Scientists show #CyclicdiGMP inhibits #breastcancer #metastasis by binding #PSMD3, disrupting PSMD3–TBK1 interaction, and suppressing NF‑κB signaling, positioning PSMD3 as a therapeutic target. #Antimetastatic @tulanemedicine.bsky.social

#OpenAccess #STTT: doi.org/10.1038/s413...

#CyclicdiGMP suppresses #CancerMetastasis by directly targeting #PSMD3, disrupting its interaction with TBK1, and inhibiting NF‑κB signaling, thereby curbing metastatic #BreastCancer progression with minimal toxicity. @TulaneMedicine

#OpenAccess in #STTT: doi.org/10.1038/s413...