This month's #ISHLTJournalWatch features studies in critical care and transplant anesthesiology. Brigitte Hollander of Auckland City Hospital is the guest editor for the issue.
#medsky #pulmsky #transplantsky
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The final study for Feb's #ISHLTJournalWatch was reviewed by Baharan Zarrabian of Duke, who explores Muhtadi Alnababteh's study on whether early post-txp recipient tissue injury can predict mortality or #allograft dysfunction in #LungTransplant.
#pulmsky #medsky #transplantsky
Next up in last month's #ISHLTJournalWatch, Alexandra Mihai reviews a study from @jhlt.bsky.social on whether endothelin-1 expression in #PEA specimens can predict #PH in #CTEPH patients.
#pulmsky #cardiosky #medsky #transplantsky
The second study in #ISHLTJournalWatch for February comes from @jimmunol.bsky.social and is presented by Nicole Chrysler, HBSc.
The paper explores the immunologic effects of pre-transplant IL-2 complex therapy in murine models.
#transplantsky #medsky #cardiosky
The February #ISHLTJournalWatch highlights topics in cardiothoracic transplant research and immunology, edited by Rupa Kanchi.🔬
The issue features Lauren East, Nicole Chrysler, Alexandra Mihai, and Baharan Zarrabian.
#ISHLT #MedSky #transplantsky
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#ISHLT #ISHLTEarlyCareer
The January #ISHLTJournalWatch focuses on topics in #transplant #pharmacy, edited by Colleen Hutchinson. 💊
Topics include the NUDT16 genotype, #daratumumab monotherapy, & early mammalian target of rapamycin inhibitor (#mTORi).
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#TransplantSky #PharmSky
The fourth slide of December 2025's ISHLT Journal Watch, reviewing the study "CD26/DPP-IV inhibitors and associations with chronic lung allograft dysfunction in a multicenter cohort." A more screenreader friendly version of the issue can be found at https://www.ishlt.org/docs/default-source/journal-watch/202512_journalwatch_pulm_dec2025.pdf
December's #ISHLTJournalWatch closes with Zsofia Rosselli's review of a manuscript from @jhlt.bsky.social on whether gliptins can moderate #CLAD. This multicenter cohort implies association, but requires further study.
#pulmsky #ISHLT #medsky #pharmsky
The third slide of December 2025's ISHLT Journal Watch, reviewing the study "Outcomes of Lung Transplantation for end stage lung disease with connective tissue disease: a systematic review and meta-analysis." A more screenreader friendly version of the issue can be found at https://www.ishlt.org/docs/default-source/journal-watch/202512_journalwatch_pulm_dec2025.pdf
Continuing #pulmsky studies in December's #ISHLTJournalWatch, Muhammad Hayat-Syed of @bcmhouston.bsky.social highlights a study on the distinctions between short- and long-term outcomes for #lungtxp patients with connective tissue disease.
#transplantsky #surgerysky
The second slide of December 2025's ISHLT Journal Watch, reviewing the study "Cell-free DNA in Ex-Vivo Lung Perfusate is Associated With Low-Quality Lungs and Lung Transplant Outcome." A more screenreader friendly version of the issue can be found at https://www.ishlt.org/docs/default-source/journal-watch/202512_journalwatch_pulm_dec2025.pdf
Next in #ISHLTJournalWatch, Alex Dragnich reviews a study from @jhlt.bsky.social—can #cellfreeDNA in #EVLP perfusate reflect #lung quality and affect the decision to use in #transplantation?
@sirusjj.bsky.social
The December #ISHLTJournalWatch highlights pulmonology research, edited by @sirusjj.bsky.social.
Topics include gliptins and #CLAD, #cfDNA in #EVLP perfusate, lung allocation strategy, and #connectivetissue diseases in #lungtx.
