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UCSC Genome Browser: News Archives

🚀 New resource for epigenomics!

UCSC Genome Browser released the Human Methylation Atlas tracks (hg38 & hg19).

🔬 Genome-wide DNA methylation
🧬 39 cell types
🧑‍🔬 205 healthy samples

👉 genome.ucsc.edu/goldenPath/n...

#Genomics #Epigenomics #DNAme #UCS @genomebrowser.bsky.social

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Integrated transcriptomic and methylome analysis reveals retinoic acid pathway activation after decitabine treatment in EBV-associated gastric cancer | mBio EBV+ gastric cancer contains hypermethylated DNA, and despite this distinct molecular phenotype, there are currently no Epstein–Barr virus (EBV)-specific treatments available. Using an FDA-approved in...

Excited to share our new study: Integrated transcriptomic and methylome analysis reveals retinoic acid pathway activation after decitabine treatment in EBV-associated gastric cancer | mBio #EBV #Epigenetics #CancerResearch #GastricCancer #DNAme #Transcriptomics
journals.asm.org/doi/10.1128/...

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Explore how Novogene's WGBS revealed the catalytic impact of Dnmt3b on DNA methylation patterns across the genome. Dive into methylation landscapes, allele specificity & functional insights. #Epigenetics #DNAme #WGBS https://bit.ly/3ZAaQ3C

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New Epigenome Technologies Blog post! bit.ly/45aibKP

" Single-Cell Multi-Regional Atlas of DNA Methylation and 3D Chromatin Conformation in the AD-Affected Brain"

Based on a preprint from Bradley T. Hyman and Joseph R. Ecker

#Epigenetics #Chromatin #DNAme #ChromatinConformation #AD

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Epigenetics Update - Germline epigenome editing identifies H3K9me3 as a mediator of intergenerational DNA methylation recovery in mice go.nature.com/4sd4NQ1

Takuro Horii and Izuho Hatada in Nat Commun

#Epigenetics #H3K9me3 #DNAme #IEI
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Discover the breakthrough at epigenometech.com

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#Epigenetics #DNAme #GeneEnvironmentInteractions #PrenatalExposome #Epigenomics #Exposome

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Epigenetics Update - Roles of transposable elements and DNA methylation in the formation of CpG islands and CpG-depleted regulatory elements bit.ly/4ocNpsi

#Epigenetics #DNAm #DNAme #CpGIslands
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Empower your research with high-res epigenetic insights at epigenometech.com

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Epigenetics Update - Cell-type-specific DNA methylation dynamics in the prenatal and postnatal human cortex bit.ly/4gH3vYd

Alice Franklin/Jonathan Mill (University of Exeter) reporting in Cell Genomics

#Epigenetics #DNAme #DNAm
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Perfect for cancer, immunology, and aging; epigenometech.com

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Epigenetics Update - Systems Age: a single blood methylation test to quantify aging heterogeneity across 11 physiological systems go.nature.com/42qOLqf

#Epigenetics #Aging #DNAme #DNAm #EpigeneticAging
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Perfect for cancer, immunology, and aging research; epigenometech.com

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Epigenetics Update - Gene body methylation regulates gene expression and mediates phenotypic diversity in natural Arabidopsis populations go.nature.com/46jktqU

Zaigham Shahzad/Daniel Zilberman (John Innes Centre)

#Epigenetics #Chromatin #DNAme
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Discover the breakthrough at epigenometech.com

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Epigenetics Review - Non-CG DNA methylation in animal genomes go.nature.com/41NGOLH

Alex de Mendoza and Ozren Bogdanovic reporting in Nat Genet

#Epigenetics #DNAme #DNAm #Reviews
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Empower your research with high-res epigenetic insights at epigenometech.com

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Epigenetics Update - DNA methylation cooperates with genomic alterations during non-small cell lung cancer evolution go.nature.com/4m7ipYV

Peter Van Loo and Nnennaya Kanu reporting in Nat Genet

#Epigenetics #DNAme #DNAm #Cancer
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Discover the breakthrough at epigenometech.com

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Epigenetics Update - Fluctuating DNA methylation tracks cancer evolution at clinical scale go.nature.com/3Ve4OUy

#Epigenetics #Cancer #DNAme #DNAm
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Empower your research with high-res epigenetic insights at epigenometech.com

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Epigenetics Update - DNA methylation influences human centromere positioning and function go.nature.com/4mGYiSi

Nicolas Altemose (Stanford) and Daniele Fachinetti (Sorbonne Université) reporting in Nat Genet

#Epigenetics #DNAme #DNAm #DNAmethylation
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High-resolution insights; epigenometech.com

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Epigenetics Update - Spatial joint profiling of DNA methylome and transcriptome in tissues go.nature.com/4p0bbs9

#Epigenetics #DNAme #DNAm #SpatialProfiling
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Perfect for cancer, immunology, and aging research; epigenometech.com

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Epigenetics Update - Preventing CpG hypermethylation in oocytes safeguards mouse development bit.ly/41u5adm

Antoine H.F.M. Peters (FMI/ University of Basel) reporting in Dev Cell

#Epigenetics #DNAme #DNAm #DNAdemethylation #Embryogenesis
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Discover the breakthrough at epigenometech.com

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Check out our new blog on how single-cell epigenetic and transcriptomic analyses describe brain aging in mice in detail!

