Adjuvant immunotherapy for muscle-invasive urothelial carcinoma: Considerations for targeting patients

Bladder Cancer
@journals.sagepub.com

journals.sagepub.com/doi/10.1177/...

#urology #cancer #oncology #biomarker #ctDNA #immunotherapy #openaccess

Excited to exhibit at the @theaacr.bsky.social annual meeting this year! Stop by booth 3956 to see how Omics Playground streamlines omics data analysis for #oncology researchers, making complex datasets accessible across your team while accelerating #biomarker discovery🧬

Researchers identified that CCR7 exhibits dual roles in HCC, promoting tumor progression yet enhancing immune response in stromal contexts, offering a #Biomarker for precision therapy and improved #Immunotherapy outcomes. @fudan-university.bsky.social

#STTT #OpenAccess: doi.org/10.1038/s413...

New biomarker improves diagnosis of Parkinson's and LBD An international consortium has achieved a major breakthrough in the diagnosis of neurological diseases. In a recent publication, they describe the discovery of a new quantitative biomarker in lumbar ...

A #biomarker discovered in the cerebrospinal fluid by researchers from 🇳🇱 @amsterdamumc.bsky.social and @sebastiaan-e.bsky.social from 🇧🇪 Vrije Universiteit Brussel could improve diagnosis of #Parkinsons disease and #dementia with Lewy bodies.

#Biomarker validation is crucial, misuse can lead to false results and poor outcomes.
Learn more about biomarkers validation in our blog: www.fiosgenomics.com/biomarker-validation-avo...
#bioinformatics #drugdevelopment

Lymphome stiften Chaos im Lymphknoten Neue Forschung zeigt, warum die Architektur des Lymphknotens bei bösartigen Lymphomen schrittweise abgebaut wird

#Lymphdrüsenkrebs programmiert Immunzellen um und verändert damit #Lymphknoten tiefgreifend. Diese Erkenntnis von Forschern der @hhu.de und Uniklinik Düsseldorf, gemeinsam mit @dkfz.bsky.social, @embl.org, @bihatcharite.bsky.social und @unibas.ch, zeigt neue Perspektiven für #Biomarker und Therapien

#Exosomal lnc-TAF12–2:1 is upregulated in #BladderCancer, driving proliferation by sponging miR-7847–3p to stabilize ASB12; its inhibition suppresses #tumorigenesis, positioning it as a novel diagnostic and therapeutic #biomarker.

#OpenAccess: doi.org/10.1016/j.ge...

As Colorectal Cancer Rises in Younger Populations, Research and Education is More Important than Ever | Pfizer At one time, colorectal cancer was a disease associated with older adults. Now, it’s considered the most deadly cancer in people younger than 50.

#Pfizer has a new article discussing trends of Colorectal #Cancer in your population and treatment options including #Biomarker therapies and early warning signs. Read Below:

#biomarker #tutorial
bsky.app/profile/bffo...

Online tutorial on survival analysis for biomarker discovery Author summary In teaching data science, one of the biggest challenges is engaging the audience. Hands-on learning is a powerful way to do this—after all, the field itself starts with data. Another ke...

From @plos.org #Computational #Biology | Online tutorial on survival analysis for biomarker discovery | #Bioinformatics #Education #OpenScience #OpenEducationalResources #Tutorial #Biomarker #Kaplan-Meier | 🧬 🖥️ 🧪 🔓
⬇️
journals.plos.org/ploscompbiol...

This year, over 154k people will be diagnosed with colon cancer in the U.S. 53k will die.
Colon cancer is The PREVENTABLE CANCER. Getting screened SAVES lives.
Learn your choices leadfrombehind.org
#fightCRC #PrioritizeCRC #biomarker #enoughCRC
#screenat45 #TomorrowCantWait

3/ IFN-γ as LC biomarker (Cambridge): Persists up to 31mo. >60% saw symptoms resolve with IFN-γ decline. Vaccination helped some. Supports interferon subtyping of LC.

#LongCovid #biomarker

Colorectal cancer is the second deadliest cancer in America. Project Cure CRC is here to change that. This national initiative is accelerating research, funding studies, and bringing new hope to patients and families.
#fightCRC #PrioritizeCRC #biomarker #nationalcolorectalcancerawarenessmonth

Biomarker testing can improve cancer treatment outcomes, but many Americans do not have equal access, even through insurance. Join me and advocate for access. To learn how, download these instructions from the Colorectal Cancer Alliance: bit.ly/biomarker-ad...
#fightCRC #PrioritizeCRC #biomarker

Schizophrenia study finds new biomarker, drug candidate to treat cognitive symptoms Large study was in human cerebral spinal fluid and mouse models

#Schizophrenia study reveals a new #biomarker for diagnosing the disorder; a form of the #brain protein called #Cacna2d1 is reduced in patients with the condition, which results in overstimulated neural circuitry.
news.northwestern.edu/stories/2026...

🔜 #ELCC26 @myesmo.bsky.social
🔥Unlocking the future: Bispecific immunotherapy and novel combinations in lung cancer
☑️ #ADC #SCLC #Toxicity #Biomarker
🎙️Chair: Dr. Jhanelle Gray, Dr. Benjamin Besse
@oncoalert.bsky.social LARVOL #LCSM

🧬 Metabolomics is unlocking new possibilities in personalised medicine!

