Testosterone promotes growth of a type of brain tumour in young boys A type of childhood brain tumour called ependymoma is more common in boys than in girls. The reason for this difference turns out to be sex hormones such as testosterone.

News & Views article comments on M Taylor, J. Zhang, @claudiakleinman.bsky.social, K.A. Michealraj et al paper about a pediatric #BrainTumor affecting more boys than girls. @bcmhouston.bsky.social, #TexasChildrens, @mcgill.ca @pittdeptofmed.bsky.social @nature.com www.nature.com/articles/d41...

ZR fusion protein sways normal brain cell development toward cancer growth A team of researchers at Baylor College of Medicine, St. Jude Children’s Research Hospital, Texas Children’s Hospital and collaborating institutions...

Team at @bcmhouston.bsky.social, @stjuderesearch.bsky.social et al reveals driver of the third most common pediatric #brainTumor. #ependymoma B Deneen, @alishakardian.bsky.social S. Mack @bcmneurosurgery.bsky.social #BCMGradSchool #BCMCancerCenter #TexasChildrens www.bcm.edu/news/zr-fusi...

Researchers uncovered the driving force behind lethal infant brain tumor An international team led by researchers at Baylor College of Medicine, Texas Children’s Hospital, McGill University and University of Pittsburgh School...

A team at @bcmhouston.bsky.social, #TexasChildrens, @mcgilluniversity.bsky.social @pittdeptofmed.bsky.social et al explains why a lethal pediatric #Brain tumor affects more boys than girls. @nature.com M Taylor, J. Zhang, @claudiakleinman.bsky.social, K.A. Michealraj www.bcm.edu/news/researc...

Dr. Ryan S. Dhindsa @ryandhindsa.bsky.social has been awarded the American Brain Foundation’s @abfbrain.bsky.social Cure One, Cure Many #grant to advance new ways to prevent and treat #AlzheimersDisease. @bcmhouston.bsky.social #TexasChildrens www.bcm.edu/news/bcm-res...

Experimental hookworm vaccine shows promising protection in phase 2 human trial Hookworm infects an estimated 113 million people globally primarily in sub-Saharan Africa, Southeast Asia, and South America. It is a major cause of iron-deficiency anemia in children and pregnant wom...

D. Diemert #gwsmhs, @peterhotezmdphd.bsky.social, @mebottazzi.bsky.social, @bcmhouston.bsky.social #TexasChildrens et al found experimental #hookworm #vaccine shows promising #protection in phase 2 human trial
@thelancetinfdis.bsky.social blogs.bcm.edu/2026/03/19/f...

Glutamatergic projection neurons in the basal forebrain underlie learned olfactory associational valence assignments - Nature Communications Neural mechanisms underlying motivation-driven behaviors are not fully understood. Here authors show that non-cholinergic neurons in rodent basal forebrain link sensory stimuli with motivational state...

Ben Arenkiel’s recent @NatureComms paper has been featured in the Editor’s highlights. #GlutamatergicNeuron #senseofSmell @bcmhouston.bsky.social @natcomms.nature.com #TexasChildrens www.nature.com/articles/s41...

A promising potential therapeutic strategy for Rett syndrome A team of researchers at Baylor College of Medicine and the Duncan Neurological Research Institute (Duncan NRI) at Texas Children’s Hospital reports...

The H Zoghbi lab et al provide evidence for new approach to treat #RettSyndrome. @bcmhouston.bsky.social #TexasChildrens @bcmgenetics.bsky.social s.bsky.social @rsrt.bsky.social www.bcm.edu/news/a-promi...

Interested in metabolic ‘mimickers’ of #rheumatologicalDisease? L. Burrage, T. Vogel et al have a new review on the topic. @natrevrheum.nature.com @bcmhouston.bsky.social @bcmgenetics.bsky.social #TexasChildrens www.nature.com/articles/s41...

Connecting the dots between cause-effect events in Alzheimer’s disease This cross-species approach reveals that some paths seem to aggravate the disease while others may protect against it.

