ASCO25?

🌅 Start your day along Chicago's beautiful lakefront—all while supporting life-saving #leukemiaresearch.

📅 When: Saturday, May 31 at 8:30 AM
📍 Where: Montrose Harbor, Chicago

🔗 Sign up now through the link in our bio.

#LaceUp4Leukemia #Cancer #Oncology

OncoInfluencers to Follow on Social Media: Fadi Haddad - OncoDaily OncoInfluencers to Follow on Social Media: Fadi Haddad / cancer, Fadi Haddad, Leukemia Research, LinkedIn, OncoDaily, oncoinfluencer, Oncoinfluencers to

OncoInfluencers to Follow on Social Media: Fadi Haddad
@mdanderson.bsky.social

oncodaily.com/career/fadi-...

#Cancer #LeukemiaResearch #LinkedIn #OncoDaily #Oncoinfluencer #OncoinfluencersToFollow #Oncology #MDAnderson #Medicine #Health