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DNA Methylation in Ecology and Evolution 20th-24th April 2026 To foster international participation, this course will be held online

Only a few spots are still available for our online #DNAMethylation course with @alexdemendoza.bsky.social hollie & James in April. Join us to learn cutting-edge methods for analyzing methylation data from Illumina, @nanoporetech.com & @pacbio.bsky.social

www.physalia-courses.org/courses-work...

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Hello World ! Today, we have been so lucky to host the one and only Emily Hodges @hodges-lab.bsky.social to hear about her research. So many idea, so much cool stuff. Thank you Emily for sharing your science with us @igred.fr !
#Friends #Science #DNAmethylation #watwat

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The mirage of DNA methylation in transcriptional regulation of plants Links between DNA methylation and transcription remain difficult to generalize and are weak on genome-wide scales. Multiple lines of evidence suggest DNA methylation plays only a minor role in the r...

🧬Does DNA methylation really control gene expression in plants?
Our new paper challenges this assumption — showing that methylation and transcription often avoid one another rather than align. Why is that?
acsess.onlinelibrary.wiley.com/doi/10.1002/...
#Epigenetics #DNAmethylation #GeneRegulation

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Antonysunil Adaikalakoteswari presented at #SFEBES2026 on how maternal vitamin #B12 deficiency affects #placental development. Using #multiomics data from the #PRiDE cohort, the study found changes in #DNAmethylation, gene expression and #miRNAs linked to low B12.
@socendocrinology.bsky.social

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The wucai genome and DNA methylation regulation on the inner leaves’ yellowing response to low temperature Abstract. Wucai (Brassica rapa), a widely cultivated non-heading Chinese cabbage in autumn and winter in China, has been limited in its genetic and genomic

High-quality wucai genome (480.57 Mb) reveals CHH methylation's role in low-temp yellowing, aiding breeding. #WucaiGenome #DNAMethylation #ChlorophyllMetabolism @academic.oup.com
Details: doi.org/10.1093/hr/u...

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#DNAmethylation data provides an exciting avenue for studying wildlife health. This paper reviews methods used to study methylation, and discusses the potential applications in wildlife, using bottlenose dolphins 🐬 as a case study.

Read it here ➡️ doi.org/10.1093/conp... #Epigenetics #Conservation

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It highlights the fascinating intertwined nature of developmental and ageing-related pathways.
Thanks to #impetusgrants #hevolution [2/2]
#CpG #ucCpGs #epigenomics #DNAmethylation #ageing #aging #populationgenetics @qmulepigenetics.bsky.social sky.social
doi.org/10.64898/202...

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📝Now online - the Review "5mC and 6mA DNA methylation in eukaryotic genomes" from Bei Nan and Shan Gao.

#DNAmethylation #TranscriptionRegulation #Evolution

Read it free (until April 10) here: authors.elsevier.com/a/1mePJ3S6Gf...

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Chocolate Compound Linked to Slower Biological Aging - Aging-US Research While chocolate and coffee have been associated with better health outcomes, pinpointing the responsible  specific compounds has been difficult. These foods contain multiple bioactive substances that ...

✅ Read our #blog post about the #research paper, titled "Theobromine is associated with slower epigenetic ageing."

#Summary ⬇️
aging-us.org/2026/01/choc...

#aging #TrendingWithImpact #chocolate #theobromine #nutrition #DNAMethylation #oa #peerreviewed #journal #publishing #meded

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So proud of these amazing young scientists and all their hard work! Congratulations, ladies, thank you for being part of this group and for representing our lab🧬 🔬 🧫. #uiowadentistry #cleftlipandpalate #vanderwoude #cleftresearch #epigenetics #dnamethylation #aadocr #womeninscience
#proudmentor

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Ready for the 73rd Iowa Section of the AADOCR. Come see our work on Genomics and Epigenomics of Orofacial Clefts and Van der Woude Syndrome. #uiowadentistry #uiowaresearch #cleftlipandpalate #vanderwoude #cleftresearch #epigenetics #dnamethylation #aadocr #womeninscience

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Epigenetic regulation of ACE2 & TMPRSS2 expression is influenced by histone acetylation & #DNAmethylation, with HDAC inhibition shown to increase their expression & enhance viral replication

www.ijbs.com/v18p4731.htm

www.frontiersin.org/journals/cel...

