¿Qué vuelve más agresivos a los tumores de cuerdas vocales? #Cancer #Tumores #CuerdasVocales #Oncologia #Biotecnologia #Investigacion #Salud #Ciencia #Medicina #Metastasis #EGFR #Cx26 #felizmiercoles #1deabril donporque.com/que-empeora-...
"Any drug that targets #EGFR will, to some degree, have these #sideeffects." - Tejas Patil
#LungCancerTargetedTherapies #LungCancer #TargetedTherapies
Figure 1. Clinical Features of a Patient With Germline Epidermal Growth Factor Receptor L858R Variants; A) Skin with horizontal lines. B) Feet with Palmoplantar keratoderma. C) Hand with Leukonychia. D) Woolly hair on a person wearing glasses and a mask.
Activating #EGFR variants were identified in early-onset, severe generalized #AcanthosisNigricans with pulmonary nodules; EGFR inhibitor therapy improved both skin and lung disease. ja.ma/4rKi9CP
#Tetraspanin CD82 shapes #EGFR signaling outcomes through nanoscale receptor organization. New study from Sebastian Restrepo Cruz, Jennifer M. Gillette and colleagues @unm.edu: rupress.org/jcb/article/...
#Cancer #Biophysics #Membrane #Lipid #CellSignaling
🎨Science Visuals | 🎯Targeted therapies are transforming treatment for #ColorectalCancer (#CRC)
🔸Key approaches include #EGFR inhibitors like #Cetuximab & #Panitumumab and #VEGF inhibition with #Bevacizumab.
🚫#Tumor growth and #angiogenesis.
#Cancer #CancerResearch #Oncology
Restrepo Cruz, Gillette et al. @unm.edu reveal the CD82 #tetraspanin scaffold regulates the nanoscale organization of #EGFR on the plasma membrane, modulating its multimerization & inhibiting ligand-independent receptor phosphorylation upstream of cellular proliferation rupress.org/jcb/article/...
In @jcb.org, the Gillette lab @unm.edu reveals the CD82 #tetraspanin scaffold regulates the nanoscale organization of #EGFR on the plasma membrane, modulating its multimerization & inhibiting ligand-independent receptor phosphorylation upstream of cellular proliferation rupress.org/jcb/article/...
Author Interviews, March 9 • 16 MIN, Wait Time Modifications for Black Kidney Transplant... JAMA Internal Medicine Author I..., with the letters JN in a circle and a play button.
Eve Rittenberg, MD, spoke with Rohan Khazanchi, MD, MPH, and Ebony Boulware, MD, MPH, about the impact of recalculating waitlist times for Black candidates using race-neutral estimated glomerular filtration rate (#eGFR) equations.
Listen now: ja.ma/4cIyNxY
5 innovadores medicamentos chinos, incluyendo inhibidores de:
🧬 KRAS G12C
🧬 EGFR de tercera generación
🧬 EGFR exon 20
#Fulzerasib #Sunvozertinib #Limertinib #Glecirasib #Garsorasib #Cáncer #Oncología #TerapiaDirigida #InnovaciónMédica #KRAS
#KRASG12C #EGFR #EGFRexon20 #DengYueMedicinasEnHongKong
ALSO IN THIS ISSUE
When “normal” isn’t normal: The low and high ends of #eGFR
Is your #bellyfat something to worry about? Depends where it is A #contactlens that monitors #intraocularpressure
open.substack.com/pub/sensitiv...
#sensitiveandspecific #diagnostics #kidneyfunction #ontargetpodcast
🧬 5 terapias dirigidas innovadoras de China
🎯 5 mecanismos clave
🌍 1 objetivo: transformar el tratamiento del cáncer de pulmón
#CáncerDePulmón #CPNM #SaludPulmonar #TerapiaDirigida #Biotecnología #EGFR #ALK #ROS1 #Antiangiogénesis #PD1 #VEGF #InnovaciónChina #DengYueMedicinasEnHongKong
iCARE eGFR pathway from development to implementation.
Early #KD detection matters: Implementing a novel #eGFR equation for youth with T2D into their diabetes care. #slowdiseaseprogression #pediatricnephrology
@umanitoba.bsky.social @csnscn.bsky.social
doi.org/10.1177/2054...
🎯 4 dianas clave.
🧬 Tratamiento de precisión.
🌍 Impacto global.
📎 Más información: dengyuepharma.com
📧 info@dengyuemed.com
#CáncerDePulmón #CáncerDePulmónNoMicrocítico #NSCLC #Oncología #OncologíaClínica #SaludGlobal #EGFR #ALK #PD1 #PDL1 #KRAS #KRASG12C #DengYueMedicinasEnHongKong
Register:
give.cancergrace.org/event/lung-c...