In MICROB-PREDICT, researchers showed that urine & stool can reveal even more #biomarker insights than blood🩸, helping predict outcomes in severe #LiverDisease earlier.

Christophe Junot (CEA) on YouTube:
📽️ youtu.be/TYObOSu_r2w

Spironolactone and Fibrosis in Heart Failure Risk: Machine Learning Analysis of HOMAGE Trial Plasma Proteomics In HOMAGE, 276 plasma proteins were profiled using Olink panels. Machine learning algorithms identified galectin-9 (GAL9), thrombospondin-2 (THBS2), and NT-proBNP as predictors of changes in procolla....

#Article in @medcomm.bsky.social #MedComm
#Spironolactone and #Fibrosis in Heart Failure Risk: #MachineLearning Analysis of #HOMAGE Trial Plasma Proteomics doi.org/10.1002/mco2...

Researchers from CIMA Universidadde Navarra and IdiSNA, Spain

#biomarker #HeartFailure #MLA #PICP

🔜 #ELCC26 @myesmo.bsky.social
🔥Perioperative treatments for early lung cancer
☑️ #AGA #Adjuvant #Neoadjuvant #Perioperative #Biomarker
🎙️Chair: Dr. Enriqueta Felip, Dr. James Spicer
@oncoalert.bsky.social LARVOL #LCSM

🔜 #ELCC26 @myesmo.bsky.social
🔥Adaptive escalation and de-escalation treatment for NSCLC
☑️ #Biomarker #DeEscalation #Escalation #TrialDesign
🎙️Chair: Dr. Stephanie Saw Dr. Jordi Remon
@oncoalert.bsky.social LARVOL #LCSM

"Discovery of Donor-Derived Exosomal DNA as an Exploratory Biomarker of Kidney Graft Rejection: A Cross-Sectional Study"

Read more here: shorturl.at/rUhNA

#exosomal #DNA #biomarker #kidney #graft #rejection @esottransplant.bsky.social @hospitalclinic.bsky.social

#GPNMB is a key #biomarker of #metabolic disorders — but what is its role in adaptation to #obesogenic diets? With help from a FoxBox #Respirometry System, scientists showed that GPNMB inactivation disrupts diurnal #hepatic glycogen #metabolism.

buff.ly/OcRp6jb

#Obesity

Biovica Q3 Earnings call #biovicb #investors #biomarker #pharma

REMINDER!
Register for our upcoming Q3 Earnings call taking place:
Wednesday 18th March, 2025 at 15:00 CET.

Register here: http://bit.ly/4rqjH3I

Presenters are:
Anders Rylander, CEO
Anders Morén, CFO

#biovicb #investors #biomarker #pharma

🚀From Bench to Paper | New work in EClinicalMedicine: a circulating three-lipid signature (3LS)—previously identified as a poor prognostic #biomarker in metastatic castration-resistant #ProstateCancer (#mCRPC), actively contributes to disease progression.
#LipidMetabolism #CancerResearch

Want to boost the success of your preclinical development plan?
From target identification to #biomarker discovery, find out how bioinformatics can help at each stage of the #preclinical development:
www.fiosgenomics.com/optimise-your-preclinica...

Metastasierender Prostatakrebs: Neuer Blutmarker eröffnet neue Perspektiven Forschungsteam am OncoRay identifiziert MMP11 als vielversprechenden Biomarker für die Flüssigbiopsie

Forscher vom #OncoRay – Nationales Zentrum für Strahlenforschung in der Onkologie haben einen im 🩸 Blut messbaren #Biomarker identifiziert, mit dem sich aggressive Tumorverläufe und der Therapieerfolg bei metastasierendem #Prostatakrebs frühzeitig vorhersagen lassen, berichtet @hzdr.bsky.social.

Metabolic marker profiling of circulating tumour cells in NSCLC patients treated with osimertinib: focus on MCT1 and MCT4
@tamedoncol.bsky.social
@journals.sagepub.com

journals.sagepub.com/doi/10.1177/...

#biomarker #cancerprognosis #lungcancer #oncology #openaccess

Biovica Q3 Earnings call #biovicb #investors #oncology#biomarker #pharma #breastcancer

Register for our upcoming Q3 Earnings call taking place:
Wednesday 18th March, 2025 at 15:00 CET.

Register here: http://bit.ly/4rqjH3I

Presenters are:
Anders Rylander, CEO
Anders Morén, CFO

#biovicb #investors #biomarker #pharma

Neto & Pinho show that grip force variability analyzed with #deeplearning can serve as a novel #biomarker to accurately distinguish mid-stage #Parkinson's disease patients from healthy older adults. doi.org/10.1016/j.ne... #MachineLearning #NeuroMarkers #Neurology #MedSky #neuroskyence

Kidney Injury #Urine #Biomarker Normal Ranges in #Children

#VisualAbstract by Susan Thanabalasingam

www.kireports.org/article/S2468-0249(26)02...