Unexpected cancer vulnerability points at potential novel treatments A novel way the immune system attacks target cells reshapes long-held assumptions in immunology and shows direct implications for the field of cancer immunology and bone marrow transplantation.

These findings have direct implications for the field of #cancer #immunology and #boneMarrowTransplantation. P. Reddy, A. Chinnaiyan, M. Cieslik et al #cancer #treatments. @bcmhouston.bsky.social #BCMCancerCenter @umich.edu #NatureImmunol blogs.bcm.edu/2026/03/31/f...

Research advances toward more effective, long-lasting and side effect-free cancer treatments The Baylor team is building the case for SRC-3 as a promising therapeutic target for next-generation cancer immunotherapy.

Drs. Sang Jun Han, D. Lonard et al are building the case for #SRC3 as a promising #therapeuticTarget for next-generation #cancer #immunotherapy. #Oncoimmunology @tandfonline.bsky.social @bcmhouston.bsky.social #BCMCancerCenter #HotTumor #ColdTumor blogs.bcm.edu/2026/03/26/f...

ZR fusion protein sways normal brain cell development toward cancer growth A team of researchers at Baylor College of Medicine, St. Jude Children’s Research Hospital, Texas Children’s Hospital and collaborating institutions...

Team at @bcmhouston.bsky.social, @stjuderesearch.bsky.social et al reveals driver of the third most common pediatric #brainTumor. #ependymoma B Deneen, @alishakardian.bsky.social S. Mack @bcmneurosurgery.bsky.social #BCMGradSchool #BCMCancerCenter #TexasChildrens www.bcm.edu/news/zr-fusi...

Unrecognized Immune Mechanism Uncovered: New Insights Could Transform Defense Against Cancer - Onco'Zine Unrecognized Immune Mechanism Uncovered: New Insights Could Transform Defense Against Cancer

Drs. P. Reddy, A. Chinnaiyan, M. Cieslik et al's discovery offers the possibility of novel, more effective #cancer #treatments. @bcmhouston.bsky.social #BCMCancerCenter @umich.edu #NatureImmunol www.oncozine.com/unrecognized...

There is more than one way for triple-negative breast cancer to become resistant to therapy About 50% of triple-negative breast cancer (TNBC) patients develop resistance to therapy. When resistance arises, tumors are more likely to come back after...

X. Zhang Lab, L Yu et al discovered different ways for #tripleNegativeBreastCancer to become #resistant to #therapy. @jci.org @bcmhouston.bsky.social #BCMCancerCenter www.bcm.edu/news/there-i...

Breast cancer cell clusters The Image this month shows a mechanism that mediates the formation of breast cancer cell clusters and promotes cancer metastasis.

Check out #FromtheLabs' new Image of the Month! Image courtesy of the C. Cheng lab. @bcmhouston.bsky.social @bcmgenetics.bsky.social #TripleNegativeBreastCancer #Metastasis #BCMCancerCenter #BCMpostdoc blogs.bcm.edu/2026/02/26/f...

‘Sticky coat’ boosts triple negative #breastCancer’s ability to metastasize www.eurekalert.org/news-release... #CChengLab, G Bobkov, K Patel et al @natcomms.nature.com @bcmhouston.bsky.social @bcmgenetics.bsky.social #BCMCancerCenter #BCMpostdoc #Cellclusters

Breakthrough enables continuous laboratory growth of human norovirus Researchers at Baylor College of Medicine report in Science Advances a breakthrough in human norovirus (HuNoV) research.

#Breakthrough at #EstesLab et al enables continuous laboratory growth of #humanNorovirus. @bcmhouston.bsky.social #HumanIntestinalEnteroids #ScienceAdvances @tmcddc.bsky.social #BCMCancerCenter #BCMGradSchool www.news-medical.net/news/2026020...

Breakthrough in human norovirus research: scientists overcome major obstacle to grow and study the virus Growing and maintaining norovirus strains in the lab allows researchers to advance studies of viral structure, antiviral drug screening and vaccine development.

#EstesLab_BCM et al have achieved a #breakthrough on #HumanNorovirus #research, accelerating viral, vaccine and treatment studies. #HumanIntestinalEnteroids #ScienceAdvances @science.org @bcmhouston.bsky.social @tmcddc.bsky.social #BCMCancerCenter #BCMGradSchool blogs.bcm.edu/2026/02/05/f...

Anti-CSF-1R therapy with combined immuno-chemotherapy coordinate an adaptive immune response to eliminate macrophage enriched triple negative breast cancers - Nature Communications Metastatic triple negative breast cancer (mTNBC) has limited treatments options. Here, this group presents a combination of low-dose cyclophosphamide, anti-CSF1R, and anti-PD-1 therapies to boost immu...

