🔜 #ELCC26 @myesmo.bsky.social
🔥Perioperative treatments for early lung cancer
☑️ #AGA #Adjuvant #Neoadjuvant #Perioperative #Biomarker
🎙️Chair: Dr. Enriqueta Felip, Dr. James Spicer
@oncoalert.bsky.social LARVOL #LCSM

Building protection against infectious diseases with nanostructured vaccines A multi-disciplinary research team at the Wyss Institute at Harvard University, Dana-Farber Cancer Institute, and collaborating institutions leveraged their recently developed highly versatile…

Building protection against #infectious #diseases with nanostructured #vaccines ...

| #adjuvant | #DNA | #virus | #infections | #immunity | #microbiology | By @wyssinstitute.bsky.social via eurekalert .org

Optimizing an avian #influenza #vaccine using a novel Bacterial Enzymatic Combinatorial Chemistry (BECC) TLR4 #adjuvant

Optimizing an avian #influenza #vaccine using a novel Bacterial Enzymatic Combinatorial Chemistry (BECC) TLR4 #adjuvant, etidiohnew.blogspot.com/2026/03/opti...

Scientists show that 6 or 12 months of #adjuvant #icotinib significantly improves DFS, OS, and BMFS in resected stage II–IIIA #EGFR-mutated #NSCLC with good tolerability, supporting icotinib as a post-chemotherapy option. #medsky

#OpenAccess in #STTT: doi.org/10.1038/s413...

Liquid biopsy-guided adjuvant therapy in bladder cancer Adjuvant atezolizumab improved survival outcomes in patients with muscle-invasive bladder cancer who had no radiographic disease but had detectable circulating tumor DNA in their blood.

⭐Research highlight: #Adjuvant #atezolizumab improved survival outcomes in patients with muscle-invasive #bladdercancer who had no radiographic disease but had detectable circulating tumor DNA in their blood. #IMvigor011 #liquidbiopsy #ESMO NEJM.org
https://www.nature.com/articles/d41591-025-00065-1

6/8 The immune response was able to recognize multiple strains of #H5N1.

Co-lead author Dr. Meagan #Deming said the #adjuvant is also key: it "might allow for lower doses of the vaccine, which could make our current vaccine stocks available to more people in the event of an outbreak."

#Pandemic

Silica Water: Your Daily Defense Against ALUMINUM Toxicity In today's episode we're diving deep into the dangers of aluminum, a toxic light metal found in sources like vaccines, food, and drinking water. Experts like Dr. Chris Exley and Dr. Dennis Crouse argue that chronic exposure, particularly accumulating in the brain, contributes to severe neurodegenerative and neurodevelopmental conditions such as Alzheimer’s disease, multiple sclerosis, autism, and epilepsy. We discuss how aluminum loads exceed the body’s excretory capacity, causing catastrophic changes in brain chemistry. Fortunately, we explore the science-backed solution: consuming silica-rich mineral water. This water binds with aluminum and facilitates its urinary elimination via the kidneys, offering an effective "philosophy for living in the Aluminum Age". Learn how to mitigate your exposure and utilize this simple remedy. Podcast Resources - Yoho, R. (2025, February 1). 344. HOW TO ELIMINATE ALUMINUM FROM YOUR BODY [Podcast Transcript/Article]. Surviving Healthcare. - Exley, C. (2020). Imagine You Are An Aluminum Atom: Discussions With Mr. Aluminum. (Book). - Crouse, D. (2016). Prevent Alzheimer's, Autism and Stroke: With 7-Supplements, 7-Lifestyle Choices, and a Dissolved Mineral. (Book) - Crouse, D. (2018). Silica Water, the Secret of Healthy Longevity in the Aluminum Age. (Book) - Crouse, D. (2022). Finding a Cause and Potential Cures for Alzheimer's Disease: Climbing the Ladder of AD Causation. (Book) - Exley, C. (2024, September 23). Aluminium (Aluminum) Hydroxyphosphate Sulphate and the HPV Vaccine. Dr’s Newsletter. Substack - Exley, C. (2024, August 14). Aluminium or Aluminum: Whatever your preference, it is in every cell of your body. Dr’s Newsletter. Substack - Exley, C. (2025, January 5). Fish Behaving Badly: Is aluminium antisocial too? Dr’s Newsletter. Substack - Handley, J. B. (2024, September 2). International scientists have found autism's cause. What will Americans do? J.B. Handley Blog. Substack - Mold, M., Cottle, J., & Exley, C. (2019). Aluminium in Brain Tissue in Epilepsy: A Case Report from Camelford. International Journal of Environmental Research and Public Health, 16(12), 2129. DOI: 10.3390/ijerph1612212919.... - Exley, C. (2017). Aluminum Should Now Be Considered a Primary Etiological Factor in Alzheimer’s Disease. Journal of Alzheimer’s Disease Reports, 1, 23–25. DOI: 10.3233/ADR-17001023 - Exley, C., & Mold, M. J. (2019). Aluminium in human brain tissue: how much is too much? JBIC Journal of Biological Inorganic Chemistry, 24, 1279–1282. DOI: 10.1007/s00775-019-01710-026 - Mold, M. J., & Exley, C. (2022). Aluminium co-localises with Biondi ring tangles in Parkinson’s disease and epilepsy. Scientific Reports. - Shaw, C. A., & Tomljenovic, L. (2011). Aluminum Vaccine Adjuvants: Are they Safe? Current Medicinal Chemistry - Shaw, C. A. et al. (2007). Aluminum Adjuvant Linked to Gulf War Illness Induces Motor Neuron Death in Mice. - Mold, M., Umar, D., King, A., & Exley, C. (2018). Aluminium in brain tissue in autism. Journal of Trace Elements in Medicine and Biology, 46, 76–82.