This study reveals that some molecular paths linked to #Alzheimers seem to aggravate the disease while others may protect against it. J Shulman et al @bcmhouston.bsky.social #TexasChildrens @bcmneurosci.bsky.social @bcmgenetics.bsky.social blogs.bcm.edu/2026/02/24/f...

Researchers connect the dots between cause-effect events in Alzheimer’s disease A study published in Molecular Psychiatry reveals a path of cause-effect molecular...

Researchers look to better understand how typical #Alzheimer’s brain changes, such as the formation of amyloid plaques and tau tangles, can lead to #neurodegeneration and #cognitiveDecline. #LabShulman @bcmhouston.bsky.social @bcmgenetics.bsky.social #TexasChildrens www.bcm.edu/news/researc...

Dr. S. Yamamoto recognized with International Honor for Groundbreaking #RareDisease Discovery. @bcmhouston.bsky.social @bcmgenetics.bsky.social #TexasChildrens #NISTEP texaschildrens.org/content/news...

Partners in crime – genes ATP13A2 and GBA1 interact to drive neurodegeneration The findings reveal promising biological pathways that could be explored in future therapies.

Why some people with #geneticRisk factors develop #ParkinsonsDisease while others never do? M Gu, H Bellen et al have found an explanation. @bcmhouston.bsky.social @bcmgenetics.bsky.social #TexasChildrens @molneurodegen.bsky.social #BCMPostDoc blogs.bcm.edu/2026/02/12/f...

From lab bench to bedside – research in mice leads to answers for undiagnosed human neurodevelopmental conditions The findings have provided answers to families that until now had no diagnosis for their child's condition.

Years of research with animal models led to answers to families with a child with undiagnosed conditions. D. Calame and @jesse-levine.bsky.social. blogs.bcm.edu/2026/02/10/f... @bcmhouston.bsky.social @gregor-research.bsky.social @ajhgnews.bsky.social #HumanGenetics #TexasChildrens

Researchers #LabShulman et al uncovered how #SPTSSB gene variant triggers a process that can lead to #ParkinsonsDisease. #lipids @bcmhouston.bsky.social #TexasChildrens #BrainJournal @oxunipress.bsky.social @bcmgenetics.bsky.social @bcmneurosci.bsky.social medicalxpress.com/news/2026-02...

Genetic Duo: ATP13A2 and GBA1 Interactions Fuel Neurodegeneration Parkinson’s disease (PD) ranks as the second most prevalent neurodegenerative disorder following Alzheimer’s disease, impacting more than 10 million individuals globally. The condition manifests thr

Genetic Duo: #ATP13A2 and #GBA1 Interactions Fuel #Neurodegeneration. M. Gu and H Bellen explain their findings. @bcmhouston.bsky.social #TexasChildrens
@molneurodegen.bsky.social @bcmgenetics.bsky.social #BCMPostDoc bioengineer.org/genetic-duo-...

It takes two: Genes ATP13A2 and GBA1 interact to drive neurodegeneration Parkinson's disease (PD) is the second most common neurodegenerative disease after Alzheimer's disease, affecting more than 10 million people worldwide. People with this condition may experience tremo...

How do two altered genes, #ATP13A2 and #GBA1, in two different cell types lead to neurodegeneration? M. Gu and H Bellen explain their findings. @bcmhouston.bsky.social #TexasChildrens @molneurodegen.bsky.social @bcmgenetics.bsky.social #BCMPostDoc medicalxpress.com/news/2026-02...

DNA research uncovers 22 genes that could put people at risk of long-term health conditions following common viral infection Baylor College of Medicine researchers are part of a collaborative research group with AstraZeneca and Memorial Sloan Kettering Cancer Center that have...

Baylor College of Medicine @bcmhouston.bsky.social, @astra-zeneca.bsky.social, @mskcancercenter.bsky.social identified genes that increase the risk of developing chronic conditions after #viralInfection. #EBV @nature.com @ryandhindsa.bsky.social #DuncanNRI #TexasChildrens www.bcm.edu/news/dna-res...

