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Posts by Eli Slenders

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#SPAD array detectors are transforming how we measure molecular diffusion and interactions. Our #Python code for #FFS analysis is now #opensource! www.biorxiv.org/content/10.6.... Compatible with various detectors! @picoquant.bsky.social #luminosa @genoainstruments.bsky.social @erc.europa.eu

1 week ago 4 0 0 0
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Pre-Doctoral Fellow in Smart Microscopy Commitment & contract: collaboration contract, 12 months Location: Centre for Human Technology, Via Enrico Melen, 83 Bldg. B 16152, Genoa Step into a world of endless possibilities, together let’s l...

Pre-Doctoral Fellow in #Smartmicroscopy
Our group at @iitalk.bsky.social is seeking a predoctoral fellow to work on smart microscopy, combining optical microscopy, advanced detectors, and data analysis.
app.ncoreplat.com/jobposition/...

#SPADarray #AI #python #photonresolvedmicroscopy

1 month ago 5 7 1 0
Optical investigation of Dynamical Systems About me

Excited to launch my lab Optical investigation of Dynamical Systems at @iitalk.bsky.social where we'll explore how optical #microscopy can reveal molecular diffusion. We are hiring a predoc and postdoc, funded by #erc.europa.eu! Interested? Check optodynamics.github.io or www.iit.it/it/openings

1 month ago 3 3 0 0
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Arrived in beautiful, picturesque #Bressanone for #PhysicsOfBiomolecules! Excited for the talks and discussions and to present @vicidominilab.bsky.social's work on #SPAD array detectors for #FCS. We also have open positions @iitalk.bsky.social in Genoa! Feel free to reach out! @erc.europa.eu

2 months ago 6 3 1 0

Andrea Bucci and Laurent Le will run two workshops on building a custom #PhotonResolvedMicroscopy system and generating great #ImageScanningMicroscopy images.
Thanks @iitalk.bsky.social @erc.europa.eu @genoainstruments.bsky.social and #PNRR RNA&GeneTheraphy for support. See you at #Mifobio2025

6 months ago 13 7 0 1

Great, Luciano! Thanks a lot for sharing your thoughts!

6 months ago 1 0 0 0
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Localization of single molecules with structured illumination and structured detection - Light: Science & Applications Light: Science & Applications - Localization of single molecules with structured illumination and structured detection

Happy to share this article with my views on @elislenders.bsky.social and @vicidominilab.bsky.social work and discussing current developments in single-molecule localization combining structured excitation and detection. So many exciting perspectives in the field!

www.nature.com/articles/s41...

6 months ago 23 10 2 0
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Very happy to be in #ThePhotonics100 list for 2026. Big thanks to everyone in @vicidominilab.bsky.social and to all collaborators for their continuous support!

6 months ago 3 2 1 0
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@vicidominilab.bsky.social arrived in Berlin for the single molecule workshop #ws30. Looking forward to the talks and discussions! If you're interested in the use of #spad array detectors for imaging and SM localization, don't miss the poster of my colleague Francesco tonight and my talk on Friday!

6 months ago 13 2 0 1

Thank you very much for your support, @vicidominilab.bsky.social! Looking forward to starting the project!

7 months ago 1 0 0 0
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The researcher Eli Slenders awarded ERC grant to develop new microscopes to detect the speed and position of biomolecules in cells - Talk iit Among the 30 winning projects that will be carried out in Italy, one has been awarded to Eli Slenders from the Istituto Italiano di Tecnologia in Genoa Building a new microscope capable of tracking mo...

🏆🆕🇪🇺 @elislenders.bsky.social, researcher of the IIT Molecular Microscopy and Spectroscopy unit @vicidominilab.bsky.social , coordinated by Giuseppe Vicidomini, has been awarded an #ERCStG by the @erc.europa.eu

opentalk.iit.it/en/the-resea...

7 months ago 13 4 1 0

Grateful to my colleagues at @vicidominilab.bsky.social @iitalk.bsky.social for their support in making this research possible, and to @erc.europa.eu and #MSCA for their support! 6/6

9 months ago 3 1 0 0

ISM-FLUX offers more than just a simple experimental setup! Discover how the doughnut-shaped illumination provides a homogeneous localization uncertainty over a large FOV and learn about the self-calibrating procedure of ISM-FLUX. Check out our paper for all the details. 5/6

9 months ago 2 1 1 0
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We tested ISM-FLUX on DNA-origami nanorulers, and achieved a median localization uncertainty below 5 nm for single molecules. This precision effortlessly resolved 40 nm and 20 nm nanorulers. 4/6

9 months ago 2 0 1 0
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Similar to #MINFLUX, our localization uncertainty scales with L/sqrt(N), with L the TCP diameter and N the number of photons. However, while MINFLUX requires the emitter to be within the scanned area, ISM-FLUX has a much larger localization range, making it more robust. 3/6

9 months ago 2 1 1 0
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ISM-FLUX makes use of a #SPAD array detector. This boosts localization range and offers flexibility in the scanned target coordinate pattern (TCP). We chose a circular pattern, enabled by galvanometric scan mirrors found in most LSMs. 2/6

9 months ago 3 1 1 0
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Array detection enables large localization range for simple and robust MINFLUX - Light: Science & Applications Light: Science & Applications - Array detection enables large localization range for simple and robust MINFLUX

Excited to share our paper on ISM-FLUX, our new #MINFLUX-based technology. Achieve sub-10 nm localization uncertainty on single molecules using a straightforward #confocal-based setup with an array detector. 1/6 www.nature.com/articles/s41...

9 months ago 12 4 1 0
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Our last paper on s²ISM (super-resolution sectioning #ImageScanningMicroscopy) just got published on Nature Photonics @natphoton.nature.com‬! Discover how structured detection in laser scanning microscopes enhances both resolution and optical sectioning:

www.nature.com/articles/s41...

🧵1/7

10 months ago 14 5 2 0