What if you got to work with some of your best friends on a science project? I can't publish how fun this was, but I can show you the data (🧵)! Last week, we posted our second neutrophil swarming paper to bioRxiv and I wanted to post my favorite videos here~
www.biorxiv.org/content/10.6...

Our latest work on shape-programmable tissues is out in @science.org. By positioning topological defects in cellular nematics, we encode frustrated 2D force fields that relax into predictable 3D shapes. Collaboration with Marino Arroyo’s lab, led by @pauguillamat.bsky.social at @ibecbarcelona.eu.

Drosophila border cells are beautiful to watch… but far from easy to image. Kudos to the brave and skilled @vitoryang.bsky.social, who took on the challenge of establishing border cell migration imaging in the lab! His movies are astonishing, and now our first-ever study on #cell #migration is out!

"We want to see the academic publishing industry change in a way that benefits science, not just profits"

q.e.d Science Critical Thinking AI for constructive criticism and science evaluation

🤖AI tools for peer-review?

I want to share my experience using q.e.d. science (www.qedscience.com), a reviewing tool with high-profile endorsements. I will report results and my impressions from the use /1

Open positions - MuSkLE First competitive call open! The first competitive call in the frame of the MuSkLE programme, which aims at selecting 17 doctoral fellows, opens on 6th March 2026 and closes on 6th May 2026. The open ...

📢 PhD position in our lab! (MSCA COFUND)
About dystrophin in Drosophila muscle progenitor cells 🧬🪰
#PhDPosition #DevBio #Drosophila #StemCells
For candidates from outside France or have lived in France <12 months in the last 3 years.
More info 👇 (Project #16)
www.muskle.eu/recruitment/

Impaired stem cell migration and divisions in Duchenne muscular dystrophy revealed by live imaging - Nature Communications Using live-imaging in vivo and ex vivo, Sarde et al. show that dystrophic muscle stem cells have precocious differentiation through symmetric divisions and impaired migration, with differential impact...

Bravo Liza, Brendan and colleagues for the elegant work on multiple live imaging strategies to untangle mechanisms of muscular dystrophy! www.nature.com/articles/s41...

The 59th Annual Meeting of the Japanese Society of Developmental Biologists | Confit 第59回日本発生生物学会大会の電子抄録サイトです。

🚨🚨🚨 1/2
SFBD & JSDB joint meeting, June 9–12 in Hiroshima. Travel grants cover registration + part of travel/housing. Short talks & posters available. Students, postdocs & early-career researchers encouraged to apply by Feb 28.
pub.confit.atlas.jp/en/event/jsd...

Tissue mechanics and systemic signaling safeguard epithelial tissue against spindle misorientation Bosveld et al. identified a multilayered system of safeguards that reuses homeostatic mechanisms to maintain epithelial integrity and cell number in the face of spindle misorientation. This work delin...

How resilient are tissues to cell mispositioning and loss, and how do they restore their cell numbers?

Check our latest work, from @ybellaichelab.bsky.social
Congratulations to all authors.

Artwork from the artist @lale-alpar.bsky.social
(lalealpar.com)

www.cell.com/developmenta...

Our take on a really interesting new study by the Franz lab at UCL, a version of epithelial polarity where you would not expect it! Read our Spotlight and the original paper!

Sign up date coming quickly!
Come join us in beautiful Roscoff for this Conference Jacques Monod on Developmental regulation: from molecular to ecological niches
May 18-22, 2026 Roscoff, France
Abstract deadline: January 31, 2026
Apply here: cjm.sb-roscoff.fr/en

i think they are at VDRC.

#art 🎨 | Quand l’art devient expérimental & que chaque spectateur devient 🧑‍🔬.
A l'occasion du spectacle 'Architectures vivantes’ du @museeorsay.bsky.social qui aura lieu les 24 et 25 janvier prochains, @manuelthery.bsky.social, directeur scientifique du projet revient sur cette expérimentation en 📽️

Genetic sex of enteric neurons enables ovarian relaxin to gate maternal gut plasticity Animals must align intestinal plasticity and feeding with reproductive state, yet the checkpoint that gates these adaptations is unknown. Here we show that an ovary-to-enteric-neuron axis gates the on...

📣First preprint of the lab📣 Did that really happen?😅

Enteric neurons, aka somatic postmitotic cells, must hold on to their sex identity tight, to deliver a tuned response to signals from the ovary that instruct the animal to engage sex-matched behavioural programmes.
www.biorxiv.org/content/10.6...

Happy New Year 2026!

This year, Hadi Boukhatmi, Régis Giet and I are delighted to be organising the 36th French Droso Meeting in Brittany, from 5 to 8 October.
A great line-up of speakers

Mark the date in your diaries !

The meeting website containing all the details will be opening very soon.

Special Issue The Extracellular Environment in Development, Regeneration and Stem Cells Guest Editors: Alex Hughes (University of Pennsylvania) Rashmi Priya (The Francis Crick Institute) Submission deadline: 1 March 2026 Development Call for papers

Call for papers

Submit your latest in vivo and in vitro #DevBio research to our upcoming special issue – The Extracellular Environment in Development, Regeneration and Stem Cells

Guest Editors: Alex Hughes and Rashmi Priya

Deadline: 1 March 2026

journals.biologists.com/dev/pages/ex...

