Adipogenic transdifferentiation reprograms EMT-high PDAC cells into a post-mitotic adipocyte-like state and limits metastasis - Cell Death & Disease Cell Death & Disease - Adipogenic transdifferentiation reprograms EMT-high PDAC cells into a post-mitotic adipocyte-like state and limits metastasis

Adipogenic transdifferentiation reprograms EMT-high #PDAC cells into a post-mitotic adipocyte-like state and limits metastasis 🧪 idp.nature.com/authorize?re...

The procedures of ESPPW extraction and purification.

🧪 Can natural polysaccharides target pancreatic cancer?

A CJNM study reports that ESPPW from Arthrospira platensis suppresses PDAC growth and induces apoptosis via caspase-3/p53, while downregulating Gal-3 and GPC-6.

Read the full study:
doi.org/10.1016/S187...

#PancreaticCancer #PDAC #CJNM

Excited to share our article in @cp-trendscancer.bsky.social ‘The rationale for targeting nectin-4 in pancreatic cancer‘.
Read more about the significance of #nectin-4 in #PDAC and what’s on the horizon:
www.sciencedirect.com/science/arti...
#PancreaticCancer #NEC4NEOP

Molecular subtypes in pancreatic cancer: from academic promise to clinical reality - Molecular Cancer Pancreatic ductal adenocarcinoma (PDAC) continues to rank among the most lethal malignancies, with five-year survival rates stubbornly below 12%. Over the past decade and a half, transcriptomic analys...

We are thrilled to share our new review article just published in Molecular Cancer Our team explores the journey of molecular subtyping in pancreatic cancer: moving from academic promise to clinical reality. link.springer.com/article/10.1...
#PDAC @ufvmadrid.bsky.social @imas12.bsky.social

A Canada-Italy Potential Trade Marriage Made in Heaven | Corriere Canadese TORONTO - The Prospectors & Developers Association of Canada (PDAC) Convention is the world’s premier annual event for mineral exploration and mining. For the sake of simplification, that is the “upst...

Canada-Italy, the convention of Prospectors & Developers Association (PDAC): the comment by Joe Volpe and photogallery

www.corriere.ca/a-canada-ita...

#Canada #Italia #Pdac

Canada-Italia: matrimonio d’affari voluto dal destino | Corriere Canadese TORONTO - La convention della Prospectors & Developers Association of Canada (PDAC) è il principale evento annuale al mondo per l’esplorazione e l’estrazione mineraria. Per semplificare, parliamo del ...

Canada-Italia, la convention della Prospectors & Developers Association: il commento di Joe Volpe e la fotogallery

www.corriere.ca/canada-itali...

#Canada #Italia #Pdac

Dr. Leanne Brown presents an analysis of MSK-MET tumors #SSO2026 finding chromosome 12p gain may be a key biomarker in pancreatic ductal adenocarcinoma #PDAC, potentially identifying patients most likely to benefit from KRAS-targeted therapies.
@oncoalert.bsky.social

Meanwhile, at #PDAC in Tkaronto, ...
www.instagram.com/reel/DVY-2Xd...
#FreeGrassy #IndigenousRights #RespectTheTreaties #cdnpoli #WaterIsLife #FPIC #UNDRIP

Using integrated #scRNAseq, #Immunofluorescence, and functional validation, this study shows that the #Immunosuppressive #TumorMicroenvironment contributes to tumor aggressiveness in lymphovascular invasion-positive #PDAC.

#OpenAccess: doi.org/10.1016/j.ge...

Ensuring certainty in critical minerals development requires genuine partnership with Anishinabek Nation To the investors, mining companies, government representatives, and stakeholders gathered at the Prospectors & Developers Association of Canada(PDAC) Conference in Toronto, the Anishinabek Nation, whi...

“Any attempt to sideline or bypass our member First Nations will not only jeopardize project success but also undermine the legitimacy of the development process itself.”

#Indigenous #FirstNations #PDAC #mining #ONpoli #cdnpoli #investment

ASCO Publications

Mutaciones KRAS específicas de codón afectan las variables del adenocarcinoma ductal pancreático según la etapa de enfermedad al momento del diagnóstico #KRAS #PDAC ascopubs.org/doi/full/10....

Canada has what the world needs, and the Ministers remarks spoke to our immense natural wealth and technical expertise that will not only help build Canada strong, but diversify our trade and strengthen our partnerships around the world.

#CanadaTrade #PDAC #OakvilleWest

Making the match between 🇩🇪 & 🇨🇦 for resilient critical mineral supply chains & defense cooperation: Busy second day at #PDAC with meetings with Premier Houston, Minister Fedeli, the signing of MoUs with Minister Simard and between rocktechlithium.com & Siemens Canada - and 🇩🇪 Day!

The world wants what Canada has, and our new government is working to get that to market as we Build Canada Strong.

#PDAC #MiningIndustry #OakvilleWest

This #STTT study identified glycolytic heterogeneity within the #PDAC #TumorMicroenvironment and proposes a novel glycolysis-based framework for patient stratification to guide personalized medicine & #PrecisionOncology.

#OpenAccess: doi.org/10.1038/s413...