📣 New Podcast! "Silica Water: Your Daily Defense Against ALUMINUM Toxicity" on @Spreaker #adjuvant #aluminum #alzheimers #autism #brain #detox #elimination #epilepsy #exposure #inflammation #longevity #mineral #ms #neurotoxin #parkinsons #silica #silicic #toxicity #vaccines #water

Public health experts wary as Trump administration takes aim at aluminum in vaccines The Trump administration is considering removing aluminum from vaccines, a move opposed by most public health experts.

Many thanks to Rob Stein of @NPR.org for interviewing me re Alum #adjuvant and optimization of #vaccines: www.npr.org/2025/10/28/n...

Mn-LNP Co-Delivery System Enhances VZV Vaccine Efficacy Mn-coordinated lipid nanoparticles (Mn-LNPs)-encapsulated varicella zoster virus (VZV) glycoprotein E antigen and CpG adjuvant enhances VZV vaccine efficacy.

This study developed manganese-coordinated #LipidNanoparticles to co-deliver #VaricellaZosterVirus (VZV) antigen & CpG #adjuvant, significantly boosting CD4+/CD8+ T cell & IgG2b responses vs aluminum adjuvant, offering a strategy to enhance VZV #vaccine efficacy.

#OpenAccess: tinyurl.com/25eta4n2

#Flamingo-01 #GBG111: a global phase III, randomized, placebo-controlled study investigating the GLSI-100 immunotherapy in HLA-A*02-positive and HER2/neu-positive breast cancer patients who remain at high risk of #recurrence after completing both #neoadjuvant and #adjuvant standard therapy.

Coming up at #ASTRO25: MSK’s Dr. Nancy Lee will discuss #neoadjuvant and #adjuvant pembrolizumab plus standard of care in resectable locally advanced head and neck squamous cell #carcinoma. @astro-org.bsky.social

Tuesday, 9/30 | 2:30 p.m. PDT

Learn more: bit.ly/4pNSt7K

This study shows that #adjuvant #Icotinib for 6/12 months after #chemotherapy improves DFS & OS in patients with resected #EGFR-mutated stage II–IIIA #NSCLC, with manageable safety, supporting it as a potential treatment option. #medsky

#STTT #OpenAccess: doi.org/10.1038/s413...

It has a different #adjuvant.
Novavax Nuvaxovid covid vaccine has Matrix-M adjuvant.
Arexvy RSV vaccine has AS01E adjuvant, 25µg/dose. Given as 1 dose (1-3 years interval if boosted for more winter seasons).
SHINGrix SHINGles shot has AS01B adjuvant, 50µg/dose. Given as 2 doses, 2-6 months interval.

My brain has always annoyed me by reading “M1NED” as “mined” conjuring images of dangerous places to tread. I’m starting to think it was right all along.

#RenalCellCarcinoma #KidneyCancer #kcsm #adjuvant #ANZUP25

the sun is shining through the trees and a plant is growing out of the ground in the forest . Alt: the sun is shining through the trees and a plant is growing out of the ground in the forest .

Belief in magic:
#spiritual #adjuvant
gets you through dark days

#Senryu #senryusunday #3lines
#haikuchallenge #vss365 #haiku

Collectively, we,
The adjuvant therapy,
To this lump, the Dump.
#dailyhaikuchallenge #adjuvant #haiku #senryu #poem #writing #writingcommunity #resist

Innovation packaging chez MAPEI : les sacs 100 % papier sans film plastique ! MAPEI passe au sac 100 % papier sans film plastique : une innovation au service de l’environnement !

