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Anesthesiology and Critical Care Transplant Topics on Journal Watch Presented by the ISHLT Early Career and Trainee Committee, this month's ISHLT Journal Watch explores topics in critical care and transplant-related topics in anesthesiology.

This month's #ISHLTJournalWatch features studies in critical care and transplant anesthesiology. Brigitte Hollander of Auckland City Hospital is the guest editor for the issue.

#medsky #pulmsky #transplantsky

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The final study for Feb's #ISHLTJournalWatch was reviewed by Baharan Zarrabian of Duke, who explores Muhtadi Alnababteh's study on whether early post-txp recipient tissue injury can predict mortality or #allograft dysfunction in #LungTransplant.

#pulmsky #medsky #transplantsky

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Next up in last month's #ISHLTJournalWatch, Alexandra Mihai reviews a study from @jhlt.bsky.social on whether endothelin-1 expression in #PEA specimens can predict #PH in #CTEPH patients.

#pulmsky #cardiosky #medsky #transplantsky

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The second study in #ISHLTJournalWatch for February comes from @jimmunol.bsky.social and is presented by Nicole Chrysler, HBSc.

The paper explores the immunologic effects of pre-transplant IL-2 complex therapy in murine models.

#transplantsky #medsky #cardiosky

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The February #ISHLTJournalWatch highlights topics in cardiothoracic transplant research and immunology, edited by Rupa Kanchi.🔬

The issue features Lauren East, Nicole Chrysler, Alexandra Mihai, and Baharan Zarrabian.

#ISHLT #MedSky #transplantsky

https://bit.ly/4tS2dzw

#ISHLT #ISHLTEarlyCareer

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Pharmacy in Heart and Lung Transplant: The Latest Studies in ISHLT Journal Watch The first Journal Watch of 2026 explores topics in transplant pharmacy, including valganciclovir for CMV, daratumumab monotherapy, and renal sparing in heart transplant recipients.

The January #ISHLTJournalWatch focuses on topics in #transplant #pharmacy, edited by Colleen Hutchinson. 💊

Topics include the NUDT16 genotype, #daratumumab monotherapy, & early mammalian target of rapamycin inhibitor (#mTORi).

🔗 www.ishlt.org/about/news-d...

#TransplantSky #PharmSky

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The fourth slide of December 2025's ISHLT Journal Watch, reviewing the study "CD26/DPP-IV inhibitors and associations with chronic lung allograft dysfunction in a multicenter cohort." A more screenreader friendly version of the issue can be found at https://www.ishlt.org/docs/default-source/journal-watch/202512_journalwatch_pulm_dec2025.pdf

The fourth slide of December 2025's ISHLT Journal Watch, reviewing the study "CD26/DPP-IV inhibitors and associations with chronic lung allograft dysfunction in a multicenter cohort." A more screenreader friendly version of the issue can be found at https://www.ishlt.org/docs/default-source/journal-watch/202512_journalwatch_pulm_dec2025.pdf

December's #ISHLTJournalWatch closes with Zsofia Rosselli's review of a manuscript from @jhlt.bsky.social on whether gliptins can moderate #CLAD. This multicenter cohort implies association, but requires further study.

#pulmsky #ISHLT #medsky #pharmsky

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The third slide of December 2025's ISHLT Journal Watch, reviewing the study "Outcomes of Lung Transplantation for end stage lung disease with connective tissue disease: a systematic review and meta-analysis." A more screenreader friendly version of the issue can be found at https://www.ishlt.org/docs/default-source/journal-watch/202512_journalwatch_pulm_dec2025.pdf

The third slide of December 2025's ISHLT Journal Watch, reviewing the study "Outcomes of Lung Transplantation for end stage lung disease with connective tissue disease: a systematic review and meta-analysis." A more screenreader friendly version of the issue can be found at https://www.ishlt.org/docs/default-source/journal-watch/202512_journalwatch_pulm_dec2025.pdf

Continuing #pulmsky studies in December's #ISHLTJournalWatch, Muhammad Hayat-Syed of @bcmhouston.bsky.social highlights a study on the distinctions between short- and long-term outcomes for #lungtxp patients with connective tissue disease.

