🌅 #Research #Alert
Single-cell transcriptomics reveals #heterogeneity and #immune #microenvironment in lymphatic #metastasis of head and neck squamous cell #carcinoma

Access here: www.nature.com/articles/s41...
@springernature.com #Genes & #immunity

Treatment and risk of metastases in trachea, lung or bronchial cancer #metastasis #cancer #oncology
... Continue to: youtube.com/shorts/MofBX...

Descubren cómo el cáncer altera el cerebro y hace metástasis El CNIO revela cómo el cáncer secuestra defensas del cerebro para expandirse y sitúa a ibudilast como freno posible a la metástasis cerebral. El hallazgo del Centro Nacional de Investigaciones Oncológ...

Descubren cómo el cáncer altera el cerebro y hace metástasis #Cancer #Metastasis #MetastasisCerebral #CNIO #Investigacion #Salud #Cerebro #Oncologia #Ibudilast #LauraAlvaroEspinosa #ManuelValiente #FelizMiercoles #25deMarzo donporque.com/como-el-canc...

This review shows how #RNAbindingProteins and #circularRNAs form regulatory networks driving #tumor traits like #metastasis & #DrugResistance, offering therapeutic insights via RNA technologies to reshape the #TumorMicroenvironment.

#OpenAccess: doi.org/10.1016/j.ge...

Ageing promotes metastasis via activation of the integrated stress response - Nature Ageing reprograms the evolutionary trajectory of KRAS-driven lung adenocarcinoma, limiting primary tumour growth while promoting metastatic dissemination through epigenetic activation of the integrate...

This week #JournalClub @labsoap.bsky.social @nature.com #ageing #metastasis #stressresponse www.nature.com/articles/s41...

AI tool predicts cancer metastasis risk with high accuracy Researchers from the University of Geneva (UNIGE) have developed an artificial intelligence tool that can predict whether cancer will spread, providing about 80% accuracy. The tool, MangroveGS, uses gene patterns found in colon cancer cells to predict metastasis risk. By studying gene signatures and their interaction within cancer cells, the team was able to develop a model that works across multiple cancer types, including stomach, lung, and breast cancers. This breakthrough tool could transform how doctors assess metastasis risk and make treatment decisions, enabling more personalized and targeted care. The AI model analyzes tumor samples, sequences RNA, and generates a metastasis risk score that can be securely shared with doctors and patients. This innovation could reduce unnecessary treatments and side effects while ensuring that high-risk patients receive the appropriate care. Additionally, it offers potential to optimize clinical trial participant selection, improving the effectiveness of cancer treatments.

AI tool predicts cancer metastasis risk with high accuracy

🤖 IA: It's not clickbait ✅
👥 Usuarios: It's not clickbait ✅

#ai #cancer #metastasis

View full AI summary:

👋Our March issue is out!
Cover: #Adipose – #tumor in #immune escape

👉Reviews on: #metabolism #hematopoiesis ; #amnion ; #brain #lipids
🔬 #mitochondria #LipidDroplets #aging #autophagy #mechanobiology #neurodegeneration #ferroptosis #chromatin #metastasis & more!
www.nature.com/ncb/volumes/...

What stage is cancer typically in if it has spread to distant organs? A) Stage I B) Stage II C) Stag What stage is cancer typically in if it has spread to distant organs? A) Stage I B) Stage II C) Stag

What stage is cancer typically in if it has spread to distant organs?
A) Stage I
B) Stage II
C) Stage III
D) Stage IV
#cancerstages #oncology #metastasis #medicaleducation ... Continue to: www.facebook.com/113009240922...

Ageing promotes metastasis via activation of the integrated stress response - Nature Ageing reprograms the evolutionary trajectory of KRAS-driven lung adenocarcinoma, limiting primary tumour growth while promoting metastatic dissemination through epigenetic activation of the integrate...

#Ageing promotes #metastasis via activation of the integrated #stress response
doi.org/10.1038/s415...

Epigenetics Update - Ageing promotes metastasis via activation of the integrated stress response go.nature.com/4cGv6c7

Clotilde Wiel and Volkan I. Sayin reporting in Nature

#Epigenetics #Aging #Metastasis #Cancer
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Perfect for cancer, immunology, and aging research; epigenometech.com

Epigenetics Update - Paired patient-derived organoids reveal transcription factor-driven epigenetic remodeling in breast cancer metastasis bit.ly/4cSoZ4r

#Epigenetics #Organoids #BreastCancer #Metastasis #PDOs
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Gain deeper insights into gene regulation; epigenometech.com

This review highlights the role of #FattyAcidOxidation in #cancer, showing how mitochondrial regulation of energy and signaling drives #tumor growth and #metastasis, positioning FAO as a promising therapeutic target.

#OpenAccess: doi.org/10.1016/j.ge...

Key Genes Involved in the Beneficial Mechanism of Hyperbaric Oxygen for Glioblastoma and Predictive Indicators of Hyperbaric Oxygen Prolonging Survival in Glioblastoma Patients

This study shows that #HBOTherapy exerts #Antitumor effects in #Glioblastoma, promoting #Apoptosis, inhibiting #Inflammation, reducing #CellProliferation, suppressing #TumorGrowth & #Metastasis, regulating #Vascularization, & thus prolonging patient survival. #medsky

Read: doi.org/10.1007/s115...

Treatment and risk of metastases in trachea, lung or bronchial cancer #metastasis #cancer #oncology
... Continue to: youtube.com/shorts/MofBX...

Bladder cancer: treatment and risk of metastasis #bladder #bladdercancer #oncology #metastasis Bladder cancer: treatment and risk of metastasis #bladder #bladdercancer #oncology #metastasis

Bladder cancer: treatment and risk of metastasis #bladder #bladdercancer #oncology #metastasis ... Continue to: www.facebook.com/reel/1855406...