🇩🇪 technology, engineering & financing to get 🇨🇦 critical minerals to market: Busy day #PDAC in #Toronto.
Thrilled to welcome Parliamentary Secretary Stefan Rouenhoff, who headed an unprecedented 🇩🇪 business delegation representing everything from engineering to recycling!
🇩🇪🇨🇦💪

in front of the metro toronto convention centre, a group of protesters that traveled 2 days from the far north to speak against the planned ring of fire mines in ontario, canada. signs read "water is life" "sturgeon are forever" "neskantaga strong" "neskantaga & attawapiskat will protect our river" Congolese flags in the background.

canadian mining colonizes destroys and kills.
speakers from the #congo, #tigray , and first nations in the #ringoffire speaking of the damages to their land and ppl. while those who profit from murder and pillage network in the convention centre.
#pdac #pdac2026
#shutitdown #canada #environment

A hand holds a "water is life" sign high in the air, with a building and the CN tower in the background

Two people hold a banner that says "Toxic Toronto. Belly of the Beast for the Global Mining Industry" in front of urban buildings on snowy ground

Sunny day to protest #PDAC with @mininginjustice.bsky.social outside the Metro Toronto Convention Centre #NoToMining #MiningIsNotTheFuture

#MASLD increases #PDAC risk & #livermetastasis by creating an #immunosuppressive niche driven by the MIF–CD44 axis, which enhances PDAC cell migration, stemness, and adhesion, while MIF inhibition reduces #metastasis, highlighting a targetable pathway.

#STTT: doi.org/10.1038/s413...

Dual SHP2/MEK inhibition in #PDAC triggers mitochondrial remodeling and #LipidPeroxidase dependency, creating a #ferroptosis vulnerability; combining #GPX4 blockade or withaferin A enhances #tumor suppression across PDAC subtypes.

#STTT: doi.org/10.1038/s413...

Sirios Resources will take the stage at Red Cloud’s Pre-PDAC Mining Showcase to present its expanded James Bay gold strategy.

CEO Dominique Doucet and OVI Mining CEO Jean-Félix Lepage will be presenting at 3:20 PM on Feb 26 in Toronto.

#Gold #Mining #PDAC

investingnews.com/sirios-resou...

Urano Energy will be attending the Prospectors and Developers Association of Canada this March 1-4th! Visit us at Booth 3224, we look forward to seeing you all there. 👏

Learn more: https://pdac.ca/convention-2026

#energy #nuclear #uranium #nuclearenergy #colorado #utah #pdac #pdac2026 #convention

ASCO Publications

Biomarcador basado en la histomorfología con fluoropirimidina vs gemcitabina predice el beneficio del tratamiento y puede guiar la selección para la terapia en pacientes con cáncer de páncreas avanzado #PDAC #Chemotherapy ascopubs.org/doi/full/10....

Individuals tracing a projected image onto a canvas banner. The projected text states "Mining is not the future. The future is...relational"

A hand paints shapes on a canvas banner. Painting supplies sit atop the banner

Getting #PDAC ready with @mininginjustice.bsky.social (MISN) at their teach-in and art build. Join MISN's #MiningIsNotTheFuture rally next Sunday, March 1 at 1pm at the Metro Toronto Convention Centre!

Using a #Multiomics approach, this review defines novel #PDAC molecular subtypes to overcome #TumorHeterogeneity, providing a robust framework for identification of novel #TherapeuticTargets and #PersonalizedTreatment.

#OpenAccess: doi.org/10.1016/j.ge...

Volta Metals featured on The Northern Miner Podcast.

CEO Kerem Usenmez discusses Volta’s positioning within Canada’s critical minerals landscape. Toggle to 25:35 to hear his segment.

Listen here: www.northernminer.com/news/podcast...

#VoltaMetals #PDAC

🚨 Excited to share our latest study in Cancer Discovery! We’ve discovered how myofibroblasts induce neuroplasticity to drive #PDAC progression from early inflammation to invasive carcinoma. 🎗️💜🕸️

Adding Elraglusib to Chemotherapy Extends Survival in Metastatic PDAC Adding elraglusib to chemotherapy significantly increases overall survival in patients with previously untreated metastatic PDAC.

Adding elraglusib, a novel small-molecule inhibitor, to chemotherapy significantly increases OS in patients with previously untreated metastatic #PDAC. Presented at @ascocancer.bsky.social conference #GI26.

https://bit.ly/3ZFQztG

#pancsm

Login / Sign Up – The Oncology Network Free access for registered Healthcare Professionals.

Intriguing new research: Triple-targeted therapy shows unprecedented efficacy in early pancreatic cancer models. Read here: t.ly/kTeMr #PDAC #KRAS #STAT3 #EGFR #OncologyNews #OncologyNetworkAustralia #Spain #CNIO #OncSky #MedSky #CanSky

Countering and colouring against mining convention | Intellect This commentary details the creative media interventions of the collective Beyond Extraction, working to counter the largest mining convention in the world, Prospectors and Developers Association of C...

Published in time for this year's #PDAC, a new article by Beyond Extraction members in the Journal of Environmental Media reflects on our last few years of creative, anti-extractive interventions against Toronto mining hegemony: doi.org/10.1386/jem_...