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#ADAM10
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Signal Transduction and Targeted Therapy
Signal Transduction and Targeted Therapy
@sigtrans-sttt.bsky.social
3 weeks ago
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Researchers combine #TDDFT and docking to design theranostic probes for #AlzheimersDisease, showing aromatic delocalization and IAF tagging enhance optical response and selective binding to BACE1, #ADAM10, and neprilysin.

#OpenAccess in #STTT: doi.org/10.1038/s413...

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Signal Transduction and Targeted Therapy
Signal Transduction and Targeted Therapy
@sigtrans-sttt.bsky.social
1 month ago
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This study compares natural #scaffolds #Oridonin and ammosamide B as #theranostic probes for #Alzheimers targets, revealing aromaticity-driven optics and tunable binding to BACE1, #ADAM10, and #Neprilysin for early detection and precision intervention.

#STTT: doi.org/10.1038/s413...

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Cláudio Gomes Lab - Protein Misfolding in Disease
Cláudio Gomes Lab - Protein Misfolding in Disease
@claudiogomeslab.bsky.social
1 year ago
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Looking forward #ADAM10 kick-off 🇸🇪 3 days of all things amyloid and great opportunity to meet old friends and making new ones! Thanks @professorpernilla.bsky.social and Elin Esbjorner et al for such a great program. Reach out if you are around
www.chalmers.se/en/conferenc...

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