New AI Model Predicts Cancer Spread With Incredible Accuracy Scientists have developed an AI system that analyzes complex gene-expression signatures to estimate the likelihood that a tumor will spread.

New AI Model Predicts Cancer Spread with Incredible Accuracy | #cancer #metastasis #AI

Androgen Receptor Promotes Lung Cancer Metastasis by Modifying the miR23a-3p/EPHB2 Pathway

This study demonstrates that the AR promotes #LungCancer #Metastasis by modulating #miRNA 23a 3p/#EPHB2 signaling, suggesting that targeting this pathway could provide novel #therapeutic strategies to inhibit metastatic progression. #medsky

To read: doi.org/10.1007/s115...

Scientists reveal PKCη as a driver of #TNBC #metastasis by suppressing Hippo signaling & activating YAP, while a uORF-encoded peptide degrades PKCη, highlighting a novel therapeutic vulnerability in aggressive #BreastCancer.

#OpenAccess in #STTT: doi.org/10.1038/s413...

Important insight into #gastriccancer #metastasis. This study shows how #tumor-secreted Wnt ligands activate stromal fibroblasts to produce hyaluronan, creating a supportive metastatic niche in the #liver. www.linkedin.com/posts/drmelv...

Scientists show #CyclicdiGMP inhibits #breastcancer #metastasis by binding #PSMD3, disrupting PSMD3–TBK1 interaction, and suppressing NF‑κB signaling, positioning PSMD3 as a therapeutic target. #Antimetastatic @tulanemedicine.bsky.social

#OpenAccess #STTT: doi.org/10.1038/s413...

An overview of #OncolyticVirus (OV) therapy, detailing multimodal mechanisms targeting #Tumorigenesis and #Metastasis while addressing current clinical challenges and future perspectives for enhanced efficacy.

#STTT #OpenAccess: doi.org/10.1038/s413...

TGF-β in tumor development and progression: mechanisms and therapeutics - Molecular Biomedicine Transforming growth factor beta (TGF-β) is a pleiotropic cytokine and participates in multiple cellular processes, such as cell development, proliferation, epithelial mesenchymal transition (EMT), and...

#Review
#TGF-β in #tumor development and progression: mechanisms and therapeutics doi.org/10.1186/s435...

Authored by researchers from #SoochowUniversity

#signaling #TME #Metastasis #immunity #TargetedTherapy

#Highlight in #MedComm_Oncology
#Metabolic Reprogramming of the Pre-Metastatic Niche: A Sweet Spot for Anti-#Tumor #Immunity doi.org/10.1002/mog2...

The highlighted article in @CellCellPress : doi.org/10.1016/j.ce...

#LowCarbohydrateDiet #Lung #Metastasis #macrophage #NKcell

Check out the awesome highlight (+ video) of our recent work on the #biophysics of #metastasis published by Le Point, by O.HERTEL

🔗 lnkd.in/eywzr8kn

🖥️ dai.ly/xa0dwds

Such a blast to see our #zebrafish 🐠 experiments making the (web) front page (but there are also 🐁 ones in the original paper 😜)

#MASLD increases #PDAC risk & #livermetastasis by creating an #immunosuppressive niche driven by the MIF–CD44 axis, which enhances PDAC cell migration, stemness, and adhesion, while MIF inhibition reduces #metastasis, highlighting a targetable pathway.

#STTT: doi.org/10.1038/s413...

Breast cancer cell clusters The Image this month shows a mechanism that mediates the formation of breast cancer cell clusters and promotes cancer metastasis.

Check out #FromtheLabs' new Image of the Month! Image courtesy of the C. Cheng lab. @bcmhouston.bsky.social @bcmgenetics.bsky.social #TripleNegativeBreastCancer #Metastasis #BCMCancerCenter #BCMpostdoc blogs.bcm.edu/2026/02/26/f...

Single-cell exome sequencing reveals polyclonal seeding and TRPS1 mutations in colon cancer metastasis.
High-resolution insight into tumor evolution.
doi.org/10.1038/s413...
#ColonCancer #SingleCellSequencing #CancerGenomics #Metastasis #TRPS1 #TumorEvolution

Lindqvist-type Polyoxometalates Act as Anti-breast Cancer Drugs via Mitophagy-induced Apoptosis

A novel Lindqvist-type polyoxometalate MO-4 shows strong anti-breast cancer activity by raising #MitochondrialROS to trigger #mitophagy and #apoptosis, reducing #tumor growth and #metastasis in vivo, highlighting promise as a therapeutic candidate.

Read: doi.org/10.1007/s115...

¿Cómo puede el ICAM dar el alta con cáncer con metástasis? A un catalán con cáncer metastásico le dan el alta: el choque entre informes del Clínic, el ICAM y la vía judicial que se abre en Barcelona. A Pepe Espino, 54 años, le comunicaron en Barcelona algo qu...

¿Cómo puede el ICAM dar el alta con cáncer con metástasis? #ICAM #INSS #SeguridadSocial #IncapacidadPermanente #BajaLaboral #Catalunya #Barcelona #HospitalClinic #Cancer #Metastasis #DerechosLaborales #SaludPublica #21defebrero #felizsabado #Actualidad donporque.com/como-puede-e...

Don't miss her talk!

🗓 When: June 28 – July 1, 2026
📍 Where: Salt Lake City, Utah
👉 Become a member & Save: metastasis-research.org/membership-a...

#MRS2026 #EvanthiaRoussosTorres #BreastCancer #Immunotherapy #TumorMicroenvironment #Metastasis #USC #WomenInScience