#transplantsky #surgerysky

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The second slide of December 2025's ISHLT Journal Watch, reviewing the study "Cell-free DNA in Ex-Vivo Lung Perfusate is Associated With Low-Quality Lungs and Lung Transplant Outcome." A more screenreader friendly version of the issue can be found at https://www.ishlt.org/docs/default-source/journal-watch/202512_journalwatch_pulm_dec2025.pdf

The second slide of December 2025's ISHLT Journal Watch, reviewing the study "Cell-free DNA in Ex-Vivo Lung Perfusate is Associated With Low-Quality Lungs and Lung Transplant Outcome." A more screenreader friendly version of the issue can be found at https://www.ishlt.org/docs/default-source/journal-watch/202512_journalwatch_pulm_dec2025.pdf

Next in #ISHLTJournalWatch, Alex Dragnich reviews a study from @jhlt.bsky.social—can #cellfreeDNA in #EVLP perfusate reflect #lung quality and affect the decision to use in #transplantation?

@sirusjj.bsky.social

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ISHLT Early Career-Led Literature Review in Pulmonology The December 2025 issue of ISHLT's Journal Watch explores topics in pulmonology, advanced lung failure, and transplant.

The December #ISHLTJournalWatch highlights pulmonology research, edited by @sirusjj.bsky.social.

Topics include gliptins and #CLAD, #cfDNA in #EVLP perfusate, lung allocation strategy, and #connectivetissue diseases in #lungtx.

#ISHLT #pulmsky #transplantsky

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The third slide from the November 2025 issue of Journal Watch, titled "Maribavir for refractory cytomegalovirus (CMV) infection (with or without resistance) in solid organ transplant recipients:
Subgroup analysis of the phase 3 randomized SOLSTICE study" For a more screenreader friendly version, the full issue PDF is at https://www.ishlt.org/docs/default-source/journal-watch/202511_journalwatch_id_nov2025.pdf.

The third slide from the November 2025 issue of Journal Watch, titled "Maribavir for refractory cytomegalovirus (CMV) infection (with or without resistance) in solid organ transplant recipients: Subgroup analysis of the phase 3 randomized SOLSTICE study" For a more screenreader friendly version, the full issue PDF is at https://www.ishlt.org/docs/default-source/journal-watch/202511_journalwatch_id_nov2025.pdf.

Closing out November's #ISHLTJournalWatch, @sarawinndong.febrilepodcast.com reviews a study from @jhlt.bsky.social on the use of #Maribavir for #CMV infection in SOT recipients—an important addition to the toolbox in treating this infection in #transplant recipients.

#TransplantSky #IDSky #MedSky

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The second slide from the November 2025 issue of Journal Watch, titled "Tolerability and clinical efficacy of letermovir for primary cytomegalovirus prophylaxis after heart transplantation" For a more screenreader friendly version, the full issue PDF is at https://www.ishlt.org/docs/default-source/journal-watch/202511_journalwatch_id_nov2025.pdf.

The second slide from the November 2025 issue of Journal Watch, titled "Tolerability and clinical efficacy of letermovir for primary cytomegalovirus prophylaxis after heart transplantation" For a more screenreader friendly version, the full issue PDF is at https://www.ishlt.org/docs/default-source/journal-watch/202511_journalwatch_id_nov2025.pdf.

On #ISHLTJournalWatch this month, Brennan Collis reviews a paper from @jhlt.bsky.social on the clinical efficacy and tolerability of #letermovir for #CMV prophylaxis after #HeartTx.

#CardioSky #TransplantSky #IDsky #MedSky

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The first slide from the November 2025 issue of Journal Watch, titled "Epidemiology and impact of device-specific infections on patients receiving left ventricular assist devices" For a more screenreader friendly version, the full issue PDF is at https://www.ishlt.org/docs/default-source/journal-watch/202511_journalwatch_id_nov2025.pdf.

The first slide from the November 2025 issue of Journal Watch, titled "Epidemiology and impact of device-specific infections on patients receiving left ventricular assist devices" For a more screenreader friendly version, the full issue PDF is at https://www.ishlt.org/docs/default-source/journal-watch/202511_journalwatch_id_nov2025.pdf.

In #ISHLTJournalWatch this month, @haithamalaithan.bsky.social reviews a paper from #JHLTOpen led by Amit Iyengar exploring the epidemiology and impact of device-specific infections on patients with #LVADs.

#medsky #cardiosky #ISHLT

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The latest in transplant Infectious Disease on ISHLT Journal Watch In the November 2025 issue of ISHLT Journal Watch, four early career clinicians explore topics in infectious diseases in advanced heart and lung failure.

November's #ISHLTJournalWatch highlights topics in #InfectiousDisease in heart/lung failure.