How too much of a good thing leads to neurodegenerative disease This study opens the door to new strategies for potentially slowing or preventing VCP-linked neurodegeneration.

How can too much of a good thing lead to #neurodegenerativeDiseases? Dr. T Lloyd and colleagues have answers. @cp-neuron.bsky.social @bcmhouston.bsky.social #bcmneurology #TexasChildrens blogs.bcm.edu/2026/01/27/f...

Are you interested in the link between #polyglutamine and #neurodegeneration? E. Villavicencio & H. Zoghbi have just published a #review about it. @jem.org @bcmhouston.bsky.social #TexasChildrens @bcmgenetics.bsky.social @bcmneurosci.bsky.social rupress.org/jem/article/...

Texas Children's/Baylor College of Medicine Researchers Create Groundbreaking Tool to Improve Accuracy of #GeneticTesting @egatkinson.bsky.social @bcmgenetics.bsky.social @bcmhouston.bsky.social #TCHResearchNews #TexasChildrens @natcomms.nature.com tinyurl.com/jj6kyrrv

Heterogeneity of Diabetes - NIDDK This Report outlines research Recommendations from the NIDDK’s Working Group of Council on Heterogeneity of Diabetes.

The Working Group of the #NIDDKgov published a strategic plan and report on heterogeneity of #diabetes and recommendations. Dr. M J Redondo at @bcmhouston.bsky.social is a member of the working group. #BCMDeptMedicine #pediatrics #TexasChildrens www.niddk.nih.gov/about-niddk/...

September is #ChildhoodCancerAwarenessMonth. Check the research by T. Werbowetski-Ogilvie Tamra et al showing how #geneSplicing gone wrong leads to aggressive #BrainTumor. #BCM_Pediatrics @bcmhouston.bsky.social #TexasChildrens blogs.bcm.edu/2024/08/27/f...

Technical Advances and Outcomes of Fetal Atrial Septal Intervention for Restrictive or Intact Atrial Septum | Circulation: Cardiovascular Interventions BACKGROUND: Infants with hypoplastic left heart syndrome with severely restrictive or intact atrial septum (R/IAS) have low survival. In-utero creation of an atrial septal communication has been repor...

Novel surgical procedure increases positive outcomes in infants with serious heart condition. @bcmhouston.bsky.social #TexasChildrens www.ahajournals.org/doi/10.1161/...

Long non-coding RNAs reveal an unexpected way to regulate gene expression Long non-coding RNAs (lncRNA) are a type of RNA molecule that do not carry instructions to make proteins. Instead, they influence how other genes are expressed. There are tens of thousands of lncRNAs ...

P. Sumazin, H-S Chiu, S. Somvanshi et al discovered an unexpected way long noncoding #RNA regulates #geneExpression. #cancer #BigHorn @bcmhouston.bsky.social #TexasChildrens #CellGenomics @rnasociety.bsky.social phys.org/news/2025-08...

Image of the Month: A closer look at metastatic medulloblastoma The image captures metastatic medulloblastoma tumor cells (green) intertwined with blood vessels (magenta) in the leptomeninges of a mouse model of the human condition.

Check out our image this month; take a closer look at #metastaticmedulloblastoma #MichaelTaylorLab @bcmhouston.bsky.social #TexasChildrens #BCMCancerCenter @bcmneurosurgery.bsky.social #brainTumor blogs.bcm.edu/2025/05/06/f...

Traditional blood-filtering treatments for #children with #leukemia come with serious risks. A team from University of Houston @uh.edu and Baylor College of Medicine @bcmhouston.bsky.social has developed a safer alternative. #NatureComms #TexasChildrens stories.uh.edu/2025-childho...

So honored to present our work on brain volume loss in pediatric MS patients at the ASPNR 2025 Annual Conference! #BCMChildNeuro #TexasChildrens #neuroradiology #multiplesclerosis