Interested in novel therapies for #TripleNegative #BreastCancer? Drs. D. Pedroza, J Rosen et al have promising new findings. #AntiCSF1R #Immunochemotherapy @natcomms.nature.com #BCMCancerCenter @bcmhouston.bsky.social www.nature.com/articles/s41...

New cell markers to track the most aggressive breast cancer in blood Tumor cells that were frequently undetectable using standard markers became clearly visible when the team applied the new marker combination.

C. Cheng et al have found a way to track the most aggressive #BreastCancer in blood. #TNBC @theaacr.bsky.social @bcmhouston.bsky.social @bcmgenetics.bsky.social #BCMCancerCenter blogs.bcm.edu/2026/01/29/f...

Pancreatic cancer research breakthrough ABC News' Becky Worley is in Houston, Texas, where a medical college is on the frontlines in the fight against pancreatic cancer.

#PancreaticCancer research #breakthrough. See the patient story of the work by B. Musher, AM Leen et al in Good Morning America. @bcmhouston.bsky.social @naturemedicine.bsky.social #CAGTHouston #BCMCancerCenter www.goodmorningamerica.com/video/129449...

Finding new cell markers to track the most aggressive breast cancer in blood Of all the types of breast cancer, triple negative breast cancer (TNBC) is the most aggressive and lacks specific therapies. TNBC also is more likely to...

Finding new cell markers to #track the most #aggressive #BreastCancer in blood #CChengLab et al #CRC_AACR @bcmhouston.bsky.social @bcmgenetics.bsky.social #BCMCancerCenter www.bcm.edu/news/finding...

CPRIT awards more than $15 million to BCM for cancer research Researchers at the Dan L Duncan Comprehensive Cancer Center at Baylor College of Medicine have been awarded more than $15 million in grants by the Cancer...

#CPRIT awards more than $15 million to BCM @bcmhouston.bsky.social for #CancerResearch #BCMCancerCenter www.bcm.edu/news/cprit-a...

Brain “stars” hold the power to preserve cognitive function in model of Alzheimer’s disease Researchers at Baylor College of Medicine have discovered a natural mechanism that clears existing amyloid plaques in the brains of mouse models of Alzheimer’s...

Brain “stars” hold the power to preserve #cognitiveFunction in model of #AlzheimersDisease. DJ Choi @uthealthhouston.bsky.social, B. Deneen @bcmhouston.bsky.social et al @bcmneurosurgery.bsky.social #BCMCancerCenter #TCHResearchNews @natneuro.nature.com #astrocytes www.bcm.edu/news/brain-s...

p53 mutant R273H opens new avenues for future personalized cancer treatment This study highlights the importance of understanding the specific type of p53 mutation in each patient’s tumor, as it may influence both disease behavior and therapeutic strategies.

A mutant of #p53, the 'guardian of the #genome', opens new possibilities for future personalized #cancer treatment. WC Lin @bcmhouston.bsky.social #BCMCancerCenter @commsbio.nature.com blogs.bcm.edu/2025/11/11/f...

Immunotherapy for pancreatic cancer shows promise Clinical trials with T-cell therapy for pancreatic cancer show clinical responses with no serious side effects.

#Immunotherapy for #PancreaticCancer shows promise. blogs.bcm.edu/2019/07/23/f... #pancreaticCancerAwarenessMonth @bcmhouston.bsky.social #BCMCancerCenter

Some p53 mutations could help fight cancer Researchers at Baylor College of Medicine have discovered that certain p53 mutants hijack the DNA replication machinery causing it to fire excessively,...

Dr. Weei-Chin Lin et at identified #p53 mutations that could help fight #cancer @bcmhouston.bsky.social #BCMDeptMedicine #BCMCancerCenter @commsbio.nature.com www.bcm.edu/news/some-p5...

Hispanic Heritage Spotlight: Interview with Dr. Nino Rainusso Dr. Rainusso shared his experience finding a research position in a Baylor lab and something few know about him.

Dr. Nino Rainusso studies #pediatricCancer. Read on to learn what motivated him to pursue this research path. @bcmhouston.bsky.social #BCMCancerCenter #HispanicHeritageMonth blogs.bcm.edu/2020/11/12/f...

Becoming metastatic: how FOXA1 triggers metastatic behavior in breast cancer This is how hyperactive FOXA1 triggers enhanced resistance to treatment and metastatic behaviors in ER-positive breast cancer.

