#Tetraspanin CD82 shapes #EGFR signaling outcomes through nanoscale receptor organization. New study from Sebastian Restrepo Cruz, Jennifer M. Gillette and colleagues @unm.edu: rupress.org/jcb/article/...

#Cancer #Biophysics #Membrane #Lipid #CellSignaling

Restrepo Cruz, Gillette et al. @unm.edu reveal the CD82 #tetraspanin scaffold regulates the nanoscale organization of #EGFR on the plasma membrane, modulating its multimerization & inhibiting ligand-independent receptor phosphorylation upstream of cellular proliferation rupress.org/jcb/article/...

In @jcb.org, the Gillette lab @unm.edu reveals the CD82 #tetraspanin scaffold regulates the nanoscale organization of #EGFR on the plasma membrane, modulating its multimerization & inhibiting ligand-independent receptor phosphorylation upstream of cellular proliferation rupress.org/jcb/article/...

Platelet-derived integrin- and tetraspanin-enriched tethers exacerbate severe inflammation Platelet integrin αIIbβ3 is essential for hemostasis, thrombosis, and inflammation. We found that ligation of αIIbβ3 by von Willebrand factor or fibrin under flow triggered its accumulation in plasma ...

This week #JournalClub @labsoap.bsky.social @nature.com #integrin #tetraspanin #migration www.science.org/doi/10.1126/...

Announcement: Particle Metrix will join SelectBIO EV Research 2025 – Ross Jacobson will present on ZetaView® Evolution.

We’re heading to #SelectBio Innovations in #EVresearch 2025!
Join @particle-metrix.bsky.social Nov 17–18 in Laguna Hills, CA.
🎤 Don’t miss Ross Jacobson’s talk: “ZetaView® Evolution – Your EV Solution” + a live demo featuring our #Tetraspanin Kits!
#ZetaView #NTA #ExtracellularVesicles #EVs

Matching Day #CEEVEC - April 28, 2025

Don't miss the chance to experience the @particle-metrix.bsky.social ZetaView® family and our new F-NTA Detection Antibodies live!
canceropole-paca.com/agenda/match...

#wearecanceropole #ExtracellularVesicles #ZetaView #particlemetrix #FNTA #Tetraspanin

📣𝗦𝐀𝐕𝐄 𝐓𝐇𝐄 𝐃𝐀𝐓𝐄!
We are at @isev.org Annual Meeting 2025 in Vienna, Austria.
Be sure to visit us from April 24-27, 2025 at the @particle-metrix.bsky.social booth and be excited, beneath our new F-NTA EV #Tetraspanin Detection Kits, we have further news to share.
#ISEV2025 #ExtracellularVesicles #NTA

#Klotho shedding from the kidneys:
the calcium-sensing receptor induces #ADAM10-mediated cleavage of membrane-bound Klotho.
This study finds that #tetraspanin 5 contributes to this process.

➡️bit.ly/4iaVWZF

#cellsignaling