VIDÉO | Innovation packaging chez MAPEI : les sacs 100 % papier sans film plastique ! buff.ly/nrRHLSv #Industrie #Colle #Ragréage #Mortier #Adjuvant #Packaging #Vidéo

Scientists behind a study suggesting #GSK's respiratory syncytial virus (#RSV) #vaccine could be protective against #dementia have said the #adjuvant used in the shot may be responsible.

pharmaphorum.com/news/could-v...

#ESMOBreast25: Final analysis of APHINITY at median 11.3 years’ follow-up confirms an OS benefit with #adjuvant pertuzumab added to trastuzumab plus chemotherapy in patients with HER2+ operable #BreastCancer.

Read more in the #ESMODailyReporter

🔗 ow.ly/Bc9N50VTa7G

Linking vaccine adjuvant mechanisms of action to function We review mechanisms of action underlying the function of vaccine adjuvants and knowledge gaps to be addressed.

Elana Ben-Akiva, Asheley Chapman, @tianyangmao.bsky.social, & Darrell Irvine describe recent advances in our understanding #vaccine #adjuvant mechanisms of action!

Both in the #adjuvant (cDC1 treatment after tumor resection) and particularly in the #neoadjuvant (cDC1 vaccine while the tumor is still present) setting, cDC1 vaccines are highly effective in preventing cancer #recurrence after primary tumor resection.
#immunosky #cancersky (4/7)

Adjuvant de la chatte

Un adjuvant est une substance ajoutée à un produit pour améliorer son efficacité ou ses propriétés. #Adjuvant #Efficacite #Proprietes #Substance #Amelioration

SciTech Chronicles. . . . . . . . .Mar 7th, 2025 Those who make peaceful revolution impossible will make violent revolution inevitable. Vol II No 60 336 links Curated Engineered cartilage f...

SciTech Chronicles. . . . . . . . .Mar 7th, 2025

bit.ly/stc030725

#articular #cartilage #mature #osteoarthritis #latitudinal #air #currents #meridional #Australia #shatter-cones #36,000km/h #cratons #norovirus #adenovirus #genotypes #adjuvant #35,000ft #MEER #adaptations #hadal

Linking vaccine adjuvant mechanisms of action to function We review mechanisms of action underlying the function of vaccine adjuvants and knowledge gaps to be addressed.

This week in #Science #Immunology: A comprehensive review from Darrell Irvine and co-authors on recent advances in understanding #vaccine #adjuvant mechanisms of action, which could guide adjuvant design for vaccines against emerging and challenging pathogens:

Perioperative or postoperative adjuvant oxaliplatin with S-1 versus adjuvant oxaliplatin with capecitabine in patients with locally advanced gastric or gastro-oesophageal junction adenocarcinoma under... Consistent with the initial analysis of 3-year disease-free survival, the extended 5-year overall survival analysis from the RESOLVE trial confirmed the survival advantage of perioperative-SOX and adj...

NEW – final results from RESOLVE:

Perioperative or postoperative #adjuvant #oxaliplatin with S1 vs adjuvant oxaliplatin with capecitabine in patients with locally advanced gastric or gastro-oesophageal junction adenocarcinoma

#gastriccancer #gicsm

www.thelancet.com/journals/lan...

Dr Jean-Francois Pouliot #immunotherapy expert @regeneron.com talks #neoadjuvant + #adjuvant #LAG3 + #PD1 for respectable early stage #NSCLC /question: based on #ODAC @fda.gov contributions of components #BRIDGE2024 @sitcancer.bsky.social @alkpositiveuk.bsky.social @lungcancerresearch.bsky.social

Dr. Michael Lowe #cancer #immunotherapy expert @winshipatemory.bsky.social presents summary of #neoadjuvant & #adjuvant anti- #PD1 #cemiplimab for recurrent #SCC /Discuss- move to 2 cycles & no delay to surgery/ #Bridge2024 @regeneron.com @sitcancer.bsky.social

Early versus deferred use of CDK4/6 inhibitors in advanced breast cancer - Nature The phase 3 SONIA trial challenges the benefits of using cyclin-dependent kinase 4 and 6 inhibitors as a first-line compared with second-line treatment.

Provocative data from #SONIA (initially presented at #ASCO23) suggest no difference in using #CDK4/6 inhibitor early vs. deferred in ER+ #mBC; however, #CDK4/6 will likely continue moving to #adjuvant tx so this question might become less relevant www.nature.com/articles/s41...