A urine test that could change the course of bladder cancer care – BioNews Central A new study introduces a non-invasive urine test that can molecularly identify which bladder cancer patients benefit from additional therapy, allowing personalized treatment and avoiding unnecessary care. ...

A new study introduces a #noninvasive #UrineLiquidBiopsy that can molecularly identify which #BladderCancer patients benefit from additional #therapy, allowing #PersonalizedTreatment and avoiding unnecessary care. 
#BladderCancerTreatment

Using a #Multiomics approach, this review defines novel #PDAC molecular subtypes to overcome #TumorHeterogeneity, providing a robust framework for identification of novel #TherapeuticTargets and #PersonalizedTreatment.

#OpenAccess: doi.org/10.1016/j.ge...

HSCT-64, a 64-gene #Transcriptomic #RiskModel enables #Diagnosis-time identification of pediatric #AML patients most likely to benefit from #Transplantation, providing a practical approach for #PersonalizedTreatment.

#OpenAccess: doi.org/10.1016/j.ge...

Blood test may help identify which colon cancer patients benefit from NSAIDs – BioNews Central A blood test may help doctors determine which colon cancer patients should receive anti-inflammatory medication alongside chemotherapy after surgery, potentially improving personalized treatment and o...

A #BloodTest may help doctors determine which #ColonCancer patients should receive #AntiInflammatory medication alongside #chemotherapy after surgery, potentially improving #PersonalizedTreatment and outcomes.

#ColorectalCancer #ColorectalCancerTreatment #NSAIDs

This review summarizes LPA signaling, from #Biosynthesis and receptor pathways to #TherapeuticTargets, and presents an AI model that simulates network dynamics for predictive and #PersonalizedTreatment. #medsky @ou.edu

#STTT #OpenAccess: doi.org/10.1038/s413...

These hernias develop anywhere along the midline of your abdomen. Our surgical approach considers hernia size, location, and your overall health for customized treatment.

#CustomizedCare #SahajHospitalIndore #AbdominalSurgery #PersonalizedTreatment

A Series of Personalized Melatonin Supplement Interventions for Poor Sleep: #feasibility Randomized Crossover Trial for Personalized N-of-1 Treatment Background: Poor sleep (defined by short sleep duration or poor quality) is a common condition with potential serious health consequences. Exogeneous melatonin supplements have been found to effectively improve poor sleep but have also been shown to have heterogeneity of treatment effects (HTEs) between individuals. Personalized N-of-1 trials, in which each participant is the unit of analysis, are ideal for identifying whether a treatment with high HTE is beneficial for each individual patient. Objective: This study aimed to identify the #feasibility, acceptability, and effectiveness of a series of personalized N-of-1 trials of melatonin for poor sleep. Methods: This study consisted of 60 digital, personalized N-of-1 crossover trials comparing the effects of 3.0mg and 0.5mg of melatonin versus placebo for poor sleep with randomization to 1 of 2 orders. The trial was comprised of a 2-week baseline period and a 12-week intervention period. The primary outcomes were #usability of the personalized trial system (measured using the System #usability Scale [SUS]) and participant satisfaction with the trial. Effectiveness outcomes included sleep duration (measured using a Fitbit activity tracker) and sleep quality (measured using the consensus sleep diary [CSD]). Results: Participants rated the #usability of the personalized trial as acceptable (average SUS score=76.3 [standard deviation (SD)=17.1]), and 96% (55/57) of those who completed satisfaction surveys stated that they would recommend the trial to others. Importantly, indices of HTE were low for 3.0mg and 0.5mg doses of melatonin, indicating that the effect of these treatments on sleep duration and sleep quality did not substantially vary between participants and that averaged treatment responses are appropriate. Averaged participant sleep duration did not significantly differ between the 3.0mg (P=0.7) and 0.5mg (P=0.9) melatonin intervention periods and the baseline period. Additionally, regression models did not show differences between different levels of melatonin and placebo periods for sleep duration or quality. Conclusions: Participant ratings of the #usability of and satisfaction with this series of personalized N-of-1 trials of melatonin for sleep suggest these trials are both feasible and acceptable. However, our results show that melatonin supplements did not significantly improve sleep duration or sleep quality. Further, the treatment effects’ lack of heterogeneity between participants suggests that future use of N-of-1 trials of melatonin for poor sleep is not needed.