Led by @binni-id.bsky.social, the issue features @haithamalaithan.bsky.social, Brennan Collis, and @sarawinndong.febrilepodcast.com.

#IDSky #TransplantSky #MedSky

www.ishlt.org/about/news-d...

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Thoracic Transplant Pathology on This Month's ISHLT Journal Watch In October's ISHLT Journal Watch, transplant pathologists review recent literature on dd-cf-DNA, CAV, and ALAD.

This month on #ISHLTJournalWatch will be interesting to #pathsky and #transplantsky alike: the latest topics in #transplant #pathology, gathered and reviewed by #ISHLT early career members.

www.ishlt.org/about/news-d...

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The fourth slide from the September 2025 issue of Journal Watch, titled "Pig-to-human lung xenotransplantation into a brain-dead recipient." For a more screenreader friendly version, the full issue PDF is at https://www.ishlt.org/docs/default-source/journal-watch/2025-09-journalwatch-ctsurgery.pdf.

The fourth slide from the September 2025 issue of Journal Watch, titled "Pig-to-human lung xenotransplantation into a brain-dead recipient." For a more screenreader friendly version, the full issue PDF is at https://www.ishlt.org/docs/default-source/journal-watch/2025-09-journalwatch-ctsurgery.pdf.

In the final study from last month's #CTSurgery #ISHLTJournalWatch, Anna Niroomand reviews the latest literature in @naturemedicine.bsky.social on pig-to-human #xenotransplantation of the #lung. 🫁

#LungTx #ISHLT #TransplantSky #PulmSky

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In last month's #ISHLTJournalWatch, #KatharinaFetten reviews a study on the association of agonal phase duration with heart utilization & post-transplant outcomes in #DCD #HeartTransplantation. 🫀

#ISHLT #CardiogenicShock #TransplantSky

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In the second study for #ISHLTJournalWatch last month, #RamDuvuru reviews a 5-year study on the outcomes of #DCD #HeartTransplantation. 🫀

#ISHLT #CardiogenicShock #TransplantSky

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Headshots of the five early career professionals involved in the September Issue of ISHLT Journal Watch: Ram Duvuru, Katharina Fetten, Kevin Koomalsingh, Daniel Laskey, and Anna Niroomand. 

Text: 
ISHLT Journal Watch
September 2025
Cardiothoracic Surgery
Current papers, reviewed and presented by Early Career professionals.

Headshots of the five early career professionals involved in the September Issue of ISHLT Journal Watch: Ram Duvuru, Katharina Fetten, Kevin Koomalsingh, Daniel Laskey, and Anna Niroomand. Text: ISHLT Journal Watch September 2025 Cardiothoracic Surgery Current papers, reviewed and presented by Early Career professionals.

This month on #ISHLTJournalWatch, issue editor Kevin Koomalsingh collects reviews of recent #CardiothoracicSurgery research from #ISHLTEarlyCareer professionals. Topics include #LungTxp in patients w/lesions, #DCD #HeartTxp, and #Xenotransplantation.

#PulmSky #CardioSky #SurgerySky #TransplantSky

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The last slide from the August 2025 issue of Journal Watch, titled "Daratumumab monotherapy as a desensitization strategy prior to cardiac transplantation." For a more screenreader friendly version, the full issue PDF is at https://www.ishlt.org/docs/default-source/journal-watch/2025-08-journalwatch-cardiology.pdf.

The last slide from the August 2025 issue of Journal Watch, titled "Daratumumab monotherapy as a desensitization strategy prior to cardiac transplantation." For a more screenreader friendly version, the full issue PDF is at https://www.ishlt.org/docs/default-source/journal-watch/2025-08-journalwatch-cardiology.pdf.

The final study of last month's #ISHLTJournalWatch in #cardiology is from @jhlt.bsky.social.

#HasanSiddiqi reviews a study exploring #Daratumumab monotherapy as a #desensitization strategy prior to #HeartTx.

#cardiosky #transplantsky

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The third slide from the August 2025 issue of Journal Watch, titled "Mavacamten in Patients With Hypertrophic Cardiomyopathy Referred for Septal Reduction: Week 128 Results From VALOR-HCM." For a more screenreader friendly version, the full issue PDF is at https://www.ishlt.org/docs/default-source/journal-watch/2025-08-journalwatch-cardiology.pdf.