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DNA Methylation in Ecology and Evolution 20th-24th April 2026 To foster international participation, this course will be held online

Curious how #DNAMethylation shapes ecology and evolution? 🧬 Join our online course (20–24 Apr) with @alexdemendoza.bsky.social Hollie Marshall & James Ord and get hands-on with Illumina, @nanoporetech.com & @pacbio.bsky.social data! 🚀

www.physalia-courses.org/courses-work...

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Reading DNA methylation for Cancer Diagnosis Why DNA Methylation Matters – When we think about DNA, we often think of it as a static genomic sequence. But in reality, additional regulatory layers, known as epigenetic mechanisms, play a …

🛋️💡Learn more about the usage of #DNAmethylation for #CancerDiagnosis and the study by Daria and her co-authors in our new blog article! 🧬 🔎
🔗 www.rna.uni-jena.de/reading-dna-...

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Chocolate Compound Linked to Slower Biological Aging - Aging-US Research While chocolate and coffee have been associated with better health outcomes, pinpointing the responsible  specific compounds has been difficult. These foods contain multiple bioactive substances that ...

✅ Read our #blog post about the #research paper, titled "Theobromine is associated with slower epigenetic ageing."

#Summary ⬇️
aging-us.org/2026/01/choc...

#aging #TrendingWithImpact #chocolate #theobromine #nutrition #DNAMethylation #oa #peerreviewed #journal #publishing #meded

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The DMR signature demonstrated robust applicability in predicting tumor progression. (A) Principal component analysis of 14-DMR signature patients under 120 samples with tumor progression (deep grey) or not (light grey). Circle color referred to the risk group. Tumor progression (B) and tumor recurrence (C) ROC curve of prognostic prediction using 14-DMR signature (blue), GS (purple), and tumor T stage (green). The AUC value of each curve and the statistical significance (*0.05, **0.01, ***0.001) of differences compared to the signature were summarized in the lower right corner of the plots.

The DMR signature demonstrated robust applicability in predicting tumor progression. (A) Principal component analysis of 14-DMR signature patients under 120 samples with tumor progression (deep grey) or not (light grey). Circle color referred to the risk group. Tumor progression (B) and tumor recurrence (C) ROC curve of prognostic prediction using 14-DMR signature (blue), GS (purple), and tumor T stage (green). The AUC value of each curve and the statistical significance (*0.05, **0.01, ***0.001) of differences compared to the signature were summarized in the lower right corner of the plots.

Muheng Liao & co show that a DNA methylation signature outperformed traditional clinical markers in predicting prostate #cancer progression, offering improved risk assessment for treatment decisions in intermediate-risk patients. doi.org/10.1242/bio....

#ProstateCancer #DNAmethylation

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Skeletal Muscle Epigenetic Clocks Developed Using Postmortem Tissue from an Asian Population | Aging This study introduces the skeletal muscle epigenetic clocks in an Asian population using postmortem skeletal muscle tissue."Click here to listen to the press releaseBUFFALO, NY — December 30, 202...

🔆 #PaperSpotlight:
This #research paper was #published in Volume 17, Issue 11, titled "Epigenetic aging signatures and age prediction in human skeletal muscle."

#PressRelease ⬇️
www.aging-us.com/news-room/sk...

#aging #DNAMethylation #NGS #press #epigenetics #oa #journal #publishing

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🔆 #PaperSpotlight:
A new #research paper was #published on November 26, titled “Epigenetic aging signatures and age prediction in human skeletal muscle.”

🔗 doi.org/10.18632/agi...

#aging #quote #DNAMethylation #NGS #epigenetics #muscle #openaccess #peerreviewed #journal #publishing

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🎥 #AgingShort:
Abstract #video about the #research paper “Epigenetic aging signatures and age prediction in human skeletal muscle.”

🔗 doi.org/10.18632/agi...

#aging #PaperSpotlight #DNAMethylation #NGS #muscle #epigenetics #oa #peerreviewed #journal #publishing #meded

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Down-regulation of RBM47 due to diminished activation by forkhead box A1 (FOXA1) and silencing by CpG methylation is associated with epithelial-mesenchymal transition and metastasis of colorectal canc... The gene encoding the RNA-binding motif protein 47 (RBM47) is highly expressed in epithelial cells and its down-regulation is characteristic for many types of cancer, among them colorectal cancer (CRC...

#Research
Down-regulation of #RBM47 due to diminished activation by forkhead box A1 ( #FOXA1) and silencing by #CpG methylation is associated with epithelial-mesenchymal transition ( #EMT) and #metastasis of #ColorectalCancer
doi.org/10.1186/s435...

