Current Status and Advances in Anti-Androgen Therapy for Triple-Negative Breast Cancer

This article systematically reviews #Androgen #TargetedTherapy for #TripleNegativeBreastCancer, incorporating recent advances and charting future directions in both research and #clinical practice. #medsky

Full article here: doi.org/10.1007/s115...

New evidence that high-fat diets promote tumor growth in aggressive breast cancer – BioNews Central Researchers have revealed new links between high-fat diets and aggressive breast cancer, demonstrating the important role fat plays in making some cancers more invasive. ...

Researchers have revealed new links between #HighFatDiets and #AggressiveBreastCancer, demonstrating the important role #fat plays in making some #cancers more invasive. 
#BreastCancer #TripleNegativeBreastCancer

Researchers from the Breast Cancer Now research units have found that the incorrect activation of the HORMAD1 gene may drive genetic instability in aggressive breast cancers.

Read more for FREE in BioNews ⬇️
progress.org.uk/potential-ne...

#TripleNegativeBreastCancer #BreastCancer

Mechanisms driving TNBC treatment resistance identified Researchers have uncovered two mutually exclusive mechanisms that can give TNBC the ability to survive therapy.

A study by X Zhang lab, L Yu et al points at a novel approach to improve treatment outcomes in #tripleNegativeBreastCancer. www.oncology-central.com/mechanisms-d... @bcmhouston.bsky.social @jci.org #breastCancer

Early results for a potential #TripleNegativeBreastCancer vaccine are encouraging. 74% of participants triggered the immune response needed for the vaccine to work.

Here’s what it could mean for people at higher genetic or recurrence risk for #TNBC:
https://bit.ly/3YnJFbV

#TNBCDay

Join us tomorrow at 1 PM ET to connect with others who share the unique experiences of navigating life with metastatic TNBC.

📆 First Wednesday of every month, 1 PM ET

Register for this month's meetup here: https://bit.ly/TNBC_MBC

#TNBCDay #TNBC #TripleNegativeBreastCancer #TNBCThriver

#TNBC accounts for about 10–15% of breast cancers and nearly 20% of those diagnosed in Black women.

This #TNBCDay, help raise awareness, share support, and spread hope for those navigating a diagnosis.

Explore resources here: https://bit.ly/TNBCawareness

#TripleNegativeBreastCancer

Illustration of three pink ribbons with text: “Triple-negative breast cancer* can be a hereditary cancer red flag! * Breast cancer with no estrogen, progesterone, or HER2 receptors on the tumor. Learn more at www.genetionary.org.”

Inherited mutations in BARD1, BRCA1, BRCA2, PALB2, and RAD51D genes are linked to an increased risk for TNBC.

Learn more at www.genetionary.org
For more info please talk to your doctor and/or a certified genetic counselor.

#triplenegativebreastcancer #hereditarycancer #TNBC #genes #BRCA1 #BRCA2

Daiichi Sankyo gears up for five ADC launches in 2026

#DaiichiSankyo #ADCs #ADClaunches #Enhertu #Datroway #breastcancer #Oncology #antibodydrugconjugates #trastuzumabderuxtecan #datopotamabderuxtecan #pertuzumab #earlystagebreastcancer #triplenegativebreastcancer #Ifinatamabderuxtecan #IDXd #TROPIONBreast05study #ADCtechnology
zurl.co/TySHW

There is more than one way for triple-negative breast cancer to become resistant to therapy About 50% of triple-negative breast cancer (TNBC) patients develop resistance to therapy. When resistance arises, tumors are more likely to come back after...

X. Zhang Lab, L Yu et al discovered different ways for #tripleNegativeBreastCancer to become #resistant to #therapy. @jci.org @bcmhouston.bsky.social #BCMCancerCenter www.bcm.edu/news/there-i...

Breast cancer cell clusters The Image this month shows a mechanism that mediates the formation of breast cancer cell clusters and promotes cancer metastasis.

Check out #FromtheLabs' new Image of the Month! Image courtesy of the C. Cheng lab. @bcmhouston.bsky.social @bcmgenetics.bsky.social #TripleNegativeBreastCancer #Metastasis #BCMCancerCenter #BCMpostdoc blogs.bcm.edu/2026/02/26/f...

‘Sticky coat’ boosts triple negative breast cancer’s ability to metastasize Researchers at Baylor College of Medicine have uncovered a strategy that triple negative breast cancer (TNBC) cells use to boost their ability to metastasize,...

Researchers have uncovered a strategy that triple negative breast cancer cells use to boost their ability to metastasize or spread to other organs. #BCMResearch #TripleNegativeBreastCancer

In this paper, Ji et al. report a biomimetic nanodelivery system (OPTC-RNP@CM) based on near-infrared photoregulation semiconductor polymers (OPT) that effectively inhibits TNBC tumor growth.
doi.org/10.59717/j.x...
#materials #triplenegativebreastcancer #drugdelivery

ErVimmune raises 17m euros in funding to develop cancer vaccine - PharmaTimes The vaccine could be created as a ready-to-use product, rather than needing to be personalised

#vaccinedevelopment #ErVimmune #biotech #cancervaccine #readytousevaccine #personalisedvaccines #celltherapies #cancervaccines #cancervaccinecandidate #ErVac01 #immunotherapies #coldtumours #triplenegativebreastcancer #ovariancancer #offtheshelfcancervaccine #difficulttotreatcancers
zurl.co/Z94ou

Cholesterol-lowering drug can overcome chemotherapy resistance in triple-negative breast cancer – BioNews Central Pitavastatin, a common cholesterol-lowering drug, counteracts chemotherapy resistance in triple-negative breast cancer cells by directly blocking the anti-apoptotic protein Mcl-1. ...

