Bridging the membrane lipid divide: bacteria of the FCB group superphylum have the potential to synthesize archaeal ether lipids pmc.ncbi.nlm.nih.gov/articles/PMC...

Romain Koszul

🥈 CNRS Silver Medal 2026 → Romain Koszul

For his interdisciplinary contributions to chromosome biology and pioneering genomic methodologies (HiC-scaffolding, metaHiC), decoding how genomes organize in 3D across all domains of life.
@rkoszul.bsky.social @cnrs.fr

Dear Nanopore folks, could you give an advice about an issue that my lab has with direct RNA sequencing on MinION. We're doing RNA004 sequencing of various samples and again and again, there's a staggering amount of reads with just repetitive AAG triplet. This happens for weird IVT RNA and […]

We are recruiting postdocs to work on antimicrobial resistance and bacterial cell envelope biology. PLEASE SHARE.

Local peptidoglycan composition defines division site selection in Streptococcus pneumoniae Nature Microbiology, Published online: 07 April 2026; doi:10.1038/s41564-026-02322-6Sequential peptidoglycan carboxylase activity of DacA and DacB generates a local peptidoglycan signature that recruits MapZ and establishes the division site at the Streptococcus pneumoniae cell equator.

Out Now! Local peptidoglycan composition defines division site selection in Streptococcus pneumoniae #MicroSky

Division bactérienne : Un signal transitoire positionne le site de division chez les streptocoques Streptococcus pneumoniae présente des spécificités dans son mode de division.

#ResultatScientifique🔎| Décryptage de la division chez Streptococcus pneumoniae 🦠

✍️ Christophe Grangeasse
👋 @cnrs-rhoneauvergne.bsky.social @mmsb-lyon.bsky.social
📕 @natmicrobiol.nature.com
👉️ buff.ly/4BWTJf7

L'actu CNRS Biologie ⤵️

Amazing work, congratulations 🦩☀️

So happy to see this finally published in @plosbiology.org!

This is the first chapter of @julielebris.bsky.social PhD thesis demonstrating how capsules are exchanged by plug-and-play dynamics
w/ @epcrocha.bsky.social
#microsky @klebclub.bsky.social
Link below-
Check out her 🧵 for more details!

Who let the wolves in? Genetic record for domestic dogs pushed back by 5,000 years The oldest ancient dog genomes on record all come from a population that lived alongside Ice Age hunter-gatherers across Europe and the Middle East.

Dogs were hunter-gatherer's best friend

go.nature.com/4bS8CCZ

Marthe Gautier, découvreuse oubliée du chromosome de la trisomie 21

Marthe Gautier est à l’origine de la découverte du chromosome surnuméraire de la trisomie 21, anomalie génétique qui touche 50 000 personnes en France. À l’occasion de la Journée mondiale de la trisomie 21, retour sur le parcours de cette scientifique invisibilisée, avec la biologiste Julie Batut.

Super nice

Living patescibacterial (CPR) cells are a rare sight! Meet Strigamonas methylophilicida, a parasite of methylotrophic proteobacteria we just described in our latest paper:

doi.org/10.1128/mbio...

2 year fellowship available in AMR research www.medicalresearchfoundation.org.uk/grants/antim...

(bacterial) cell divisionists take note 👇

the schwille lab did it again! now adding FtsN*) to the party, with FtsA, FtsZ and the Min gang already on board...

*) cytoplasm.domain
thx séamus for pointing this out🙏 #MicroSky

Postdoctoral researcher in molecular and cellular bacteriology - ERC CoG VAMPIRE The research group of Prof Géraldine Laloux at the de Duve Institute (UCLouvain) is looking for a highly motivated postdoc to elucidate the molecular factors underlying bacterial prey-predator interac...

#MicroSky Please RT
@erc.europa.eu-funded postdoc position in my lab to identify the molecular basis of prey-predator interactions using our favorite micro-vampire Bdellovibrio exovorus as a model.
Let's find what the bite is made of! 🧛
Flexible start date.
Info: euraxess.ec.europa.eu/jobs/415877

Join @berasymbionts.bsky.social , @tatsuyanobori.bsky.social and us for a postdoc on the remarkable developmental biology of symbiosis!

Applications are due March 25th 🪲🦠

@johninnescentre.bsky.social @thesainsburylab.bsky.social

rambaut/figtree Automatically exported from code.google.com/p/figtree - rambaut/figtree

The first version of FigTree was released nearly 20 years ago and it is still widely used (including by me). But there are currently 85 issues on the GitHub repo (github.com/rambaut/figt...) and some of them I don’t really like the look of.

It’s finally out! Together with @embopress.org and
@reviewcommons.org, we conducted a structured side-by-side comparison of human peer review and our AI scientific review (see thread 👇👇👇🔥).

Congrats Pedro
Beautiful work !

New preprint out on bioRxiv!

www.biorxiv.org/content/10.6...

Can conjugative plasmids be used to control plasmid and pathogen spread?

Follow me down the rabbit hole that led to this story 🧵

There's still time to apply for this PhD position!

Oxygen metabolism in descendants of the archaeal-eukaryotic ancestor - Nature Sequencing of marine sediments finds 136 newly identified Heimdallarchaeia and several novel lineages, and indicates that Heimdallarchaeia evolved distinct metabolic capabilities from other Asgardarchaeota, in conditions that may have given rise to early eukaryotes.