The third slide from the August 2025 issue of Journal Watch, titled "Mavacamten in Patients With Hypertrophic Cardiomyopathy Referred for Septal Reduction: Week 128 Results From VALOR-HCM." For a more screenreader friendly version, the full issue PDF is at https://www.ishlt.org/docs/default-source/journal-watch/2025-08-journalwatch-cardiology.pdf.

In last month's #ISHLTJournalWatch, #BhanuRamachandran reviews a study led by Milind Y. Desai on the use of #Mavacamten in patients with obstructive hypertrophic #cardiomyopathy ( #oHCM ). Can Mavacamten allow clinicians to defer or avoid SRT use in these patients?

#ISHLT #CardioSky #TransplantSky

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The second slide from the August 2025 issue of Journal Watch, titled "Early Intra-Aortic Balloon Support for Heart Failure-Related Cardiogenic Shock: A Randomized Clinical Trial." For a more screenreader friendly version, the full issue PDF is at https://www.ishlt.org/docs/default-source/journal-watch/2025-08-journalwatch-cardiology.pdf.

The second slide from the August 2025 issue of Journal Watch, titled "Early Intra-Aortic Balloon Support for Heart Failure-Related Cardiogenic Shock: A Randomized Clinical Trial." For a more screenreader friendly version, the full issue PDF is at https://www.ishlt.org/docs/default-source/journal-watch/2025-08-journalwatch-cardiology.pdf.

In the second study for #ISHLTJournalWatch last month, Max Berrill reviews a randomized #clinicaltrial from JACC about early #IABP for #HF-related #CardiogenicShock.

#CardioSky #TransplantSky

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The fourth slide from the July 2025 issue of Journal Watch, titled "EDITORIAL SPOTLIGHT: Pediatric heart transplantation in donation after circulatory death: is it a feasible reality?--in time, yes!" For a more screenreader friendly version, the full issue PDF is at https://www.ishlt.org/docs/default-source/journal-watch/2025-07-journalwatch-pediatrics.pdf

The fourth slide from the July 2025 issue of Journal Watch, titled "EDITORIAL SPOTLIGHT: Pediatric heart transplantation in donation after circulatory death: is it a feasible reality?--in time, yes!" For a more screenreader friendly version, the full issue PDF is at https://www.ishlt.org/docs/default-source/journal-watch/2025-07-journalwatch-pediatrics.pdf

Before Aug's #ISHLTJournalWatch comes out next week, finish reading the July #pediatrictransplant issue! The final slide of the issue spotlights an editorial on #pediatric #DCD.

When will it be a feasible reality?
How can centers expand access to #HeartTx?
What guidelines should pediatricians read?

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The third slide from the July 2025 issue of Journal Watch, titled "Pediatric heart transplantation within the Scandiatransplant region--a multinational observational study spanning 38 years." For a more screenreader friendly version, the full issue PDF is at https://www.ishlt.org/docs/default-source/journal-watch/2025-07-journalwatch-pediatrics.pdf

The third slide from the July 2025 issue of Journal Watch, titled "Pediatric heart transplantation within the Scandiatransplant region--a multinational observational study spanning 38 years." For a more screenreader friendly version, the full issue PDF is at https://www.ishlt.org/docs/default-source/journal-watch/2025-07-journalwatch-pediatrics.pdf

Up next on #ISHLTJournalWatch: Multinational observations on #pediatric #HeartTx over a 38 year span in Nordic countries. In this time frame, transplant volume increased, waitlist mortality reduced, and #MCS use increased.

#ISHLT #CardioSky #TransplantSky

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The first slide from the July 2025 issue of Journal Watch, titled "Contemporary outcomes of mechanical circulatory support using paracorporeal continuous flow pump in children: A report from the ACTION learning network." For a more screenreader friendly version, the full issue PDF is at https://www.ishlt.org/docs/default-source/journal-watch/2025-07-journalwatch-pediatrics.pdf

The first slide from the July 2025 issue of Journal Watch, titled "Contemporary outcomes of mechanical circulatory support using paracorporeal continuous flow pump in children: A report from the ACTION learning network." For a more screenreader friendly version, the full issue PDF is at https://www.ishlt.org/docs/default-source/journal-watch/2025-07-journalwatch-pediatrics.pdf

The 2nd study for July #ISHLTJournalWatch is an ACTION study assessing clinical outcomes in #pediatric patients supported on #paracorporeal continuous flow (pCF) pumps. 78% of children on pCF VADs had positive outcomes, but patients with #CHD had worse outcomes.

#ISHLT #MCS #VADs #pediatricHF

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