Epigenetic drugs in cancer therapy: mechanisms, immune modulation, and therapeutic applications - Molecular Biomedicine Epigenetic regulation is a fundamental mechanism controlling gene expression and cellular function, primarily mediated through reversible modifications such as DNA methylation, histone acetylation, an...

#Review
Epigenetic drugs in cancer therapy: mechanisms, immune modulation, and therapeutic applications doi.org/10.1186/s435...

#EpigeneticRegulation #DNAmethylation #HistoneModifications #TumorImmunity #ClinicalTranslation

This recent review examines CXorf67, emphasizing its dual role in #EpigeneticRegulation and #DNADamage response, promising it as a #therapeutic target for mechanistically informed strategies in #CancerResearch. #medsky

#OpenAccess: www.sciencedirect.com/science/arti...

Chidamide (a Histone Deacetylase Inhibitor) Plus Abiraterone in Metastatic Castration‐Resistant Prostate Cancer (mCRPC): A Phase Ib Trial Metastatic castration-resistant prostate cancer (mCRPC) remains challenging. This Phase Ib trial tested chidamide, a selective HDAC inhibitor, plus abiraterone in 18 patients. The regimen was well to...

#Article in #MedComm
Chidamide (a Histone Deacetylase Inhibitor) Plus Abiraterone in Metastatic Castration-Resistant Prostate Cancer (mCRPC): A Phase Ib Trial doi.org/10.1002/mco2...
#Clinicaltrial #EpigeneticRegulation #HistoneDeacetylase #mCRPC

Haplotype-resolved genome and multi-omics landscape reveal an epigenetic regulation of citric acid accumulation in lemon. #LemonGenome #HaplotypeResolvedGenome #EpigeneticRegulation @plantphys.bsky.social
academic.oup.com/plphys/advan...