The brand new website of the Bischoff lab

... together with my SciArt Gallery :)

So excited to share this as a new junior PI:

My brand-new lab website! 🎉🪰🌀
www.bischofflab.com

Please pass it on to young, motivated researchers looking for PhD positions 😊

And for the #FluorescenceFriday community: don’t miss the SciArt Gallery!

#CellBio #DevBio #PhDjob #PhDposition #Science

I am very excited to announce the opening of the submission site for the upcoming Conférences Jacques Monod on Developmental Biology, May 18-22, 2026 cjm.sb-roscoff.fr/en/conferenc...
@lionlchristiaen.bsky.social and I have an exciting program of speakers and slots for selected short talks, etc.

Want to join a happy bunch 🥳 to organise meetings, outreach activities and other initiatives about developmental biology in France? Apply and/or vote 🗳️!

On the cover - Congrats @jeromeavellaneda.bsky.social @nunoluis.bsky.social
flies fly! @fly-eds.bsky.social www.cell.com/developmenta...

Is science too obsessed with metrics, large-scale projects & “blockbuster” outputs? Desai & Jun argued that preserving the "auteur" spirit of individual creativity, exploration and risk-taking is essential for maintaining the creativity that drew us into science in the 1st place.

TET exhibits enzymatic-independent and-dependent functions during Drosophila flight muscle development and aging - Skeletal Muscle Background Enzymes of the Ten-Eleven Translocation family are responsible for 5-methylcytosine (5mC) oxidation and play a key role in regulating DNA demethylation during various developmental processe...

Glad to share our latest work showing that #drosophila epigenetic enzyme TET controls muscle development independently of its catalytic activity but prevents muscle aging in a catalytic-dependent manner!
Congratulations to Vincent and Emilie @igred.fr !

links.springernature.com/f/a/L1ogzL3H...

Reaffirming the value of model organisms in training scientific minds - Nature Cell Biology As biomedical research prioritizes human models and translational promise, classic model organisms are increasingly dismissed. Here we argue that they have a lasting value, both in enabling discovery and in cultivating scientific thinking, by training researchers in systems reasoning, integrative thinking and independent inquiry.

PREACH!

www.nature.com/articles/s41...

Remote control of AMPK via extracellular adenosine controls tissue growth - Nature Cell Biology Zhang et al. demonstrate that AMPK can be activated by signalling metabolite, adenosine, under non-stress conditions during Drosophila development. The intestine regulates adenosine levels, thus, remotely controlling wing disc AMPK activation and growth.

💫NEW: @telemanlab.bsky.social & co demonstrate that #AMPK can be activated by signaling metabolite, #adenosine, under non-stress conditions during #Drosophila development. The intestine regulates adenosine levels, thus, remotely controlling wing disc AMPK activation and growth.
bit.ly/4gX6njF

Black and white portrait of John Gurdon, 1971

John Gurdon, former Group Leader and Head of @cellbiol-mrclmb.bsky.social has died.
Despite calling himself a "total non-intellectual” his work to reprogramme somatic cells to pluripotent stem cells transformed the field of developmental biology.
More: www2.mrc-lmb.cam.ac.uk/john-gurdon-...
#LMBNews

Latest from ours: www.cell.com/cell-reports...

This is two stories in one: a case study/cautionary tale on developing genetic tools in new organisms, and the first hint at a gene regulatory network for choanoflagellate multicellular development (which turn out to involve a Hippo/YAP/ECM loop!) A 🧵

40 years since the Heidelberg genetic screen that revolutionized developmental and cell biology ABSTRACT. Our current understanding of the molecular basis of embryonic development and the shared machinery underlying this remarkable process has its roots in three papers published 40 years ago, wh...

You can read Mark's 2024 @dev-journal.bsky.social Review article here: doi.org/10.1242/dev....

Pvf1-Pvr-mediated crosstalk between trachea and gut guides intestinal stem cell migration to promote gut regeneration - Nature Communications Adult stem cells often reside in specialized niches that they exit upon injury. Here they show that in Drosophila, after damage the gut-associated trachea produces the PDGF-VEGF-related ligand Pvf1, which acts as a guidance cue directing ISC migration toward injury sites.

Excited to share our last paper describing how intestinal stem cell migration promotes gut regeneration!
www.nature.com/articles/s41...

🚀 Our new paper is out @natmethods.nature.com!

Kuffer & Marzilli engineered conditionally stable MS2 & PP7 coat proteins (dMCP & dPCP) that degrade unless bound to RNA, enabling ultra–low-background, single-mRNA imaging in live cells.

🔗 www.nature.com/articles/s41...
🧬 www.addgene.org/John_Ngo/

I have gotten a bit behind at sharing the lab’s latest work - this paper is now published - check it out! www.cell.com/cell-reports... Long story short: insulin is the major determinant of female fat storage, with a relatively minor effect on males.