#ISHLT #pulmsky #transplantsky
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The third slide from the November 2025 issue of Journal Watch, titled "Maribavir for refractory cytomegalovirus (CMV) infection (with or without resistance) in solid organ transplant recipients: Subgroup analysis of the phase 3 randomized SOLSTICE study" For a more screenreader friendly version, the full issue PDF is at https://www.ishlt.org/docs/default-source/journal-watch/202511_journalwatch_id_nov2025.pdf.
Closing out November's #ISHLTJournalWatch, @sarawinndong.febrilepodcast.com reviews a study from @jhlt.bsky.social on the use of #Maribavir for #CMV infection in SOT recipients—an important addition to the toolbox in treating this infection in #transplant recipients.
#TransplantSky #IDSky #MedSky
The second slide from the November 2025 issue of Journal Watch, titled "Tolerability and clinical efficacy of letermovir for primary cytomegalovirus prophylaxis after heart transplantation" For a more screenreader friendly version, the full issue PDF is at https://www.ishlt.org/docs/default-source/journal-watch/202511_journalwatch_id_nov2025.pdf.
On #ISHLTJournalWatch this month, Brennan Collis reviews a paper from @jhlt.bsky.social on the clinical efficacy and tolerability of #letermovir for #CMV prophylaxis after #HeartTx.
#CardioSky #TransplantSky #IDsky #MedSky
The first slide from the November 2025 issue of Journal Watch, titled "Epidemiology and impact of device-specific infections on patients receiving left ventricular assist devices" For a more screenreader friendly version, the full issue PDF is at https://www.ishlt.org/docs/default-source/journal-watch/202511_journalwatch_id_nov2025.pdf.
In #ISHLTJournalWatch this month, @haithamalaithan.bsky.social reviews a paper from #JHLTOpen led by Amit Iyengar exploring the epidemiology and impact of device-specific infections on patients with #LVADs.
#medsky #cardiosky #ISHLT
November's #ISHLTJournalWatch highlights topics in #InfectiousDisease in heart/lung failure.
Led by @binni-id.bsky.social, the issue features @haithamalaithan.bsky.social, Brennan Collis, and @sarawinndong.febrilepodcast.com.
#IDSky #TransplantSky #MedSky
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This month on #ISHLTJournalWatch will be interesting to #pathsky and #transplantsky alike: the latest topics in #transplant #pathology, gathered and reviewed by #ISHLT early career members.
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The fourth slide from the September 2025 issue of Journal Watch, titled "Pig-to-human lung xenotransplantation into a brain-dead recipient." For a more screenreader friendly version, the full issue PDF is at https://www.ishlt.org/docs/default-source/journal-watch/2025-09-journalwatch-ctsurgery.pdf.
In the final study from last month's #CTSurgery #ISHLTJournalWatch, Anna Niroomand reviews the latest literature in @naturemedicine.bsky.social on pig-to-human #xenotransplantation of the #lung. 🫁
#LungTx #ISHLT #TransplantSky #PulmSky
In last month's #ISHLTJournalWatch, #KatharinaFetten reviews a study on the association of agonal phase duration with heart utilization & post-transplant outcomes in #DCD #HeartTransplantation. 🫀
#ISHLT #CardiogenicShock #TransplantSky
In the second study for #ISHLTJournalWatch last month, #RamDuvuru reviews a 5-year study on the outcomes of #DCD #HeartTransplantation. 🫀
#ISHLT #CardiogenicShock #TransplantSky
Headshots of the five early career professionals involved in the September Issue of ISHLT Journal Watch: Ram Duvuru, Katharina Fetten, Kevin Koomalsingh, Daniel Laskey, and Anna Niroomand. Text: ISHLT Journal Watch September 2025 Cardiothoracic Surgery Current papers, reviewed and presented by Early Career professionals.
This month on #ISHLTJournalWatch, issue editor Kevin Koomalsingh collects reviews of recent #CardiothoracicSurgery research from #ISHLTEarlyCareer professionals. Topics include #LungTxp in patients w/lesions, #DCD #HeartTxp, and #Xenotransplantation.
