Really interesting #neuroscience #research in #drosophila suggesting that some neurons immediately postsynaptic to sensory neurons can release a transmitter at low activation levels, but a neuropeptide at high activation levels and that this differential release mediates appetitive or aversive […]
Bendless-mediated K63 ubiquitination modulates cellular signalling to regulate Drosophila hematopoiesis
#Drosophila
This led us to ask 2 main Qs. First, as the site of insemination, does the spermalege is behave like a reproductive tract? We found this new organ behaves transcriptionally like a reproductive tissue, expressing immune and reproductive genes like #Drosophila Sex Peptide Receptor tinyurl.com/4kv6e542
I have presented my talk in various formats but I feel I still don't have the apt ending. Its like that standup comic whose set doesnt close well. How do people prep their talk ending ? I feel I am summarizing the story yet the big picture isnt coming across. #academia #phdlife #scicomm #drosophila
Polyploidy reprograms epithelial cells for motility and phagocytosis via stress signaling
#Drosophila
Multi-Omics Analysis Reveals Coordinated Adaptations in Genes, Metabolism, and Gut Microbiota Underpinning Herbivory in Lordiphosa Flies
#Drosophila
COF-PEI-PEG nanocarriers enhance dsRNA delivery to improve RNAi-based insect pest control
#Drosophila
Image of two fly heads. The left one has normal eyes, while in the right one the eye is degenerated. Eye degeneration is caused by eye specific expression of a RNAi construct against eyes absent (eya), an essential gene for eye morphogenesis. The eya RNAi construct is located on the vector backbone of the donor plasmid that was used in this CRISPR knock-in experiment.
Chasing donor backbone insertions in #CRISPR knock-in experiments is a great way to waste an afternoon (or more), unless you use a dominant marker. We like this one from the Carthew lab, in which animals containing the backbone have degenerated eyes:
www.tandfonline.com/doi/full/10....
#Drosophila
Development of an Approach for Parasegment-Specific Labeling of Nuclei in Drosophila melanogaster Embryos
#Drosophila
Want to learn more?
📰 Brown Daily Herald piece: www.browndailyherald.com/article/2026...
📄 Full paper: www.nature.com/articles/s41...
#Neuroscience #Drosophila #FeedingBehavior #Neuromodulation #Connectome #BehavioralNeuroscience
Raw and processed datasets on oxidative stress resistance, peroxide accumulation and fecundity in high-fat diet-fed Drosophila melanogaster subjected to alpha-lipoic acid and climbing interventions
#Drosophila
CryAB-driven amyloidogenesis in Drosophila muscle engages extracellular vesicle pathways for cellular release
#Drosophila
Arp2/3 involvement in intercellular bridge membrane fluctuations and constriction during neural stem cell divisions
#Drosophila
Preconception exposures of female mice to a panel of metabolic disruptors induce sexually dimorphic metabolic perturbations in their offspring
#Drosophila
Glia generate distinct visual processing centres by locally inhibiting ERK activity in an optic lobe neuroepithelium
#Drosophila
The Anticarcinogenicity Effects of Piperine and 4,5-Dihydroxypiperine in Drosophila melanogaster Somatic Cells
#Drosophila
CCAP receptor 2, rather than CCAPR1, functions in pupal ecdysis in the 28-spotted larger potato ladybird
#Drosophila
MicroRNA-Mediated Obstruction of Stem-loop Alternative Splicing (MIMOSAS) regulates long-range alternative splicing in Drosophila
#Drosophila
Mechanisms Underlying the Initiation and Termination of Collective Cell Migration: Perspectives for Understanding Development and Cancer Metastasis
#Drosophila
Distinct cellular effects of myotonic dystrophy type 2 RAN tetrapeptides in Drosophila melanogaster
#Drosophila
Nckx30c, a Drosophila K(+)-dependent Na(+)/Ca(2+) exchanger, regulates temperature-sensitive convulsions and age-related neurodegeneration
#Drosophila
Clock-gated morning rush hour of glucose utilization depicted as highway traffic. In the morning (left), clock-controlled food intake at dawn results in high glucose concentration in Drosophila body tissues, analogous to higher number of vehicles on the highway. This increased “traffic flow”, defined by the total number of vehicles passing a given point in a given time, is aided by the opening of the “7AM-11AM only” lanes that are gated by the circadian clock. This is analogous to higher metabolic flux in the morning hours in fly tissues. In other times of the daily cycle (right), both glucose concentration (number of cars) and pathway flux (traffic flow) are low. Vehicle icons were generated by authors using Google’s Nano Banana 2 from the prompts such as “create a top-view of a car icon in white background”, February 16, 2026.
The #circadian clock & cellular #metabolism: @drummonk.bsky.social & @joanna-chiu.bsky.social explore a @plosbiology.org study showing how #glucose #metabolism changes during the day in #Drosophila and how it is disrupted in clock & sleep mutants 🧪 Paper: plos.io/3Olm1M1 Primer: plos.io/4sUov2g
Clock-gated morning rush hour of glucose utilization depicted as highway traffic. In the morning (left), clock-controlled food intake at dawn results in high glucose concentration in Drosophila body tissues, analogous to higher number of vehicles on the highway. This increased “traffic flow”, defined by the total number of vehicles passing a given point in a given time, is aided by the opening of the “7AM-11AM only” lanes that are gated by the circadian clock. This is analogous to higher metabolic flux in the morning hours in fly tissues. In other times of the daily cycle (right), both glucose concentration (number of cars) and pathway flux (traffic flow) are low. Vehicle icons were generated by authors using Google’s Nano Banana 2 from the prompts such as “create a top-view of a car icon in white background”, February 16, 2026.
The #circadian clock & cellular #metabolism are tightly coupled. Yao Cai & @joanna-chiu.bsky.social explore a @plosbiology.org study showing how #glucose metabolism changes during the day in #Drosophila and how it is disrupted in clock & sleep mutants 🧪 Paper: plos.io/3Olm1M1 Primer: plos.io/4sUov2g
Clock-gated morning rush hour of glucose utilization depicted as highway traffic. In the morning (left), clock-controlled food intake at dawn results in high glucose concentration in Drosophila body tissues, analogous to higher number of vehicles on the highway. This increased “traffic flow”, defined by the total number of vehicles passing a given point in a given time, is aided by the opening of the “7AM-11AM only” lanes that are gated by the circadian clock. This is analogous to higher metabolic flux in the morning hours in fly tissues. In other times of the daily cycle (right), both glucose concentration (number of cars) and pathway flux (traffic flow) are low. Vehicle icons were generated by authors using Google’s Nano Banana 2 from the prompts such as “create a top-view of a car icon in white background”, February 16, 2026.
The #circadian clock & cellular #metabolism are tightly coupled. Yao Cai & @joanna-chiu.bsky.social explore a @plosbiology.org study showing how #glucose metabolism changes during the day in #Drosophila and how it is disrupted in clock & sleep mutants 🧪 Paper: plos.io/3Olm1M1 Primer: plos.io/4sUov2g
Tsang et al. used four species of Drosophila to investigate how climate affects gene expression in different sexes of insects, showing that protein-coding genes and microRNAs have undergone different selection between sexes.
🔗 doi.org/10.1093/gbe/...
#genome #evolution #drosophila
