Epigenetic Signatures in Monozygotic and Dizygotic Twins Discordant for Orofacial Clefts Introduction: Nonsyndromic cleft lip with or without cleft palate (NSCL/P) is a common congenital malformation with complex etiology involving both genetic and environmental factors. Epigenetic mechan...

🧬 New preprint alert! Excited to share our twin study on the epigenetics of orofacial clefting — available on #medRxiv. 🔬 🧪
www.medrxiv.org/content/10.6...
#cleftlipandpalate #twinstudies #uiowadentistry #womeninscience #uiowaresearch #nidcr #epigenetics #dnamethylation #EWAS

The Petrin Lab is heading to the #IADR2026 General Session next week — and we are buzzing with excitement to share our work! 🦷🧬
#IADR2026 #CraniofacialGenetics #OrofacialClefts #VanDerWoudeSyndrome #Zebrafish #Epigenetics #OAVS #DentalResearch #UIowaDentistry #uicod #womeninscience #uiowaresearch

Ready for the 73rd Iowa Section of the AADOCR. Come see our work on Genomics and Epigenomics of Orofacial Clefts and Van der Woude Syndrome. #uiowadentistry #uiowaresearch #cleftlipandpalate #vanderwoude #cleftresearch #epigenetics #dnamethylation #aadocr #womeninscience

Laterality and Completeness Patterns of Nonsyndromic Clefts in a Multiethnic Cohort Objective: Orofacial clefts may involve the complete vertical thickness of the lip (complete) or partial thickness (incomplete). This study evaluates side preference for completeness in nonsyndromic a...

Our latest research is now available on MedRxiv. We examined laterality and completeness patterns in nonsyndromic cleft lip with or without cleft palate (NSCL/P) across a multiethnic cohort. #uiowaresearch #laterality #cleftresearch #uiowadentistry

www.medrxiv.org/content/10.6...

CRISP grant supports study of genetic variation in Van der Woude syndrome Aline Petrin, assistant professor of orthodontics, received a CRISP grant to complete genetic screening of patients with Van der Woude syndrome. Her study will help clarify how genetic mutations influ...

Grateful for the continued support to our research program! 🙏 🧬 🔬 #uiowadentistry #uiowaresearch #cleftlipandpalate #epigenetics #uicod
#womeninscience #vanderwoude
University of Iowa College of Dentistry and Dental Clinics

dentistry.uiowa.edu/news/2025/09...

Kicking off two days of learning and scientific networking at the University of Minnesota. Come see poster 31 to learn more about our work on Methylation Quantitative Traits and Orofacial Clefts #uiowadentistry #uiowaresearch #cleftlipandpalate #epigenetics #uicod #womeninscience #scgdb2025

Another Hatton Award for Iowa! Congratulations, Saba Manafi for winning 2nd place Junior Category! It is so rewarding to see your hard work recognized. #proudmentor 🎉 ❤️ #IADR2025 #uiowadentistry #uiowaresearch #cleftlipandpalate #womeninscience #oavs #PetrinLab

Wrapping the #AADOCR2025 meeting in NYC. What an amazing week of learning, networking and reconnecting with friends! #uiowadentistry #uiowaresearch #cleftlipandpalate #uicod #proudmentor #craniofacial #twinstudies #oavs #aadocr2025 🧬 🦷 🔬 🗽

Another successful day for the Petrin Lab at #AADOCR2025. Great presentations by these bright young scientists. Thank you for your dedication representing our work!
#uiowadentistry #uiowaresearch #cleftlipandpalate #uicod #proudmentor #twinstudies #aadocr2025 🧬 🦷 🔬

#Proudmentor moment! Super congratulations to this amazing young scientist for all her hard work on this project and for winning second place in the #AADOCR2025 Hatton Competition! Next stop - Barcelona 🇪🇸 #IADR2025
#uiowadentistry #uiowaresearch #cleftlipandpalate #uicod #womeninscience #oavs

10 days until the #AADOCR2025 in New York City. Come visit our posters and hear from these amazing students about their work on genetic and epigenetics of orofacial clefts. #uiowadentistry #uiowaresearch #cleftlipandpalate #epigenetics #uicod #womeninscience #genetics #twinstudies #nidcr #aadocr2025

Methylation quantitative loci analysis in nonsyndromic orofacial clefts Objectives: Nonsyndromic orofacial clefts (OFCs) etiology involves multiple genetic and environmental factors with over 60 identified risk loci; however, they account for a minority of the estimated r...

New preprint from the Petrin Lab: doi.org/10.1101/2025...
We show that non-coding cleft-associated SNPs can affect cleft risk through DNA methylation (meQTLs). #uiowadentistry #uiowaresearch #cleftlipandpalate #epigenetics #womeninscience #twinstudies #nidcr #meqtl

DNA Methylation Effects on Van der Woude Syndrome Phenotypic Variability - Amanda Seaberg, Waheed Awotoye, Fang Qian, Ligiane A. Machado-Paula, Lindsey Dunlay, Azeez Butali, Jeff Murray, Lina Moreno-... Objective Van der Woude Syndrome (VWS) presents with combinations of lip pits (LP) and cleft lip and/or cleft palate (CL/P, CPO). VWS phenotypic heterogeneity e...

Check out our new paper on DNA Methylation Effects on Van der Woude Syndrome Phenotypic Variability. #uiowadentistry #uiowaresearch #cleftlipandpalate #epigenetics #vanderwoudesyndrome #lipits #uicod #womeninscience #proudmentor #nidcr #PetrinLab
doi.org/10.1177/1055...