"Single-Cell Transcriptomic and Epigenetic Profiling Highlights the Mechanisms Underlying Brain Aging" bit.ly/47ARNM4

#Epigenetics #Aging #SingleCell #DNAme #DNAm #Blog

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How ageing changes our genes — huge epigenetic atlas gives clearest picture yet A map of DNA methylation changes in human organs could help researchers to discover more targets for anti-ageing therapies.

Epigenetics News - How ageing changes our genes — huge epigenetic atlas gives clearest picture yet go.nature.com/4mIDkCJ

A map of DNA methylation changes in organs may help to reveal targets for anti-ageing therapies

#Epigenetics #DNAme #DNAm #Aging
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Gain deeper insights with epigenometech.com

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Epigenetics Update - Single-cell DNA methylome and 3D genome atlas of human subcutaneous adipose tissue go.nature.com/41i2boa

Päivi Pajukanta (UCLA) reporting in Nat Genet

#Epigenetics #DNAme #DNAm #Adipose #TissueAtlas
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Empower your research at epigenometech.com

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Webinars now on-demand!

🧬 DNA Methylation: Cost vs. Coverage
🔬 CUT&RUN Optimization Tips

Watch the replays:
▶ app.livestorm.co/epicypher/dn...
▶ app.livestorm.co/epicypher/un...

#Epigenetics #ChromatinMapping #CUTandRUN #DNAme

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Epigenetics Update - UHRF2 mediates resistance to DNA methylation reprogramming in primordial germ cells go.nature.com/459p0g8

Michael Weber (Université de Strasbourg) in Nat Commun

#Epigenetics #DNAme #DNAm #PGCs
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Perfect for cancer, immunology, and aging research; epigenometech.com

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New Blog Incoming!

Simultaneous DNA Methylation and Chromatin Conformation Analysis Describes Brain Aging at the Single Cell Level bit.ly/3TQkmxb

Discover how multimodal epigenetic analysis provides an improved understanding of brain aging

#Epigenetics #DNAme #DNAm #SingleCell #Multiomics #Aging

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Plants repress ROS1 expression to attenuate heat-induced transposon burst - Nature Plants Plants suppress the DNA demethylase ROS1 under heat stress to limit transposon activation, preventing genome instability. This conserved mechanism balances stress adaptation with genome protection.

Epigenetics Update - Plants repress ROS1 expression to attenuate heat-induced transposon burst go.nature.com/4fxjBmr

Weiqiang Qian (Peking University) reporting in Nat Plants

#Epigenetics #Plants #DNAme #DNAm
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Gain deeper insights into gene regulation; epigenometech.com

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Circulating epigenetic signatures classifying brain insulin resistance in humans Blood-based epigenetic signatures distinguish between individuals with and without brain insulin resistance across multiple cohorts.

Epigenetics Update - Circulating epigenetic signatures classifying brain insulin resistance in humans bit.ly/3UedWbp

Meriem Ouni and Annette Schürmann in Sci Trans Med

#Epigenetics #DNAme #DNAm #BrainInsulinResistance
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Perfect for cancer, immunology, and aging research; epigenometech.com

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Exploring Chromatin Conformation bit.ly/3IhaFVT

Read Part 3 of our review of an exciting new pre-print article

#Epigenetics #Multiomics #SingleCell #DNAme #ChromatinConformation

epigenometech.com

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Epigenetics Update - Mechanisms and reversibility of nicotine-induced spermatogenesis impairment and DNA methylation changes go.nature.com/44wDI0n

Jing Shu and Guolian Ding reporting in Commun Biol

#Epigenetics #DNAme #DNAm
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High-resolution insights without cell sorting; epigenometech.com

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Analyzing DNA Methylation Variability Across Cell Types bit.ly/4lwTKNj

Read Part 2 of our review of an exciting new pre-print article

#Epigenetics #Multiomics #SingleCell #DNAme #ChromatinConformation

epigenometech.com

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Epigenetics Update - DNA hypomethylation traits define human regulatory T cells in cutaneous tissue and identify their blood recirculating counterparts go.nature.com/3Ix7Xf1

#Epigenetics #DNAme #DNAm #Immunology
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Empower your research with high-res epigenetic insights at epigenometech.com

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Huge thanks to the organizers for the invitation and to all the brilliant minds shaping the future of longevity and translational health 🧬🙌

#LongevityTech #SystemsBiology #DNAme #Healthspan

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Epigenetics Update - MethAgingDB: a comprehensive DNA methylation database for aging biology go.nature.com/4ltmg2T

Haixin Wang and Shengquan Chen reporting in Scientific Data

#Epigenetics #DNAm #DNAme #Aging
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Empower your research with high-res epigenetic insights at epigenometech.com

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