Nature research paper: Oxygen metabolism in descendants of the archaeal-eukaryotic ancestor

go.nature.com/4rSfRRw

Oxygen metabolism in descendants of the archaeal-eukaryotic ancestor - Nature Sequencing of marine sediments finds 136 newly identified Heimdallarchaeia and several novel lineages, and indicates that Heimdallarchaeia evolved distinct metabolic capabilities from other Asgar...

#NatMicroPicks

Aerobic archaeal-eukaryotic ancestor? 🦠🫁

The ancestor of eukaryotes may have combined hydrogen metabolism with aerobic respiration, shaping early cellular complexity.

#MicroSky

www.nature.com/articles/s41...

Oxygen metabolism in descendants of the archaeal-eukaryotic ancestor - Nature Sequencing of marine sediments finds 136 newly identified Heimdallarchaeia and several novel lineages, and indicates that Heimdallarchaeia evolved distinct metabolic capabilities from other Asgar...

At long last! Check out the link to our publication in @nature.com to learn more. doi.org/10.1038/s415...
12/12

Eukaryogenesis in light of an expanded catalogue of Asgard genomes. a, Simplified, scaled timeline spanning from before the Last Asgard archaea Common Ancestor (LAsCA) to today. Thin bands mark predicted time ranges of relevant events (for example, GOE), thicker bands represent processes (for example, eukaryogenesis), and brackets indicate the period shown in b. The timeline further highlights milestones, including potential early eukaryotic fossils60 and the modern-day co-occurrence of Heimdallarchaeia and Alphaproteobacteria observed in this study (interaction likely originated earlier).

Fig. 1 | Expanded genomic diversity of Asgard archaea. a, Maximum-likelihood phylogeny based on 47 non-ribosomal markers (NM47)using the WAG + C10 + R4 model with 100 nonparametric bootstrap pseudoreplicates, including 869 Asgardarchaeota MAGs and 309 outgroup genomes. The blue branches (lower right) indicate the new Asgardarchaeota classes, Ranarchaeia, and the recently proposed Asgardarchaeia4. The concentric rings denote (in to out): the predicted genome size, metabolic guilds based on Pfam clustering, sampling locations, and black stars on the outside mark MAGs added by this study. Asgard, Asgardarchaeia; Atabey, Atabeyarchaeia; Baldr, Baldrarchaeia; Frey/Jord, Frey/Jordarchaeia; Gerd, Gerdarchaeales; Heimdall, Heimdallarchaeaceae; Hel, Helarchaeales; Hermod, Hermodarchaeia; Hod, Hodarchaeales; Kari, Kariarchaeaceae; Loki, Lokiarchaeales; Njord, Njordarchaeales; Odin, Odinarchaeia; Ran, Ranarchaeia; Sif, Sifarchaeia; Thor, Thorarchaeia; Wukong, Wukongarchaeia. b, SR4-recoded phylogeny of the same genome set inferred with the model GTR + C60 + G and 100 nonparametric bootstrap pseudoreplicates (Methods). This updated catalogue constitutes a large increase in the medium- to high-quality publicly available genomes (completeness >50% and contamination and redundancy <10%) with 65.3% from the Guaymas Basin and 34.7% from the Bohai Sea. The encircled numbers represent MAGS added by this study. The scale bars in bothsubpanels represent the average number of substitutions per site.Map created in BioRender; Appler, K. https://biorender.com/147ieoc(2025).

Our work is published today: ‘Oxygen metabolism in descendants of the archaeal-eukaryotic ancestor’. This was a huge effort lead by @katyappler.bsky.social. Extremely grateful to have been a part of this amazing project! 😊🦠🧬

Links: www.nature.com/articles/s41...
www.nature.com/articles/s41...

You go, Katy! 🚀
I’m so proud of you, and so happy to finally see this in its final form!

Count me in on your corner to keep on cheering for you! Looking forward to doing more amazing science together 💪

Check @katyappler.bsky.social thread below for highlights and the full paper here: rdcu.be/e4A70

Oxygen metabolism in descendants of the archaeal-eukaryotic ancestor - Nature Sequencing of marine sediments finds 136 newly identified Heimdallarchaeia and several novel lineages, and indicates that Heimdallarchaeia evolved distinct metabolic capabilities from other&nbsp;Asgar...

Hot eukaryogenesis news (is there any other kind?) - hydrogen production and aerobic respiration may have been present in the Asgard-eukaryotic ancestor - paper in @nature.com www.nature.com/articles/s41...

Postdoctoral position - Synthetic Biology / Bacterial Immunity - Research The Bikard lab at Institut Pasteur in Paris is seeking to hire postdoctoral researchers. We are investigating bacteria / bacteriophages interactions, and the genetic innovation that happens at this in...

🚨 Hiring Alert! 🚨My lab at Institut Pasteur is recruiting several Postdocs! We have exciting open projects in: 🦠 Synthetic Biology and🛡️ Bacterial Immunity. Come do great science with us in the middle of Paris! 🇫🇷🥐 research.pasteur.fr/en/job/postd...

New paper from my team detailing a greatly expanded genomic database of Asgard archaea revealing of high energy metabolism those related to eukaryotes! Led by @katyappler.bsky.social lots of help from @jameslingford.bsky.social @valdeanda.bsky.social @kassipan.bsky.social doi.org/10.1038/s415...

Congrats Katy 🗽🗽🗽
Figures are stunning.
Very eager to read
Bravo