#Pitavastatin, a common #CholesterolLoweringDrug, counteracts #ChemotherapyResistance in #TripleNegativeBreastCancer cells by directly blocking the anti-apoptotic protein Mcl-1.
#Statins #BreastCancer #BreastCancerTreatment

Cytotoxic Effects of Mono- and Trinuclear Platinum(II)-N-Heterocyclic Carbene Complexes against Triple-Negative Breast Cancer Cell Lines.
Chowdhury, Soujannya et al.
Paper
Details
#PlatinumChemistry #TripleNegativeBreastCancer #HeterocyclicCarbene

New drug developed for aggressive breast cancer – BioNews Central A newly developed molecule offers a promising approach to treating intractable cases of triple-negative breast cancer — a form of cancer that is notoriously aggressive and lacks effective treatments. ...

A newly developed molecule offers a promising approach to treating intractable cases of #TripleNegativeBreastCancer — a form of cancer that is notoriously aggressive and lacks effective treatments.
#BreastCancer #BreastCancerDrug 

China NMPA Approves Secituzumab Tirumotecan for Injection

📩 info@dengyuemed.com
🔗https://dengyuemed.com

#ChinaNMPA #DrugApproval #SecituzumabTirumotecan #ADC #TROP2 #TripleNegativeBreastCancer #KelunBiotech #Jiatailai

Major advances in treatment and care have led to improved survival for many women with advanced breast cancer, new study finds.

youtu.be/nJWKKsdFvYw

#MetastaticBreastCancer #AdvancedBreastCancer #BreastCancerSurvival #HER2Positive #HormoneReceptorPositive #TripleNegativeBreastCancer

#TeamReSynBio would like to show solidarity and promote awareness for #MetastaticBreastCancerAwareness. We would especially like to thank our collaborators in #TripleNegativeBreastCancer research, CSIR and University of Pretoria on #WorldMBCAwarenessDay!

Living Near Toxic Sites Linked to Aggressive Breast Cancer | Newswise Women living close to federally designated Superfund sites are more likely to develop aggressive breast cancers — including the hard-to-treat triple-negative subtype — according to new studies from Sy...

Living Near Toxic Sites Linked to Aggressive Breast Cancer
www.newswise.com/articles/liv...
#superfundsites #superfund #breastcancer #triplenegativebreastcancer

Delayed TNBC readout for Datroway delivers survival benefit AstraZeneca and Daiichi Sankyo's Datroway comes good in the delayed TROPION-Breast02 trial as a frontline triple-negative breast cancer treatment.

#breastcancer #triplenegativebreastcancer #TNBC #AstraZeneca #AZ #Datroway #datopotamabderuxtecan #DaiichiSankyo #Oncology #TNBCpatients #TROPIONBreast02trial #metastaticTNBC #immunotherapy #TNBCtumours #Gilead #TROP2ADC #Trodelvy #sacituzumabgovitecan #PFSdata
zurl.co/t8A6T

Restoring order to dividing breast cancer cells may prevent metastasis – BioNews Central The enzyme EZH2 drives abnormal division in triple-negative breast cancer cells, and drugs that inhibit EZH2 can restore normal cell division and prevent metastasis. ...

The enzyme #EZH2 drives abnormal division in #TripleNegativeBreastCancer cells, and drugs that inhibit EZH2 can restore normal #CellDivision and prevent #metastasis.
#BreastCancer #Epigenetics

This study reveals that #FattyAcidSynthase inhibition via PPIs enhances poly (ADP-ribose) polymerase inhibitor (PARPi) efficacy in #TripleNegativeBreastCancer (TNBC), offering a strategy to combat PARPi resistance in #TNBC. #medsky
#OpenAccess:
www.sciencedirect.com/science/arti...

💪 #TripleNegativeBreastCancer ➡️ Exciting progress on pancreatic cancer too! A new genetic panel (patent pending!) incorporates both global & 🇮🇳-specific mutations. Plus, they're searching for biomarkers detectable in blood for non-invasive early detection!

Triple-Negative Breast Cancer: Molecular Subtypes, Therapeutic Challenges, and Emerging Strategies—A Systematic Review - Premier Science Triple-Negative Breast Cancer molecular subtyping, Parp inhibitor therapy, Immune checkpoint blockade, Platinum-based chemotherapy.

doi.org/10.70389/PJS...

#triplenegativebreastcancer #breastcancer

Congratulations to Fatemeh Alimohammadi, doctoral candidate at the University of Rochester for being awarded The Pamela Delp Polashenski M.D. Breast Cancer Research Trainee Grant in the amount of $25,000. bccr.org/research/
#researchmatters #breastcancerresearch #triplenegativebreastcancer

Ajay Dhakal, MD, at Wilmot Cancer Institute, has been awarded the Sylvia Cappellino Breast Cancer Research Faculty Grant in the amount of $50,000 for “Factors Associated with CNS Recurrence of Primary Triple Negative Breast Cancer.”
bccr.org/research/
#researchmatters #triplenegativebreastcancer

The purpose of the #ASPRIA trial is to determine if a combination of two drugs, #Atezolizumab and #SacituzumabGovitecan, can be used to prevent recurrence in #TripleNegativeBreastCancer.
For more information call 877-338-7425 or visit:
www.dana-farber.org/clinical-tri...
#BreastCancer #TNBC

Honored to speak at @clevelandclinic.bsky.social 9th Annual Breast Cancer Summit on disparities in #TripleNegativeBreastCancer. #TNBC is a complex subtype of cancer affecting ~10–15% of patients. Grateful we’re shining a light on this critical issue. #BreastCancerAwareness @jameabraham.bsky.social