Very excited to share our preprint showing S-acylation (aka Palmitoylation) of TDP-43, VCP, SQSTM1, FUS & C9Orf72 in Huntington Disease (HD), Amyotrophic Lateral Sclerosis (ALS), & Multisystem Proteinopathy (MSP). This tour de force was led by @firyalrphd.bsky.social!
www.biorxiv.org/content/10.6...
#JNeurosci Review | Perry and Martin discuss the links between ALS and Huntington Disease, highlighting two proteins that potentially contribute to the onset and progression of these neurodegenerative diseases.
https://doi.org/10.1523/JNEUROSCI.0263-25.2026
Screenshot from the JNeursci Webpage showing the cover art. This artwork portrays a fictional person with amyotrophic lateral sclerosis (ALS). Framing their face is a network of neurons that highlights two motor neurons. One neuron extending from the mouth down to the hands symbolizes two of the major motor functions affected by ALS: bulbar and spinal. The second neuron forms from a single tear that represents the fear those with the disease endure. As this neuron extends to the hands, the connection is severed, symbolizing both the disconnect between the brain and muscles caused by neuron death and the determination of those affected not to be defined by their disease. The bound hands emphasize the physical constraints imposed by ALS while the distance between the hands conveys perseverance. Among the wildflowers shown is the blue cornflower, an emblematic symbol of ALS representing hope and resilience. See the review article by Cailyn Perry and Dale Martin for information on mechanistic links between ALS and Huntington's disease. Cover image: Cailyn Perry.
Thrilled to share our recent review in @sfnjournals.bsky.social ALS and Huntington Disease: Unraveling the Connections between TDP-43 and Huntingtin. Here we discuss links between HD & ALS. Review & cover art come from the multitalented MSc student @cailyncreative.bsky.social
tinyurl.com/57y6hjrd
If you want to see our research promoted like it's a sports event go to the 1h13min mark: www.upliftingathletes.org/young-invest...
It was really cool to hear our work described this way.
Save the Date for the next @csmb-scbm.bsky.social meeting:
Membrane Proteins in Health & Diseases
April 8-12, 2026 in beautiful Banff!
Looks like there's something for everyone.
event.fourwaves.com/2026csmb/pages
A blue poster describing opportunities to join the Bernhardt Lab -- for more information please see https://www.bernhardtlab.org/join-us
✨ The Bernhardt Lab at the University of Guelph is recruiting graduate students for 2026! Join us! We have several fully funded grad positions available ✨
Please spread the word!
www.bernhardtlab.org/join-us
#CSEE2025
Had the privilege to attend the Satellite meeting for Future Leaders In Canadian Brain Research held by @braincanada.bsky.social
Got to hear updates from some amazing early career researchers!
All days should be WFH days according to Ruby. Although she wants more pets and less proofing of manuscripts & grading.
New science couple unlock. Today @drssfs.bsky.social & I had papers accepted! Shaun happens to also be a co-author on the paper from my lab. So, double congrats to her.
Also, my paper is my greatest academic albatross. So, I'm pleased to have this out!
The Department of Molecular and Cellular Biology at the University of Guelph is at it again!
Continuing our cluster hires with tenure-track Assistant Professor positions in Immunology and Virology (1 position each)!
careers.uoguelph.ca/job/Guelph-A...
careers.uoguelph.ca/job/Guelph-A...
https://www.eventsforce.net/biochemsoc/frontend/reg/thome.csp?pageID=121401&eventID=227&CSPCHD=001001000000IrVw71GSKcqgqTVkzjZlSk4daZZ3dB6xK_iLWh
Hey all you lipid freaks, join me & other lipid obsessed people talk about protein lipidation! If you've never attended, first drink is on me or @pjenkinslab.bsky.social
Roles and regulation of protein lipidation in health and disease
27-29 August 2025
Exeter College, Oxford
@biochemsoc.bsky.social
Was quite the experience to visit our old postdoc department being on the other side of the lunch table during the career session & having trainees ask us about our career paths. Thanks again to Gareth Thomas for inviting us. @drssfs.bsky.social followed up with an excellent talk of course.
The NeurdyPhagy Lab is in Montreal talking all about palmitoylation in ALS MND. Stop by our posters & say hi.
@jesuisyasmeena.bsky.social
@cailyncreative.bsky.social
Vacation Ruby. It's been a ruff day (we got scooped on a big story), but Ruby always makes it better (for context, we had charcuterie for dinner & two of those pics are of her trying to go under the table).
It looks great!
Yes it absolutely does!