Support free patient education 💙 #LungCancer #EGFR #HER2
eGFR = kidney function estimate
Not a direct readout of kidney damage
You can have normal/stable eGFR while inflammation, fibrosis, or tubular injury progresses.
Pair eGFR with biomarkers + albuminuria to move from staging → risk prediction.
#CKD #eGFR #KidneyHealth #PrecisionMedicine #Biomarkers
🔢 eGFR Calculator – Instantly assess kidney function & med dosing. 🩺 Supports CKD-EPI & MDRD equations for quick, reliable results. ⚡#eGFR #KidneyHealth
https://go.docspot.info/EGFR-Bluesky
Measurement error in nephrology /2:
- glucose (both serum and urine) affects serum creatinine and urinary creatinine levels
- consequences affect #CKD staging by #eGFR and #uACR
www.sciencedirect.com/science/arti...
Intriguing new research: Triple-targeted therapy shows unprecedented efficacy in early pancreatic cancer models. Read here: t.ly/kTeMr #PDAC #KRAS #STAT3 #EGFR #OncologyNews #OncologyNetworkAustralia #Spain #CNIO #OncSky #MedSky #CanSky
Tumore al pancreas: la cura spagnola funziona davvero? #TumorePancreas #Cancro #Oncologia #RicercaMedica #TriplaTerapia #KRAS #STAT3 #EGFR #Barbacid #PDAC #Salute #ClinicalTrials #Italia #Domandalo domandalo.com/spagna-cura-...
Implementing #KDIGO 2024 Through Laboratory-estimated #Glomerular Filtration Across Ages #eGFR
#VisualAbstract by @DrPallaviPrasad
www.kireports.org/article/S2468-0249(25)00...
Akeso Biopharma presenta la BLA de ivonescimab (anticuerpo biespecífico PD-1/VEGF) ante la FDA
📩 info@dengyuemed.com
🔗https://dengyuepharma.com
#Oncología #CáncerDePulmón #NSCLC #CPNM #EGFR #PD1 #VEGF #AnticuerpoBiespecífico #Ivonescimab #SummitTherapeutics #FDA
This review analyzes #EGFR in #TNBC, identifying genomic co-factors, and underscoring the need to shift from failed monotherapies to #Nanoparticle-mediated multi-targeted strategies for more precise #PersonalizedMedicine.
#OpenAccess: doi.org/10.1016/j.ge...
Amplificación de la mutación de resistencia al anticuerpo antirreceptor del factor de crecimiento epidérmico puede conferir resistencia a estos anticuerpo, por lo que puede ayudar a guiar el uso apropiado de estos anticuerpos en la práctica clínica #RAS #eGFR #CRC ascopubs.org/doi/full/10....
Estudio SACHI confirma beneficio de savolitinib + osimertinib en NSCLC EGFR/MET
📩 info@dengyuemed.com
🔗https://dengyuepharma.com
#SACHI #NSCLC #EGFR #METamplification #MayoristaDeImportaciónYExportaciónDeMedicamentosDeChina
Population-based estimated Glomerular Filtration Rate distributions and associated health outcomes provide opportunities for early identification of and primary prevention of chronic kidney disease
doi.org/10.1016/j.kint.2025.11.009
#NephSky #MedSky #OpenAccess #chronickidneydisease #egfr #CKD
The image shows clinical features of a patient with Germline Epidermal Growth Factor Receptor L858R Variants. (A) Clinical image of case patient 1, (B) Palmoplantar keratoderma, (C) Leukonychia, (D) Woolly hair.
Activating #EGFR variants were identified in early-onset, severe generalized #AcanthosisNigricans with pulmonary nodules; EGFR inhibitor therapy improved both skin and lung disease. ja.ma/4bw0Rnp
Targeting the STARD4/EGFR axis inhibits HCC growth & overcomes lenvatinib resistance.
#HCC #DrugResistance #EGFR #CancerTherapeutics #Lenvatinib
www.sciencedirect.com/science/arti...
Heterogeneity of #eGFR Slopes According to #Etiology, eGFR and UACR in a Large Cohort of #CKD #Patients
#VisualAbstract by Augusto Cesar S Santos Jr
www.kireports.org/article/S2468-0249(25)00...
The January issue is now online!
👉 Read our latest articles! 🚨 Including four new reviews!
🔗 onlinelibrary.wiley.com/toc/13652796/2026/299/1
#Senotherapeutics #metabolic #Bioenergetics #lipid #Alzheimers #tuberculosis #obesity #cancer #cardiovascular #SLE #anticoagulant #eGFR #BMI #adolescence