JMIR Formative Res: A Series of Personalized Melatonin Supplement Interventions for Poor Sleep: #feasibility Randomized Crossover Trial for Personalized N-of-1 Treatment #Melatonin #SleepHealth #PersonalizedTreatment #Nof1Trials #SleepQuality

Exciting news! A new paper has been accepted in Behavior Therapy:

Congrats to @clarissaong.bsky.social, @claireecusack.bsky.social, and @cherilev.bsky.social on this important contribution!

#PersonalizedTreatment #NetworkTheory #EatingDisordersTreatment

#Transcriptomics identified four molecular subtypes of HR+/HER2+ #BreastCancer (BC), each exhibiting unique biological signatures, pathway activation patterns, & differential treatment responses, facilitating #PersonalizedTreatment.

#STTT #OpenAccess: doi.org/10.1038/s413...

Effects of the Intestinal Microbiome and Metabolites on Neoadjuvant Chemotherapy Efficacy in Breast Cancer Announcing a new article publication for BIO Integration journal. Imbalances in the intestinal microbiome are closely associated with the occurrence and development of cancer, and can affect tumorigen...

This study demonstrates significant differences in #intestinalflora structures and metabolite abundance between #chemotherapy-sensitive and #drugresistant patients, thereby offering potential #biomarkers for the formulation of #personalizedtreatment strategies.

bio-integration.org/intestinal-m...

A game-changing wireless implant for personalized chronic pain relief – BioNews Central A newly developed flexible, ultrasound-powered, wireless implantable stimulator is secured to the spine and designed for personalized, self-adaptive chronic pain management. ...

A newly developed flexible, #ultrasound - powered, #wireless implantable #stimulator is secured to the spine and designed for #personalized, self-adaptive #ChronicPainManagement.
#ChronicPain #SpinalCordStimulation #PersonalizedTreatment

NMR Spectroscopy: A New Era in Mood Disorder Research and Personalized Medicine

#NMR #MoodDisorders #Psychiatry #PrecisionMedicine #Neurochemistry #MentalHealthResearch #Neuroscience #PersonalizedTreatment #MentalHealthAwareness #Neuroimaging #FutureOfPsychiatry

youtube.com/shorts/JjaWu...

We should move away from traditional, often slow and one-size-fits-all methods towards more personalized, innovative, and adaptable strategies.

#Cancer #Kanser #CancerCare #CancerTreatment #PersonalizedTreatment #MedSky #PrecisionOncology

To fully realize the potential of precision medicine in cancer care, a fundamental shift is needed in how we approach research, treatment, and regulation.

Reference: www.nature.com/articles/s41...

#Cancer #Kanser #CancerCare #CancerTreatment #PersonalizedTreatment #MedSky #PrecisionOncology

The current status and future directions of artificial intelligence in the prediction, diagnosis, and treatment of liver diseases - Apr 13, 2025
@journals.sagepub.com

journals.sagepub.com/doi/10.1177/...

#AI #earlydetection #hepatology #personalizedtreatment #medsky #openaccess

Frontiers | Case report: Near-complete response to neratinib-based treatment in HR-positive HER2-amplified metastatic breast cancer refractory to trastuzumab deruxtecan

#Oncology #BreastCancer #PersonalizedTreatment

New artificial intelligence model personalizes bladder cancer treatment – BioNews Central A predictive model for chemotherapy response in muscle-invasive bladder cancer was developed by combining tumor imaging and gene expression data, potentially personalizing treatment and preventing unnecessary bladder removal. ...

