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Posts by Shefali

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an elderly woman is laying on a couch with a bowl of popcorn . ALT: an elderly woman is laying on a couch with a bowl of popcorn .

Sunita Williams completing the #BostonMarathon, meanwhile me being a busy couch potato πŸ₯”πŸ€·πŸ½β€β™€οΈ

12 hours ago 0 0 0 0

A herculean effort by many, but esp. the first three authors: Ujjwal Rathore, Eli Dugan, and Hunter Thornton working in the Krogan and Marson labs, with a veritable army of collaborators from HARC (harc.ucsf.edu) and beyond.

Press release: gladstone.org/news/scienti... (inc. paper link)

14 hours ago 40 15 0 1

As I am nearing finishing grad school (hopefully 🀞🏽) I am more and more realizing how grad school is not a sprint and rather is a marathon. Somehow I was hoping it'd be a sprint near the end - but that's definitely not the case 😳
#phdlife

16 hours ago 3 0 0 0
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Excited to share a new review by @kocherlab.bsky.social and me:

Nature-inspired neuroscience

We discuss diverse sensory systems and behaviors across the animal kingdom and argue for their integration into neuroscience. New tools in diverse systems are making this possible ✨

tinyurl.com/y5y9du27

1 day ago 191 70 1 8

This πŸ‘‡πŸ½πŸ‘‡πŸ½πŸ‘‡πŸ½πŸ‘‡πŸ½

1 day ago 1 0 0 0
Science | AAAS

Peaceful queen succession in the naked mole rat
www.science.org/doi/10.1126/...

Fantastic new study from Janelle Ayres' lab @salkinstitute.bsky.social @hhmi-science.bsky.social

I am reminded of the wonderful 'queen replacement' experiments carried out by Raghavendra Gadagkar at IISc

2 days ago 21 3 1 0
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πŸͺ± Serving head-to-tail fluorescence πŸ’… Whole-animal FISH in the planaria Schmidtea mediterranea: πŸ”΅ Head 🟣 Gut 🟑 Tail ✨ Masters of regeneration and color coordination πŸ“Έ Image from Viraj Doddihal #FluorescenceFriday
To be featured submit your images here ➑️ forms.gle/PWyaViekkNNn...

3 days ago 29 11 0 0

OMG this is so cool and so much work !
Everyone go and check out this amazing paper !

#Drosophila #worns #mice #lipiddroplets
πŸŽŠπŸ‘πŸ½πŸ˜

2 days ago 2 0 1 0
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News News

Great news from the lab - we’ve been awarded a MIRA (R35)!

This grant provides 5-year support for our research program. We are very grateful to NIGMS/ #NIH for supporting our research. We will be hiring a research technician and a postdoc.

fernandez.lab.indiana.edu/news/index.h...

2 days ago 68 11 8 0
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β€œThe overall message is that internal conflict is a central, not peripheral, feature of organismal biology, and should be considered in studies of development, evolution, cancer and beyond.”

2 days ago 8 1 0 0
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Perks of being in a university which has an amazing music school !!

It's a #musical show tonight - Oklahoma 🀩😍
Rodgers and Hammerstein 🎊

#oklahoma #weekend #friday #phdlife

3 days ago 3 0 0 0
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Twenty years ago, thanks to the CNRS’ ATIP programme (www.insb.cnrs.fr/fr/atip-avenir), I had the opportunity to embark on this wonderful human and scientific adventure. Thank you to all my colleagues and to the funding agencies for making this possible.

3 days ago 14 3 1 0
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My first mentee presented her first poster today - yayy ! Minseo Kim is a phenomenal masters student in our lab & has been working with me for her thesis. She'll soon be applying for MD-PhD programs & will definitely be someone to watch ! #phdlife

@iubiology.bsky.social @tennessenlab.bsky.social

4 days ago 6 1 0 0

I would totally get on a plane for some besan laddoos - I am not even lying πŸ˜…

4 days ago 1 0 0 0

Ufff I love besan laddoo - I might have stop by the Indian store to pick somevthis evening because I won't be able to stop thinking about it πŸ₯Ή πŸ˜‹

4 days ago 1 0 1 0

Congratulations yayyyy πŸ‘πŸ½πŸŽ‰πŸ₯ΉπŸŽŠπŸ₯‚

5 days ago 1 0 1 0
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I'm excited to tell you about the most recent preprint in my lab, demonstrating that a conserved spindle matrix protein, NPP-21/TPR, is required for the stronger checkpoint in germline cells during embryogenesis in C. elegans

5 days ago 61 21 7 0
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joy from inside out is dancing with her arms in the air and saying yay ! ALT: joy from inside out is dancing with her arms in the air and saying yay !

