We are all 🤩 with our work and image being selected for the cover of @natmater.nature.com
Thank you again @brunommcastro.bsky.social !
ALT : This is a PAA bead stuck in a #zebrafisg ISV vessel

Thx Tom 🙏

Thanks Man 🙏

Thx Guy 🙏

This cover is a beautiful ending of one of life's adventures from which you and your colleagues grow so much, at all levels !

Conclusion : time and failures are perfect food for success

We then faced the 🎢 of scientific publishing but were again galvanized by failures. We fought and benefited from the understanding of editors and reviewers in a constructive and productive discussion.

The project was then beautifully taken over by Valentin Gensbittel and @naelosmani.bsky.social in the lab, based on the previous work of many in the lab and the help of many many many people.

Intense brainstorming with the brilliant mind of Jochen Guck (I miss him so much). Luckily, Ligue contre le cancer and many others took over and allowed use to pursue some preliminary data obtained in the lab.

Some context 💡 : It all started with a simple concept & question and during a sabbatical at @garvaninstitute.bsky.social (awesome opportunity for scientists to actually do science) where I drafted a later-failed European Research Council (ERC) proposal.

💥 We made the COVER 🤩 of @natmater.nature.com !

CELL VISCOSITY 🎈 IN METASTATIC EXTRAVASATION

Check the entire issue here : lnkd.in/e9USS44n

@inserm.fr @unistra.fr

#zebrafish
#mouse
#metastasis
#mechanobiology
#imaging
#materials

Note : Image's credit is V.Gensbittel (PAA bead in a ZF ISV)

Very nice 👍

Really sorry to hear about your daughter, breaking my heart.

I would 🤗, but quoting K.Konstantopoulos 😜

Check out the french 🇫🇷 digest we just published in MédecineSciences

Awesome work (this one and the original) by @katkajerabkova.bsky.social & @hyennev.bsky.social in the lab

Digest : www.medecinesciences.org/fr/articles/...

Not just soft 🎈

Many thanks to the team of K.Konstantopoulous #JohnsHopkins for throughly discussing our recently-published story in @aacrjournals.bsky.social #CancerResearch

Highly appreciated 🙏

Link : aacrjournals.org/cancerres/ar...

Our original paper :

www.nature.com/articles/s41...

Check out the awesome highlight (+ video) of our recent work on the #biophysics of #metastasis published by Le Point, by O.HERTEL

🔗 lnkd.in/eywzr8kn

🖥️ dai.ly/xa0dwds

Such a blast to see our #zebrafish 🐠 experiments making the (web) front page (but there are also 🐁 ones in the original paper 😜)

Awesome 👏 work !

💡 Interested in mechano-immunology (or biology of adult B-ALL) ?

💥 We have an #MSCA postdoctoral fellowship offer for you
@ec.europa.eu

🖥️ : euraxess.ec.europa.eu/jobs/hosting...

🏙️ Where ? In beautiful #Strasbourg #CRBS @inserm.fr @unistra.fr

🥼 Interested ?
📧 jacky.goetz@inserm.fr

💡 Interested in mechano-immunology (or biology of adult B-ALL) ?

💥 We have an #MSCA postdoctoral fellowship offer for you
@ec.europa.eu

🖥️ : euraxess.ec.europa.eu/jobs/hosting...

🏙️ Where ? In beautiful #Strasbourg #CRBS @inserm.fr @unistra.fr

🥼 Interested ?
📧 jacky.goetz@inserm.fr

France should also not forget to preserve their best minds !

Tumor cell in the maze of the lung vasculature in a mouse.

A #research team investigated how the mechanical properties of tumor cells influence their metastatic pathway.
🔑 🔍: Viscosity – rather than elasticity – determines how tumor cells invade surrounding tissue.

👉 mpzpm.mpg.de/news/news-de...
📸 V. Gensbittel, J. Goetz

#science #biophysics #metastasis

Thank you 🙏
@inserm.fr @unistra.fr

Thank you 🙏
healthmedicinet.com/mechanical-v...

@inserm.fr @unistra.fr

New study finds cancer spread driven by how “thick” tumour cells are

🧬 New study in Nature finds cancer spread depends on how “thick” tumour cells are. Higher cell viscosity helps them survive blood flow and escape into new tissues - a key step in metastasis. 🔬 www.nature.com/artic... #CancerResearch #Science #Health

Cell viscosity influences haematogenous dissemination and metastatic extravasation of tumour cells - Nature Materials The viscosity of tumour cells is shown to govern their ability to disseminate through the bloodstream and extravasate, establishing a key biomechanical factor of metastasis.

Cell viscosity influences haematogenous dissemination and metastatic extravasation of tumour cells

go.nature.com/4jZ8OUu

🙏

Cell viscosity influences haematogenous dissemination and metastatic extravasation of tumour cells - Nature Materials The viscosity of tumour cells is shown to govern their ability to disseminate through the bloodstream and extravasate, establishing a key biomechanical factor of metastasis.

www.nature.com/articles/s41...

💡 Have you ever wondered how #circulating #tumor cells squeeze through narrow #capillaries during hashtag#metastasis ?

💥 We did, check out our latest publication just out #NatureMaterials: rdcu.be/eZHxJ

Un plaisir aussi de voir Elodie Marchal et Laurie Nemoz-Billet jouer avec notre cytométre de déformabilité développé par Jochen Guck et son équipe Martin Kräter #Rivercyte, et Laetitia PAULEN à la paillasse