A #PredictiveModel for #ChemotherapyResponse in muscle-invasive #BladderCancer was developed by combining #TumorImaging and #GeneExpression data, potentially personalizing treatment and preventing unnecessary #bladder removal.
#ArtificialIntelligence #PersonalizedTreatment

Dr. Eric Singhi now live, presenting Understanding Resistance to Targeted Therapy in Non-Small Cell Lung Cancer.

#TargetedTherapies #LungCancer #MolecularTesting #PersonalizedTreatment #NSCLC

Differentiating idiopathic Parkinson’s disease from multiple system atrophy-P using brain MRI-based radiomics: a multicenter study - Feb 26, 2025
@journals.sagepub.com

journals.sagepub.com/doi/10.1177/...

#diagnosis #diagnostics #neurology #personalizedtreatment #openaccess

Tryptophan metabolites profile predict remission with dietary therapy in pediatric Crohn’s disease - Feb 25, 2025
@journals.sagepub.com

journals.sagepub.com/doi/10.1177/...

#biomarker #gastroenterology #personalizedtreatment #openaccess

Why does addiction affect some people but not others? Brenna studies how experiences and genetics underlie addiction to help develop personalized treatments.
#addiction #addictiontreatments #neurosky #academicsky #personalizedtreatment #investinscience

Key point: Early onset genetic DEEs offer a valuable model to explore the neurobiological process underlying the epilepsy–autism phenotype.
doi.org/10.1111/epi....

#epilepsy #ILAE #autismspectrumdisorder #DEE #DEEassociatedgenes #personalizedtreatment

Future in Mental Health: How AI is Personalizing Treatment Plans Discover how AI is revolutionizing mental health care, enabling personalized treatment plans for improved outcomes and tailored patient support.

🌐 #AI is transforming mental health care! Discover how #ArtificialIntelligence is enabling #personalizedtreatment plans, improving early diagnosis, and revolutionizing #MentalHealth support.
🔗 www.knowledge-sourcing.com/resources/th...
#AIinhealthcare #healthcare #PersonalizedCare #MarketTrends

Scientists map cancer mutations in EGFR gene, revealing drug resistance paths Researchers used base and prime editing to uncover new EGFR gene mutations that affect cancer progression and drug resistance, paving the way for personalized treatment strategies.

Scientists map cancer mutations in EGFR gene, revealing drug resistance paths 🔬🧬🧪 www.news-medical.net/news/2024111... #Cancer #GeneEditing #EGFR #PrecisionMedicine #DrugResistance #CancerProgression #BaseEditing #PrimeEditing #PersonalizedTreatment @naturebiotech.bsky.social

How Important is Regular Blood Glucose Monitoring to You?


#bloodglucosemonitoring #bloodsugarlevels #diabetescare #DiabetesComplications #diabetesmanagement #diabetesmonitoringdevices #glycemiccontrol #Hyperglycemia #Hypoglycemia #personalizedtreatment
thediabeticwriter.com/?p=6633

AI model revolutionizes dementia diagnosis with high accuracy across multiple data sources Researchers developed an AI model using multimodal data to accurately diagnose different types of dementia, enhancing early and personalized treatment.

AI model revolutionizes dementia diagnosis with high accuracy across multiple data sources 🧠💡🔬 www.news-medical.net/news/2024070... #Dementia #AI #Healthcare #Neurology #CognitiveHealth #Alzheimers #MachineLearning #FutureMedicine #PersonalizedTreatment @natureportfolio.bsky.social

Watch Dr. Farrer’s presentation at the 21st Annual PD Symposium that took place on May 13th at https://www.youtube.com/watch?v=uwsUzE4bkvk&t=334s

#ParkinsonsResearch #GeneticsandHealth #FutureofMedicine #PersonalizedTreatment #Neuroscience

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