Research shows how #breastCancerCells acquire #metastatic behavior @bcmhouston.bsky.social @pnas.org #BCMDeptMedicine #BCMCancerCenter #MetastaticBreastCancerAwarenessDay blogs.bcm.edu/2020/01/16/f...

Dr. Graham Erwin @grahamerwin.bsky.social receives NIH New Innovator Award! www.bcm.edu/news/dr-grah... @bcmhouston.bsky.social @bcmgenetics.bsky.social #BCMCancerCenter

Breast cancer clues hint at response to therapy in animal models The findings bring us one step closer to improving ER+ breast cancer patients’ response to therapy.

Some #breastCancers provide clues indicating whether they are susceptible to #therapy, helping inform treatment decisions. E Chang et al. #ScienceTM @bcmhouston.bsky.social #BCMCancerCenter blogs.bcm.edu/2025/09/18/f...

Exercise helps improve #memory in #AlzheimersDisease -- Baylor researchers discovered how. @bcmhouston.bsky.social #BCMDeptMedicine #BCMCancerCenter #AlzheimersandDementia #amyliod #EGFR #insulin #Hippocampus blogs.bcm.edu/2025/09/16/f...

AI connects mutations, protein modifications and disease The new AI tool, called DeepMVP, significantly outperforms previously published models and has implications for the development of novel therapeutics.

#DeepMVP improves the ability to predict gene #mutations that may lead to #disease. B. Zhang, C. Wang et al #naturemethods @bcmgenetics.bsky.social @bcmhouston.bsky.social #BCMCancerCenter blogs.bcm.edu/2025/09/09/f...

It's not only genes, gene-diet interactions also regulate circadian rhythms The findings show that diet interacts with an individual’s genetic makeup, influencing daily patterns of gene activity in the liver, especially those related to fat metabolism.

Research suggests that individual genetic makeup could influence not just how the body handles fat, but when it does so. @dongyinguan.bsky.social, Y Chen, D Zhou et al. @cp-cellmetabolism.bsky.social @bcmhouston.bsky.social #BCMDeptMedicine #BCMCancerCenter #BCMPostdoc blogs.bcm.edu/2025/09/02/f...

One step closer to improving ER+ breast cancer patients’ response to therapy A new study from researchers at Baylor College of Medicine brings hope for a more personalized approach to treat estrogen receptor-positive (ER+) breast...

Study brings us one step closer to improving ER+ #breastCancer patients’ response to therapy. E. Chang et al. #BreastCenter @bcmhouston.bsky.social #BCMCancerCenter #ScienceTranslMed www.bcm.edu/news/one-ste...

AI reveals how protein modifications link mutations to disease Researchers at Baylor College of Medicine have developed an artificial intelligence (AI) model that reveals how protein modifications link genetic mutations...

Researchers at @bcmhouston.bsky.social have developed an #AI model that reveals how protein modifications link genetic #mutations to #disease. B Zhang, C Wang, B Wen, K Li et al. @natmethods.nature.com @bcmgenetics.bsky.social #BCMCancerCenter www.bcm.edu/news/ai-reve...

Gene-diet interactions help regulate the body’s daily rhythms Our bodies follow a natural 24-hour cycle known as the circadian rhythm that influences everything from sleep to metabolism. While scientists have long...

Dr. @dongyinguan.bsky.social, Y Chen et al found that #diet interacts with an individual’s genetic makeup, influencing daily patterns of gene activity. #CircadianRhythm @cp-cellmetabolism.bsky.social #Chronotherapy #BCMDeptMedicine #BCMCancerCenter @bcmhouston.bsky.social www.bcm.edu/news/gene-di...

Understanding what makes some bladder cancers resistant to chemotherapy About one quarter of patients with muscle-invasive bladder cancer (MIBC) may be treated and derive a benefit with the current standard chemotherapy. To...

Drs. S Lerner, M Holt, Y Dou et al found markers in muscle-invasive #bladderCancer tumors that would help predict which patients were most likely to benefit from #chemotherapy. #bcm_urology @bcmhouston.bsky.social #BCMCancerCenter @cp-cellrepmed.bsky.social www.bcm.edu/news/underst...

Proteogenomic characterization unveils biomarkers associated with chemoresistance in muscle-invasive bladder cancer Holt et al. perform proteogenomic characterization of 46 pre- and 14 post-treatment muscle-invasive bladder tumors. Multi-omics clustering separates chemotherapy-sensitive and -resistant tumors. In-de...

Drs. S. Lerner, M Holt, Y Dou et al made strides toward a better understanding of what makes some #bladderCancers resistant to #chemotherapy. #bcm_urology @bcmhouston.bsky.social #BCMCancerCenter @cp-cellrepmed.bsky.social cell.com/cell-reports...