What if you got to work with some of your best friends on a science project? I can't publish how fun this was, but I can show you the data (🧵)! Last week, we posted our second neutrophil swarming paper to bioRxiv and I wanted to post my favorite videos here~
www.biorxiv.org/content/10.6...
Our latest work on shape-programmable tissues is out in @science.org. By positioning topological defects in cellular nematics, we encode frustrated 2D force fields that relax into predictable 3D shapes. Collaboration with Marino Arroyo’s lab, led by @pauguillamat.bsky.social at @ibecbarcelona.eu.
Really excited to share our new paper in @nature.com! We uncovered how a physical instability of the cytoplasm coupled with the cell cycle drives cytoplasmic partitioning in early embryos #zebrafish #drosophila. Read more in this🧵 www.nature.com/articles/s41... 🤩
@poldresden.bsky.social @mpi-cbg.de
![The Two Cytoskeletal Problem // Asynchronous Defense [28]](https://cdn.bsky.app/img/feed_thumbnail/plain/did:plc:cqbyzh5yytji443ckaga4biv/bafkreifywiasxypgigzyx4uaaqk2axya6sjwdeyae53qtjjqy5sjgfqxtm)
We are trying out author rebuttals, so listen to the second half to hear what the authors have to say!
Video links, because the videos are amazing:
www.patreon.com/posts/two-cy...
www.youtube.com/watch?v=zZ0C...
Whole organism 3D mapping reveals universal branching topology and biophysical optimization governs vascular and nervous system development
Read about our work here: www.biorxiv.org/content/10.6...
Examples of the new model organism shirts for sale on the SDB merchandise website
Excited to share that @socdevbio.bsky.social has a new and improved merch store! Rep your fav model organism in one of the Society’s new original designs 🤗 sdb-official-merch.printify.me
Every week we put up a short video of some of the papers we could find in the field of biophysics (very broadly defined) that were published that week. www.youtube.com/watch?v=cu5i...
Then we put all the papers we could find here: bezialemma.com/LemmaJournal...
I suppose it's better late than never to mention that this September I started an Assistant Professor position at Rowan University @rowancsm.bsky.social. We will be doing cool work with chameleons 🦎 to understand early development, especially left-right patterning view.rowan.edu/the-human-pu...
✨Join us in 1h!
#EvoDevoMondays
Register here: docs.google.com/forms/d/e/1F...
Make your own PDMS+micromirror device for single-objective light-sheet SMLM: www.biorxiv.org/content/10.6...
This week's ep. is about the demonic behavior of molecular motors.
rss.com/podcasts/the...
or
www.youtube.com/watch?v=0FiL...
@lsprahl.bsky.social and Ronald Canlla in the lab just published a detailed study on remote-controlled epithelial budding morphogenesis. We can direct budding, tubule elongation, and perhaps branching in human kidney organoids via a light-activated RET receptor.
www.biorxiv.org/content/10.6...
The longstanding mystery for how mitochondria segregate and position their DNA has been solved!
Read all about it:
www.science.org/doi/10.1126/...
@jclandoni.bsky.social
Here is Juan and I at the 4th of July parade at MBL physiology
Our preprint list highlighting new tools and techniques in imaging is now up on FocalPlane. Check it out, and let us know if we are missing any research that we should add to the list.
focalplane.biologists.com/2026/04/03/m...
I'm so pleased to see this work on neural crest development out in Nature today! This was a truly fantastic collaboration with @gleesonlab.bsky.social, Keng loi (Harry) Vong and @xiaoxuyang.bsky.social. Huge thanks to everyone involved 👏 🧪🐣 #devbio
www.nature.com/articles/s41...
We are very excited for the next Zoom seminar of Metabolism in Development & Physiology!
When:
Thursday, 9th of April, 16:00 CET
Speakers:
· Xingbo Yang, Technische Universität Dresden
· Yi Xuan Low, MRC Laboratory of Medical Sciences
Join the zoom meeting: ucl.zoom.us/j/9390124290...
🌸Spring Cleaning Series - How to clean oil immersion objectives
✨Today, we’re focusing on cleaning your oil or silicone oil immersion objectives. Clear data starts with a clean lens.
🔗 Download full document: https://bit.ly/4sOfjgF
![The Path Between the Cells // Leica's Name in Lights [25]](https://cdn.bsky.app/img/feed_thumbnail/plain/did:plc:cqbyzh5yytji443ckaga4biv/bafkreianr67hbm4dy737pshlbbilof4byhqi6eawffs2tgmbjmy7vef6qy)
WHAT ARE TUNNELING NANOTUBES!? My favorite episode of this project so far: #25 The Path Between the Cells
www.youtube.com/watch?v=VKLJ...
Our paper on inferring Wnt signals just got published with PRR! doi.org/10.1103/f7qj...
We use ideas from efficient coding to infer the best possible set of Wnt signals for cells to respond to: these signals are discrete, and do not need to be fine-tuned. (1/n)
Follow-up from last week’s #FluorescenceFriday 🐟✨
Took a closer look at the gill comb “tooth” — the actin microridges of the enveloping epithelial layer almost look like microscopic fingerprints, each with a distinct pattern
#Zebrafish #DevBio #Microscopy #SciArt
Kinase KEY1 controls pyrenoid condensate size throughout the cell cycle by disrupting phase separation interactions
Phosphorylation control of Rubisco condensation in pyrenoids!
www.nature.com/articles/s41...
Congratulations! Crazy that we live in an environment where getting to keep doing a job and keep your family together is such a rare accomplishment.
The words "in vivo" are completely unnecessary.
Today in Nature Cell Biology, a collaborative effort across labs (Jonikas, Wingreen, Brangwynne) at Princeton discovers the key to regulating a biomolecular condensate. Congrats to first authors Shan He and Linnea Lemma! molbio.princeton.edu/news/2026/ke...
The paper from @linnealemma.bsky.social 's postdoc is officially published. Here is a publicity piece from Princeton which is a decent quick summary: molbio.princeton.edu/news/2026/ke...
This developing quail embryo looks like it's thinking fiery thoughts for #FluorescenceFriday 🐣🔥🧪. Imaged by the fantastic @vanderspuy.bsky.social
The next Zoom seminar on metabolism in development will be on 12 February, 4pm CET / 3pm GMT / 10am EST. Our speakers for February will be:
Bezia Lemma (Princeton, USA)
Jonathan Rodenfels (MPI CBG, Germany)
Sign up for the mailing list to get the Zoom link: docs.google.com/forms/d/e/1F...
To the right of that squiggly line, is cured glue above (not in) the chamber, and the squiggly line is the border of that glue. The glue seals the ends of the chamber to keep liquid from evaporating over time.
Back in 2016, I spent some time centrifuging chambers containing a kinesin/microtubule -based active gel so that all the material ended up on one side of the chamber. Then recorded how long it took to expand.