#DNAmethylation

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Transcription factors instruct DNA methylation patterns in plant reproductive tissues - Nature Cell Biology Xu et al. identify REPRODUCTIVE MERISTEM transcription factors that are required for RNA-directed DNA methylation at CLASSY3 target loci in male and female reproductive tissues of Arabidopsis.

☕Xu et al. identify REPRODUCTIVE MERISTEM #TranscriptionFactors that are required for RNA-directed #DNAmethylation at CLASSY3 target loci in male and female reproductive tissues of Arabidopsis.
bit.ly/4iYqr6d

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Theobromine From Cocoa Linked to Slower Biological Aging BUFFALO, NY — December 16, 2025 — A new #research paper was #published in Aging-US on December 10, 2025, titled “Theobromine is associated with slower epigenetic ageing.” In this study, led by Ramy S

🎧 Listen to our #pressrelease about the #research paper, titled "Theobromine is associated with slower epigenetic ageing."

soundcloud.com/aging-us/the...

#aging #PaperSpotlight #podcast #audio #SoundCloud #press #theobromine #nutrition #DNAMethylation #epigenetics #oa #publishing

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Theobromine From Cocoa Linked to Slower Biological Aging | Aging Our findings indicate that the reported beneficial links between theobromine intake on health and ageing extend to the molecular epigenetic level in humans."Click here to listen to the press rele...

🔆 #PaperSpotlight:
This #research paper was #published on December 10, 2025, titled "Theobromine is associated with slower epigenetic ageing."

#PressRelease ⬇️
www.aging-us.com/news-room/th...

#aging #press #theobromine #nutrition #DNAMethylation #epigenetics #oa #journal #publishing

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🎥 #AgingShort:
Abstract #video about this #research paper, titled “Theobromine is associated with slower epigenetic ageing.” @kingscollegelondon.bsky.social

🔗 doi.org/10.18632/agi...

#aging #PaperSpotlight #theobromine #nutrition #dnamethylation #epigenetics #openaccess #journal #publishing

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Spotlight: DNMTs in Epigenetics 🔗 bit.ly/3MwHlNj
DNMTs establish and maintain DNA methylation—controlling gene expression and directing cell differentiation.

➡️ Explore DNMTs on our Epigenetics on Target page: bit.ly/3MwHlNj
_____
#Epigenetics #DNMTs #DNAMethylation #ActiveMotif

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Epigenetic drugs in cancer therapy: mechanisms, immune modulation, and therapeutic applications - Molecular Biomedicine Epigenetic regulation is a fundamental mechanism controlling gene expression and cellular function, primarily mediated through reversible modifications such as DNA methylation, histone acetylation, an...

#Review
Epigenetic drugs in cancer therapy: mechanisms, immune modulation, and therapeutic applications doi.org/10.1186/s435...

#EpigeneticRegulation #DNAmethylation #HistoneModifications #TumorImmunity #ClinicalTranslation

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#DNAMethylation - Based #EpigeneticClocks & Their Role in Aging.
🔑 highlights
-DNA methylation-based epigenetic clocks are established tools for estimating biological age by measuring methylation at specific CpG sites with widely used models incl the Horvath clock, Hannum clock, PhenoAge & GrimAge

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DNA Methylation in Ecology and Evolution 20th-24th April 2026 To foster international participation, this course will be held online

Curious how #DNAmethylation shapes ecology & evolution? 🚀 Join our hands-on online course (Apr 20-24) with Hollie @alexdemendoza.bsky.social & James to master cutting-edge analysis with Illumina, #Pacbio & #Nanopore data.

www.physalia-courses.org/courses-work...

#Epigenetics #Bioinformatics

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ChIP Antibodies | Antibodies.com Choose the best ChIP antibodies for your research, including those against histones, histone modifications, transcription factors and mo re.


This year also brought impressive progress in the use of ChIP-based technologies in #LiquidBiopsies. Several notable papers described changes in #DNAmethylation as #BioMarkers for #cancer.

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Original post on mastodon.social

+++ Was ist das 🌱 #Endocannabinoidsystem des Menschen? +++

lerne mehr: ➡️ ➡️ ➡️ https://youtu.be/WXN9EuQsz8w [in Deutsch]

#Cannabinoids #epigenetics #DNAmethylation #addiction #CB1receptor #neurodevelopment #traumata #janov #Studie #Merz #Söder #Bas #Schwerdtner #Klingbeil #ThorstenFrei […]

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