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Posts by Runze Shen

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EEPD1 evolved a unique DNA clamping dimer protecting reversed replication forks Abstract. Exonuclease/endonuclease/phosphatase (EEP)-fold hydrolases are canonically monomeric phosphodiesterases exemplified by APE1, DNase I, and TDP2 nu

My first first-author paper is online! We report the first structure study of EEPD1, a unique EEP-domain-containing member that lost a catalytic Asn. It’s also the first member that dimerises via this very domain, necessary for binding reversed replication fork. academic.oup.com/nar/article/...

1 month ago 1 0 0 0

But it was the weather?

1 year ago 0 0 0 0

I wish they have a save button

1 year ago 2 0 0 0

Thanks! I didn’t think aqueorin should be there. just wondered if a little fragment from digestion accidentally worked as agonist/antagonist

1 year ago 0 0 1 0

Great read indeed for my otherwise dull 4-hr road trip!
Now question 🙋🏻‍♂️
How small for a peptide to be absorbed into blood and again for passing through BBB?
Could one alternative (that is, if it has effect) be a peptide is interacting with protein/receptor?

1 year ago 0 0 1 0
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Last update of our databases for the year.

Download them here:

493 early-career funding opportunities: research.jhu.edu/rdt/funding-...

313 postdoc fellowships: research.jhu.edu/rdt/funding-...

189 PhD fellowships: research.jhu.edu/rdt/funding-...

1 year ago 90 48 3 0
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2024 S2C2 Single-Particle Cryo-EM Image Processing Workshop - YouTube This playlist contains six recordings covering single particle cryo-EM data processing in CryoSPARC from the 2024 Single-Particle Cryo-EM Image Processing Wo...

1/ A new series of #CryoSPARC tutorial videos from this year’s S2C2 #cryoEM image processing workshop are now online! These videos will be interesting to all users and especially those newer to #cryoEM.

www.youtube.com/playlist?lis...

1 year ago 63 30 3 2

Those rock stars following me back will never happen on other platforms.

Hence imposter syndrome?

1 year ago 0 0 0 0
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fyi - you can make very nice figures using PyMol with these custom settings (or modify them to make your own)

1 year ago 36 5 2 0
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So what’s your favourite liquor

1 year ago 1 0 0 0

Good to know! Bet many haven’t fully ditch x for similar reason

1 year ago 0 0 0 0