#PulmSky #CardioSky #SurgerySky #TransplantSky
The last slide from the August 2025 issue of Journal Watch, titled "Daratumumab monotherapy as a desensitization strategy prior to cardiac transplantation." For a more screenreader friendly version, the full issue PDF is at https://www.ishlt.org/docs/default-source/journal-watch/2025-08-journalwatch-cardiology.pdf.
The final study of last month's #ISHLTJournalWatch in #cardiology is from @jhlt.bsky.social.
#HasanSiddiqi reviews a study exploring #Daratumumab monotherapy as a #desensitization strategy prior to #HeartTx.
#cardiosky #transplantsky
The third slide from the August 2025 issue of Journal Watch, titled "Mavacamten in Patients With Hypertrophic Cardiomyopathy Referred for Septal Reduction: Week 128 Results From VALOR-HCM." For a more screenreader friendly version, the full issue PDF is at https://www.ishlt.org/docs/default-source/journal-watch/2025-08-journalwatch-cardiology.pdf.
In last month's #ISHLTJournalWatch, #BhanuRamachandran reviews a study led by Milind Y. Desai on the use of #Mavacamten in patients with obstructive hypertrophic #cardiomyopathy ( #oHCM ). Can Mavacamten allow clinicians to defer or avoid SRT use in these patients?
#ISHLT #CardioSky #TransplantSky
The second slide from the August 2025 issue of Journal Watch, titled "Early Intra-Aortic Balloon Support for Heart Failure-Related Cardiogenic Shock: A Randomized Clinical Trial." For a more screenreader friendly version, the full issue PDF is at https://www.ishlt.org/docs/default-source/journal-watch/2025-08-journalwatch-cardiology.pdf.
In the second study for #ISHLTJournalWatch last month, Max Berrill reviews a randomized #clinicaltrial from JACC about early #IABP for #HF-related #CardiogenicShock.
#CardioSky #TransplantSky
The fourth slide from the July 2025 issue of Journal Watch, titled "EDITORIAL SPOTLIGHT: Pediatric heart transplantation in donation after circulatory death: is it a feasible reality?--in time, yes!" For a more screenreader friendly version, the full issue PDF is at https://www.ishlt.org/docs/default-source/journal-watch/2025-07-journalwatch-pediatrics.pdf
Before Aug's #ISHLTJournalWatch comes out next week, finish reading the July #pediatrictransplant issue! The final slide of the issue spotlights an editorial on #pediatric #DCD.
When will it be a feasible reality?
How can centers expand access to #HeartTx?
What guidelines should pediatricians read?
The third slide from the July 2025 issue of Journal Watch, titled "Pediatric heart transplantation within the Scandiatransplant region--a multinational observational study spanning 38 years." For a more screenreader friendly version, the full issue PDF is at https://www.ishlt.org/docs/default-source/journal-watch/2025-07-journalwatch-pediatrics.pdf
Up next on #ISHLTJournalWatch: Multinational observations on #pediatric #HeartTx over a 38 year span in Nordic countries. In this time frame, transplant volume increased, waitlist mortality reduced, and #MCS use increased.
#ISHLT #CardioSky #TransplantSky
The first slide from the July 2025 issue of Journal Watch, titled "Contemporary outcomes of mechanical circulatory support using paracorporeal continuous flow pump in children: A report from the ACTION learning network." For a more screenreader friendly version, the full issue PDF is at https://www.ishlt.org/docs/default-source/journal-watch/2025-07-journalwatch-pediatrics.pdf
The 2nd study for July #ISHLTJournalWatch is an ACTION study assessing clinical outcomes in #pediatric patients supported on #paracorporeal continuous flow (pCF) pumps. 78% of children on pCF VADs had positive outcomes, but patients with #CHD had worse outcomes.
#ISHLT #MCS #VADs #pediatricHF