Can I just say - my masters trainee is giving her first poster presentation tomorrow. I am so excited as her mentor. She has been working with me for a while and I am so proud of all the stuff she has accomplished πŸ₯ΉπŸ₯³

Yayyyy πŸ₯‚

#proudmentor

5 days ago 3 0 0 0
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An illustrated summary of the BSDB Spring Meeting 2026 - the Node I recently attended the BSDB Spring Meeting, and decided to spend most of my time at the conference sketching. The result is this illustrated summary -

An illustrated summary of the BSDB Spring Meeting 2026

In this post, @alexneaverson.bsky.social shares her insights on using illustration to share the joy of developmental biology at the 2026 @bsdb.bsky.social meeting.

thenode.biologists.com/an-illustrat...

#SciArt

5 days ago 16 11 0 0
MBE | Transgenerational effects of heat shock on gene regulation and fitness-related traits in natural Drosophila populations

MBE | Transgenerational effects of heat shock on gene regulation and fitness-related traits in natural Drosophila populations

@ewanharney.bsky.social & @gonzalezlabbcn.bsky.social show evidence of transgenerational developmental plasticity as a result of heat shock in fruit flies, documenting gene expression and phenotype changes 3+ generations following heat shock.

πŸ”— doi.org/10.1093/molbev/msag069

#evobio #molbio

5 days ago 10 7 1 0
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I'll soon be visiting @johninnescentre.bsky.social, hosted by C Dean & @jonathandgjones.bsky.social; @cecad.bsky.social & @unicologne.bsky.social,hosted by @bjornschumacher.bsky.social & @frezzalab.bsky.social; & @molgen.mpg.de,hosted by @aktast.bsky.social.

If you're around, come say hi! #EuroTour

6 days ago 7 4 0 0

Senior professors - if you want to help your junior colleagues in these times, I am begging you, review our papers. I have done 25 manuscript reviews in the last 6 years. But my own manuscript is stalled out waiting for reviewers. Relatedly, I won't be doing any more reviews until tenure. πŸ§ͺ

6 days ago 172 47 11 7

Two weeks until the Registration closes for the 1st German Fish Meeting! 🐟πŸ§ͺ Reminder I will be chairing a session for Postdocs in the Job Market. If that's you, apply and tell everyone why fishes are the best and why they should be shoveling $ at you

www.germanfishmeeting.org/from-postoc-...

1 week ago 14 6 0 1

Thomas MΓΌller-Reichert showed that in C. elegans embryos, spindle length scales with cell size, but chromosome segregation dynamics remain constant. In RPE1 cells, 11-12 microtubules are attached end-on to each kinetochore, and monopolar spindles have a twist. #SpindleCroatia2026

1 week ago 10 5 0 0
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De novo formation of cis-regulatory contacts in the absence of NIPBL-driven chromatin loop extrusion - Nature Genetics The authors deplete the cohesin activator NIPBL during the mitosis-to-G1-phase transition. They observe that structural loop formation is impaired proportionally to loop length, while gene activation ...

Excited to read this! @andersshansen.bsky.social @nicholas-aboreden.bsky.social

www.nature.com/articles/s41...

1 week ago 11 5 0 0
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I am totally on board with that, and I find it so liberating 😊

1 week ago 0 0 0 0

A very fun read, with some timely reminders. I suppose it’s to the advantage of research that there really aren’t many (any?) career paths left that offer much in the way of stability and reasonable gratification. Levels the playing field a bit that it’s our *generations* being thrown to the wolves.

1 week ago 8 3 0 0

It's a beautiful read πŸ₯Ή
Some amazing science, advice, and philosophy in here !

"I think coming from outside of biology has given me a kind of curiosity that is perhaps its own superpower" πŸ‘ŒπŸ½πŸ‘ŒπŸ½πŸ‘ŒπŸ½πŸ‘ŒπŸ½

#academia #scicomm

1 week ago 3 0 1 0

Every time me and maa (mom) have a fight this is what I sing for her - Asha ji will always be remembered as an absolute legend 😟

youtu.be/1LPtNHJckpw?...

1 week ago 1 1 0 0
Lineage tracing of NPCs in developing kidney reveals Rac1 required for NPCs formation. (A) Frozen section of Six2Cre;R26RtdT and Rac1fl/fl;Six2Cre;R26RtdT at E16.5 counterstained with DAPI. TdTomato expression labels all Six2+NPC derivatives. Blank arrowheads point to NPCs in cap mesenchyme. Green arrowheads point to SSB. Yellow arrowheads point to glomeruli. Scale bar, 100um.

Lineage tracing of NPCs in developing kidney reveals Rac1 required for NPCs formation. (A) Frozen section of Six2Cre;R26RtdT and Rac1fl/fl;Six2Cre;R26RtdT at E16.5 counterstained with DAPI. TdTomato expression labels all Six2+NPC derivatives. Blank arrowheads point to NPCs in cap mesenchyme. Green arrowheads point to SSB. Yellow arrowheads point to glomeruli. Scale bar, 100um.

#DBfeature

Rac1 is essential for kidney development, by controlling proliferation and self-renewal in nephron progenitor cells.

By Chunmin Dong, Hongbing Liu, Jessica Chang, Eric Yang, Eddie Xu, Samir El-Dahr, Fenglei He

tinyurl.com/4vbjmzak

1 week ago 8 4 0 0