Methylation quantitative loci analysis in nonsyndromic orofacial clefts Objectives: Nonsyndromic orofacial clefts (OFCs) etiology involves multiple genetic and environmental factors with over 60 identified risk loci; however, they account for a minority of the estimated r...

New preprint from the Petrin Lab: doi.org/10.1101/2025...
We show that non-coding cleft-associated SNPs can affect cleft risk through DNA methylation (meQTLs). #uiowadentistry #uiowaresearch #cleftlipandpalate #epigenetics #womeninscience #twinstudies #nidcr #meqtl